Perceptive Advisors Llc - Nov 14, 2025 SCHEDULE 13D/A Report for Lyra Therapeutics, Inc. Common Stock, $0.001 par value (LYRA)

Filing Manager
Perceptive Advisors Llc
Reporting Manager
Perceptive Advisors LLC
Security
Lyra Therapeutics, Inc. Common Stock, $0.001 par value
Symbol
LYRA
Shares outstanding
1.79M shares
Disclosed Ownership
98.3K shares
Ownership
5.5%
Form type
SCHEDULE 13D/A
Date filed
11/18/2025, 04:14 PM
Date of event
Nov 14, 2025
Previous filing
Nov 13, 2025
Next filing
Nov 25, 2025
SEC
View on sec.gov

Reporting Managers (4)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
Perceptive Advisors LLC 5.5% 98.3K 0 98.3K /s/ Joseph Edelman Joseph Edelman, Managing Member 0001224962
Joseph Edelman 5.5% 98.3K 0 98.3K /s/ Joseph Edelman Joseph Edelman 0001164426
Perceptive Life Sciences Master Fund, Ltd. 5% 88.4K 0 88.4K /s/ Joseph Edelman Joseph Edelman, Managing Member 0001249675
Perceptive LS (A), LLC 0.6% 9.93K 0 9.93K Perceptive LS GP, LLC Joseph Edelman, Member 0001797811