Security Snapshot

BIOCRYST PHARMACEUTICALS INC - COMMON STOCK (BCRX) Institutional Ownership

CUSIP: 09058V103

13F Institutional Holders and Ownership History from Q1 2014 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

298

Shares (Excl. Options)

247,442,463

Price

$9.52

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Type / Class
Equity / COMMON STOCK
Symbol
BCRX on Nasdaq
Shares outstanding
249,150,204
Price per share
$8.99
All holders as of 31 Mar 2026
Q1 2026
Total 13F shares
247,442,463
Total reported value
$2,355,312,270
% of total 13F portfolios
0%
Share change
+34,253,562
Value change
+$351,468,980
Number of holders
298
Price from insider filings
$8.99
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Key facts

  • BCRX - BIOCRYST PHARMACEUTICALS INC - COMMON STOCK is tracked under CUSIP 09058V103.
  • 298 institutions reported positions in Q1 2026.
  • 6 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 274 to 298 between Q4 2025 and Q1 2026.
  • Reported value moved from $1,657,283,429 to $2,355,312,270.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 298 institutions filings for Q1 2026.

Open SEC Evidence

Security key

09058V103

Latest holder period

Q1 2026

13F holders

298

13D/G owners

6

CIK / CUSIP context first

Significant Owners of BIOCRYST PHARMACEUTICALS INC - COMMON STOCK (BCRX) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
BlackRock, Inc. 8.4% $143,714,288 17,483,490 BlackRock, Inc. 31 Mar 2025
RA CAPITAL MANAGEMENT, L.P. 7.3% $116,143,592 15,302,186 RA Capital Management, L.P. 04 Nov 2025
Flynn James E 6.8% +17% $109,278,420 +$16,550,640 14,341,000 +18% Deerfield Mgmt, L.P. 31 Dec 2025
VANGUARD CAPITAL MANAGEMENT LLC 5.2% $123,390,357 12,961,172 Vanguard Capital Management 31 Mar 2026
STATE STREET CORP 4.9% -8% $114,880,668 +$10,681,752 12,208,360 +10% STATE STREET CORPORATION 31 Mar 2026
Avoro Capital Advisors LLC 4.2% $71,514,000 8,700,000 Avoro Capital Advisors LLC 31 Mar 2025

As of 31 Mar 2026, 298 institutional investors reported holding 247,442,463 shares of BIOCRYST PHARMACEUTICALS INC - COMMON STOCK (BCRX). This represents 99% of the company’s total 249,150,204 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of BIOCRYST PHARMACEUTICALS INC - COMMON STOCK (BCRX) together control 74% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
BlackRock, Inc. 9.1% 22,650,988 +7.2% 0% $215,637,401
RA CAPITAL MANAGEMENT, L.P. 6.4% 15,827,186 0% 1.6% $150,674,811
DEERFIELD MANAGEMENT COMPANY, L.P. 6% 15,038,000 +4.9% 1.7% $143,161,760
STATE STREET CORP 4.9% 12,208,360 +10% 0% $116,223,587
VANGUARD PORTFOLIO MANAGEMENT LLC 4.5% 11,244,625 0% 0.01% $107,048,830
VANGUARD CAPITAL MANAGEMENT LLC 4.5% 11,135,762 0% 0% $106,012,454
TCG Crossover Management, LLC 4.4% 11,020,968 3% $104,919,615
JANUS HENDERSON GROUP PLC 3.6% 8,908,506 +20% 0.04% $84,853,520
PERCEPTIVE ADVISORS LLC 3% 7,434,033 +135% 1.4% $70,771,994
Vestal Point Capital, LP 2.8% 7,025,000 +212% 1.9% $66,878,000
TWO SIGMA INVESTMENTS, LP 2.6% 6,392,628 +42% 0.05% $60,857,819
GEODE CAPITAL MANAGEMENT, LLC 2.3% 5,782,776 +14% 0% $55,063,276
Kynam Capital Management, LP 2.3% 5,680,795 -39% 3.4% $54,081,168
BANK OF AMERICA CORP /DE/ 2% 5,091,765 +232% 0% $48,473,603
Aberdeen Group plc 2% 5,040,670 +452% 0.08% $47,987,178
UBS Group AG 2% 4,943,994 -6.1% 0.01% $47,066,823
Frazier Life Sciences Management, L.P. 1.6% 4,009,240 0.98% $38,167,965
Royalty Pharma Sub-Manager, LLC 1.5% 3,846,154 0% 21% $36,615,386
Nuveen, LLC 1.5% 3,819,263 +5.7% 0.01% $36,359,384
GW&K Investment Management, LLC 1.3% 3,240,462 +2.5% 0.27% $30,850,000
Eversept Partners, LP 1.2% 3,039,820 +1.6% 1.9% $28,939,086
RFG Advisory, LLC 1.2% 2,870,700 0.5% $27,329,064
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.1% 2,815,304 +319% 0.03% $26,801,694
Fisher Asset Management, LLC 1.1% 2,733,253 +11% 0.01% $26,020,567
DIMENSIONAL FUND ADVISORS LP 1.1% 2,690,651 +119% 0.01% $25,614,944

