SEC ownership of ANAPTYSBIO, INC

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001370053.

Comparable stake leader

BlackRock, Inc.

Disclosed value leader

EcoR1 Capital, LLC

Comparable rows

50/50

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
BlackRock, Inc.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001370053
Issuer location
San Diego, CA

Ownership snapshot

Top shareholders of ANAPTYSBIO, INC (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
BlackRock, Inc.
Disclosed value leader
EcoR1 Capital, LLC
Comparable rows
50/50
Latest evidence
30 Jun 2026
13F 13D/G 3/4/5 Lead comparable stake: 6.2% 13D/G row: BlackRock, Inc. Showing 1-8 of 50 holder rows.

Quick read

BlackRock, Inc. leads the comparable SEC ownership view at 6.2%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BlackRock, Inc.'s linked filing trail.
Comparable ownership Top 5
BlackRock, Inc. 6.2%
Sirenia Capital Management LP 5%
GOLDMAN SACHS GROUP INC 4.5%
MORGAN STANLEY 3.6%
First Light Asset Management, LLC 3.1%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
BlackRock, Inc.
13F 13D/G
Company
6.2%
from 13D/G
$124,473,310
1,844,049 shares
30 Jun 2026
Sirenia Capital Management LP
13D/G
5%
$99,051,158
1,491,959 shares
-$28,444,331 30 Jun 2026
GOLDMAN SACHS GROUP INC
13F 13D/G
Company · THE GOLDMAN SACHS GROUP, INC.
4.5%
from 13D/G
$39,424,725
584,070 shares
30 Jun 2026
MORGAN STANLEY
13D/G 13F
Company
3.6%
$45,484,108
1,006,063 shares
-$37,928,432 31 Dec 2025
First Light Asset Management, LLC
13F 13D/G
Company · Mathew P. Arens
3.1%
from 13D/G
$39,285,270
582,004 shares
30 Jun 2026
MILLENNIUM MANAGEMENT LLC
13F 13D/G
Company
2.9%
from 13D/G
$54,493,830
807,316 shares
30 Jun 2026
FMR LLC
13F 13D/G
Company
0.9%
from 13D/G
$16,234,486
240,511 shares
30 Jun 2026
Frazier Life Sciences Public Fund, L.P.
13D/G
0.5%
$0 31 Jan 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$9,741,694.

Buys
$0
Insiders: 0
Sells
$9,741,694
Insiders: 7
Net
-$9,741,694
Shares: -202,844
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 202,844
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 38,324 $0 $2,247,650 -$2,247,650
6-9 0 156,280 $0 $7,255,084 -$7,255,084
9-12 0 8,240 $0 $238,960 -$238,960

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-18 of 18 reporting-owner rows connected to ANAPTYSBIO, INC. Open a relationship link for the CIK-to-CIK filing trail.

Rows
18
Largest Forms 3/4/5 holder
EcoR1 Capital, LLC
Net 12M change
-$9,741,694
Latest report
15 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
EcoR1 Capital, LLC Director, 10%+ Owner $102,051,945 Filing P/S 30 Dec 2024
Daniel Faga President, CEO, Director $34,118,977 -$2,805,072 -7.6% Mixed 20 Apr 2026
Paul F. Lizzul Chief Medical Officer $2,403,484 -$521,526 -18% Mixed 12 Mar 2026
John P. Schmid Director $2,180,438 -$1,158,451 -35% Mixed 15 Jun 2026
Dennis Mulroy Chief Financial Officer $1,387,042 -$1,549,332 -53% Mixed 07 Jan 2026
Eric J. Loumeau Chief Legal Officer $1,053,405 -$2,983,439 -74% Mixed 11 Feb 2026
John A. Orwin Director $1,018,163 Mixed 15 Jun 2026
Hollings Renton Director $702,041 Mixed 15 Jun 2026
Magda Marquet Director $577,329 -$530,531 -48% Mixed 15 Jan 2026
J. Anthony Ware Director $569,666 -$193,343 -25% Mixed 06 Jan 2026
Rita Jain Director $359,910 Mixed 06 Jan 2026
Dennis M. Fenton Director $211,270 Mixed 06 Jan 2026
James N. Topper Director, 10%+ Owner $85,059 Mixed 06 Jan 2023
Laura Jean Hamill Director $85,059 Mixed 06 Jan 2023
Susannah Gray Director Mixed 27 Apr 2026
Christopher M. Murphy Chief Financial Officer Mixed 11 May 2026
Owen Hughes Director Mixed 11 May 2026
Hamza Suria President, CEO, Director Mixed 10 Feb 2022

