Comparable stake leader
BlackRock, Inc.
SEC ownership of Protagonist Therapeutics, Inc
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001377121.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
- Public ticker
- PTGX on Nasdaq
- Parsed ownership sources
-
13F, 13D/G, and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
BlackRock, Inc.
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
50 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
BlackRock, Inc.
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
30 Jun 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001377121
- Issuer location
- Newark, CA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Protagonist Therapeutics, Inc (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
BlackRock, Inc.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
13F
13D/G
3/4/5
Lead comparable stake: 14%
13D/G row: BlackRock, Inc.
Showing 1-8 of 50 holder rows.
Quick read
BlackRock, Inc. leads the comparable SEC ownership view at 14%.
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens BlackRock, Inc.'s linked filing trail.
Comparable ownership
Top 5
BlackRock, Inc.
14%
FARALLON CAPITAL MANAGEMENT, L.L.C.
10%
Farallon Capital Partners, L.P.
10%
RTW INVESTMENTS, LP
8.1%
VANGUARD PORTFOLIO MANAGEMENT LLC
5.5%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| BlackRock, Inc. |
13F
13D/G
Company
|
14%
from 13D/G
|
$1,263,534,678
10,307,837 shares
|
— | 30 Jun 2026 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. |
13D/G
13F
Company
|
10%
|
$835,597,827
6,433,119 shares
|
$0 | 30 Jun 2026 |
| Farallon Capital Partners, L.P. |
13D/G
Dapice Joshua J.
|
10%
|
$545,701,455
6,248,013 shares
|
+$25,461,794 | 31 Dec 2025 |
| RTW INVESTMENTS, LP |
13F
13D/G
Company
|
8.1%
from 13D/G
|
$620,398,832
5,061,175 shares
|
— | 30 Jun 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
13F
13D/G
Company · Vanguard Portfolio Management
|
5.5%
from 13D/G
|
$444,879,349
3,629,298 shares
|
— | 30 Jun 2026 |
| STATE STREET CORP |
13D/G
13F
STATE STREET CORPORATION · Company
|
5.2%
|
$431,436,649
3,321,554 shares
|
+$26,594,978 | 30 Jun 2026 |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
13D/G
Company
|
5.1%
from 13D/G
|
$418,829,015
3,416,781 shares
|
— | 30 Jun 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13F
13D/G
Company · Vanguard Capital Management
|
5.1%
from 13D/G
|
$349,769,037
2,853,394 shares
|
— | 30 Jun 2026 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$62,395,766.
Buys
$0
Insiders: 0
Sells
$62,395,766
Insiders: 7
Net
-$62,395,766
Shares: -608,224
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 608,224
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 118,000 | $0 | $16,921,379 | -$16,921,379 |
| 3-6 | 0 | 263,345 | $0 | $26,707,266 | -$26,707,266 |
| 6-9 | 0 | 208,167 | $0 | $17,300,745 | -$17,300,745 |
| 9-12 | 0 | 18,712 | $0 | $1,466,376 | -$1,466,376 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-13 of 13 reporting-owner rows connected to Protagonist Therapeutics, Inc. Open a relationship link for the CIK-to-CIK filing trail.
