OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK)

CUSIP: 68375N103

Q3 2025 13F Holders as of 30 Sep 2025

Type / Class
Equity / Common Stock, par value $0.01 per share
Shares outstanding
770,989,043
Total 13F shares
195,949,910
Share change
-8,411,316
Total reported value
$303,559,853
Put/Call ratio
7.6%
Price per share
$1.55
Number of holders
229
Value change
-$11,801,008
Number of buys
102
Number of sells
66

Security key

68375N103

Report period

Q3 2025

Institutions

229

Top holders

10

Top shareholders of OPK - OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Holder Source Role / Reporting Ownership % Shares Holdings Value 12M Net Δ As of Details
Et al Phillip Frost MD
13D/G
FROST PHILLIP MD ET AL
33%
252,884,406
$351,509,324 +$674,150 30 Sep 2025
Rubric Capital Management LP
13D/G 13F
Company
6%
47,791,243
$63,137,011 $0 30 Jun 2025
Jane Ph D. Hsiao
13D/G 3/4/5
HSIAO JANE PH D · Vice Chairman & CTO, Director
4.5%
35,677,284
$50,304,970 $0 02 Apr 2025
VANGUARD GROUP INC
13F
Company
5%
38,238,714
$50,475,102 30 Jun 2025
13F
BlackRock, Inc.
13F
Company
4.1%
31,449,482
$41,513,317 30 Jun 2025
13F
GEODE CAPITAL MANAGEMENT, LLC
13F
Company
1.4%
10,424,473
$13,762,945 30 Jun 2025
13F
STATE STREET CORP
13F
Company
1.1%
8,581,840
$11,328,029 30 Jun 2025
13F
UBS Group AG
13F
Company
0.74%
5,719,632
$7,549,914 30 Jun 2025
13F
Weiss Asset Management LP
13F
Company
0.62%
4,756,992
$6,279,229 30 Jun 2025
13F
NORTHERN TRUST CORP
13F
Company
0.45%
3,482,272
$4,596,599 30 Jun 2025
13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
13F
Company
0.43%
3,350,376
$4,422,496 30 Jun 2025
13F
MARSHALL WACE, LLP
13F
Company
0.43%
3,348,166
$4,419,581 30 Jun 2025
13F
GOLDMAN SACHS GROUP INC
13F
Company
0.37%
2,820,055
$3,722,473 30 Jun 2025
13F
MORGAN STANLEY
13F
Company
0.27%
2,059,054
$2,717,953 30 Jun 2025
13F
AWM Investment Company, Inc.
13F
Company
0.26%
2,000,000
$2,640,000 30 Jun 2025
13F
DIMENSIONAL FUND ADVISORS LP
13F
Company
0.25%
1,929,683
$2,547,319 30 Jun 2025
13F
Graham Capital Management, L.P.
13F
Company
0.25%
1,911,131
$2,522,693 30 Jun 2025
13F
BANK OF AMERICA CORP /DE/
13F
Company
0.25%
1,906,839
$2,517,027 30 Jun 2025
13F
TWO SIGMA INVESTMENTS, LP
13F
Company
0.24%
1,836,747
$2,424,506 30 Jun 2025
13F
Whitefort Capital Management, LP
13F
Company
0.23%
1,774,200
$2,341,944 30 Jun 2025
13F
Y.D. More Investments Ltd
13F
Company
0.2%
1,528,899
$2,012,688 30 Jun 2025
13F
JANE STREET GROUP, LLC
13F
Company
0.18%
1,384,552
$1,827,609 30 Jun 2025
13F
Invesco Ltd.
13F
Company
0.18%
1,371,045
$1,809,780 30 Jun 2025
13F
WASHINGTON GROWTH STRATEGIES LLC
13F
Company
0.18%
1,356,124
$1,790,000 30 Jun 2025
13F
VOYA INVESTMENT MANAGEMENT LLC
13F
Company
0.17%
1,319,561
$1,741,821 30 Jun 2025
13F
PFG Investments, LLC
13F
Company
0.16%
1,265,125
$1,669,965 30 Jun 2025
13F
Bank of New York Mellon Corp
13F
Company
0.15%
1,148,906
$1,516,556 30 Jun 2025
