Opaleye Management Inc.

Holdings History for Synlogic, Inc. - Common Stock, par value $0.001 (SYBX)

Symbol: SYBX on Nasdaq
Investment type: Equity / Common Stock, par value $0.001

Shares, Excluding Options vs Price

Value, Excluding Options

Holdings date	Weight	Change	Value $	Shares	Change	Activity %	Price	All Holders
30 Jun 2022		-0.73%	$0	0	-984,200	-100%		Q2 2022
31 Mar 2022	0.73%	+0.1%	$2,362,000	984,200	+134,200	+16%	$2.40	Q1 2022
31 Dec 2021	0.44%	+0.44%	$2,057,000	850,000	+850,000	NEW	$2.42	Q4 2021
31 Dec 2017		-1.7%	$0	0	-250,000	-100%		Q4 2017
30 Sep 2017	1.7%	+1.7%	$4,753,000	250,000	+250,000	NEW	$19.01	Q3 2017

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.