Rows
13
Largest Forms 3/4/5 holder
Ph.D. Dinesh V Patel
Net 12M change
-$62,395,766
Latest report
10 Aug 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Ph.D. Dinesh V Patel | President and CEO, Director | $77,746,952 | -$34,828,688 | -31% | Filing P/S | 10 Aug 2026 |
| Arturo Molina MD | Chief Medical Officer | $8,814,410 | -$4,491,766 | -34% | Filing P/S | 26 Mar 2026 |
| Harold E. Selick | Director | $6,388,725 | -$2,520,000 | -28% | Filing P/S | 26 Mar 2026 |
| Asif Ali | Chief Financial Officer | $6,223,046 | -$7,315,452 | -54% | Filing P/S | 20 Apr 2026 |
| David Y. Liu | Chief R&D Strategy Officer | $4,127,742 | Mixed | 16 Nov 2022 | ||
| Suneel Gupta | Chief Development Officer | $3,254,660 | Mixed | 25 Nov 2024 | ||
| Bryan Giraudo | Director | $1,269,500 | -$5,918,880 | -82% | Filing P/S | 07 May 2026 |
| William D. Waddill | Director | $922,880 | -$5,837,420 | -86% | Filing P/S | 23 Jun 2026 |
| Sarah A. O'Dowd | Director | $683,433 | Mixed | 02 Jan 2026 | ||
| Lewis T. "rusty" Williams | Director | $644,936 | -$1,483,560 | -70% | Filing P/S | 17 Feb 2026 |
| Donald A. Kalkofen | Chief Financial Officer | $456,172 | Mixed | 15 Feb 2022 | ||
| Daniel N. Swisher Jr. | Director | Mixed | 26 Oct 2023 | |||
| Sarah B. Noonberg | Director | Mixed | 16 Jan 2023 |
Recent insider transactions for Protagonist Therapeutics, Inc
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Sale | -6.14% | $5,085,176 | $148.52 | -34,239 | 523,478 | 11 Aug 2026 | Direct |
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Options Exercise | 6.54% | 34,239 | 557,717 | 11 Aug 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Stock Option (right to buy) | Options Exercise | -21.5% | -34,239 | 125,000 | 11 Aug 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Sale | -11.2% | $9,805,623 | $149.11 | -65,761 | 523,478 | 10 Aug 2026 | Direct |
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Options Exercise | 12.6% | 65,761 | 589,239 | 10 Aug 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Stock Option (right to buy) | Options Exercise | -29.2% | -65,761 | 159,239 | 10 Aug 2026 | Direct | ||
| William D. Waddill | PTGX | Common Stock | Sale | -53.5% | $1,061,460 | $117.94 | -9,000 | 7,825 | 23 Jun 2026 | Direct |
| William D. Waddill | PTGX | Common Stock | Options Exercise | 115% | 9,000 | 16,825 | 23 Jun 2026 | Direct | ||
| William D. Waddill | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -9,000 | 0 | 23 Jun 2026 | Direct | ||
| William D. Waddill | PTGX | Common Stock | Sale | -53.5% | $969,120 | $107.68 | -9,000 | 7,825 | 10 Jun 2026 | Direct |
| William D. Waddill | PTGX | Common Stock | Options Exercise | 115% | 9,000 | 16,825 | 10 Jun 2026 | Direct | ||
| William D. Waddill | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -9,000 | 0 | 10 Jun 2026 | Direct | ||
| William D. Waddill | PTGX | Common Stock | Sale | -53.5% | $896,760 | $99.64 | -9,000 | 7,825 | 29 May 2026 | Direct |
| William D. Waddill | PTGX | Common Stock | Options Exercise | 115% | 9,000 | 16,825 | 29 May 2026 | Direct | ||
| William D. Waddill | PTGX | Stock Option (right to buy) | Options Exercise | -75% | -9,000 | 3,000 | 29 May 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Sale | -12.5% | $7,509,000 | $100.12 | -75,000 | 523,478 | 12 May 2026 | Direct |
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Options Exercise | 14.3% | 75,000 | 598,478 | 12 May 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Stock Option (right to buy) | Options Exercise | -25% | -75,000 | 225,000 | 12 May 2026 | Direct | ||
| Bryan Giraudo | PTGX | Common Stock | Sale | -28.8% | $513,000 | $100.00 | -5,130 | 12,695 | 08 May 2026 | Direct |
