Comparable stake leader
VANGUARD GROUP INC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001599901.
Comparable stake leader
VANGUARD GROUP INC
Disclosed value leader
Avoro Capital Advisors LLC
Comparable rows
8/10
Latest evidence
30 Jun 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
8 of 10 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| VANGUARD GROUP INC |
13D/G
The Vanguard Group
|
9.6%
|
$575,984,900
13,219,759 shares
|
$0 | 30 Sep 2025 |
| BlackRock, Inc. |
13D/G
|
6.4%
|
$376,086,262
8,631,771 shares
|
-$17,916,333 | 30 Sep 2025 |
| Avoro Capital Advisors LLC |
13D/G
|
5.5%
|
$614,244,077
8,515,792 shares
|
$0 | 31 Dec 2025 |
| Janus Henderson Group Ltd. |
13D/G
JANUS HENDERSON GROUP PLC
|
4.6%
|
$500,546,351
6,939,503 shares
|
-$92,717,850 | 31 Dec 2025 |
| RTW INVESTMENTS, LP |
13D/G
3/4/5
10%+ Owner
|
3.1%
|
$204,173,813
4,686,110 shares
|
$0 | 27 Oct 2025 |
| FMR LLC |
13D/G
|
2.1%
|
$128,911,093
2,958,712 shares
|
-$809,934,537 | 31 Oct 2025 |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
|
0.5%
|
$52,158,501
723,118 shares
|
-$646,388,523 | 31 Dec 2025 |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13D/G
T. Rowe Price Associates, Inc.
|
0.1%
|
$10,306,511
142,888 shares
|
-$695,695,581 | 31 Dec 2025 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$5,721,892.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 0 | $0 | $0 | $0 |
| 3-6 | 0 | 0 | $0 | $0 | $0 |
| 6-9 | 0 | 58,407 | $0 | $4,226,448 | -$4,226,448 |
| 9-12 | 0 | 30,979 | $0 | $1,495,444 | -$1,495,444 |
Reporting owners
Showing 1-19 of 19 reporting-owner rows connected to Avidity Biosciences, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 10%+ Owner | $48,573,350 | Mixed | 04 Aug 2021 | ||
| Simona Skerjanec | Director | $0 | Mixed | 27 Feb 2026 | ||
| Teresa McCarthy | Chief Human Resources Officer | $0 | -$1,357,196 | -100% | Mixed | 27 Feb 2026 |
| Sarah Boyce | President and CEO, Director | $0 | -$1,661,783 | -100% | Mixed | 27 Feb 2026 |
| Michael F. MacLean | Chief Financial Officer | $0 | -$471,650 | -100% | Mixed | 27 Feb 2026 |
| Carsten Boess | Director | $0 | Mixed | 27 Feb 2026 | ||
| Steven George Hughes | Chief Medical Officer | $0 | -$720,660 | -100% | Mixed | 27 Feb 2026 |
| Kathleen P. Gallagher | Chief Program Officer | $0 | Mixed | 27 Feb 2026 | ||
| Tamar Thompson | Director | $0 | Mixed | 27 Feb 2026 | ||
| Jean Jinsun Kim | Director | $0 | Mixed | 27 Feb 2026 | ||
| Edward M. Kaye MD | Director | $0 | Mixed | 27 Feb 2026 | ||
| Noreen Henig | Director | $0 | Mixed | 27 Feb 2026 | ||
| Charles Calderaro III | Chief Technical Officer | $0 | -$269,201 | -100% | Mixed | 27 Feb 2026 |
| Troy E. Wilson | Director | $0 | Mixed | 27 Feb 2026 | ||
| Arthur A. Levin | Director | $0 | -$127,367 | -100% | Mixed | 27 Feb 2026 |
| W. Michael Flanagan | Chief Scientific Officer | $0 | -$644,790 | -100% | Mixed | 27 Feb 2026 |
| John B. Moriarty Jr. | Chief Legal Officer | $0 | -$171,474 | -100% | Mixed | 27 Feb 2026 |
| Eric Mosbrooker | Chief Commercial Officer | $0 | -$297,771 | -100% | Mixed | 27 Feb 2026 |
| Roderick Wong | Director, 10%+ Owner | Mixed | 16 Jun 2021 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Teresa McCarthy | RNA | Common Stock | Disposed to Issuer | -100% | -165,296 | 0 | 27 Feb 2026 | Direct | ||
| Teresa McCarthy | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -518,500 | 0 | 27 Feb 2026 | Direct | ||
| Tamar Thompson | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Tamar Thompson | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -67,523 | 0 | 27 Feb 2026 | Direct | ||
| Michael F. MacLean | RNA | Common Stock | Disposed to Issuer | -100% | -133,977 | 0 | 27 Feb 2026 | Direct | ||
| Michael F. MacLean | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -587,375 | 0 | 27 Feb 2026 | Direct | ||
| Simona Skerjanec | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Simona Skerjanec | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -52,342 | 0 | 27 Feb 2026 | Direct | ||
| Steven George Hughes | RNA | Common Stock | Disposed to Issuer | -100% | -115,857 | 0 | 27 Feb 2026 | Direct | ||
| Steven George Hughes | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -315,133 | 0 | 27 Feb 2026 | Direct | ||
| Sarah Boyce | RNA | Common Stock | Disposed to Issuer | -100% | -474,861 | 0 | 27 Feb 2026 | Direct | ||
