Comparable stake leader
TCG Crossover GP II, LLC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001653087.
Comparable stake leader
TCG Crossover GP II, LLC
Disclosed value leader
TCG Crossover GP II, LLC
Comparable rows
50/50
Latest evidence
31 Mar 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| TCG Crossover GP II, LLC |
13D/G
Chen Yu
|
9.2%
|
$29,600,000
10,000,000 shares
|
$0 | 22 Oct 2025 |
| Arnon Rosenthal |
13D/G
3/4/5
Chief Executive Officer, Director
|
7.4%
|
$12,813,723
8,213,925 shares
|
$0 | 31 Dec 2025 |
| BlackRock, Inc. |
13F
13D/G
Company
|
5.2%
from 13D/G
|
$16,643,677
7,741,245 shares
|
— | 31 Mar 2026 |
| Polaris Venture Partners VI, L.P. |
13D/G
Terrance G. McGuire
|
4.7%
|
$12,157,723
5,173,499 shares
|
-$4,516,117 | 31 Mar 2026 |
| FMR LLC |
13D/G
13F
Company
|
3.6%
|
$10,655,467
3,599,820 shares
|
$0 | 31 Oct 2025 |
| Marc Grasso |
3/4/5
Chief Financial Officer
|
0.27%
|
$396,262
296,072 shares
|
— | 02 Jun 2025 |
| TCG Crossover Management, LLC |
13F
Company
|
9.1%
|
$21,500,000
10,000,000 shares
|
— | 31 Mar 2026 |
| ACADIAN ASSET MANAGEMENT LLC |
13F
Company
|
3.7%
|
$8,675,000
4,038,785 shares
|
— | 31 Mar 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$1,019,689.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 126,764 | $0 | $250,861 | -$250,861 |
| 3-6 | 0 | 128,030 | $0 | $273,773 | -$273,773 |
| 6-9 | 0 | 196,104 | $0 | $219,987 | -$219,987 |
| 9-12 | 0 | 110,952 | $0 | $275,068 | -$275,068 |
Reporting owners
Showing 1-20 of 22 reporting-owner rows connected to Alector, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Polaris Venture Management Co. VI, L.L.C. | 10%+ Owner | $68,200,238 | Mixed | 29 May 2024 | ||
| Terrance McGuire | Director, 10%+ Owner | $60,653,001 | Mixed | 11 Sep 2023 | ||
| Tillman U. Gerngross | Director | $14,702,414 | Mixed | 14 Jun 2023 | ||
| Arnon Rosenthal | Chief Executive Officer, Director | $6,076,449 | -$591,579 | -8.9% | Mixed | 02 Jun 2026 |
| Robert King | Chief Development Officer | $3,062,843 | Mixed | 01 Oct 2022 | ||
| Robert Paul | Chief Medical Officer | $1,302,814 | Mixed | 09 Aug 2021 | ||
| Neil Lindsay Berkley | CFO & Chief Business Officer | $749,998 | -$182,446 | -20% | Filing P/S | 02 Jun 2026 |
| Shehnaaz Suliman | President and COO | $570,445 | Mixed | 10 Dec 2021 | ||
| Sara Kenkare-Mitra | President and Head of R&D | $561,649 | -$105,692 | -16% | Filing P/S | 03 Dec 2025 |
| David M. Wehner | Director | $553,434 | Mixed | 12 Jun 2024 | ||
| Gary Romano | Chief Medical Officer | $488,610 | Filing P/S | 03 Mar 2025 | ||
| Calvin Yu | Vice President, Finance | $426,374 | Mixed | 02 Jul 2021 | ||
| Marc Grasso | Chief Financial Officer | $396,262 | Filing P/S | 02 Jun 2025 | ||
| Louis J. Lavigne Jr. | Director | $298,120 | Mixed | 17 Jun 2026 | ||
| Richard H. Scheller | Director | $290,032 | Mixed | 17 Jun 2026 | ||
| Kristine Yaffe | Director | $266,834 | Mixed | 17 Jun 2026 | ||
| Elizabeth A. Garofalo | Director | $255,097 | Mixed | 17 Jun 2026 | ||
| Paula Hammond | Director | $222,759 | -$32,998 | -13% | Mixed | 17 Jun 2026 |
| Errol B. Desouza | Director | $212,097 | Mixed | 17 Jun 2026 | ||
| Mark Altmeyer | Director | $212,097 | Mixed | 17 Jun 2026 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Kristine Yaffe | ALEC | Common Stock | Award | 30.1% | 28,700 | 124,109 | 17 Jun 2026 | Direct | ||
| Kristine Yaffe | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Richard H. Scheller | ALEC | Common Stock | Award | 27% | 28,700 | 134,899 | 17 Jun 2026 | Direct | ||
| Richard H. Scheller | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Paula Hammond | ALEC | Common Stock | Award | 38.3% | 28,700 | 103,609 | 17 Jun 2026 | Direct | ||
| Paula Hammond | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Elizabeth A. Garofalo | ALEC | Common Stock | Award | 31.9% | 28,700 | 118,650 | 17 Jun 2026 | Direct | ||
| Elizabeth A. Garofalo | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Mark Altmeyer | ALEC | Common Stock | Award | 41% | 28,700 | 98,650 | 17 Jun 2026 | Direct | ||
