Security Snapshot

OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) Institutional Ownership

CUSIP: 68375N103

13F Institutional Holders and Ownership History from Q1 2014 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

220

Shares (Excl. Options)

201,448,644

Price

$1.50

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+956,353
Value change
+$2,689,353
Number of holders
220
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
749,059,842
SEC-reported price per share
$1.34
Insider filing price
$1.34
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share is tracked under CUSIP 68375N103.
  • 220 institutions reported positions in Q2 2026.
  • 3 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 233 to 220 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $229,240,941 to $301,970,912.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 220 institutions filings for Q2 2026.

Open SEC evidence

Security key

68375N103

Latest holder period

Q2 2026

13F holders

220

13D/G owners

3

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
3
Security
OPK
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FROST PHILLIP MD ET AL 34% +3.9% $370,372,639 +$3,690,250 255,429,406 +1% FROST PHILLIP MD ET AL 29 Jun 2026
Rubric Capital Management LP 6% $63,137,011 47,791,243 Rubric Capital Management LP 30 Jun 2025
HSIAO JANE PH D 4.5% $50,304,970 35,677,284 HSIAO JANE PH D 02 Apr 2025

As of 30 Jun 2026, 220 institutional investors reported holding 201,448,644 shares of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK). This represents 27% of the company’s total 749,059,842 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
24%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Rubric Capital Management LP 6.4% 47,791,243 0% 0.66% $71,686,865
BlackRock, Inc. 4.9% 36,978,893 +2.1% 0% $55,468,342
VANGUARD CAPITAL MANAGEMENT LLC 2% 14,968,930 +3.2% 0% $22,453,395
VANGUARD PORTFOLIO MANAGEMENT LLC 2% 14,934,924 +1.1% 0% $22,402,386
GEODE CAPITAL MANAGEMENT, LLC 1.5% 11,581,027 +2.5% 0% $17,375,151
STATE STREET CORP 1.4% 10,309,070 +8.5% 0% $15,463,605
GOLDMAN SACHS GROUP INC 0.94% 7,035,492 -8.3% 0% $10,553,239
UBS Group AG 0.67% 5,006,284 -18% 0% $7,509,427
Whitefort Capital Management, LP 0.6% 4,511,412 +6.1% 1.7% $6,767,118
NORTHERN TRUST CORP 0.5% 3,756,163 +3.8% 0% $5,634,246
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.48% 3,596,980 +0.64% 0% $5,395,470
HIGHBRIDGE CAPITAL MANAGEMENT LLC 0.48% 3,593,925 0.19% $5,426,827
VANGUARD FIDUCIARY TRUST CO 0.36% 2,706,235 -1.3% 0% $4,059,353
AWM Investment Company, Inc. 0.28% 2,110,000 +0.48% 0.27% $3,165,000
MORGAN STANLEY 0.26% 1,975,027 +65% 0% $2,962,542
CITADEL ADVISORS LLC 0.19% 1,420,922 -32% 0% $2,131,383
WASHINGTON GROWTH STRATEGIES LLC 0.18% 1,356,124 0% 1.1% $2,034,186
Bank of New York Mellon Corp 0.18% 1,329,974 +3.9% 0% $1,994,961
DIMENSIONAL FUND ADVISORS LP 0.17% 1,267,741 -19% 0% $1,902,026
Y.D. More Investments Ltd 0.17% 1,257,568 -3.2% 0.06% $1,876,217
AQR CAPITAL MANAGEMENT LLC 0.17% 1,239,399 +62% 0% $1,859,101
OP Asset Management Ltd 0.15% 1,159,647 +5.2% 0.02% $1,739,471
VOYA INVESTMENT MANAGEMENT LLC 0.15% 1,094,111 -5.8% 0% $1,641,167
Clearstead Advisors, LLC 0.12% 883,288 -0.09% 0.01% $1,324,932
Nuveen, LLC 0.12% 863,035 +1.9% 0% $1,294,553

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
50
Latest
Q2 2026
Rows shown
1-25 of 50
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 201,448,644 $301,970,912 +$2,689,353 $1.50 220
2026 Q1 201,063,854 $229,240,941 +$1,886,217 $1.14 233
2025 Q4 199,275,448 $251,138,539 +$3,655,748 $1.26 217
2025 Q3 195,949,910 $303,559,853 -$11,801,008 $1.55 229
2025 Q2 205,024,725 $270,648,264 -$60,618,128 $1.32 215
2025 Q1 241,258,198 $400,533,423 +$72,053,389 $1.66 247
2024 Q4 197,412,433 $290,239,287 +$15,903,156 $1.47 230
2024 Q3 186,501,814 $277,905,256 +$7,881,691 $1.49 227
2024 Q2 182,107,019 $227,651,201 +$32,281,850 $1.25 227
2024 Q1 158,173,650 $189,816,225 -$15,412,795 $1.20 218
2023 Q4 169,846,994 $256,508,174 +$2,949,820 $1.51 211
2023 Q3 167,041,124 $267,211,525 -$11,685,601 $1.60 219
2023 Q2 173,057,185 $374,930,496 -$7,391,066 $2.17 224
2023 Q1 177,714,344 $259,294,407 -$3,078,751 $1.46 218
2022 Q4 181,496,897 $226,809,289 -$10,191,947 $1.25 214
2022 Q3 186,517,226 $352,478,417 -$8,899,720 $1.89 200
2022 Q2 189,691,960 $479,863,957 -$13,941,817 $2.53 210
2022 Q1 194,629,054 $670,129,008 +$10,945,254 $3.44 215
2021 Q4 190,116,095 $914,661,536 +$32,672,752 $4.81 222
2021 Q3 183,228,658 $668,852,368 -$29,244,813 $3.65 196
2021 Q2 190,948,492 $773,257,740 +$54,948 $4.05 224
2021 Q1 190,493,255 $817,110,481 +$5,248,916 $4.29 230
2020 Q4 187,898,643 $742,332,468 -$29,923,745 $3.95 229
2020 Q3 195,530,381 $721,219,726 -$13,315,180 $3.69 207
2020 Q2 199,256,349 $679,095,576 +$131,091,146 $3.41 198
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