13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
13F
Company
0.15%
1,127,476
$1,488,268 30 Jun 2025
13F
Nuveen, LLC
13F
Company
0.15%
1,126,557
$1,487,055 30 Jun 2025
13F
Tejara Capital Ltd
13F
Company
0.12%
946,090
$1,248,839 30 Jun 2025
13F
AQR CAPITAL MANAGEMENT LLC
13F
Company
0.12%
935,900
$1,235,389 30 Jun 2025
13F
Assenagon Asset Management S.A.
13F
Company
0.12%
935,100
$1,232,651 30 Jun 2025
13F
Clearstead Advisors, LLC
13F
Company
0.11%
883,042
$1,165,615 30 Jun 2025
13F
MILLENNIUM MANAGEMENT LLC
13F
Company
0.09%
695,780
$918,430 30 Jun 2025
13F
BARCLAYS PLC
13F
Company
0.09%
664,407
$877,015 30 Jun 2025
13F
TWO SIGMA ADVISERS, LP
13F
Company
0.08%
648,297
$855,752 30 Jun 2025
13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP
13F
Company
0.08%
644,670
$850,964 30 Jun 2025
13F
JPMORGAN CHASE & CO
13F
Company
0.08%
630,355
$832,068 30 Jun 2025
13F
BNP PARIBAS FINANCIAL MARKETS
13F
Company
0.08%
581,671
$767,806 30 Jun 2025
13F
Swiss National Bank
13F
Company
0.07%
577,355
$762,109 30 Jun 2025
13F
COMMONWEALTH EQUITY SERVICES, LLC
13F
Company
0.07%
554,398
$732,000 30 Jun 2025
13F
RHUMBLINE ADVISERS
13F
Company
0.07%
529,553
$698,999 30 Jun 2025
13F
ALLIANCEBERNSTEIN L.P.
13F
Company
0.06%
468,290
$618,143 30 Jun 2025
13F
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
0.06%
437,506
$578,000 30 Jun 2025
13F
Connor, Clark & Lunn Investment Management Ltd.
13F
Company
0.05%
391,664
$516,996 30 Jun 2025
13F
CAPITAL ADVISORS INC/OK
13F
Company
0.05%
370,000
$38,430 30 Jun 2025
13F
Legal & General Group Plc
13F
Company
0.05%
355,682
$469,499 30 Jun 2025
13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM
13F
Company
0.04%
324,117
$427,834 30 Jun 2025
13F
WELLS FARGO & COMPANY/MN
13F
Company
0.04%
271,094
$357,845 30 Jun 2025
13F
ROYAL BANK OF CANADA
13F
Company
0.03%
267,448
$352,000 30 Jun 2025
13F

Institutional Holders of OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) as of Q3 2025

As of 30 Sep 2025, OPKO HEALTH, INC. - Common Stock, par value $0.01 per share (OPK) was held by 229 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 195,949,910 shares. The largest 10 holders included Rubric Capital Management LP, VANGUARD GROUP INC, BlackRock, Inc., GEODE CAPITAL MANAGEMENT, LLC, STATE STREET CORP, Whitefort Capital Management, LP, UBS Group AG, CHARLES SCHWAB INVESTMENT MANAGEMENT INC, NORTHERN TRUST CORP, and AQR CAPITAL MANAGEMENT LLC. This page lists 231 institutional shareholders reporting positions in this security for the Q3 2025 filing period.
Investor Option Weight % Change % Value $ * Price Shares Share Change Activity Report Period

Compare Q3 2025 vs Q2 2025 Across Filers

Q2 2025 holders
215
Q3 2025 holders
229
Holder diff
14
Investor Q2 2025 Shares Q3 2025 Shares Share Diff Share Chg % Q2 2025 Value $ Q3 2025 Value $ Value Diff $ Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
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