Security Snapshot

ANAPTYSBIO, INC - Common Stock (ANAB) Institutional Ownership

CUSIP: 032724106

13F Institutional Holders and Ownership History from Q1 2017 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

177

Shares (Excl. Options)

29,355,841

Price

$48.48

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Type / Class
Equity / Common Stock
Symbol
ANAB on Nasdaq
Shares outstanding
27,946,194
Price per share
$55.46
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
29,355,841
Total reported value
$1,422,981,231
% of total 13F portfolios
0%
Share change
-2,428,105
Value change
-$87,271,462
Number of holders
177
Price from insider filings
$55.46
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • ANAB - ANAPTYSBIO, INC - Common Stock is tracked under CUSIP 032724106.
  • 177 institutions reported positions in Q4 2025.
  • 7 significant owners is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 177 to 13 between Q4 2025 and Q1 2026.
  • Reported value moved from $1,422,981,231 to $3,831,538.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 177 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 032724106?
CUSIP 032724106 identifies ANAB - ANAPTYSBIO, INC - Common Stock in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of ANAPTYSBIO, INC - Common Stock (ANAB) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Point72 Asset Management, L.P. 7.7% +35% $49,025,259 +$14,013,859 2,368,370 +40% Point72 Asset Management, L.P. 31 Mar 2025
BlackRock, Inc. 6.2% -28% $39,347,471 -$13,405,817 1,900,844 -25% BlackRock, Inc. 31 Mar 2025
GOLDMAN SACHS GROUP INC 4.5% -14% $38,314,646 -$10,329,933 1,251,295 -21% THE GOLDMAN SACHS GROUP, INC. 30 Sep 2025
MORGAN STANLEY 3.6% -45% $45,484,108 -$37,928,432 1,006,063 -45% Morgan Stanley 31 Dec 2025
First Light Asset Management, LLC 3.1% -57% $26,474,603 -$42,907,347 864,618 -62% Mathew P. Arens 30 Sep 2025
MILLENNIUM MANAGEMENT LLC 2.9% -44% $39,442,003 -$29,733,912 813,571 -43% Millennium Management LLC 31 Dec 2025
FMR LLC 0.9% -88% $5,091,861 -$33,068,368 254,212 -87% FMR LLC 30 May 2025

As of 31 Dec 2025, 177 institutional investors reported holding 29,355,841 shares of ANAPTYSBIO, INC - Common Stock (ANAB). This represents 105% of the company’s total 27,946,194 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ANAPTYSBIO, INC - Common Stock (ANAB) together control 90% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
EcoR1 Capital, LLC 28% 7,880,094 0% 18% $382,026,957
Point72 Asset Management, L.P. 6.9% 1,932,890 -15% 0.15% $93,706,507
BlackRock, Inc. 6.2% 1,734,430 +0.7% 0% $84,085,167
VANGUARD GROUP INC 5.5% 1,544,037 +4.5% 0% $74,854,914
TANG CAPITAL MANAGEMENT LLC 4.8% 1,332,087 -0.12% 3.2% $64,579,578
STATE STREET CORP 3.8% 1,053,474 +21% 0% $51,072,420
MORGAN STANLEY 3.7% 1,034,562 -34% 0% $50,155,606
Sanofi 2.9% 821,917 0% 13% $39,846,536
MILLENNIUM MANAGEMENT LLC 2.9% 813,571 -46% 0.03% $39,441,922
Palo Alto Investors LP 2.5% 690,032 +2.5% 4.7% $33,452,751
D. E. Shaw & Co., Inc. 2.4% 670,288 +92% 0.02% $32,495,563
683 Capital Management, LLC 2.3% 648,093 +18% 2.6% $31,419,548
First Light Asset Management, LLC 2.3% 646,238 -35% 2.4% $31,329,618
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 2% 559,744 +51% 0.02% $27,136,389
Woodline Partners LP 1.8% 501,023 0% 0.09% $24,289,595
GEODE CAPITAL MANAGEMENT, LLC 1.7% 469,494 -0.87% 0% $22,766,046
Affinity Asset Advisors, LLC 1.6% 444,692 1.5% $21,558,668
GOLDMAN SACHS GROUP INC 1.4% 398,914 +21% 0% $19,339,351
TWO SIGMA ADVISERS, LP 1.3% 356,700 -4.5% 0.03% $17,292,816
Nuveen, LLC 1.1% 316,685 -6.7% 0% $15,352,889
FEDERATED HERMES, INC. 1.1% 299,416 +55% 0.02% $14,515,687
Sofinnova Investments, Inc. 1% 287,690 +13% 0.6% $13,947,211
TWO SIGMA INVESTMENTS, LP 0.92% 256,635 +0.08% 0.02% $12,441,665
VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.82% 229,137 +2358% 0.04% $11,108,562
Ensign Peak Advisors, Inc 0.77% 215,454 0% 0.02% $10,445,210

