SEC ownership of BIOCRYST PHARMACEUTICALS INC

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0000882796.

Comparable stake leader

BlackRock, Inc.

Disclosed value leader

BlackRock, Inc.

Comparable rows

50/50

Latest evidence

30 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
BlackRock, Inc.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0000882796
Issuer location
Durham, NC

Ownership snapshot

Top shareholders of BIOCRYST PHARMACEUTICALS INC (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
BlackRock, Inc.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
30 Jun 2026
13F 13D/G 3/4/5 Lead comparable stake: 8.4% 13D/G row: BlackRock, Inc. Showing 1-8 of 50 holder rows.

Quick read

BlackRock, Inc. leads the comparable SEC ownership view at 8.4%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BlackRock, Inc.'s linked filing trail.
Comparable ownership Top 5
BlackRock, Inc. 8.4%
James E. Flynn 6.8%
RA CAPITAL MANAGEMENT, L.P. 6.2%
STATE STREET CORP 6%
VANGUARD CAPITAL MANAGEMENT LLC 5.2%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
BlackRock, Inc.
13F 13D/G
Company
8.4%
from 13D/G
$238,930,360
23,893,036 shares
30 Jun 2026
James E. Flynn
13D/G
Deerfield Mgmt, L.P.
6.8%
$109,278,420
14,341,000 shares
+$16,550,640 31 Dec 2025
RA CAPITAL MANAGEMENT, L.P.
13D/G 13F
Company
6.2%
$173,940,774
15,827,186 shares
+$5,769,750 30 Jun 2026
STATE STREET CORP
13D/G 13F
STATE STREET CORPORATION · Company
6%
$166,950,167
15,191,098 shares
+$32,780,291 30 Jun 2026
VANGUARD CAPITAL MANAGEMENT LLC
13D/G 13F
Vanguard Capital Management · Company
5.2%
$123,390,357
12,961,172 shares
$0 31 Mar 2026
Avoro Capital Advisors LLC
13D/G
4.2%
$71,514,000
8,700,000 shares
$0 31 Mar 2025
Charles K. Gayer
3/4/5
President and CCO
0.37%
$5,248,732
952,583 shares
19 Dec 2025
Alane P. Barnes
3/4/5
Chief Legal Officer
0.16%
$3,822,706
400,703 shares
-$3,462,537 13 May 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$4,136,188.

Buys
$0
Insiders: 0
Sells
$4,136,188
Insiders: 4
Net
-$4,136,188
Shares: -487,876
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 487,876
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 273,613 $0 $2,573,857 -$2,573,857
6-9 0 42,983 $0 $328,820 -$328,820
9-12 0 171,280 $0 $1,233,511 -$1,233,511

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 24 reporting-owner rows connected to BIOCRYST PHARMACEUTICALS INC. Open a relationship link for the CIK-to-CIK filing trail.

Rows
24
Largest Forms 3/4/5 holder
Jon P. Stonehouse
Net 12M change
-$4,136,189
Latest report
31 Aug 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Jon P. Stonehouse Director $14,204,190 Median 31 Aug 2026
Charles K. Gayer President and CCO $5,248,732 Mixed 19 Dec 2025
Alane P. Barnes Chief Legal Officer $3,822,706 -$3,462,537 -48% Filing P/S 13 May 2026
Helen M. Thackray Chief R&D Officer $2,829,885 Mixed 31 Mar 2025
Anthony Doyle Chief Financial Officer $2,792,437 Mixed 19 Dec 2024
Ronald Dullinger Chief Commercial Officer $2,015,146 Mixed 01 Jan 2026
Sandeep Menon Chief R&D Officer $1,953,069 Mixed 06 Apr 2026
Babar Ghias Chief Financial Officer $1,862,091 Mixed 17 Dec 2025
Yarlagadda S. Babu Chief Discovery Officer $1,806,173 Mixed 14 Nov 2022
Vincent Milano Director $1,096,420 Median 31 Aug 2026
Nancy J. Hutson Director $1,025,086 Mixed 12 Jun 2025
Steven K. Galson Director $820,289 Mixed 11 Jun 2026
Theresa Heggie Director $767,749 -$504,823 -40% Mixed 11 Jun 2026
Alan G. Levin Director $757,458 Mixed 11 Jun 2026
Robert Alexander Ingram Director $606,198 Mixed 28 Feb 2023
Amy E. McKee Director $478,210 -$100,285 -17% Median 31 Aug 2026
Steve Aselage Director $469,377 Mixed 12 Jun 2024
Machelle Sanders Director $437,310 -$68,544 -14% Mixed 11 Jun 2026
Kenneth B. Lee Jr. Director $416,621 Mixed 13 Jun 2023
Steven Frank Director $367,470 Median 31 Aug 2026

