OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

Historical Holders from Q1 2014 to Q3 2025

Symbol: OPK on Nasdaq
Type / Class: Equity / Common Stock, par value $0.01 per share
Shares outstanding: 770,989,043
All holders as of 30 Sep 2025: Q3 2025
Total 13F shares, excl. options: 195,947,137
Holdings value: $303,555,555
% of all portfolios: 0.001%
Number of holders: 227
Number of buys: 102
Number of sells: -66
Average buys %: +0%
Average sells %: -0%

Reported Shares, Excluding Options vs Price

Reported Value, Excluding Options

Total Investors

Significant Owners of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

Filer	Ownership	Change %	Holdings Value	Net Change	Nb Shares	Change %	Reporting Name	Report Period
FROST PHILLIP MD ET AL	32.8%	+3.4%	$351,509,324	+$674,150	252,884,406	+0.19%	FROST PHILLIP MD ET AL	30 Sep 2025
Rubric Capital Management LP	6.03%		$63,137,011		47,791,243		Rubric Capital Management LP	30 Jun 2025
HSIAO JANE PH D	4.5%		$50,304,970		35,677,284		HSIAO JANE PH D	02 Apr 2025

Institutional Holders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

Period	Reported Shares, Excl. Options	Value, Excl. Options	Change	Puts Notional Value	Calls Notional Value	Price	Investors
2025 Q3	195,947,137	$303,555,555	-$11,770,028	$195,610	$2,584,197	$1.55	227
2025 Q2	205,024,725	$270,648,264	-$60,618,128	$438,768	$1,968,780	$1.32	215
2025 Q1	241,258,198	$400,533,423	+$72,053,389	$669,478	$2,582,130	$1.66	247
2024 Q4	197,412,433	$290,239,287	+$15,903,156	$13,490,484	$5,255,838	$1.47	230
2024 Q3	186,501,814	$277,905,256	+$7,881,691	$15,031,504	$8,983,960	$1.49	227
2024 Q2	182,107,019	$227,651,201	+$32,281,850	$11,033,500	$5,290,375	$1.25	227
2024 Q1	158,173,650	$189,816,225	-$15,412,795	$377,520	$3,621,840	$1.2	218
2023 Q4	169,846,994	$256,508,174	+$2,949,820	$344,582	$3,844,762	$1.51	211
2023 Q3	167,041,124	$267,211,525	-$11,685,601	$1,799,360	$1,692,000	$1.6	219
2023 Q2	173,057,185	$374,930,496	-$7,391,066	$2,407,615	$1,243,712	$2.17	224
2023 Q1	177,714,344	$259,294,407	-$3,078,751	$1,628,630	$548,884	$1.46	218
2022 Q4	181,496,897	$226,809,289	-$10,191,947	$1,792,375	$1,040,000	$1.25	214
2022 Q3	186,517,226	$352,478,417	-$8,899,720	$5,387,000	$2,280,000	$1.89	200
2022 Q2	189,691,960	$479,863,957	-$13,941,817	$6,802,000	$3,653,000	$2.53	210
2022 Q1	194,629,054	$670,129,008	+$10,945,254	$11,609,000	$8,248,000	$3.44	215
2021 Q4	190,116,095	$914,661,536	+$32,672,752	$24,706,000	$29,663,000	$4.81	222
2021 Q3	183,228,658	$668,852,368	-$29,244,813	$11,427,000	$17,861,000	$3.65	196
2021 Q2	190,948,492	$773,257,740	+$54,948	$9,179,000	$20,617,000	$4.05	224
2021 Q1	190,493,255	$817,110,481	+$5,248,916	$9,097,000	$14,604,000	$4.29	230
2020 Q4	187,898,643	$742,332,468	-$29,923,745	$13,169,000	$23,043,000	$3.95	229
2020 Q3	195,530,381	$721,219,726	-$13,315,180	$10,633,000	$17,512,000	$3.69	207
2020 Q2	199,256,349	$679,095,576	+$131,091,146	$7,632,000	$9,892,000	$3.41	198
2020 Q1	161,765,902	$216,744,574	-$19,687,519	$2,672,000	$1,651,000	$1.34	167
2019 Q4	176,275,051	$259,136,088	+$41,988,405	$4,270,000	$2,166,000	$1.47	185
2019 Q3	147,149,372	$307,565,950	-$17,098,653	$5,472,000	$3,276,000	$2.09	173
2019 Q2	154,503,483	$376,518,250	-$4,451,090	$8,614,000	$3,496,000	$2.44	185
2019 Q1	159,227,289	$414,802,691	+$39,359,438	$10,875,000	$829,000	$2.61	185
2018 Q4	142,093,268	$427,280,395	-$32,150,016	$16,801,000	$6,741,000	$3.01	187
2018 Q3	152,164,350	$526,449,630	+$32,002,562	$16,019,000	$12,535,000	$3.46	197
2018 Q2	140,990,937	$662,674,682	+$30,418,093	$11,867,000	$14,815,000	$4.7	202
2018 Q1	134,703,173	$426,973,988	+$21,808,219	$5,158,000	$2,570,000	$3.17	210
2017 Q4	130,845,894	$641,134,531	-$11,914,079	$25,525,000	$13,359,000	$4.9	217
2017 Q3	131,515,339	$902,006,062	+$9,805,717	$41,043,000	$17,739,000	$6.86	228
2017 Q2	127,413,444	$838,468,204	-$14,499,676	$29,929,000	$6,232,000	$6.58	221
2017 Q1	131,302,704	$1,050,471,050	+$158,998,246	$56,679,000	$19,486,000	$8	232
2016 Q4	132,543,971	$1,235,029,545	+$47,421,334	$73,085,000	$62,407,000	$9.3	241
2016 Q3	127,239,733	$1,345,914,777	+$129,356,378	$74,540,000	$50,961,000	$10.59	260
2016 Q2	115,306,017	$1,077,026,990	+$41,618,153	$53,331,000	$27,775,000	$9.34	234
2016 Q1	109,453,682	$1,136,781,775	-$48,177,301	$69,336,000	$46,344,000	$10.39	248
2015 Q4	115,548,837	$1,161,220,963	-$134,688,417	$115,935,000	$86,108,000	$10.05	266
2015 Q3	123,052,830	$1,034,135,480	+$270,131,808	$108,106,000	$71,477,000	$8.41	256
2015 Q2	85,374,333	$1,372,644,135	+$79,586,364	$262,927,000	$117,608,000	$16.08	215
2015 Q1	80,721,201	$1,142,242,411	+$43,779,625	$124,125,000	$72,339,000	$14.17	189
2014 Q4	78,028,785	$779,583,900	+$30,051,903	$69,195,000	$71,288,000	$9.99	175
2014 Q3	74,739,528	$635,901,500	-$64,365,946	$60,858,000	$35,026,000	$8.51	180
2014 Q2	81,806,864	$723,162,643	+$87,038,633	$82,916,000	$48,518,000	$8.84	171
2014 Q1	72,774,020	$678,260,259	+$9,369,927	$65,176,000	$45,788,000	$9.32	165