Latest Period
Q1 2026
Security Snapshot
OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) Institutional Ownership
CUSIP: 68375N103
13F Institutional Holders and Ownership History from Q1 2014 to Q1 2026
Institutions Reporting
229
Shares (Excl. Options)
200,712,854
Price
$1.14
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- Type / Class
- Equity / Common Stock, par value $0.01 per share
- Symbol
- OPK on Nasdaq
- Shares outstanding
- 770,989,043
- Price per share
- $1.24
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 200,712,854
- Total reported value
- $228,840,801
- % of total 13F portfolios
- 0%
- Share change
- +1,780,115
- Value change
- +$1,843,790
- Number of holders
- 229
- Price from insider filings
- $1.24
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Key facts
- OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share is tracked under CUSIP 68375N103.
- 229 institutions reported positions in Q1 2026.
- 3 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 217 to 229 between Q4 2025 and Q1 2026.
- Reported value moved from $251,138,539 to $228,840,801.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 229 institutions filings for Q1 2026.
Security key
68375N103
Latest holder period
Q1 2026
13F holders
229
13D/G owners
3
CIK / CUSIP context first
Open Q1 2026 holders
OPK full holder history
OPKO HEALTH, INC. SEC filings
OPKO HEALTH, INC. company facts
OPKO HEALTH, INC. insider transactions
OPKO HEALTH, INC. 13D/G history
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 68375N103:
Significant Owners of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FROST PHILLIP MD ET AL | 33% | +3.4% | $351,509,324 | +$674,150 | 252,884,406 | +0.19% | FROST PHILLIP MD ET AL | 30 Sep 2025 |
| Rubric Capital Management LP | 6% | $63,137,011 | 47,791,243 | Rubric Capital Management LP | 30 Jun 2025 | |||
| HSIAO JANE PH D | 4.5% | $50,304,970 | 35,677,284 | HSIAO JANE PH D | 02 Apr 2025 |
As of 31 Mar 2026, 229 institutional investors reported holding 200,712,854 shares of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK). This represents 26% of the company’s total 770,989,043 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) together control 23% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 6.2% | 47,791,243 | 0% | 0.67% | $54,482,017 |
| BlackRock, Inc. | 4.7% | 36,232,223 | +4% | 0% | $41,304,733 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1.9% | 14,769,719 | 0% | 0% | $16,837,480 |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.9% | 14,499,164 | 0% | 0% | $16,529,047 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.5% | 11,301,501 | +2.2% | 0% | $12,886,259 |
| STATE STREET CORP | 1.2% | 9,501,377 | +6.1% | 0% | $10,831,570 |
| GOLDMAN SACHS GROUP INC | 1% | 7,675,026 | +28% | 0% | $8,749,530 |
| UBS Group AG | 0.79% | 6,071,432 | +13% | 0% | $6,921,432 |
| Whitefort Capital Management, LP | 0.55% | 4,253,340 | 0% | 1.5% | $4,848,808 |
| NORTHERN TRUST CORP | 0.47% | 3,619,346 | +5.3% | 0% | $4,126,055 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.46% | 3,574,039 | -3.2% | 0% | $4,074,404 |
| VANGUARD FIDUCIARY TRUST CO | 0.36% | 2,742,017 | 0% | 0% | $3,125,899 |
| AWM Investment Company, Inc. | 0.27% | 2,100,000 | 0% | 0.26% | $2,394,000 |
| CITADEL ADVISORS LLC | 0.27% | 2,079,547 | -27% | 0% | $2,370,684 |
| DIMENSIONAL FUND ADVISORS LP | 0.2% | 1,560,000 | -3.2% | 0% | $1,777,117 |
| WASHINGTON GROWTH STRATEGIES LLC | 0.18% | 1,356,124 | 0% | 1% | $1,545,982 |
| Y.D. More Investments Ltd | 0.17% | 1,299,473 | -0.53% | 0.06% | $1,471,915 |
| Bank of New York Mellon Corp | 0.17% | 1,280,042 | -2.3% | 0% | $1,459,247 |
| MORGAN STANLEY | 0.16% | 1,196,087 | +30% | 0% | $1,363,539 |
| VOYA INVESTMENT MANAGEMENT LLC | 0.15% | 1,160,927 | +5.3% | 0% | $1,323,457 |