Institutional Holders of BIOCRYST PHARMACEUTICALS INC - COMMON STOCK (BCRX) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 247,442,463 $2,355,312,270 +$351,468,980 $9.52 298
2025 Q4 212,542,303 $1,657,283,429 +$104,832,674 $7.80 274
2025 Q3 194,102,191 $1,473,118,671 -$35,936,486 $7.59 282
2025 Q2 197,129,798 $1,766,723,682 +$203,493,373 $8.96 292
2025 Q1 174,435,511 $1,308,746,834 +$63,398,447 $7.50 273
2024 Q4 167,662,220 $1,261,171,584 -$40,361,715 $7.52 256
2024 Q3 173,102,982 $1,315,577,234 -$13,496,556 $7.60 255
2024 Q2 174,343,886 $1,077,260,403 -$26,171,848 $6.18 238
2024 Q1 179,854,267 $913,665,406 +$14,530,963 $5.08 235
2023 Q4 176,879,832 $1,059,530,995 -$13,874,803 $5.99 234
2023 Q3 175,748,697 $1,244,274,073 +$20,781,164 $7.08 229
2023 Q2 174,092,743 $1,225,943,210 +$15,794,543 $7.04 233
2023 Q1 170,682,621 $1,423,483,184 +$98,954,044 $8.34 237
2022 Q4 157,670,070 $1,809,819,957 +$89,114,288 $11.48 225
2022 Q3 149,200,472 $1,879,908,994 -$39,491,355 $12.60 218
2022 Q2 151,882,406 $1,606,941,793 +$202,016,904 $10.58 207
2022 Q1 127,644,333 $2,074,127,946 +$162,394,498 $16.26 219
2021 Q4 118,034,837 $1,624,605,826 +$189,498,647 $13.85 197
2021 Q3 103,285,294 $1,484,281,647 -$23,674,937 $14.37 191
2021 Q2 104,615,646 $1,653,902,810 +$25,597,252 $15.81 190
2021 Q1 104,536,942 $1,063,154,138 -$141,911,795 $10.17 183
2020 Q4 120,536,116 $897,922,105 -$43,570,187 $7.45 172
2020 Q3 127,504,811 $438,191,012 -$23,494,376 $3.44 150
2020 Q2 133,168,915 $634,861,180 +$96,615,986 $4.76 160
2020 Q1 122,545,605 $245,076,906 -$37,929,778 $2.00 127
2019 Q4 137,257,236 $473,298,973 +$126,158,746 $3.45 131
2019 Q3 98,732,839 $282,887,178 -$6,967,337 $2.86 110
2019 Q2 100,189,285 $379,651,222 -$87,862,478 $3.79 112
2019 Q1 101,459,192 $825,845,210 +$1,493,806 $8.14 129
2018 Q4 101,241,798 $817,039,643 +$8,890,495 $8.07 118
2018 Q3 100,143,382 $764,063,804 +$73,654,467 $7.63 110
2018 Q2 87,486,065 $501,300,833 -$8,812,924 $5.73 98
2018 Q1 89,084,172 $424,940,474 -$6,631,982 $4.77 98
2017 Q4 90,315,627 $443,489,038 +$30,241,042 $4.91 111
2017 Q3 83,706,610 $438,584,580 +$76,310,817 $5.24 118
2017 Q2 69,068,637 $384,022,057 +$3,627,924 $5.56 112
2017 Q1 67,625,892 $568,043,111 +$140,009,973 $8.40 114
2016 Q4 58,390,925 $369,592,679 +$11,848,602 $6.33 107
2016 Q3 56,560,503 $249,434,126 +$23,437,473 $4.41 98
2016 Q2 51,754,204 $146,980,142 -$10,557,522 $2.84 91
2016 Q1 55,499,247 $157,041,490 -$57,851,659 $2.83 103
2015 Q4 63,010,560 $650,239,667 -$21,193,454 $10.32 116
2015 Q3 64,961,257 $740,441,332 +$18,203,435 $11.40 123
2015 Q2 62,979,534 $940,208,410 -$26,293,353 $14.93 121
2015 Q1 64,945,642 $586,470,031 +$36,664,370 $9.03 96
2014 Q4 60,839,929 $739,630,154 +$22,530,982 $12.16 90
2014 Q3 56,671,419 $554,271,573 +$30,624,768 $9.78 101
2014 Q2 53,076,615 $676,805,598 +$130,669,664 $12.75 100
2014 Q1 43,477,699 $460,383,679 +$93,247,685 $10.58 86
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