RTW INVESTMENTS, LP - 30 Jun 2025 SCHEDULE 13G/A Report for TAYSHA GENE THERAPIES, INC. Common Stock, par value $0.00001 per share (TSHA)

Filing Manager: RTW INVESTMENTS, LP
Reporting Manager: RTW Investments, LP
Security: TAYSHA GENE THERAPIES, INC. Common Stock, par value $0.00001 per share
Symbol: TSHA
Shares outstanding: 254,376,636 shares
Disclosed Ownership: 25,183,287 shares
Ownership: 9.9%
Form type: SCHEDULE 13G/A
Filing time: 14 Aug 2025, 08:10:16 UTC
Date of event: 30 Jun 2025
Previous filing: 15 May 2025
SEC: View on sec.gov

Reporting Managers (2)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
RTW Investments, LP	9.9%	25,183,287	0	25,183,287	/s/ Roderick Wong, M.D.	Roderick Wong, M.D., Managing Partner
Roderick Wong	9.9%	25,183,287	0	25,183,287	s/ Roderick Wong, M.D.	Roderick Wong, M.D.