| BANK OF AMERICA CORP /DE/ | 0.15% | 1,141,849 | +85% | 0% | $1,301,709 |
| JANE STREET GROUP, LLC | 0.14% | 1,114,375 | -37% | 0% | $1,270,388 |
| PFG Investments, LLC | 0.14% | 1,112,776 | -16% | 0.06% | $1,268,565 |
| OP Asset Management Ltd | 0.14% | 1,102,254 | 0.01% | $1,256,569 | |
| Clearstead Advisors, LLC | 0.11% | 884,119 | +0.2% | 0.01% | $1,007,896 |
Institutional Holders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 200,712,854 | $228,840,801 | +$1,843,790 | $1.14 | 229 |
| 2025 Q4 | 199,275,448 | $251,138,539 | +$3,655,748 | $1.26 | 217 |
| 2025 Q3 | 195,949,910 | $303,559,853 | -$11,801,008 | $1.55 | 229 |
| 2025 Q2 | 205,024,725 | $270,648,264 | -$60,618,128 | $1.32 | 215 |
| 2025 Q1 | 241,258,198 | $400,533,423 | +$72,053,389 | $1.66 | 247 |
| 2024 Q4 | 197,412,433 | $290,239,287 | +$15,903,156 | $1.47 | 230 |
| 2024 Q3 | 186,501,814 | $277,905,256 | +$7,881,691 | $1.49 | 227 |
| 2024 Q2 | 182,107,019 | $227,651,201 | +$32,281,850 | $1.25 | 227 |
| 2024 Q1 | 158,173,650 | $189,816,225 | -$15,412,795 | $1.20 | 218 |
| 2023 Q4 | 169,846,994 | $256,508,174 | +$2,949,820 | $1.51 | 211 |
| 2023 Q3 | 167,041,124 | $267,211,525 | -$11,685,601 | $1.60 | 219 |
| 2023 Q2 | 173,057,185 | $374,930,496 | -$7,391,066 | $2.17 | 224 |
| 2023 Q1 | 177,714,344 | $259,294,407 | -$3,078,751 | $1.46 | 218 |
| 2022 Q4 | 181,496,897 | $226,809,289 | -$10,191,947 | $1.25 | 214 |
| 2022 Q3 | 186,517,226 | $352,478,417 | -$8,899,720 | $1.89 | 200 |
| 2022 Q2 | 189,691,960 | $479,863,957 | -$13,941,817 | $2.53 | 210 |
| 2022 Q1 | 194,629,054 | $670,129,008 | +$10,945,254 | $3.44 | 215 |
| 2021 Q4 | 190,116,095 | $914,661,536 | +$32,672,752 | $4.81 | 222 |
| 2021 Q3 | 183,228,658 | $668,852,368 | -$29,244,813 | $3.65 | 196 |
| 2021 Q2 | 190,948,492 | $773,257,740 | +$54,948 | $4.05 | 224 |
| 2021 Q1 | 190,493,255 | $817,110,481 | +$5,248,916 | $4.29 | 230 |
| 2020 Q4 | 187,898,643 | $742,332,468 | -$29,923,745 | $3.95 | 229 |
| 2020 Q3 | 195,530,381 | $721,219,726 | -$13,315,180 | $3.69 | 207 |
| 2020 Q2 | 199,256,349 | $679,095,576 | +$131,091,146 | $3.41 | 198 |
| 2020 Q1 | 161,765,902 | $216,744,574 | -$19,687,519 | $1.34 | 167 |
| 2019 Q4 | 176,275,051 | $259,136,088 | +$41,988,405 | $1.47 | 185 |
| 2019 Q3 | 147,149,372 | $307,565,950 | -$17,098,653 | $2.09 | 173 |
| 2019 Q2 | 154,503,483 | $376,518,250 | -$4,451,090 | $2.44 | 185 |
| 2019 Q1 | 159,227,289 | $414,802,691 | +$39,359,438 | $2.61 | 185 |
| 2018 Q4 | 142,093,268 | $427,280,395 | -$32,150,016 | $3.01 | 187 |
| 2018 Q3 | 152,164,350 | $526,449,630 | +$32,002,562 | $3.46 | 197 |
| 2018 Q2 | 140,990,937 | $662,674,682 | +$30,418,093 | $4.70 | 202 |
| 2018 Q1 | 134,703,173 | $426,973,988 | +$21,808,219 | $3.17 | 210 |
| 2017 Q4 | 130,845,894 | $641,134,531 | -$11,914,079 | $4.90 | 217 |
| 2017 Q3 | 131,515,339 | $902,006,062 | +$9,805,717 | $6.86 | 228 |
| 2017 Q2 | 127,413,444 | $838,468,204 | -$14,499,676 | $6.58 | 221 |
| 2017 Q1 | 131,302,704 | $1,050,471,050 | +$158,998,246 | $8.00 | 232 |
| 2016 Q4 | 132,543,971 | $1,235,029,545 | +$47,421,334 | $9.30 | 241 |
| 2016 Q3 | 127,239,733 | $1,345,914,777 | +$129,356,378 | $10.59 | 260 |
| 2016 Q2 | 115,306,017 | $1,077,026,990 | +$41,618,153 | $9.34 | 234 |
| 2016 Q1 | 109,453,682 | $1,136,781,775 | -$48,177,301 | $10.39 | 248 |
| 2015 Q4 | 115,548,837 | $1,161,220,963 | -$134,688,417 | $10.05 | 266 |
| 2015 Q3 | 123,052,830 | $1,034,135,480 | +$270,131,808 | $8.41 | 256 |
| 2015 Q2 | 85,374,333 | $1,372,644,135 | +$79,586,364 | $16.08 | 215 |
| 2015 Q1 | 80,721,201 | $1,142,242,411 | +$43,779,625 | $14.17 | 189 |
| 2014 Q4 | 78,028,785 | $779,583,900 | +$30,051,903 | $9.99 | 175 |
| 2014 Q3 | 74,739,528 | $635,901,500 | -$64,365,946 | $8.51 | 180 |
| 2014 Q2 | 81,806,864 | $723,162,643 | +$87,038,633 | $8.84 | 171 |
| 2014 Q1 | 72,774,020 | $678,260,259 | +$9,369,927 | $9.32 | 165 |