ANAPTYSBIO, INC - Common Stock, $0.01 par value (ANAB) Institutional Ownership

13F Institutional Holders and Ownership History from Q1 2017 to Q4 2025

Type / Class
Equity / Common Stock, $0.01 par value
Symbol
ANAB on Nasdaq
Shares outstanding
27,712,115
Price per share
$48.50
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
31,635,003
Total reported value
$968,941,233
% of total 13F portfolios
0%
Share change
-5,117,366
Value change
-$154,408,495
Number of holders
164
Price from insider filings
$48.50
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of ANAPTYSBIO, INC - Common Stock, $0.01 par value (ANAB) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Point72 Asset Management, L.P. 7.7% +35% $49,025,259 +$14,013,859 2,368,370 +40% Point72 Asset Management, L.P. 31 Mar 2025
BlackRock, Inc. 6.2% -28% $39,347,471 -$13,405,817 1,900,844 -25% BlackRock, Inc. 31 Mar 2025
MORGAN STANLEY 6.3% $48,136,102 1,845,002 Morgan Stanley 30 Jun 2025
VANGUARD GROUP INC 5.2% +5.8% $34,133,610 +$448,995 1,537,550 +1.3% The Vanguard Group 30 Jun 2025
MILLENNIUM MANAGEMENT LLC 5.1% $28,851,776 1,426,893 Millennium Management LLC 16 Sep 2025
GOLDMAN SACHS GROUP INC 4.5% -14% $38,314,646 -$10,329,933 1,251,295 -21% THE GOLDMAN SACHS GROUP, INC. 30 Sep 2025
First Light Asset Management, LLC 3.1% -57% $26,474,603 -$42,907,347 864,618 -62% Mathew P. Arens 30 Sep 2025
FMR LLC 0.9% -88% $5,091,861 -$33,068,368 254,212 -87% FMR LLC 30 May 2025

As of 30 Sep 2025, 164 institutional investors reported holding 31,635,003 shares of ANAPTYSBIO, INC - Common Stock, $0.01 par value (ANAB). This represents 114% of the company’s total 27,712,115 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of ANAPTYSBIO, INC - Common Stock, $0.01 par value (ANAB) together control 98% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
EcoR1 Capital, LLC 28% 7,880,094 0% 12% $241,288,478
Point72 Asset Management, L.P. 8.2% 2,265,528 -8.5% 0.15% $69,370,467
BlackRock, Inc. 6.2% 1,722,324 -3.6% 0% $52,737,560
MORGAN STANLEY 5.6% 1,556,258 -17% 0% $47,652,620
MILLENNIUM MANAGEMENT LLC 5.5% 1,519,230 +646% 0.04% $46,518,823
VANGUARD GROUP INC 5.3% 1,476,989 -3.9% 0% $45,225,403
TANG CAPITAL MANAGEMENT LLC 4.8% 1,333,639 +0.21% 1.6% $40,836,026
First Light Asset Management, LLC 3.6% 990,161 -72% 2.9% $30,318,730
STATE STREET CORP 3.2% 873,432 +6.4% 0% $26,744,488
Assenagon Asset Management S.A. 3% 839,934 +4853% 0.04% $25,718,779
Sanofi 3% 821,917 0% 9.7% $25,167,099
Palo Alto Investors LP 2.4% 673,520 -17% 3.8% $20,623,182
Soleus Capital Management, L.P. 2.3% 626,040 +95% 1% $19,169,345
683 Capital Management, LLC 2% 547,000 +9.4% 1.5% $16,749,140
Woodline Partners LP 1.8% 501,023 0% 0.07% $15,341,324
GEODE CAPITAL MANAGEMENT, LLC 1.7% 473,626 +2.2% 0% $14,504,776
JACOBS LEVY EQUITY MANAGEMENT, INC 1.4% 378,452 +2.7% 0.05% $11,588,200
TWO SIGMA ADVISERS, LP 1.3% 373,700 +29% 0.02% $11,442,694
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 1.3% 370,458 +146% 0.01% $11,343,424
D. E. Shaw & Co., Inc. 1.3% 349,360 +211% 0.01% $10,697,403
Nuveen, LLC 1.2% 339,271 +4.9% 0% $10,388,479
GOLDMAN SACHS GROUP INC 1.2% 329,820 +18% 0% $10,099,089
PRICE T ROWE ASSOCIATES INC /MD/ 1.1% 299,311 -56% 0% $9,166,000
TWO SIGMA INVESTMENTS, LP 0.93% 256,420 +11% 0.01% $7,851,580
Sofinnova Investments, Inc. 0.92% 254,268 -75% 0.48% $7,785,686

