Opaleye Management Inc. - 12 Dec 2025 SCHEDULE 13G Report for Rezolute, Inc. Common Stock (RZLT)

Filing Manager: Opaleye Management Inc.
Reporting Manager: Opaleye Management Inc.
Security: Rezolute, Inc. Common Stock
Symbol: RZLT
Shares outstanding: 92,696,226 shares
Disclosed Ownership: 4,912,900 shares
Ownership: 5.3%
Form type: SCHEDULE 13G
Filing time: 19 Dec 2025, 16:05:16 UTC
Date of event: 12 Dec 2025
SEC: View on sec.gov

Reporting Managers (3)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
Opaleye Management Inc.	5.3%	4,912,900	0	4,912,900	/s/ James Silverman	President
Opaleye, L.P.	5.16%	4,785,000	0	4,785,000	/s/ James Silverman	General Partner
James Silverman	5.3%	4,912,900	0	4,912,900	/s/ James Silverman	Individually