OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

Historical Holders from Q1 2014 to Q4 2025

Type / Class
Equity / Common Stock, par value $0.01 per share
Symbol
OPK on Nasdaq
Shares outstanding
770,989,043
Price per share
$1.26
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares as of 30 Sep 2025
195,969,728
Total reported value
$303,592,132
% of total 13F portfolios
0%
Share change
-8,391,178
Value change
-$11,769,777
Avg buy value change
+0%
Avg sell value change
-0%
Number of holders
229
Price from insider filings
$1.34
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FROST PHILLIP MD ET AL 33% +3.4% $351,509,324 +$674,150 252,884,406 +0.19% FROST PHILLIP MD ET AL 30 Sep 2025
Rubric Capital Management LP 6% $63,137,011 47,791,243 Rubric Capital Management LP 30 Jun 2025
HSIAO JANE PH D 4.5% $50,304,970 35,677,284 HSIAO JANE PH D 02 Apr 2025
As of 30 Sep 2025, OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) has 229 institutional shareholders filing 13F forms. They hold 195,969,728 shares. of 770,989,043 outstanding shares (25%) .

Top 25 institutional shareholders own 23% of the company.

Filer Ownership Nb Shares Share Change % Portfolio % Holdings Value
Rubric Capital Management LP 6.2% 47,791,243 0% 0.99% $74,076,427
VANGUARD GROUP INC 4.9% 37,535,897 -1.8% 0% $58,180,641
BlackRock, Inc. 4.3% 33,172,384 +5.5% 0% $51,417,196
GEODE CAPITAL MANAGEMENT, LLC 1.4% 10,993,345 +5.5% 0% $17,043,109
STATE STREET CORP 1.2% 8,997,940 +4.8% 0% $13,946,807
Whitefort Capital Management, LP 0.64% 4,900,000 +176% 2.5% $7,595,000
UBS Group AG 0.62% 4,775,536 -17% 0% $7,402,080
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.49% 3,768,934 +12% 0% $5,841,848
NORTHERN TRUST CORP 0.47% 3,657,846 +5% 0% $5,669,661
AQR CAPITAL MANAGEMENT LLC 0.37% 2,873,416 +207% 0% $4,453,795
GOLDMAN SACHS GROUP INC 0.31% 2,386,535 -15% 0% $3,699,129
AWM Investment Company, Inc. 0.29% 2,200,000 +10% 0.32% $3,410,000
DIMENSIONAL FUND ADVISORS LP 0.22% 1,667,368 -14% 0% $2,582,192
Y.D. More Investments Ltd 0.19% 1,499,118 -1.9% 0.13% $2,235,527
WASHINGTON GROWTH STRATEGIES LLC 0.18% 1,356,124 0% 1.5% $2,101,993
PFG Investments, LLC 0.17% 1,337,375 +5.7% 0.11% $2,072,931
BANK OF AMERICA CORP /DE/ 0.17% 1,313,882 -31% 0% $2,036,518
Bank of New York Mellon Corp 0.17% 1,276,868 +11% 0% $1,979,146
TWO SIGMA INVESTMENTS, LP 0.16% 1,255,647 -32% 0% $1,946,253
Voya Investment Management LLC 0.16% 1,218,002 -7.7% 0% $1,887,903
Weiss Asset Management LP 0.15% 1,130,771 -76% 0.03% $1,752,695
Invesco Ltd. 0.13% 1,017,561 -26% 0% $1,577,220
Tejara Capital Ltd 0.11% 877,941 -7.2% 0.75% $1,360,809
Swiss National Bank 0.11% 845,755 +46% 0% $1,310,920
Nuveen, LLC 0.11% 841,836 -25% 0% $1,304,846