Recent insider transactions for BIOCRYST PHARMACEUTICALS INC

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Jon P. Stonehouse BCRX Common Stock Award 0.05% 644 1,340,419 31 Aug 2026 Direct
Vincent Milano BCRX Common Stock Award 1.07% 1,159 109,642 31 Aug 2026 Direct
Jill C. Milne BCRX Common Stock Award 4.03% 1,288 33,226 31 Aug 2026 Direct
Amy E. McKee BCRX Common Stock Award 1.37% 644 47,821 31 Aug 2026 Direct
Steven Frank BCRX Common Stock Award 3.63% 1,288 36,747 31 Aug 2026 Direct
Jill C. Milne BCRX Common Stock Award 91.9% 15,294 31,938 11 Jun 2026 Direct
Jill C. Milne BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Steven K. Galson BCRX Common Stock Award 122.4% 15,294 27,794 11 Jun 2026 Direct
Steven K. Galson BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Alan G. Levin BCRX Common Stock Award 23.8% 15,294 79,565 11 Jun 2026 Direct
Alan G. Levin BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Steven Frank BCRX Common Stock Award 75.8% 15,294 35,459 11 Jun 2026 Direct
Steven Frank BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Machelle Sanders BCRX Common Stock Award 49.9% 15,294 45,936 11 Jun 2026 Direct
Machelle Sanders BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Vincent Milano BCRX Common Stock Award 16.4% 15,294 108,483 11 Jun 2026 Direct
Vincent Milano BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Jon P. Stonehouse BCRX Common Stock Award 1.15% 15,294 1,339,775 11 Jun 2026 Direct
Jon P. Stonehouse BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Amy E. McKee BCRX Common Stock Award 48% 15,294 47,177 11 Jun 2026 Direct
Amy E. McKee BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Theresa Heggie BCRX Common Stock Award 23.4% 15,294 80,646 11 Jun 2026 Direct
Theresa Heggie BCRX Automatic Stock Option Grant Award 33,540 33,540 11 Jun 2026 Direct
Jill C. Milne BCRX Common Stock Award 8.2% 1,262 16,644 29 May 2026 Direct
Jon P. Stonehouse BCRX Common Stock Award 0.05% 631 1,324,481 29 May 2026 Direct
Amy E. McKee BCRX Common Stock Award 2.02% 631 31,883 29 May 2026 Direct
Vincent Milano BCRX Common Stock Award 1.22% 1,122 93,189 29 May 2026 Direct
Steven Frank BCRX Common Stock Award 6.68% 1,262 20,165 29 May 2026 Direct
Amy E. McKee BCRX Common Stock Sale -26.4% $100,285 $8.97 -11,180 31,252 18 May 2026 Direct
Alane P. Barnes BCRX Common Stock Sale -13.5% $596,250 $9.54 -62,500 400,703 13 May 2026 Direct
Alane P. Barnes BCRX Common Stock Options Exercise 15.6% 62,500 463,203 13 May 2026 Direct
Alane P. Barnes BCRX Emp. Stock Option (Right to Buy) Options Exercise -100% -62,500 0 13 May 2026 Direct
Sandeep Menon BCRX Common Stock Award 205,150 205,150 06 Apr 2026 Direct
Sandeep Menon BCRX Emp. Stock Option (Right to Buy) Award 441,350 441,350 06 Apr 2026 Direct
Theresa Heggie BCRX Common Stock Sale -43.3% $504,823 $10.11 -49,933 65,352 20 Mar 2026 Direct
Theresa Heggie BCRX Common Stock Options Exercise 76.4% 49,933 115,285 20 Mar 2026 Direct
Theresa Heggie BCRX Automatic Stock Option Grant Options Exercise -100% -49,933 0 20 Mar 2026 Direct
Alane P. Barnes BCRX Common Stock Sale -27.2% $1,372,500 $9.15 -150,000 400,703 16 Mar 2026 Direct
Alane P. Barnes BCRX Common Stock Options Exercise 37.4% 150,000 550,703 16 Mar 2026 Direct
Alane P. Barnes BCRX Emp. Stock Option (Right to Buy) Options Exercise -100% -150,000 0 16 Mar 2026 Direct
Jon P. Stonehouse BCRX Common Stock Disposed to Issuer -18.8% -305,995 1,323,850 02 Mar 2026 Direct
Jon P. Stonehouse BCRX Common Stock Options Exercise 23.1% 305,995 1,629,845 02 Mar 2026 Direct
Jon P. Stonehouse BCRX Emp. Stock Option (Right to Buy) Options Exercise -100% -305,995 0 02 Mar 2026 Direct
Jill C. Milne BCRX Common Stock Award 3.55% 528 15,382 27 Feb 2026 Direct
Jon P. Stonehouse BCRX Common Stock Award 0.03% 421 1,323,850 27 Feb 2026 Direct
Vincent Milano BCRX Common Stock Award 0.93% 848 92,067 27 Feb 2026 Direct
Steven Frank BCRX Common Stock Award 7.29% 1,285 18,903 27 Feb 2026 Direct
Amy E. McKee BCRX Common Stock Award 1.54% 642 42,432 27 Feb 2026 Direct
Jill C. Milne BCRX Common Stock Award 14,854 14,854 23 Jan 2026 Direct
Jill C. Milne BCRX Automatic Stock Option Grant Award 26,684 26,684 23 Jan 2026 Direct
* marks a reported price that did not pass the local price check.
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