Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value per share (SYRS)

CUSIP: 87184Q206

Q4 2024 13F Holders as of 31 Dec 2024

Holder snapshot 7 signals
Share change
-13,727,537
Put/Call ratio
691%
SEC-reported price per share
$0.23
Number of holders
42
Value change
-$29,973,996
Number of buys
16
Open additional details 1 more signal available
Number of sells
37
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
27,196,692

Security key

87184Q206

Report period

Q4 2024

Institutions

42

Top holders

10

Ownership snapshot

Top reported holders of SYRS - Syros Pharmaceuticals, Inc. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Avidity Partners Manageme...
Disclosed value leader
Bain Capital Life Science...
Comparable rows
15/15
Latest evidence
31 Dec 2024
13F 13D/G Lead comparable stake: 7.6% 13D/G row: Avidity Partners Management LP Showing 1-6 of 15 holder rows.

Quick read

Avidity Partners Management LP leads the comparable SEC ownership view at 7.6%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Avidity Partners Management LP's linked filing trail.
Comparable ownership Top 5
Avidity Partners Management LP 7.6%
Invus Global Management, LLC 3.8%
Samsara BioCapital, L.P. 2.6%
ADAGE CAPITAL PARTNERS GP, L.L.C. 2%
Point72 Asset Management, L.P. 0%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Avidity Partners Management LP
13F 13D/G
Company
7.6%
from 13D/G
$2,285,450
1,063,000 shares
30 Sep 2024
Invus Global Management, LLC
13D/G
Invus Public Equities, L.P.
3.8%
$776,595
1,063,829 shares
$0 31 Dec 2024
Samsara BioCapital, L.P.
13D/G
2.6%
$21,213
707,114 shares
$0 18 Nov 2024
ADAGE CAPITAL PARTNERS GP, L.L.C.
13F 13D/G
Company · Adage Capital Management, L.P.
2%
from 13D/G
$4,454,615
2,071,914 shares
30 Sep 2024
Point72 Asset Management, L.P.
13F 13D/G
Company
0%
from 13D/G
$3,164,308
1,471,771 shares
30 Sep 2024
Bain Capital Life Sciences Investors, LLC
13F
Company
13F
10%
$5,912,825
2,750,151 shares
30 Sep 2024
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2024

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
42
Shares
5,216,797
Rows available
42
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2024 vs Q3 2024 Across Filers

Q3 2024 holders
64
Q4 2024 holders
42
Holder diff
-22
Investor Q3 2024 Shares Q4 2024 Shares Share Diff Share Chg % Q3 2024 value Q4 2024 value Value change Value Chg %
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