Comparable stake leader
Fairmount Funds Management LLC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0000907654.
Comparable stake leader
Fairmount Funds Management LLC
Disclosed value leader
Fairmount Funds Management LLC
Comparable rows
50/50
Latest evidence
01 Jul 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC |
13D/G
3/4/5
13F
Harwin Peter Evan · Director, 10%+ Owner · Company
|
20%
|
$997,807,627
14,572,917 shares
|
+$62,159,599 | 01 Jul 2026 |
| Venrock Healthcare Capital Partners III, L.P. |
13D/G
3/4/5
10%+ Owner
|
7.4%
|
$384,606,749
4,556,952 shares
|
-$29,765,095 | 30 Jun 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
6.6%
from 13D/G
|
$474,915,526
4,990,181 shares
|
— | 30 Jun 2026 |
| Capital World Investors |
13F
13D/G
Company
|
5.6%
from 13D/G
|
$323,733,984
3,401,639 shares
|
— | 30 Jun 2026 |
| RTW INVESTMENTS, LP |
13F
13D/G
Company
|
5.2%
from 13D/G
|
$298,741,485
3,139,030 shares
|
— | 30 Jun 2026 |
| Deep Track Capital, LP |
13F
13D/G
Company
|
4.5%
from 13D/G
|
$183,297,420
1,926,000 shares
|
— | 30 Jun 2026 |
| VIKING GLOBAL INVESTORS LP |
13F
13D/G
Company
|
2.5%
from 13D/G
|
$143,086,001
1,503,478 shares
|
— | 30 Jun 2026 |
| FMR LLC |
13F
Company
|
15%
|
$862,016,075
9,057,645 shares
|
— | 30 Jun 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$1,530,537,388.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 17,951,040 | $0 | $1,517,751,670 | -$1,517,751,670 |
| 3-6 | 0 | 189,847 | $0 | $11,583,545 | -$11,583,545 |
| 6-9 | 0 | 39,000 | $0 | $1,202,173 | -$1,202,173 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Showing 1-20 of 31 reporting-owner rows connected to Oruka Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Fairmount Healthcare Fund II L.P. | Director, 10%+ Owner | $221,791,633 | -$300,014,406 | -57% | Mixed | 01 Jul 2026 |
| Fairmount Funds Management LLC | Director, 10%+ Owner | $221,791,633 | -$300,014,406 | -57% | Mixed | 01 Jul 2026 |
| Tomas Kiselak | Director, 10%+ Owner | $221,791,633 | -$300,014,406 | -57% | Mixed | 01 Jul 2026 |
| Fairmount Healthcare Co-Invest III L.P. | Director, 10%+ Owner | $221,791,633 | -$300,014,406 | -57% | Mixed | 01 Jul 2026 |
| Peter Evan Harwin | Director, 10%+ Owner | $221,791,633 | -$300,014,406 | -57% | Mixed | 01 Jul 2026 |
| Lawrence Otto Klein | Chief Executive Officer, Director | $85,556,635 | -$7,079,386 | -7.6% | Filing P/S | 01 Sep 2026 |
| Venrock Healthcare Capital Partners III, L.P. | 10%+ Owner | $47,458,016 | Filing P/S | 10 Feb 2025 | ||
| Funicular Funds, LP | Other*, 10%+ Owner | $22,903,390 | Mixed | 15 Dec 2022 | ||
| Laura Lee Sandler | Chief Operating Officer | $21,750,495 | -$1,855,775 | -7.9% | Filing P/S | 01 Sep 2026 |
| Larry Todd Edwards | Chief Commercial Officer | $9,517,000 | Median | 24 Aug 2026 | ||
| Funicular Fund, LP | Other* | $6,451,130 | Mixed | 23 May 2022 | ||
| Janus Henderson Group Ltd. | 10%+ Owner | $6,302,520 | Filing P/S | 16 Aug 2024 | ||
| Joana Goncalves | Chief Medical Officer | $3,682,810 | -$3,809,307 | -51% | Filing P/S | 17 Aug 2026 |
| Quinlan Paul T. | General Counsel | $3,449,050 | -$5,722,765 | -62% | Filing P/S | 14 Aug 2026 |
| Carl Dambkowski | Director | $2,716,232 | -$8,645,748 | -76% | Filing P/S | 11 Jun 2026 |
| Arjun Agarwal | Senior Vice President, Finance | $1,660,782 | -$3,352,376 | -67% | Filing P/S | 13 Aug 2026 |
| Cameron Turtle | Director | $253,722 | Mixed | 02 Jun 2025 | ||
| Christopher David Ozeroff | S.V.P., General Counsel | $127,425 | Mixed | 14 Dec 2021 | ||
