| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14.3% | 22.7M | 0 | 22.7M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 12.7% | 20.1M | 0 | 20.1M | Kristin Mariani | Head of North America Compliance, CCO |