What does CUSIP 74366E102 represent in this 13F holders report?

CUSIP 74366E102 is the security identifier for PTGX - Protagonist Therapeutics, Inc - Common Stock used to aggregate holder disclosures.

How many institutions held PTGX - Protagonist Therapeutics, Inc - Common Stock in Q4 2021?

144 institutional investors reported PTGX - Protagonist Therapeutics, Inc - Common Stock for Q4 2021. Use the holders table for investor-level position and value details.

Protagonist Therapeutics, Inc - Common Stock (PTGX)

CUSIP: 74366E102

Q4 2021 13F Holders as of 31 Dec 2021

Type / Class: Equity / Common Stock
Shares outstanding: 63,850,747
Total 13F shares: 49,204,800
Share change: +2,357,782
Total reported value: $1,682,561,970
Put/Call ratio: 53%
Price per share: $34.20
Number of holders: 144
Value change: +$93,460,895
Number of buys: 84
Number of sells: 51

Quarterly Holders Quick Answers

What is CUSIP 74366E102?
CUSIP 74366E102 identifies PTGX - Protagonist Therapeutics, Inc - Common Stock in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2022
Previous quarter: Q3 2021

Recent filing periods for CUSIP 74366E102:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of PTGX - Protagonist Therapeutics, Inc - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	10%	6,492,638	$115,049,000	—	30 Sep 2021	13F
Point72 Asset Management, L.P.	13F	Company	6.9%	4,387,300	$77,743,000	—	30 Sep 2021	13F
BVF INC/IL	13F	Company	6.1%	3,901,759	$69,139,000	—	30 Sep 2021	13F
BlackRock Finance, Inc.	13F	Company	5%	3,199,496	$56,695,000	—	30 Sep 2021	13F
JOHNSON & JOHNSON	13F	Company	3.8%	2,449,183	$43,400,000	—	30 Sep 2021	13F
FARALLON CAPITAL MANAGEMENT LLC	13F	Company	3.7%	2,392,000	$42,386,000	—	30 Sep 2021	13F
VANGUARD GROUP INC	13F	Company	3.7%	2,353,786	$41,710,000	—	30 Sep 2021	13F
STATE STREET CORP	13F	Company	3.2%	2,013,979	$35,688,000	—	30 Sep 2021	13F
RTW INVESTMENTS, LP	13F	Company	2.7%	1,753,695	$31,075,000	—	30 Sep 2021	13F
Artal Group S.A.	13F	Company	2.3%	1,500,000	$26,580,000	—	30 Sep 2021	13F
EcoR1 Capital, LLC	13F	Company	2.3%	1,443,800	$25,584,000	—	30 Sep 2021	13F
DEERFIELD MANAGEMENT COMPANY, L.P.	13F	Company	2.2%	1,394,000	$24,702,000	—	30 Sep 2021	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	1.4%	875,732	$15,518,000	—	30 Sep 2021	13F
DEUTSCHE BANK AG\	13F	Company	1.3%	823,290	$14,588,000	—	30 Sep 2021	13F
Obermeyer Wealth Partners	13F	Company	1.2%	776,689	$13,763,000	—	30 Sep 2021	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	1.1%	728,930	$12,916,000	—	30 Sep 2021	13F
VOLORIDGE INVESTMENT MANAGEMENT, LLC	13F	Company	0.86%	550,083	$9,747,000	—	30 Sep 2021	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.82%	522,871	$9,265,000	—	30 Sep 2021	13F
Commodore Capital LP	13F	Company	0.78%	498,079	$8,826,000	—	30 Sep 2021	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	0.77%	491,641	$8,712,000	—	30 Sep 2021	13F
MORGAN STANLEY	13F	Company	0.74%	474,306	$8,405,000	—	30 Sep 2021	13F
NORTHERN TRUST CORP	13F	Company	0.72%	456,977	$8,098,000	—	30 Sep 2021	13F
JPMORGAN CHASE & CO	13F	Company	0.67%	428,695	$7,597,000	—	30 Sep 2021	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.66%	423,195	$7,499,000	—	30 Sep 2021	13F
