Oruka Therapeutics, Inc. - Common Stock, $0.001 par value per share (ORKA)

CUSIP: 687604108

Q4 2025 13F Holders as of 31 Dec 2025

Holder snapshot 7 signals
Share change
+5,589,327
Put/Call ratio
85%
SEC-reported price per share
$30.31
Number of holders
144
Value change
+$170,793,609
Number of buys
93
Open additional details 1 more signal available
Number of sells
24
Security identity Names, identifiers, and filing context for this profile. 1 source field
Shares outstanding
74,732,908

Security key

687604108

Report period

Q4 2025

Institutions

144

Top holders

10

Ownership snapshot

Top reported holders of ORKA - Oruka Therapeutics, Inc. - Common Stock, $0.001 par value per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Venrock Healthcare Capita...
Disclosed value leader
FMR LLC
Comparable rows
15/15
Latest evidence
31 Dec 2025
13D/G 3/4/5 13F Lead comparable stake: 9.9% 13D/G row: Venrock Healthcare Capital Partners III, L.P. Showing 1-6 of 15 holder rows.

Quick read

Venrock Healthcare Capital Partners III, L.P. leads the comparable SEC ownership view at 9.9%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Venrock Healthcare Capital Partners III, L.P.'s linked filing trail.
Comparable ownership Top 5
Venrock Healthcare Capital Partne... 9.9%
BlackRock, Inc. 6.6%
Deep Track Capital, LP 4.5%
RTW INVESTMENTS, LP 4.3%
FMR LLC 9.7%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Venrock Healthcare Capital Partners III, L.P.
13D/G 3/4/5
10%+ Owner
9.9%
$94,411,973
4,909,619 shares
+$14,637,703 30 Sep 2025
BlackRock, Inc.
13D/G 13F
Company
6.6%
$96,248,890
3,175,483 shares
+$29,642,149 31 Dec 2025
Deep Track Capital, LP
13D/G 13F
Company
4.5%
$65,515,368
2,161,510 shares
+$8,023,966 31 Dec 2025
RTW INVESTMENTS, LP
13D/G 13F
Company
4.3%
$62,382,466
2,058,148 shares
+$3,409,845 31 Dec 2025
FMR LLC
13F
Company
13F
9.7%
$139,564,052
7,257,621 shares
30 Sep 2025
Venrock Adviser, LLC
13F
Company
13F
5.6%
$79,774,270
4,148,428 shares
30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions
144
Shares
52,853,967
Rows available
144
Investor Option Weight % Change % SEC-reported value * Price Shares Share Change Activity Report Period

* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders
104
Q4 2025 holders
144
Holder diff
40
Investor Q3 2025 Shares Q4 2025 Shares Share Diff Share Chg % Q3 2025 value Q4 2025 value Value change Value Chg %
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