Security key
68375N103
OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)
CUSIP: 68375N103
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / Common Stock, par value $0.01 per share
- Shares outstanding
- 770,989,043
- Total 13F shares
- 199,275,448
- Share change
- +3,394,084
- Total reported value
- $251,138,539
- Put/Call ratio
- 13%
- Price per share
- $1.26
- Number of holders
- 217
- Value change
- +$3,655,748
- Number of buys
- 67
- Number of sells
- 109
Report period
Q4 2025
Institutions
217
Top holders
10
OPK full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
OPKO HEALTH, INC. SEC filings
OPKO HEALTH, INC. company facts
OPKO HEALTH, INC. 13D/G history
Broader feeds
Reporting periods
Holder history for CUSIP 68375N103
Recent filing periods:
Top shareholders of OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| Et al Phillip Frost MD |
13D/G
3/4/5
|
FROST PHILLIP MD ET AL · CEO & Chairman, Director, 10%+ Owner |
33%
|
252,884,406
|
$351,509,324 | +$674,150 | 30 Sep 2025 | |
| Rubric Capital Management LP |
13F
13D/G
|
Company |
6%
from 13D/G
|
47,791,243
|
$74,076,427 | — | 30 Sep 2025 | |
| Jane Ph D. Hsiao |
13D/G
3/4/5
|
HSIAO JANE PH D · Vice Chairman & CTO, Director |
4.5%
|
35,677,284
|
$50,304,970 | $0 | 02 Apr 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
4.9%
|
37,535,897
|
$58,180,641 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13F
|
Company |
4.3%
|
33,172,384
|
$51,417,196 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.4%
|
10,993,345
|
$17,043,109 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.2%
|
8,997,940
|
$13,946,807 | — | 30 Sep 2025 | |
| Whitefort Capital Management, LP |
13F
|
Company |
0.64%
|
4,900,000
|
$7,595,000 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.62%
|
4,775,536
|
$7,402,080 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.49%
|
3,768,934
|
$5,841,848 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.47%
|
3,657,846
|
$5,669,661 | — | 30 Sep 2025 | |
| AQR CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.37%
|
2,873,416
|
$4,453,795 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.31%
|
2,386,535
|
$3,699,129 | — | 30 Sep 2025 | |
| AWM Investment Company, Inc. |
13F
|
Company |
0.29%
|
2,200,000
|
$3,410,000 | — | 30 Sep 2025 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.22%
|
1,667,368
|
$2,582,192 | — | 30 Sep 2025 | |
| Y.D. More Investments Ltd |
13F
|
Company |
0.19%
|
1,499,118
|
$2,235,527 | — | 30 Sep 2025 | |
| WASHINGTON GROWTH STRATEGIES LLC |
13F
|
Company |
0.18%
|
1,356,124
|
$2,101,993 | — | 30 Sep 2025 | |
| PFG Investments, LLC |
13F
|
Company |
0.17%
|
1,337,375
|
$2,072,931 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.17%
|
1,313,882
|
$2,036,518 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.17%
|
1,276,868
|
$1,979,146 | — | 30 Sep 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.16%
|
1,255,647
|
$1,946,253 | — | 30 Sep 2025 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.16%
|
1,218,002
|
$1,887,903 | — | 30 Sep 2025 | |
| Weiss Asset Management LP |
13F
|
Company |
0.15%
|
1,130,771
|
$1,752,695 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.13%
|
1,017,561
|
$1,577,220 | — | 30 Sep 2025 | |
| Tejara Capital Ltd |
13F
|
Company |
0.11%
|
877,941
|
$1,360,809 | — | 30 Sep 2025 | |
| Swiss National Bank |
13F
|
Company |
0.11%
|
845,755
|
$1,310,920 | — | 30 Sep 2025 | |
| Nuveen, LLC |
13F
|
Company |
0.11%
|
841,836
|
$1,304,846 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.11%
|
837,601
|
$1,298,282 | — | 30 Sep 2025 | |
| Assenagon Asset Management S.A. |
13F
|
Company |
0.09%
|
690,200
|
$1,030,015 | — | 30 Sep 2025 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.09%
|
673,565
|
$1,044,026 | — | 30 Sep 2025 | |
| COMMONWEALTH EQUITY SERVICES, LLC |
13F
|
Company |
0.08%
|
592,330
|
$918,000 | — | 30 Sep 2025 | |
| BARCLAYS PLC |
13F
|
Company |
0.08%
|
587,753
|
$911,017 | — | 30 Sep 2025 | |
| RHUMBLINE ADVISERS |
13F
|
Company |
0.07%
|
555,382
|
$860,833 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
0.07%
|
527,411
|
$817,487 | — | 30 Sep 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
0.06%
|
475,190
|
$736,545 | — | 30 Sep 2025 | |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
13F
|
Company |
0.05%
|
415,386
|
$643,848 | — | 30 Sep 2025 | |
| Connor, Clark & Lunn Investment Management Ltd. |
13F
|
Company |
0.05%
|
392,761
|
$608,780 | — | 30 Sep 2025 | |
| Legal & General Group Plc |
13F
|
Company |
0.05%
|
386,837
|
$598,213 | — | 30 Sep 2025 | |
| CAPITAL ADVISORS INC/OK |
13F
|
Company |
0.05%
|
370,000
|
$36,640 | — | 30 Sep 2025 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
0.04%
|
344,097
|
$533,350 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.04%
|
343,286
|
$533,000 | — | 30 Sep 2025 | |
| WELLS FARGO & COMPANY/MN |
13F
|
Company |
0.04%
|
342,486
|
$530,854 | — | 30 Sep 2025 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
13F
|
Company |
0.04%
|
297,835
|
$461,644 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.04%
|
279,875
|
$433,806 | — | 30 Sep 2025 | |
| IEQ CAPITAL, LLC |
13F
|
Company |
0.04%
|
277,594
|
$430,271 | — | 30 Sep 2025 | |
| DEUTSCHE BANK AG\ |
13F
|
Company |
0.04%
|
275,188
|
$426,541 | — | 30 Sep 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.04%
|
272,866
|
$423,000 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.03%
|
262,838
|
$407,399 | — | 30 Sep 2025 | |
| TUDOR INVESTMENT CORP ET AL |
13F
|
Company |
0.03%
|
244,821
|
$379,473 | — | 30 Sep 2025 | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
13F
|
Company |
0.03%
|
236,722
|
$366,919 | — | 30 Sep 2025 |
Institutional Holders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) as of Q4 2025
As of 31 Dec 2025,
OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) was held by
217 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
199,275,448 shares.
The largest 10 holders included
Rubric Capital Management LP, BlackRock, Inc., VANGUARD GROUP INC, GEODE CAPITAL MANAGEMENT, LLC, STATE STREET CORP, GOLDMAN SACHS GROUP INC, UBS Group AG, Whitefort Capital Management, LP, CHARLES SCHWAB INVESTMENT MANAGEMENT INC, and NORTHERN TRUST CORP.
This page lists
217
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
229
Q4 2025 holders
217
Holder diff
-12
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.