| Robert E. Conway | Director, Chairman of the Board | $125,000 | Mixed | 30 Jan 2024 | ||
| Thomas A. Keuer | Chief Operating Officer | $101,825 | Mixed | 08 Dec 2022 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Laura Lee Sandler | ORKA | Common Stock | Sale | -2.07% | $459,101 | $91.82 | -5,000 | 236,384 | 01 Sep 2026 | Direct |
| Laura Lee Sandler | ORKA | Common Stock | Options Exercise | 2.12% | 5,000 | 241,384 | 01 Sep 2026 | Direct | ||
| Laura Lee Sandler | ORKA | Employee Warrant (right to buy) | Options Exercise | -6.25% | -5,000 | 74,996 | 01 Sep 2026 | Direct | ||
| Lawrence Otto Klein | ORKA | Common Stock | Sale | -7.5% | $6,887,484 | $91.83 | -75,000 | 925,580 | 01 Sep 2026 | Direct |
| Lawrence Otto Klein | ORKA | Common Stock | Options Exercise | 8.1% | 75,000 | 1,000,580 | 01 Sep 2026 | Direct | ||
| Lawrence Otto Klein | ORKA | Employee Warrant (right to buy) | Options Exercise | -4.61% | -75,000 | 1,553,513 | 01 Sep 2026 | Direct | ||
| Larry Todd Edwards | ORKA | Common Stock | Award | 100,000 | 100,000 | 24 Aug 2026 | Direct | |||
| Larry Todd Edwards | ORKA | Employee Stock Option (right to buy) | Award | 20,000 | 20,000 | 24 Aug 2026 | Direct | |||
| Joana Goncalves | ORKA | Common Stock | Sale | -17.6% | $782,882 | $111.84 | -7,000 | 32,718 | 17 Aug 2026 | Direct |
| Joana Goncalves | ORKA | Common Stock | Options Exercise | 21.4% | 7,000 | 39,718 | 17 Aug 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Warrant (right to buy) | Options Exercise | -2.03% | -3,500 | 168,492 | 17 Aug 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Stock Option (right to buy) | Options Exercise | -1.75% | -3,500 | 197,063 | 17 Aug 2026 | Direct | ||
| Quinlan Paul T. | ORKA | Common Stock | Sale | -62.6% | $5,641,409 | $108.49 | -52,000 | 31,034 | 14 Aug 2026 | Direct |
| Quinlan Paul T. | ORKA | Common Stock | Options Exercise | 167.6% | 52,000 | 83,034 | 14 Aug 2026 | Direct | ||
| Quinlan Paul T. | ORKA | Employee Stock Option (right to buy) | Options Exercise | -25.8% | -42,000 | 120,500 | 14 Aug 2026 | Direct | ||
| Quinlan Paul T. | ORKA | Employee Warrant (right to buy) | Options Exercise | -10% | -10,000 | 89,996 | 14 Aug 2026 | Direct | ||
| Arjun Agarwal | ORKA | Common Stock | Sale | -39.5% | $1,066,572 | $106.66 | -10,000 | 15,312 | 13 Aug 2026 | Direct |
| Arjun Agarwal | ORKA | Common Stock | Options Exercise | 65.3% | 10,000 | 25,312 | 13 Aug 2026 | Direct | ||
| Arjun Agarwal | ORKA | Employee Stock Option (right to buy) | Options Exercise | -14.3% | -10,000 | 59,792 | 13 Aug 2026 | Direct | ||
| Joana Goncalves | ORKA | Common Stock | Sale | -17.6% | $603,938 | $86.28 | -7,000 | 32,718 | 15 Jul 2026 | Direct |
| Joana Goncalves | ORKA | Common Stock | Options Exercise | 21.4% | 7,000 | 39,718 | 15 Jul 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Warrant (right to buy) | Options Exercise | -1.99% | -3,500 | 171,992 | 15 Jul 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Stock Option (right to buy) | Options Exercise | -1.72% | -3,500 | 200,563 | 15 Jul 2026 | Direct | ||
| Arjun Agarwal | ORKA | Common Stock | Sale | -39.5% | $846,180 | $84.63 | -9,999 | 15,312 | 13 Jul 2026 | Direct |
| Arjun Agarwal | ORKA | Common Stock | Options Exercise | 65.3% | 9,999 | 25,311 | 13 Jul 2026 | Direct | ||
| Arjun Agarwal | ORKA | Employee Stock Option (right to buy) | Options Exercise | -14% | -9,999 | 61,250 | 13 Jul 2026 | Direct | ||