Institutional Holders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (% of par) Investors
2025 Q4 840,228 $1,075,204 -$164,717 126% 9
2025 Q3 195,969,728 $303,592,132 -$11,769,777 155% 229
2025 Q2 205,024,725 $270,648,264 -$60,618,128 132% 215
2025 Q1 241,258,198 $400,533,423 +$72,053,389 166% 247
2024 Q4 197,412,433 $290,239,287 +$15,903,156 147% 230
2024 Q3 186,501,814 $277,905,256 +$7,881,691 149% 227
2024 Q2 182,107,019 $227,651,201 +$32,281,850 125% 227
2024 Q1 158,173,650 $189,816,225 -$15,412,795 120% 218
2023 Q4 169,846,994 $256,508,174 +$2,949,820 151% 211
2023 Q3 167,041,124 $267,211,525 -$11,685,601 160% 219
2023 Q2 173,057,185 $374,930,496 -$7,391,066 217% 224
2023 Q1 177,714,344 $259,294,407 -$3,078,751 146% 218
2022 Q4 181,496,897 $226,809,289 -$10,191,947 125% 214
2022 Q3 186,517,226 $352,478,417 -$8,899,720 189% 200
2022 Q2 189,691,960 $479,863,957 -$13,941,817 253% 210
2022 Q1 194,629,054 $670,129,008 +$10,945,254 344% 215
2021 Q4 190,116,095 $914,661,536 +$32,672,752 480.99% 222
2021 Q3 183,228,658 $668,852,368 -$29,244,813 365% 196
2021 Q2 190,948,492 $773,257,740 +$54,948 405% 224
2021 Q1 190,493,255 $817,110,481 +$5,248,916 429% 230
2020 Q4 187,898,643 $742,332,468 -$29,923,745 395% 229
2020 Q3 195,530,381 $721,219,726 -$13,315,180 369% 207
2020 Q2 199,256,349 $679,095,576 +$131,091,146 340.99% 198
2020 Q1 161,765,902 $216,744,574 -$19,687,519 134% 167
2019 Q4 176,275,051 $259,136,088 +$41,988,405 147% 185
2019 Q3 147,149,372 $307,565,950 -$17,098,653 209% 173
2019 Q2 154,503,483 $376,518,250 -$4,451,090 243.99% 185
2019 Q1 159,227,289 $414,802,691 +$39,359,438 261% 185
2018 Q4 142,093,268 $427,280,395 -$32,150,016 301% 187
2018 Q3 152,164,350 $526,449,630 +$32,002,562 345.98% 197
2018 Q2 140,990,937 $662,674,682 +$30,418,093 470% 202
2018 Q1 134,703,173 $426,973,988 +$21,808,219 316.99% 210
2017 Q4 130,845,894 $641,134,531 -$11,914,079 490% 217
2017 Q3 131,515,339 $902,006,062 +$9,805,717 686% 228
2017 Q2 127,413,444 $838,468,204 -$14,499,676 658% 221
2017 Q1 131,302,704 $1,050,471,050 +$158,998,246 800% 232
2016 Q4 132,543,971 $1,235,029,545 +$47,421,334 930% 241
2016 Q3 127,239,733 $1,345,914,777 +$129,356,378 1,059% 260
2016 Q2 115,306,017 $1,077,026,990 +$41,618,153 934% 234
2016 Q1 109,453,682 $1,136,781,775 -$48,177,301 1,039% 248
2015 Q4 115,548,837 $1,161,220,963 -$134,688,417 1,005% 266
2015 Q3 123,052,830 $1,034,135,480 +$270,131,808 840.97% 256
2015 Q2 85,374,333 $1,372,644,135 +$79,586,364 1,607.96% 215
2015 Q1 80,721,201 $1,142,242,411 +$43,779,625 1,416.97% 189
2014 Q4 78,028,785 $779,583,900 +$30,051,903 999.01% 175
2014 Q3 74,739,528 $635,901,500 -$64,365,946 850.99% 180
2014 Q2 81,806,864 $723,162,643 +$87,038,633 884% 171
2014 Q1 72,774,020 $678,260,259 +$9,369,927 931.97% 165