| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 6.4% | $71,038,400 | 4,640,000 | $15.31 | 13G/A | 31 Dec 2025 | 17 Feb 2026, 18:24 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 2.3% | -2% | $49,774,525 | 3,251,112 | -2,893,655 | -47% | $15.31 | Q4 2025 | |
| 31 Dec 2025 | call | 7.8% | +7.8% | $1,033,425 | 67,500 | +67,500 | NEW | $15.31 | Q4 2025 |
| 30 Sep 2025 | 3.5% | 0% | $72,078,117 | 6,144,767 | 0 | $11.73 | Q3 2025 | ||
| 30 Jun 2025 | 2.9% | 0% | $48,297,869 | 6,144,767 | 0 | $7.86 | Q2 2025 | ||
| 31 Mar 2025 | 3.9% | 0% | $65,380,321 | 6,144,767 | 0 | $10.64 | Q1 2025 | ||
| 31 Dec 2024 | 5.7% | +0.75% | $141,206,746 | 6,144,767 | +814,351 | +15% | $22.98 | Q4 2024 | |
| 30 Sep 2024 | 3.7% | 0% | $107,194,666 | 5,330,416 | 0 | $20.11 | Q3 2024 | ||
| 30 Jun 2024 | 3.1% | 0% | $100,904,775 | 5,330,416 | 0 | $18.93 | Q2 2024 | ||
| 31 Mar 2024 | 3% | +0.03% | $117,962,106 | 5,330,416 | +47,900 | +0.91% | $22.13 | Q1 2024 | |
| 31 Dec 2023 | 2.9% | 0% | $112,147,815 | 5,282,516 | 0 | $21.23 | Q4 2023 | ||
| 30 Sep 2023 | 3.6% | 0% | $106,442,697 | 5,282,516 | 0 | $20.15 | Q3 2023 | ||
| 30 Jun 2023 | 3.5% | 0% | $131,904,425 | 5,282,516 | 0 | $24.97 | Q2 2023 | ||
| 31 Mar 2023 | 4.7% | 0% | $147,329,371 | 5,282,516 | 0 | $27.89 | Q1 2023 | ||
| 31 Dec 2022 | 4.2% | 0% | $137,556,717 | 5,282,516 | 0 | $26.04 | Q4 2022 | ||
| 30 Sep 2022 | 4.1% | +0% | $137,240,000 | 5,282,516 | +100 | +0% | $25.98 | Q3 2022 | |
| 30 Jun 2022 | 5% | +0.3% | $144,580,000 | 5,282,416 | +313,660 | +6.3% | $27.37 | Q2 2022 | |
| 31 Mar 2022 | 4.2% | +0.05% | $132,566,000 | 4,968,756 | +62,650 | +1.3% | $26.68 | Q1 2022 | |
| 31 Dec 2021 | 6.3% | 0% | $196,833,000 | 4,906,106 | 0 | $40.12 | Q4 2021 | ||
| 30 Sep 2021 | 5.7% | 0% | $160,233,000 | 4,906,106 | 0 | $32.66 | Q3 2021 | ||
| 30 Jun 2021 | 6.4% | +0.01% | $169,212,000 | 4,906,106 | +5,800 | +0.12% | $34.49 | Q2 2021 | |
| 31 Mar 2021 | 9.4% | +0.68% | $211,007,000 | 4,900,306 | +353,234 | +7.8% | $43.06 | Q1 2021 | |
| 31 Dec 2020 | 11% | 0% | $198,389,000 | 4,547,072 | 0 | $43.63 | Q4 2020 | ||
| 30 Sep 2020 | 13% | 0% | $176,381,000 | 4,547,072 | 0 | $38.79 | Q3 2020 | ||
| 30 Jun 2020 | 11% | +5% | $147,280,000 | 4,547,072 | +2,045,515 | +82% | $32.39 | Q2 2020 | |
| 31 Mar 2020 | 7.8% | 0% | $74,747,000 | 2,501,557 | 0 | $29.88 | Q1 2020 | ||
| 31 Dec 2019 | 8.2% | 0% | $86,029,000 | 2,501,557 | 0 | $34.39 | Q4 2019 | ||
| 30 Sep 2019 | 11% | +0.74% | $84,378,000 | 2,501,557 | +165,000 | +7.1% | $33.73 | Q3 2019 | |
| 30 Jun 2019 | 9.9% | +1.2% | $95,635,000 | 2,336,557 | +277,128 | +13% | $40.93 | Q2 2019 | |
| 31 Mar 2019 | 6.9% | +3.6% | $63,966,000 | 2,059,429 | +1,070,411 | +108% | $31.06 | Q1 2019 | |
| 31 Dec 2018 | 4.1% | +4.1% | $35,763,000 | 989,018 | +989,018 | NEW | $36.16 | Q4 2018 | |
| 31 Mar 2018 | -0.33% | $0 | 0 | -112,976 | -100% | $11.62 | Q1 2018 | ||
| 31 Dec 2017 | 0.33% | +0.07% | $2,476,000 | 112,976 | +22,862 | +25% | $21.92 | Q4 2017 | |
| 30 Sep 2017 | 0.28% | +0.28% | $2,065,000 | 90,114 | +90,114 | NEW | $22.92 | Q3 2017 | |
| 30 Jun 2017 | -1.6% | $0 | 0 | -234,813 | -100% | $11.62 | Q2 2017 | ||
| 31 Mar 2017 | 1.6% | -0.93% | $5,617,000 | 234,813 | -140,187 | -37% | $23.92 | Q1 2017 | |
| 31 Dec 2016 | 3.4% | +3.4% | $9,870,000 | 375,000 | +375,000 | NEW | $26.32 | Q4 2016 | |
| 30 Sep 2016 | -1.5% | $0 | 0 | -168,000 | -100% | $11.62 | Q3 2016 | ||
| 30 Jun 2016 | 1.5% | +1.5% | $3,190,000 | 168,000 | +168,000 | NEW | $18.99 | Q2 2016 |