Magda Marquet - 15 Jan 2026 Form 4 Insider Report for ANAPTYSBIO, INC (ANAB)

Role: Director
Signature: /s/ Eric Loumeau, Attorney-in-Fact
Issuer symbol: ANAB
Transactions as of: 15 Jan 2026
Net transactions value: -$243,321
Form type: 4
Filing time: 16 Jan 2026, 13:05:05 UTC
Previous filing: 08 Jan 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Marquet Magda	Director	C/O ANAPTYSBIO, INC., 10770 WATERIDGE CIRCLE, SUITE 210, SAN DIEGO	/s/ Eric Loumeau, Attorney-in-Fact	16 Jan 2026	0001631486

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ANAB	Common Stock	Options Exercise	$287,210	+11,000	+111%	$26.11	20,930	15 Jan 2026	Direct
transaction	ANAB	Common Stock	Sale	$446,999	-9,290	-44%	$48.12	11,640	15 Jan 2026	Direct	F1
transaction	ANAB	Common Stock	Sale	$83,532	-1,710	-15%	$48.85	9,930	15 Jan 2026	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ANAB	Stock Option (right to buy)	Options Exercise	$0	-11,000	-100%	$0.000000	0	15 Jan 2026	Common Stock	11,000	$26.11	Direct	F3, F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $47.595 to $48.54 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F2	The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $48.625 to $48.88 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3	The stock option is fully vested.
F4	In addition to the options to purchase shares of common stock as set forth in Table II, the Reporting Person also holds additional options to purchase up to an aggregate of 70,104 shares of common stock, which options vest according to their terms.