Opaleye Management Inc.

Holdings History for AFFIMED N V - COM (AFMD)

Symbol: AFMD on Nasdaq
Investment type: Equity / COM

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
31 Dec 2016		-0.63%	$0	0	-430,000	-100%		Q4 2016
30 Sep 2016	0.63%	-0.24%	$1,195,000	430,000	-165,000	-28%	$2.78	Q3 2016
30 Jun 2016	0.99%	-0.02%	$1,476,000	595,000	-15,000	-2.5%	$2.48	Q2 2016
31 Mar 2016	1.5%	+0.04%	$2,281,000	610,000	+15,000	+2.5%	$3.74	Q1 2016
31 Dec 2015	1.8%	+0.01%	$4,236,000	595,000	+4,700	+0.8%	$7.12	Q4 2015
30 Sep 2015	1.8%	0%	$3,642,000	590,300	0		$6.17	Q3 2015
30 Jun 2015	3.3%	+3.3%	$7,951,000	590,300	+590,300	NEW	$13.47	Q2 2015

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.