SEC ownership of CASTLE BIOSCIENCES INC

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001447362.

Comparable stake leader

RTW INVESTMENTS, LP

Disclosed value leader

BlackRock, Inc.

Comparable rows

50/50

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
RTW INVESTMENTS, LP
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001447362
Issuer location
Friendswood, TX

Ownership snapshot

Top shareholders of CASTLE BIOSCIENCES INC (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
RTW INVESTMENTS, LP
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
13D/G 13F Lead comparable stake: 9.3% 13D/G row: RTW INVESTMENTS, LP Showing 1-8 of 50 holder rows.

Quick read

RTW INVESTMENTS, LP leads the comparable SEC ownership view at 9.3%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens RTW INVESTMENTS, LP's linked filing trail.
Comparable ownership Top 5
RTW INVESTMENTS, LP 9.3%
BlackRock, Inc. 8.2%
Portolan Capital Management, LLC 4.4%
DIMENSIONAL FUND ADVISORS LP 3.9%
WASATCH ADVISORS LP 3.5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
RTW INVESTMENTS, LP
13D/G 13F
Company
9.3%
$67,717,124
2,758,335 shares
+$15,788,056 31 Mar 2026
BlackRock, Inc.
13F 13D/G
Company
8.2%
from 13D/G
$78,513,319
3,291,963 shares
— 30 Jun 2026
Portolan Capital Management, LLC
13D/G 13F
Company
4.4%
$33,149,448
1,350,283 shares
-$6,403,033 31 Mar 2026
DIMENSIONAL FUND ADVISORS LP
13D/G 13F
Company
3.9%
$44,494,010
1,143,799 shares
-$12,848,347 31 Dec 2025
WASATCH ADVISORS LP
13D/G 13F
Company
3.5%
$20,078,930
998,455 shares
$0 31 Mar 2025
PRINCIPAL FINANCIAL GROUP INC
13F
Company
13F
5.7%
$41,180,555
1,726,648 shares
— 30 Jun 2026
VANGUARD CAPITAL MANAGEMENT LLC
13F
Company
13F
4%
$29,251,953
1,226,497 shares
— 30 Jun 2026
ACADIAN ASSET MANAGEMENT LLC
13F
Company
13F
3%
$21,897,000
918,668 shares
— 30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$18,883,623.

Buys
$0
Insiders: 0
Sells
$18,883,623
Insiders: 5
Net
-$18,883,623
Shares: -619,568
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 619,568
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 257,928 $0 $8,202,184 -$8,202,184
3-6 0 63,369 $0 $1,420,048 -$1,420,048
6-9 0 157,513 $0 $4,194,902 -$4,194,902
9-12 0 140,758 $0 $5,066,489 -$5,066,489

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-14 of 14 reporting-owner rows connected to CASTLE BIOSCIENCES INC. Open a relationship link for the CIK-to-CIK filing trail.

Rows
14
Largest Forms 3/4/5 holder
Derek J. Maetzold
Net 12M change
-$18,883,622
Latest report
05 Oct 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Derek J. Maetzold Pres. & Chief Exec. Officer, Director $12,426,661 -$11,178,818 -47% Mixed 05 Oct 2026
KABAKOFF DAVID S Director $10,282,139 Mixed 17 Jun 2021
Kristen M. Oelschlager Chief Operating Officer $3,368,229 -$3,336,196 -50% Mixed 01 Oct 2026
Tobin W. Juvenal Chief Commercial Officer $2,985,170 -$2,699,003 -47% Mixed 29 Sep 2026
Frank Stokes Chief Financial Officer $2,284,750 -$1,458,878 -39% Mixed 14 Aug 2026
Mara G. Aspinall Director $1,101,224 Mixed 23 May 2024
Rodney Cotton Director $1,018,142 Mixed 28 May 2026
Ellen Goldberg Director $1,004,610 Mixed 28 May 2026
Tiffany Olson Director $984,087 Mixed 28 May 2026
Kim Caple Director $886,770 Mixed 28 May 2026
Miles Harrison Director $874,741 Mixed 28 May 2026
Daniel Bradbury Director $874,741 Mixed 28 May 2026
G. Bradley Cole Director $809,560 -$210,727 -21% Mixed 28 May 2026
Bernhard E. Spiess Chief Business Officer $389,976 Mixed 10 Dec 2021