| Fairmount Funds Management LLC | ORKA | Common Stock | Sale | -75.8% | $300,014,406 | $84.43 | -3,553,410 | 1,131,954 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. |
| Fairmount Funds Management LLC | ORKA | Common Stock | Sale | -75.8% | $300,014,406 | $84.43 | -3,553,410 | 1,131,954 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. |
| Fairmount Funds Management LLC | ORKA | Common Stock | Sale | -75.8% | $300,014,406 | $84.43 | -3,553,410 | 1,131,954 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. |
| Fairmount Funds Management LLC | ORKA | Common Stock | Sale | -75.8% | $300,014,406 | $84.43 | -3,553,410 | 1,131,954 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. |
| Fairmount Funds Management LLC | ORKA | Common Stock | Sale | -75.8% | $300,014,406 | $84.43 | -3,553,410 | 1,131,954 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. |
| Fairmount Funds Management LLC | ORKA | Common Stock | Conversion of derivative security | 313.9% | 3,553,410 | 4,685,364 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Common Stock | Conversion of derivative security | 313.9% | 3,553,410 | 4,685,364 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Common Stock | Conversion of derivative security | 313.9% | 3,553,410 | 4,685,364 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Common Stock | Conversion of derivative security | 313.9% | 3,553,410 | 4,685,364 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Common Stock | Conversion of derivative security | 313.9% | 3,553,410 | 4,685,364 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Series B Preferred Stock | Conversion of derivative security | -31.1% | -42,641 | 94,497 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Series B Preferred Stock | Conversion of derivative security | -31.1% | -42,641 | 94,497 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Series B Preferred Stock | Conversion of derivative security | -31.1% | -42,641 | 94,497 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Series B Preferred Stock | Conversion of derivative security | -31.1% | -42,641 | 94,497 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Fairmount Funds Management LLC | ORKA | Series B Preferred Stock | Conversion of derivative security | -31.1% | -42,641 | 94,497 | 01 Jul 2026 | By Fairmount Healthcare Fund II L.P. | ||
| Laura Lee Sandler | ORKA | Common Stock | Sale | -2.07% | $472,079 | $94.42 | -5,000 | 236,384 | 01 Jul 2026 | Direct |
| Laura Lee Sandler | ORKA | Common Stock | Options Exercise | 2.12% | 5,000 | 241,384 | 01 Jul 2026 | Direct | ||
| Laura Lee Sandler | ORKA | Employee Warrant (right to buy) | Options Exercise | -5.88% | -5,000 | 79,996 | 01 Jul 2026 | Direct | ||
| Arjun Agarwal | ORKA | Common Stock | Sale | -9.39% | $128,468 | $80.95 | -1,587 | 15,312 | 22 Jun 2026 | Direct |
| Arjun Agarwal | ORKA | Common Stock | Sale | -2.28% | $27,528 | $69.69 | -395 | 16,899 | 15 Jun 2026 | Direct |
| Joana Goncalves | ORKA | Common Stock | Sale | -19.5% | $550,607 | $69.28 | -7,947 | 32,718 | 15 Jun 2026 | Direct |
| Joana Goncalves | ORKA | Common Stock | Options Exercise | 20.8% | 7,000 | 40,665 | 15 Jun 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Warrant (right to buy) | Options Exercise | -1.96% | -3,500 | 175,492 | 15 Jun 2026 | Direct | ||
| Joana Goncalves | ORKA | Employee Stock Option (right to buy) | Options Exercise | -1.69% | -3,500 | 204,063 | 15 Jun 2026 | Direct |