Protagonist Therapeutics, Inc - Common Stock (PTGX)
CUSIP: 74366E102
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / Common Stock
- Shares outstanding
- 62,457,444
- Total 13F shares
- 70,709,233
- Share change
- -562,363
- Total reported value
- $6,175,381,025
- Put/Call ratio
- 5.8%
- Price per share
- $87.34
- Number of holders
- 310
- Value change
- +$99,663,953
- Number of buys
- 160
- Number of sells
- 143
Quarterly Holders Quick Answers
What is CUSIP 74366E102?
CUSIP 74366E102 identifies PTGX - Protagonist Therapeutics, Inc - Common Stock in SEC institutional holdings data.
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Recent filing periods for CUSIP 74366E102:
Top shareholders of PTGX - Protagonist Therapeutics, Inc - Common Stock (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| BlackRock, Inc. |
13F
13D/G
|
Company |
14%
from 13D/G
|
9,404,232
|
$624,723,149 | — | 30 Sep 2025 | |
| Farallon Capital Partners, L.P. |
13D/G
|
Dapice Joshua J. |
10%
|
6,248,013
|
$545,701,455 | +$25,461,794 | 31 Dec 2025 | |
| FARALLON CAPITAL MANAGEMENT LLC |
13F
|
Company |
9.9%
|
6,196,006
|
$411,600,679 | — | 30 Sep 2025 | |
| RTW INVESTMENTS, LP |
13D/G
13F
|
Company |
8.1%
|
5,059,053
|
$405,989,003 | $0 | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
6.8%
|
4,257,229
|
$282,807,724 | — | 30 Sep 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
|
Company |
5.1%
|
3,171,423
|
$254,506,696 | $0 | 31 Dec 2025 | |
| STATE STREET CORP |
13F
13D/G
|
Company · STATE STREET CORPORATION |
5.2%
from 13D/G
|
3,165,795
|
$210,303,762 | — | 30 Sep 2025 | |
| BVF INC/IL |
13F
|
Company |
4.1%
|
2,560,916
|
$170,121,650 | — | 30 Sep 2025 | |
| BIOTECHNOLOGY VALUE FUND L P |
13D/G
|
BVF PARTNERS L P/IL |
4.1%
|
2,560,916
|
$170,121,650 | -$43,187,804 | 30 Sep 2025 | |
| JOHNSON & JOHNSON |
13F
|
Company |
3.9%
|
2,449,183
|
$162,699,227 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
3%
|
1,896,008
|
$125,951,812 | — | 30 Sep 2025 | |
| Deep Track Capital, LP |
13D/G
13F
|
Company |
2.8%
|
1,715,691
|
$113,973,353 | -$101,924,147 | 30 Sep 2025 | |
| Woodline Partners LP |
13F
|
Company |
2.3%
|
1,438,247
|
$95,542,748 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
2.3%
|
1,416,646
|
$94,122,036 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2%
|
1,220,436
|
$81,075,000 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
1.8%
|
1,139,854
|
$75,720,501 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
1.8%
|
1,100,821
|
$73,165,449 | — | 30 Sep 2025 | |
| MARSHALL WACE, LLP |
13F
|
Company |
1.7%
|
1,085,564
|
$72,114,017 | — | 30 Sep 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
1.6%
|
1,030,134
|
$68,431,802 | — | 30 Sep 2025 | |
| Commodore Capital LP |
13F
|
Company |
1.6%
|
1,025,000
|
$68,090,750 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
1.6%
|
1,003,706
|
$66,676,188 | — | 30 Sep 2025 | |
| ADAR1 Capital Management, LLC |
13F
|
Company |
1.6%
|
989,182
|
$65,711,360 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
1.3%
|
829,877
|
$55,128,729 | — | 30 Sep 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
1.3%
|
822,212
|
$54,619,543 | — | 30 Sep 2025 | |
| Jefferies Financial Group Inc. |
13F
|
Company |
1.3%
|
821,503
|
$54,572,444 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
1.3%
|
781,711
|
$51,929,062 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
1.2%
|
768,359
|
$51,042,146 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
1.1%
|
718,202
|
$47,710,159 | — | 30 Sep 2025 | |
| Lynx1 Capital Management LP |
13F
|
Company |
1.1%
|
700,014
|
$46,501,930 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.97%
|
603,222
|
$40,072,039 | — | 30 Sep 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.96%
|
600,047
|
$39,861,248 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.89%
|
552,877
|
$36,727,619 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
0.83%
|
520,664
|
$34,587,709 | — | 30 Sep 2025 | |
| MANGROVE PARTNERS IM, LLC |
13F
|
Company |
0.77%
|
478,413
|
$31,780,976 | — | 30 Sep 2025 | |
| BNP Paribas Asset Management Holding S.A. |
13F
|
Company |
0.72%
|
451,766
|
$30,011,000 | — | 30 Sep 2025 | |
| Focus Partners Wealth |
13F
|
Company |
0.72%
|
448,988
|
$29,826,273 | — | 30 Sep 2025 | |
| TORONTO DOMINION BANK |
13F
|
Company |
0.71%
|
445,440
|
$29,590,579 | — | 30 Sep 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.7%
|
438,515
|
$29,127,247 | — | 30 Sep 2025 | |
| 683 Capital Management, LLC |
13F
|
Company |
0.65%
|
407,500
|
$27,070,225 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.58%
|
363,261
|
$24,131,429 | — | 30 Sep 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
0.52%
|
326,088
|
$21,662,027 | — | 30 Sep 2025 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.49%
|
305,419
|
$20,288,984 | — | 30 Sep 2025 | |
| Logos Global Management LP |
13F
|
Company |
0.48%
|
300,000
|
$19,929,000 | — | 30 Sep 2025 | |
| RAYMOND JAMES FINANCIAL INC |
13F
|
Company |
0.47%
|
294,296
|
$19,550,084 | — | 30 Sep 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
0.42%
|
260,854
|
$17,328,531 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.4%
|
252,400
|
$16,766,932 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.38%
|
237,881
|
$15,802,435 | — | 30 Sep 2025 | |
| PUBLIC SECTOR PENSION INVESTMENT BOARD |
13F
|
Company |
0.37%
|
228,146
|
$15,155,739 | — | 30 Sep 2025 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.35%
|
220,600
|
$14,654,458 | — | 30 Sep 2025 | |
| KENNEDY CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.33%
|
208,437
|
$13,846,470 | — | 30 Sep 2025 |
Institutional Holders of Protagonist Therapeutics, Inc - Common Stock (PTGX) as of Q4 2025
As of 31 Dec 2025,
Protagonist Therapeutics, Inc - Common Stock (PTGX) was held by
310 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
70,709,233 shares.
The largest 10 holders included
BlackRock, Inc., FARALLON CAPITAL MANAGEMENT LLC, VANGUARD GROUP INC, RTW INVESTMENTS, LP, STATE STREET CORP, WELLINGTON MANAGEMENT GROUP LLP, UBS Group AG, JANUS HENDERSON GROUP PLC, JOHNSON & JOHNSON, and Invesco Ltd..
This page lists
310
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
274
Q4 2025 holders
310
Holder diff
36
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.