Altium Capital Management LLC	13F	Company	0.54%	346,000	$6,131,000	—	30 Sep 2021	13F
Opaleye Management Inc.	13F	Company	0.52%	330,222	$5,852,000	—	30 Sep 2021	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.49%	309,832	$5,491,000	—	30 Sep 2021	13F
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F	Company	0.47%	300,045	$5,317,000	—	30 Sep 2021	13F
Sofinnova Investments, Inc.	13F	Company	0.47%	297,709	$5,275,000	—	30 Sep 2021	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.42%	267,383	$4,738,000	—	30 Sep 2021	13F
SPHERA FUNDS MANAGEMENT LTD.	13F	Company	0.41%	260,379	$4,614,000	—	30 Sep 2021	13F
Polar Capital Holdings Plc	13F	Company	0.34%	218,936	$3,880,000	—	30 Sep 2021	13F
ROTHSCHILD & CO ASSET MANAGEMENT US INC.	13F	Company	0.34%	217,483	$3,854,000	—	30 Sep 2021	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.23%	145,300	$2,575,000	—	30 Sep 2021	13F
Twin Lakes Capital Management, LLC	13F	Company	0.22%	139,287	$2,468,000	—	30 Sep 2021	13F
FEDERATED HERMES, INC.	13F	Company	0.21%	131,282	$2,326,000	—	30 Sep 2021	13F
Bank of New York Mellon Corp	13F	Company	0.21%	131,133	$2,324,000	—	30 Sep 2021	13F
CITADEL ADVISORS LLC	13F	Company	0.19%	118,704	$2,104,000	—	30 Sep 2021	13F
D. E. Shaw & Co., Inc.	13F	Company	0.18%	115,913	$2,054,000	—	30 Sep 2021	13F
KENNEDY CAPITAL MANAGEMENT LLC	13F	Company	0.18%	112,265	$1,989,000	—	30 Sep 2021	13F
Caption Management, LLC	13F	Company	0.17%	110,000	$1,949,000	—	30 Sep 2021	13F
JABODON PT CO	13F	Company	0.14%	90,656	$1,606,000	—	30 Sep 2021	13F
Sio Capital Management, LLC	13F	Company	0.14%	90,000	$1,595,000	—	30 Sep 2021	13F
Swiss National Bank	13F	Company	0.14%	87,400	$1,549,000	—	30 Sep 2021	13F
Tekla Capital Management LLC	13F	Company	0.14%	86,237	$1,528,000	—	30 Sep 2021	13F
S.c.a. Candriam	13F	Individual	0.13%	83,646	$1,482,000	—	30 Sep 2021	13F
Russell Investments Group, Ltd.	13F	Company	0.12%	77,002	$1,363,000	—	30 Sep 2021	13F
SILVERCREST ASSET MANAGEMENT GROUP LLC	13F	Company	0.11%	71,343	$1,264,000	—	30 Sep 2021	13F
STATE OF WISCONSIN INVESTMENT BOARD	13F	Company	0.11%	71,200	$1,262,000	—	30 Sep 2021	13F
Nuveen Asset Management, LLC	13F	Company	0.26%	163,086	$1,261,000	—	30 Sep 2021	13F

Institutional Holders of Protagonist Therapeutics, Inc - Common Stock (PTGX) as of Q4 2021

As of 31 Dec 2021, Protagonist Therapeutics, Inc - Common Stock (PTGX) was held by 144 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 49,204,800 shares. The largest 10 holders included FMR LLC, BVF INC/IL, BlackRock Inc., EcoR1 Capital, LLC, RTW INVESTMENTS, LP, STATE STREET CORP, JOHNSON & JOHNSON, Point72 Asset Management, L.P., VANGUARD GROUP INC, and FARALLON CAPITAL MANAGEMENT LLC. This page lists 145 institutional shareholders reporting positions in this security for the Q4 2021 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2021 vs Q3 2021 Across Filers

Q3 2021 holders

126

Q4 2021 holders

144

Holder diff

Investor	Q3 2021 Shares	Q4 2021 Shares	Share Diff	Share Chg %	Q3 2021 Value $	Q4 2021 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.