Sionna Therapeutics, Inc. - Common Stock SH (SION)

CUSIP: 829401108

Q3 2025 13F Holders as of 30 Sep 2025

Type / Class
Equity / Common Stock SH
Shares outstanding
44,894,622
Total 13F shares
42,840,564
Share change
-608,448
Total reported value
$1,259,943,482
Price per share
$29.41
Number of holders
78
Value change
-$14,718,322
Number of buys
38
Number of sells
25

Quarterly Holders Quick Answers

What is CUSIP 829401108?
CUSIP 829401108 identifies SION - Sionna Therapeutics, Inc. - Common Stock SH in SEC institutional holdings data.

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Top shareholders of SION - Sionna Therapeutics, Inc. - Common Stock SH (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
RA CAPITAL MANAGEMENT, L.P.
13F
Company
23%
10,445,322
$181,226,337 30 Jun 2025
13F
TPG GP A, LLC
13F 13D/G
Company
15%
from 13D/G
6,744,962
$117,025,091 30 Jun 2025
ORBIMED ADVISORS LLC
13F
Company
8.3%
3,704,959
$64,281,039 30 Jun 2025
13F
Atlas Venture Life Science Advisors, LLC
13F
Company
8.2%
3,694,020
$64,091,247 30 Jun 2025
13F
JPMORGAN CHASE & CO
13D/G 13F
Company
4.4%
1,980,626
$58,251,993 -$7,075,145 30 Sep 2025
VIKING GLOBAL INVESTORS LP
13F 13D/G
Company
6.7%
from 13D/G
3,195,181
$55,436,390 30 Jun 2025
Enavate Sciences GP, LLC
13F 13D/G
Company
5.6%
from 13D/G
2,478,030
$42,993,821 30 Jun 2025
PERCEPTIVE ADVISORS LLC
13F
Company
2.7%
1,216,045
$21,098,381 30 Jun 2025
13F
BRAIDWELL LP
13F
Company
2.4%
1,081,855
$18,770,184 30 Jun 2025
13F
DEERFIELD MANAGEMENT COMPANY, L.P.
13F
Company
2.2%
970,590
$16,839,737 30 Jun 2025
13F
Aberdeen Group plc
13F
Company
2.1%
950,547
$16,491,990 30 Jun 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
1.9%
861,238
$14,943,000 30 Jun 2025
13F
JENNISON ASSOCIATES LLC
13F
Company
1.7%
752,800
$13,061,080 30 Jun 2025
13F
BlackRock, Inc.
13F
Company
1.4%
637,104
$11,053,754 30 Jun 2025
13F
VANGUARD GROUP INC
13F
Company
1.4%
630,351
$10,936,590 30 Jun 2025
13F
FRANKLIN RESOURCES INC
13F
Company
1.1%
500,023
$8,675,399 30 Jun 2025
13F
BAKER BROS. ADVISORS LP
13F
Company
0.89%
400,000
$6,940,000 30 Jun 2025
13F
Soleus Capital Management, L.P.
13F
Company
0.84%
376,000
$6,523,600 30 Jun 2025
13F
Siren, L.L.C.
13F
Individual
0.72%
325,000
$5,638,750 30 Jun 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
0.64%
289,275
$5,019,818 30 Jun 2025
13F
AMERIPRISE FINANCIAL INC
13F
Company
0.53%
236,813
$4,108,706 30 Jun 2025
13F
Alyeska Investment Group, L.P.
13F
Company
0.41%
186,222
$3,230,952 30 Jun 2025
13F
SILVERARC CAPITAL MANAGEMENT, LLC
13F
Company
0.41%
186,015
$3,227,360 30 Jun 2025
13F
PRUDENTIAL FINANCIAL INC
13F
Company
0.3%
135,185
$2,345,460 30 Jun 2025
13F
CITADEL ADVISORS LLC
13F
Company
0.29%
129,912
$2,253,973 30 Jun 2025
13F
STATE STREET CORP
13F
Company
0.28%
124,518
$2,160,387 30 Jun 2025
