| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 11.3% | 2.3M | 0 | 2.3M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.5% | 1.12M | 0 | 1.12M | Kristin Mariani | Head of North America Compliance, CCO |