Recent insider transactions for ANAPTYSBIO, INC

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
John P. Schmid ANAB Common Stock Options Exercise 19.1% 6,030 37,652 15 Jun 2026 Direct
John P. Schmid ANAB Restricted Stock Unit Options Exercise -100% -6,030 0 15 Jun 2026 Direct
Hollings Renton ANAB Common Stock Options Exercise 121.4% 6,030 10,995 15 Jun 2026 Direct
Hollings Renton ANAB Restricted Stock Unit Options Exercise -100% -6,030 0 15 Jun 2026 Direct
John A. Orwin ANAB Common Stock Options Exercise 56.5% 6,030 16,695 15 Jun 2026 Direct
John A. Orwin ANAB Restricted Stock Unit Options Exercise -100% -6,030 0 15 Jun 2026 Direct
Owen Hughes ANAB Restricted Stock Units Award 11,250 11,250 11 May 2026 Direct
Christopher M. Murphy ANAB Restricted Stock Units Award 25,765 25,765 11 May 2026 Direct
Susannah Gray ANAB Restricted Stock Unit Award 11,250 11,250 27 Apr 2026 Direct
Daniel Faga ANAB Employee Stock Option (right to buy) Disposed to Issuer -50% -11,000 11,000 20 Apr 2026 Direct
John A. Orwin ANAB Stock Option (right to buy) Award 38,671 16,510 20 Apr 2026 Direct
John A. Orwin ANAB Stock Option (right to buy) Disposed to Issuer -92.1% -38,671 3,311 20 Apr 2026 Direct
John P. Schmid ANAB Stock Option (right to buy) Award 73,810 16,510 20 Apr 2026 Direct
John P. Schmid ANAB Stock Option (right to buy) Disposed to Issuer -93.1% -73,810 5,500 20 Apr 2026 Direct
Hollings Renton ANAB Stock Option (right to buy) Award 73,810 16,510 20 Apr 2026 Direct
Hollings Renton ANAB Stock Option (right to buy) Disposed to Issuer -93.1% -73,810 5,500 20 Apr 2026 Direct
John P. Schmid ANAB Common Stock Sale -39.5% $1,158,451 $56.11 -20,645 31,622 30 Mar 2026 Direct
Daniel Faga ANAB Common Stock Sale -3.44% $1,089,199 $61.61 -17,679 495,965 27 Mar 2026 Direct
Daniel Faga ANAB Common Stock Award 7.16% 34,300 513,644 25 Mar 2026 Direct
Paul F. Lizzul ANAB Performance Stock Units Award 16,667 16,667 12 Mar 2026 Direct
Daniel Faga ANAB Performance Stock Units Award 53,334 53,334 12 Mar 2026 Direct
Eric J. Loumeau ANAB Common Stock Sale -43.8% $540,000 $54.00 -10,000 12,835 11 Feb 2026 Direct
Eric J. Loumeau ANAB Common Stock Options Exercise 77.9% 10,000 22,835 11 Feb 2026 Direct
Eric J. Loumeau ANAB Employee Stock Option (right to buy) Options Exercise -22.2% -10,000 35,000 11 Feb 2026 Direct
Magda Marquet ANAB Common Stock Sale -52.6% $530,531 $48.23 -11,000 9,930 15 Jan 2026 Direct
Magda Marquet ANAB Common Stock Options Exercise 110.8% 11,000 20,930 15 Jan 2026 Direct
Magda Marquet ANAB Stock Option (right to buy) Options Exercise -100% -11,000 0 15 Jan 2026 Direct
Paul F. Lizzul ANAB Common Stock Sale -7.98% $163,192 $44.71 -3,650 42,088 08 Jan 2026 Direct
Dennis Mulroy ANAB Common Stock Sale -10.3% $112,446 $44.71 -2,515 21,852 08 Jan 2026 Direct
Eric J. Loumeau ANAB Common Stock Sale -14.7% $98,809 $44.71 -2,210 12,835 08 Jan 2026 Direct
Daniel Faga ANAB Common Stock Sale -2.89% $638,504 $44.71 -14,281 479,344 08 Jan 2026 Direct
Paul F. Lizzul ANAB Common Stock Options Exercise 22.9% 8,525 45,738 07 Jan 2026 Direct
Paul F. Lizzul ANAB Restricted Stock Unit Options Exercise -25% -8,525 25,575 07 Jan 2026 Direct
Dennis Mulroy ANAB Common Stock Options Exercise 37.9% 6,700 24,367 07 Jan 2026 Direct
Dennis Mulroy ANAB Restricted Stock Unit Options Exercise -25% -6,700 20,100 07 Jan 2026 Direct
Eric J. Loumeau ANAB Common Stock Options Exercise 64.3% 5,888 15,045 07 Jan 2026 Direct
Eric J. Loumeau ANAB Restricted Stock Unit Options Exercise -25% -5,888 17,662 07 Jan 2026 Direct
Daniel Faga ANAB Common Stock Options Exercise 5.75% 26,838 493,625 07 Jan 2026 Direct
Daniel Faga ANAB Restricted Stock Unit Options Exercise -25% -26,838 80,512 07 Jan 2026 Direct
Eric J. Loumeau ANAB Common Stock Sale -51.3% $439,200 $45.56 -9,639 9,157 07 Jan 2026 Direct
Paul F. Lizzul ANAB Common Stock Sale -5.67% $100,821 $45.11 -2,235 37,213 07 Jan 2026 Direct
Daniel Faga ANAB Common Stock Sale -1.93% $415,102 $45.11 -9,202 466,787 07 Jan 2026 Direct
Dennis Mulroy ANAB Common Stock Sale -9.75% $86,070 $45.11 -1,908 17,667 07 Jan 2026 Direct
Eric J. Loumeau ANAB Common Stock Options Exercise 41.8% 5,545 18,796 06 Jan 2026 Direct
Eric J. Loumeau ANAB Stock Option (right to buy) Award 23,200 23,200 06 Jan 2026 Direct
Eric J. Loumeau ANAB Restricted Stock Unit Award 17,100 17,100 06 Jan 2026 Direct
Eric J. Loumeau ANAB Restricted Stock Unit Options Exercise -50% -5,545 5,545 06 Jan 2026 Direct
Paul F. Lizzul ANAB Common Stock Options Exercise 18.4% 6,145 39,448 06 Jan 2026 Direct
Paul F. Lizzul ANAB Stock Option (right to buy) Award 29,000 29,000 06 Jan 2026 Direct
Paul F. Lizzul ANAB Restricted Stock Unit Award 21,400 21,400 06 Jan 2026 Direct
* marks a reported price that did not pass the local price check.
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