13F
Rock Springs Capital Management LP
13F
Company
0.22%
99,429
$1,725,093 30 Jun 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.21%
92,832
$1,610,635 30 Jun 2025
13F
NORTHERN TRUST CORP
13F
Company
0.2%
91,890
$1,594,291 30 Jun 2025
13F
DRIEHAUS CAPITAL MANAGEMENT LLC
13F
Company
0.19%
83,850
$1,454,798 30 Jun 2025
13F
Woodline Partners LP
13F
Company
0.18%
80,000
$1,388,000 30 Jun 2025
13F
UBS Group AG
13F
Company
0.11%
51,367
$891,217 30 Jun 2025
13F
Holocene Advisors, LP
13F
Company
0.11%
50,000
$867,500 30 Jun 2025
13F
TD ASSET MANAGEMENT INC
13F
Company
0.11%
49,966
$866,910 30 Jun 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
0.1%
46,048
$798,933 30 Jun 2025
13F
MORGAN STANLEY
13F
Company
0.1%
44,018
$763,712 30 Jun 2025
13F
MANUFACTURERS LIFE INSURANCE COMPANY, THE
13F
Company
0.08%
38,038
$659,959 30 Jun 2025
13F
RENAISSANCE TECHNOLOGIES LLC
13F
Company
0.06%
26,000
$451,100 30 Jun 2025
13F
Bank of New York Mellon Corp
13F
Company
0.05%
24,131
$418,673 30 Jun 2025
13F
BARCLAYS PLC
13F
Company
0.05%
23,022
$399,431 30 Jun 2025
13F
RHUMBLINE ADVISERS
13F
Company
0.04%
17,670
$306,568 30 Jun 2025
13F
BANTAMAC CAPITAL, LLC
13F
Company
0.04%
16,975
$294,516 30 Jun 2025
13F
POLEN CAPITAL MANAGEMENT LLC
13F
Company
0.04%
16,975
$294,516 30 Jun 2025
13F
Nuveen, LLC
13F
Company
0.04%
16,040
$278,294 30 Jun 2025
13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
0.03%
14,834
$257,370 30 Jun 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.03%
14,034
$243,490 30 Jun 2025
13F
COMMONWEALTH EQUITY SERVICES, LLC
13F
Company
0.03%
14,017
$243,000 30 Jun 2025
13F
DEUTSCHE BANK AG\
13F
Company
0.02%
9,596
$166,491 30 Jun 2025
13F
MetLife Investment Management, LLC
13F
Company
0.02%
8,033
$139,373 30 Jun 2025
13F
NEW YORK STATE COMMON RETIREMENT FUND
13F
Company
0.02%
6,800
$117,980 30 Jun 2025
13F

Institutional Holders of Sionna Therapeutics, Inc. - Common Stock SH (SION) as of Q3 2025

As of 30 Sep 2025, Sionna Therapeutics, Inc. - Common Stock SH (SION) was held by 78 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 42,840,564 shares. The largest 10 holders included RA CAPITAL MANAGEMENT, L.P., TPG GP A, LLC, ORBIMED ADVISORS LLC, Atlas Venture Life Science Advisors, LLC, VIKING GLOBAL INVESTORS LP, ENAVATE SCIENCES GP, LLC, JPMORGAN CHASE & CO, PERCEPTIVE ADVISORS LLC, VANGUARD GROUP INC, and JENNISON ASSOCIATES LLC. This page lists 78 institutional shareholders reporting positions in this security for the Q3 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q3 2025 vs Q2 2025 Across Filers

Q2 2025 holders
65
Q3 2025 holders
78
Holder diff
13
Investor Q2 2025 Shares Q3 2025 Shares Share Diff Share Chg % Q2 2025 Value $ Q3 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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