| Bryan Giraudo | PTGX | Common Stock | Sale | -100% | $600,000 | $100.00 | -6,000 | 0 | 08 May 2026 | By Bryan & Courtney Giraudo Trust |
| Bryan Giraudo | PTGX | Common Stock | Sale | -66.7% | $1,200,840 | $100.07 | -12,000 | 6,000 | 07 May 2026 | By Bryan & Courtney Giraudo Trust |
| Bryan Giraudo | PTGX | Common Stock | Sale | -56.4% | $3,605,040 | $100.14 | -36,000 | 27,825 | 07 May 2026 | Direct |
| Bryan Giraudo | PTGX | Common Stock | Options Exercise | 460.1% | 36,000 | 43,825 | 07 May 2026 | Direct | ||
| Bryan Giraudo | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -36,000 | 0 | 07 May 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Gift | -0.28% | -1,460 | 523,478 | 23 Apr 2026 | Direct | ||
| Asif Ali | PTGX | Common Stock | Sale | -2.88% | $184,572 | $105.47 | -1,750 | 59,003 | 20 Apr 2026 | Direct |
| Arturo Molina MD | PTGX | Common Stock | Sale | -15.1% | $1,571,850 | $104.79 | -15,000 | 84,115 | 26 Mar 2026 | Direct |
| Arturo Molina MD | PTGX | Common Stock | Options Exercise | 17.8% | 15,000 | 99,115 | 26 Mar 2026 | Direct | ||
| Arturo Molina MD | PTGX | Stock Option (right to buy) | Options Exercise | -22.7% | -15,000 | 50,971 | 26 Mar 2026 | Direct | ||
| Harold E. Selick | PTGX | Common Stock | Sale | -28.3% | $2,520,000 | $105.00 | -24,000 | 60,845 | 26 Mar 2026 | Direct |
| Harold E. Selick | PTGX | Common Stock | Options Exercise | 39.4% | 24,000 | 84,845 | 26 Mar 2026 | Direct | ||
| Harold E. Selick | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -24,000 | 0 | 26 Mar 2026 | Direct | ||
| Asif Ali | PTGX | Common Stock | Sale | -29% | $2,581,504 | $104.24 | -24,765 | 60,753 | 26 Mar 2026 | Direct |
| Asif Ali | PTGX | Common Stock | Options Exercise | 40.8% | 24,765 | 85,518 | 26 Mar 2026 | Direct | ||
| Asif Ali | PTGX | Stock Option (right to buy) | Options Exercise | -65.1% | -24,765 | 13,282 | 26 Mar 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Sale | -9.43% | $5,518,741 | $101.00 | -54,641 | 524,938 | 25 Mar 2026 | Direct |
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Options Exercise | 10.4% | 54,641 | 579,579 | 25 Mar 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -54,641 | 0 | 25 Mar 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Sale | -0.01% | $5,959 | $101.00 | -59 | 524,938 | 24 Mar 2026 | Direct |
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Options Exercise | 0.01% | 59 | 524,997 | 24 Mar 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Stock Option (right to buy) | Options Exercise | -0.11% | -59 | 54,641 | 24 Mar 2026 | Direct | ||
| Ph.D. Dinesh V Patel | PTGX | Common Stock | Gift | -8.7% | -50,000 | 524,938 | 23 Mar 2026 | Direct | ||
| Lewis T. "rusty" Williams | PTGX | Common Stock | Sale | -69.7% | $1,483,560 | $82.42 | -18,000 | 7,825 | 17 Feb 2026 | Direct |
| Lewis T. "rusty" Williams | PTGX | Common Stock | Options Exercise | 230% | 18,000 | 25,825 | 17 Feb 2026 | Direct | ||
| Lewis T. "rusty" Williams | PTGX | Stock Option (right to buy) | Options Exercise | 18,000 | 6,000 | 17 Feb 2026 | Direct | |||
| William D. Waddill | PTGX | Common Stock | Sale | -71.9% | $1,673,600 | $83.68 | -20,000 | 7,825 | 06 Feb 2026 | Direct |
| William D. Waddill | PTGX | Common Stock | Options Exercise | 255.6% | 20,000 | 27,825 | 06 Feb 2026 | Direct | ||
| William D. Waddill | PTGX | Stock Option (right to buy) | Options Exercise | -100% | -20,000 | 0 | 06 Feb 2026 | Direct | ||
| Asif Ali | PTGX | Common Stock | Sale | -43.4% | $3,841,037 | $83.13 | -46,203 | 60,320 | 27 Jan 2026 | Direct |
| Asif Ali | PTGX | Common Stock | Options Exercise | 35.7% | 28,000 | 106,523 | 27 Jan 2026 | Direct |
* marks a reported price that did not pass the local price check.