Institutional Holders of ANAPTYSBIO, INC - Common Stock, $0.01 par value (ANAB) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 11,282 $547,402 -$25,211,082 $48.50 5
2025 Q3 31,635,003 $968,941,233 -$154,408,495 $30.62 164
2025 Q2 36,775,405 $816,417,703 -$61,528,593 $22.20 146
2025 Q1 39,955,702 $742,780,741 +$106,646,664 $18.59 150
2024 Q4 35,417,634 $468,934,603 -$87,874,690 $13.24 133
2024 Q3 33,628,905 $1,126,906,586 +$123,178,333 $33.50 158
2024 Q2 29,795,998 $746,647,480 +$18,365,650 $25.06 133
2024 Q1 29,220,936 $658,049,704 -$20,954,780 $22.52 132
2023 Q4 30,178,929 $646,434,520 +$661,774 $21.42 117
2023 Q3 30,319,401 $544,539,672 -$1,742,551 $17.96 116
2023 Q2 30,230,678 $614,916,059 -$16,322,967 $20.34 116
2023 Q1 31,038,362 $675,357,489 -$44,703,594 $21.76 112
2022 Q4 32,881,839 $1,018,995,107 -$10,549,644 $30.99 114
2022 Q3 32,565,742 $830,751,663 +$39,360,338 $25.51 109
2022 Q2 31,163,975 $632,623,400 +$28,483,649 $20.30 117
2022 Q1 29,681,010 $735,000,699 +$13,953,506 $24.74 124
2021 Q4 27,753,009 $964,436,533 +$8,862,117 $34.75 132
2021 Q3 27,612,274 $748,805,223 -$4,361,131 $27.12 123
2021 Q2 27,792,119 $720,641,941 -$34,119,008 $25.93 117
2021 Q1 29,170,513 $628,617,724 +$26,204,184 $21.55 116
2020 Q4 27,945,751 $600,836,464 -$16,682,226 $21.50 129
2020 Q3 29,118,815 $429,506,449 -$16,534,668 $14.75 127
2020 Q2 29,995,726 $670,116,259 -$17,219,808 $22.34 117
2020 Q1 31,226,700 $441,231,854 +$44,124,506 $14.13 112
2019 Q4 28,278,193 $459,515,291 -$210,904,567 $16.25 119
2019 Q3 29,041,948 $1,016,180,867 -$48,935,396 $34.99 118
2019 Q2 30,188,598 $1,703,071,412 +$118,485,533 $56.42 126
2019 Q1 29,116,728 $2,126,815,017 +$19,403,624 $73.05 128
2018 Q4 28,960,221 $1,847,302,433 -$11,161,189 $63.79 120
2018 Q3 28,571,805 $2,850,575,697 +$379,454,311 $99.77 127
2018 Q2 24,854,220 $1,765,626,873 +$925,670 $71.04 121
2018 Q1 24,343,157 $2,533,621,510 +$62,752,765 $104.08 134
2017 Q4 23,775,515 $2,394,657,180 +$692,566,246 $100.72 116
2017 Q3 17,730,856 $619,647,150 +$143,400,869 $34.95 70
2017 Q2 13,703,868 $327,947,635 -$2,477,474 $23.93 51
2017 Q1 13,764,320 $381,565,000 +$374,641,000 $27.75 48