| Sarah Boyce | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -2,176,015 | 0 | 27 Feb 2026 | Direct | ||
| John B. Moriarty | RNA | Common Stock | Disposed to Issuer | -100% | -92,054 | 0 | 27 Feb 2026 | Direct | ||
| John B. Moriarty | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -210,000 | 0 | 27 Feb 2026 | Direct | ||
| W. Michael Flanagan | RNA | Common Stock | Disposed to Issuer | -100% | -150,365 | 0 | 27 Feb 2026 | Direct | ||
| W. Michael Flanagan | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -397,500 | 0 | 27 Feb 2026 | Direct | ||
| Troy Edward Wilson | RNA | Common Stock | Disposed to Issuer | -100% | -13,711 | 0 | 27 Feb 2026 | By family trust | ||
| Troy Edward Wilson | RNA | Common Stock | Disposed to Issuer | -100% | -65,091 | 0 | 27 Feb 2026 | Direct | ||
| Troy Edward Wilson | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -38,523 | 0 | 27 Feb 2026 | Direct | ||
| Kathleen P. Gallagher | RNA | Common Stock | Disposed to Issuer | -100% | -80,303 | 0 | 27 Feb 2026 | Direct | ||
| Kathleen P. Gallagher | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -208,330 | 0 | 27 Feb 2026 | Direct | ||
| Noreen Henig | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Noreen Henig | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -103,380 | 0 | 27 Feb 2026 | Direct | ||
| Jean Jinsun Kim | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Jean Jinsun Kim | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -97,523 | 0 | 27 Feb 2026 | Direct | ||
| Arthur A. Levin | RNA | Common Stock | Disposed to Issuer | -100% | -131,372 | 0 | 27 Feb 2026 | By family trust | ||
| Arthur A. Levin | RNA | Common Stock | Disposed to Issuer | -100% | -16,562 | 0 | 27 Feb 2026 | Direct | ||
| Arthur A. Levin | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -295,523 | 0 | 27 Feb 2026 | Direct | ||
| Edward M. Kaye MD | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Edward M. Kaye MD | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -103,380 | 0 | 27 Feb 2026 | Direct | ||
| Carsten Boess | RNA | Common Stock | Disposed to Issuer | -100% | -6,692 | 0 | 27 Feb 2026 | Direct | ||
| Carsten Boess | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -103,381 | 0 | 27 Feb 2026 | Direct | ||
| Eric Mosbrooker | RNA | Common Stock | Disposed to Issuer | -100% | -79,413 | 0 | 27 Feb 2026 | Direct | ||
| Eric Mosbrooker | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -227,188 | 0 | 27 Feb 2026 | Direct | ||
| Charles Calderaro III | RNA | Common Stock | Disposed to Issuer | -100% | -98,547 | 0 | 27 Feb 2026 | Direct | ||
| Charles Calderaro III | RNA | Stock Option (Right to Buy) | Disposed to Issuer | -100% | -80,000 | 0 | 27 Feb 2026 | Direct | ||
| Steven George Hughes | RNA | Common Stock | Sale | -13.4% | $354,643 | $72.45 | -4,895 | 31,599 | 21 Jan 2026 | Direct |
| Sarah Boyce | RNA | Common Stock | Sale | -5.08% | $1,042,338 | $72.45 | -14,387 | 269,007 | 21 Jan 2026 | Direct |
| W. Michael Flanagan | RNA | Common Stock | Sale | -7.13% | $473,388 | $72.45 | -6,534 | 85,093 | 21 Jan 2026 | Direct |
| Teresa McCarthy | RNA | Common Stock | Sale | -2.51% | $212,206 | $72.45 | -2,929 | 113,938 | 21 Jan 2026 | Direct |
| Michael F. MacLean | RNA | Common Stock | Sale | -7.12% | $329,068 | $72.45 | -4,542 | 59,290 | 21 Jan 2026 | Direct |
| Arthur A. Levin | RNA | Common Stock | Sale | -9.6% | $127,367 | $72.45 | -1,758 | 16,562 | 21 Jan 2026 | Direct |
| Sarah Boyce | RNA | Common Stock | Sale | -2.94% | $619,444 | $72.23 | -8,576 | 283,394 | 07 Jan 2026 | Direct |
| Charles Calderaro III | RNA | Common Stock | Sale | -6.96% | $269,201 | $72.23 | -3,727 | 49,797 | 07 Jan 2026 | Direct |
| Teresa McCarthy | RNA | Common Stock | Sale | -1.65% | $141,932 | $72.23 | -1,965 | 116,867 | 07 Jan 2026 | Direct |
| John B. Moriarty | RNA | Common Stock | Sale | -3.09% | $171,474 | $72.23 | -2,374 | 74,557 | 07 Jan 2026 | Direct |
| Michael F. MacLean | RNA | Common Stock | Sale | -3% | $142,582 | $72.23 | -1,974 | 63,832 | 07 Jan 2026 | Direct |
| Steven George Hughes | RNA | Common Stock | Sale | -6.11% | $171,402 | $72.23 | -2,373 | 36,494 | 07 Jan 2026 | Direct |
| W. Michael Flanagan | RNA | Common Stock | Sale | -2.52% | $171,402 | $72.23 | -2,373 | 91,627 | 07 Jan 2026 | Direct |
| Arthur A. Levin | RNA | Common Stock | Gift | -6.77% | -1,330 | 18,320 | 19 Dec 2025 | Direct |