| Mark Altmeyer | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Errol B. Desouza | ALEC | Common Stock | Award | 41% | 28,700 | 98,650 | 17 Jun 2026 | Direct | ||
| Errol B. Desouza | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Louis J. Lavigne Jr. | ALEC | Common Stock | Award | 28.9% | 28,700 | 128,109 | 17 Jun 2026 | Direct | ||
| Louis J. Lavigne Jr. | ALEC | Stock Option (right to buy) | Award | 9,450 | 9,450 | 17 Jun 2026 | Direct | |||
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -3.51% | $6,543 | $1.88 | -3,475 | 95,461 | 03 Jun 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -3.51% | $6,543 | $1.88 | -3,475 | 95,461 | 03 Jun 2026 | Direct |
| Arnon Rosenthal | ALEC | Common Stock | Sale | -3.55% | $172,191 | $1.97 | -87,216 | 2,367,206 | 02 Jun 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -5.46% | $11,271 | $1.97 | -5,709 | 98,936 | 02 Jun 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -5.46% | $11,271 | $1.97 | -5,709 | 98,936 | 02 Jun 2026 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Sale | -4.85% | $38,221 | $1.97 | -19,360 | 379,900 | 02 Jun 2026 | Direct |
| Richard H. Scheller | ALEC | Common Stock | Award | 11.4% | 10,833 | 106,199 | 01 Jun 2026 | Direct | ||
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -1.71% | $4,823 | $2.65 | -1,820 | 104,645 | 16 Apr 2026 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Award | 15.8% | 54,600 | 399,260 | 15 Mar 2026 | Direct | ||
| Arnon Rosenthal | ALEC | Common Stock | Award | 4.97% | 116,246 | 2,454,422 | 13 Mar 2026 | Direct | ||
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -0.93% | $2,650 | $2.65 | -1,000 | 106,465 | 10 Mar 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -3.04% | $7,012 | $2.08 | -3,367 | 107,465 | 03 Mar 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -6.79% | $17,138 | $2.12 | -8,071 | 110,832 | 02 Mar 2026 | Direct |
| Arnon Rosenthal | ALEC | Common Stock | Sale | -3.38% | $173,822 | $2.12 | -81,864 | 2,338,176 | 02 Mar 2026 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Sale | -7.92% | $62,954 | $2.12 | -29,649 | 344,660 | 02 Mar 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -3.32% | $10,198 | $2.50 | -4,079 | 118,903 | 26 Feb 2026 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -3.72% | $5,751 | $1.21 | -4,753 | 122,982 | 05 Dec 2025 | Direct |
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -5.93% | $9,019 | $1.12 | -8,056 | 127,735 | 03 Dec 2025 | Direct |
| Arnon Rosenthal | ALEC | Common Stock | Sale | -4.13% | $116,827 | $1.12 | -104,347 | 2,420,040 | 03 Dec 2025 | Direct |
| Sara Kenkare-Mitra | ALEC | Common Stock | Sale | -7.67% | $46,673 | $1.12 | -41,687 | 501,652 | 03 Dec 2025 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Sale | -9.05% | $41,717 | $1.12 | -37,261 | 374,309 | 03 Dec 2025 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Award | 18.8% | 65,000 | 411,570 | 10 Nov 2025 | Direct | ||
| Neil Lindsay Berkley | ALEC | Employee Stock Option (right to buy) | Award | 195,000 | 195,000 | 10 Nov 2025 | Direct | |||
| Grace Wong-Sarad | ALEC | Common Stock | Award | 31.3% | 32,343 | 135,791 | 10 Nov 2025 | Direct | ||
| Grace Wong-Sarad | ALEC | Employee Stock Option (right to buy) | Award | 48,535 | 48,535 | 10 Nov 2025 | Direct | |||
| Arnon Rosenthal | ALEC | Common Stock | Award | 7.41% | 174,167 | 2,524,387 | 10 Nov 2025 | Direct | ||
| Arnon Rosenthal | ALEC | Employee Stock Option (right to buy) | Award | 522,500 | 522,500 | 10 Nov 2025 | Direct | |||
| Grace Wong-Sarad | ALEC | Common Stock | Sale | -5.4% | $14,756 | $2.50 | -5,910 | 103,448 | 02 Sep 2025 | Direct |
| Neil Lindsay Berkley | ALEC | Common Stock | Sale | -4.37% | $39,554 | $2.50 | -15,842 | 346,570 | 02 Sep 2025 | Direct |
| Sara Kenkare-Mitra | ALEC | Common Stock | Sale | -4.17% | $59,019 | $2.50 | -23,638 | 543,339 | 02 Sep 2025 | Direct |
| Arnon Rosenthal | ALEC | Common Stock | Sale | -2.15% | $128,740 | $2.50 | -51,562 | 2,350,220 | 02 Sep 2025 | Direct |
| Paula Hammond | ALEC | Common Stock | Sale | -15.8% | $32,998 | $2.36 | -14,000 | 74,909 | 26 Aug 2025 | Direct |