Recent insider transactions for CASTLE BIOSCIENCES INC

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Derek J. Maetzold CSTL Common Stock Sale -28.5% $96,668 $35.57 -2,718 6,832 05 Oct 2026 By Derek Maetzold 2020 Irrevocable Trust
Derek J. Maetzold CSTL Common Stock Sale -28.5% $113,740 $35.57 -3,198 8,038 05 Oct 2026 By The Maetzold Descendants 2020 Trust
Derek J. Maetzold CSTL Common Stock Sale -28.9% $305,156 $35.57 -8,580 21,064 05 Oct 2026 Direct
Derek J. Maetzold CSTL Common Stock Options Exercise 38% 8,165 29,644 05 Oct 2026 Direct
Derek J. Maetzold CSTL Stock option (right to buy) Options Exercise -100% -8,165 0 05 Oct 2026 Direct
Kristen M. Oelschlager CSTL Common Stock Sale -23.7% $149,318 $35.95 -4,153 13,356 01 Oct 2026 Direct
Kristen M. Oelschlager CSTL Common Stock Options Exercise 31.1% 4,153 17,509 01 Oct 2026 Direct
Kristen M. Oelschlager CSTL Stock option (right to buy) Options Exercise -33.3% -4,153 8,305 01 Oct 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -1.95% $35,363 $34.20 -1,034 52,007 30 Sep 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -9.46% $196,765 $35.50 -5,543 53,041 29 Sep 2026 Direct
Derek J. Maetzold CSTL Common Stock Sale -22.2% $96,038 $35.33 -2,718 9,550 21 Sep 2026 By Derek Maetzold 2020 Irrevocable Trust
Derek J. Maetzold CSTL Common Stock Sale -22.2% $112,998 $35.33 -3,198 11,236 21 Sep 2026 By The Maetzold Descendants 2020 Trust
Derek J. Maetzold CSTL Common Stock Sale -28.5% $303,166 $35.33 -8,580 21,479 21 Sep 2026 Direct
Derek J. Maetzold CSTL Common Stock Options Exercise 40% 8,580 30,059 21 Sep 2026 Direct
Derek J. Maetzold CSTL Stock option (right to buy) Options Exercise -51.2% -8,580 8,165 21 Sep 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -5.32% $115,758 $35.14 -3,294 58,584 15 Sep 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -5.07% $106,863 $32.32 -3,306 61,878 14 Sep 2026 Direct
Derek J. Maetzold CSTL Common Stock Sale -18.2% $87,319 $32.02 -2,727 12,268 11 Sep 2026 By Derek Maetzold 2020 Irrevocable Trust
Derek J. Maetzold CSTL Common Stock Sale -18.2% $102,689 $32.02 -3,207 14,434 11 Sep 2026 By The Maetzold Descendants 2020 Trust
Derek J. Maetzold CSTL Common Stock Sale -28.6% $274,862 $32.02 -8,584 21,479 11 Sep 2026 Direct
Derek J. Maetzold CSTL Common Stock Options Exercise 40% 8,584 30,063 11 Sep 2026 Direct
Derek J. Maetzold CSTL Stock option (right to buy) Options Exercise -33.9% -8,584 16,745 11 Sep 2026 Direct
Kristen M. Oelschlager CSTL Common Stock Sale -23.7% $138,643 $33.39 -4,152 13,356 01 Sep 2026 Direct
Kristen M. Oelschlager CSTL Common Stock Options Exercise 31.1% 4,152 17,508 01 Sep 2026 Direct
Kristen M. Oelschlager CSTL Stock option (right to buy) Options Exercise -25% -4,152 12,458 01 Sep 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -2.59% $56,761 $32.81 -1,730 65,184 31 Aug 2026 Direct
Derek J. Maetzold CSTL Common Stock Sale -2.41% $9,228 $33.20 -278 11,256 28 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.41% $9,228 $33.20 -278 11,256 28 Aug 2026 By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.41% $9,228 $33.20 -278 11,256 28 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.41% $9,228 $33.20 -278 11,256 28 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk
Derek J. Maetzold CSTL Common Stock Sale -13.3% $76,552 $33.20 -2,306 14,995 28 Aug 2026 By Derek Maetzold 2020 Irrevocable Trust
Derek J. Maetzold CSTL Common Stock Sale -13.3% $90,097 $33.20 -2,714 17,641 28 Aug 2026 By The Maetzold Descendants 2020 Trust
Derek J. Maetzold CSTL Common Stock Sale -36.6% $412,571 $33.20 -12,428 21,479 28 Aug 2026 Direct
Derek J. Maetzold CSTL Common Stock Options Exercise 57.9% 12,428 33,907 28 Aug 2026 Direct
Derek J. Maetzold CSTL Stock option (right to buy) Options Exercise -32.9% -12,428 25,329 28 Aug 2026 Direct
Tobin W. Juvenal CSTL Common Stock Sale -11.9% $317,112 $35.04 -9,050 66,914 25 Aug 2026 Direct
Kristen M. Oelschlager CSTL Common Stock Sale -14.6% $426,277 $34.42 -12,384 72,649 25 Aug 2026 The Fritz Shorter Trust
Kristen M. Oelschlager CSTL Common Stock Sale -12.6% $411,588 $33.69 -12,218 85,033 24 Aug 2026 The Fritz Shorter Trust
Tobin W. Juvenal CSTL Common Stock Sale -2.23% $51,191 $29.59 -1,730 75,964 17 Aug 2026 Direct
Frank Stokes CSTL Common Stock Sale -41.4% $741,511 $29.77 -24,908 35,177 14 Aug 2026 Direct
Derek J. Maetzold CSTL Common Stock Sale -2.35% $8,346 $30.02 -278 11,534 14 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.35% $8,346 $30.02 -278 11,534 14 Aug 2026 By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.35% $8,346 $30.02 -278 11,534 14 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold
Derek J. Maetzold CSTL Common Stock Sale -2.35% $8,346 $30.02 -278 11,534 14 Aug 2026 By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk
Derek J. Maetzold CSTL Common Stock Sale -11.8% $69,226 $30.02 -2,306 17,301 14 Aug 2026 By Derek Maetzold 2020 Irrevocable Trust
Derek J. Maetzold CSTL Common Stock Sale -11.8% $81,474 $30.02 -2,714 20,355 14 Aug 2026 By The Maetzold Descendants 2020 Trust
Derek J. Maetzold CSTL Common Stock Sale -4.87% $33,022 $30.02 -1,100 21,479 14 Aug 2026 Direct
Derek J. Maetzold CSTL Common Stock Options Exercise 5.12% 1,100 22,579 14 Aug 2026 Direct
Derek J. Maetzold CSTL Stock option (right to buy) Options Exercise -2.83% -1,100 37,757 14 Aug 2026 Direct
Derek J. Maetzold CSTL Common Stock Sale -2.36% $14,512 $30.68 -473 19,607 05 Aug 2026 By Derek Maetzold 2020 Irrevocable Trust
* marks a reported price that did not pass the local price check.
We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. Manage preferences to update or revoke optional consent for future visits. For more information, see our Privacy Policy .