Institutional Holders of ANAPTYSBIO, INC - Common Stock (ANAB) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 69,082 $3,831,538 +$1,573,152 $55.46 13
2025 Q4 29,355,841 $1,422,981,231 -$87,271,462 $48.48 177
2025 Q3 31,623,561 $968,590,879 -$154,422,366 $30.62 164
2025 Q2 36,775,405 $816,417,703 -$61,528,593 $22.20 146
2025 Q1 39,955,702 $742,780,741 +$106,646,664 $18.59 150
2024 Q4 35,417,634 $468,934,603 -$87,874,690 $13.24 133
2024 Q3 33,628,905 $1,126,906,586 +$123,178,333 $33.50 158
2024 Q2 29,795,998 $746,647,480 +$18,365,650 $25.06 133
2024 Q1 29,220,936 $658,049,704 -$20,954,780 $22.52 132
2023 Q4 30,178,929 $646,434,520 +$661,774 $21.42 117
2023 Q3 30,319,401 $544,539,672 -$1,742,551 $17.96 116
2023 Q2 30,230,678 $614,916,059 -$16,322,967 $20.34 116
2023 Q1 31,038,362 $675,357,489 -$44,703,594 $21.76 112
2022 Q4 32,881,839 $1,018,995,107 -$10,549,644 $30.99 114
2022 Q3 32,565,742 $830,751,663 +$39,360,338 $25.51 109
2022 Q2 31,163,975 $632,623,400 +$28,483,649 $20.30 117
2022 Q1 29,681,010 $735,000,699 +$13,953,506 $24.74 124
2021 Q4 27,753,009 $964,436,533 +$8,862,117 $34.75 132
2021 Q3 27,612,274 $748,805,223 -$4,361,131 $27.12 123
2021 Q2 27,792,119 $720,641,941 -$34,119,008 $25.93 117
2021 Q1 29,170,513 $628,617,724 +$26,204,184 $21.55 116
2020 Q4 27,945,751 $600,836,464 -$16,682,226 $21.50 129
2020 Q3 29,118,815 $429,506,449 -$16,534,668 $14.75 127
2020 Q2 29,995,726 $670,116,259 -$17,219,808 $22.34 117
2020 Q1 31,226,700 $441,231,854 +$44,124,506 $14.13 112
2019 Q4 28,278,193 $459,515,291 -$210,904,567 $16.25 119
2019 Q3 29,041,948 $1,016,180,867 -$48,935,396 $34.99 118
2019 Q2 30,188,598 $1,703,071,412 +$118,485,533 $56.42 126
2019 Q1 29,116,728 $2,126,815,017 +$19,403,624 $73.05 128
2018 Q4 28,960,221 $1,847,302,433 -$11,161,189 $63.79 120
2018 Q3 28,571,805 $2,850,575,697 +$379,454,311 $99.77 127
2018 Q2 24,854,220 $1,765,626,873 +$925,670 $71.04 121
2018 Q1 24,343,157 $2,533,621,510 +$62,752,765 $104.08 134
2017 Q4 23,775,515 $2,394,657,180 +$692,566,246 $100.72 116
2017 Q3 17,730,856 $619,647,150 +$143,400,869 $34.95 70
2017 Q2 13,703,868 $327,947,635 -$2,477,474 $23.93 51
2017 Q1 13,764,320 $381,565,000 +$374,641,000 $27.75 48