LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX)

Q: What does CUSIP 528872302 represent in this 13F holders report?

CUSIP 528872302 is the security identifier for LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share used to aggregate holder disclosures.

Q: How many institutions held LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share in Q4 2015?

116 institutional investors reported LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share for Q4 2015. Use the holders table for investor-level position and value details.

CUSIP: 528872302

Q4 2015 13F Holders as of 31 Dec 2015

Type / Class: Equity / Common Stock, par value $0.001 per share
Shares outstanding: 427,442,892
Total 13F shares: 109,649,652
Share change: +3,739,598
Total reported value: $1,459,682,001
Put/Call ratio: 161%
Price per share: $13.31
Number of holders: 116
Value change: +$54,951,710
Number of buys: 58
Number of sells: 49

Quarterly Holders Quick Answers

What is CUSIP 528872302?
CUSIP 528872302 identifies LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share in SEC institutional holdings data.

Need full ownership history?
Open the full security ownership history page.

Next holder-history checks

These links keep the next click tied to holder verification, nearby quarters, or outside-13F ownership context.

Back to full security ownership history for the broader multi-quarter picture.
Latest 13F filings for newly reported positions across managers.
Latest Schedule 13D/13G reports for ownership changes outside the 13F cadence.
SEC investors directory for manager drilldown.

Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q1 2016
Previous quarter: Q3 2015

Recent filing periods for CUSIP 528872302:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of LXRX - LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Artal Group S.A.	13F	Company	13%	57,517,978	$617,743,000	—	30 Sep 2015	13F
FMR LLC	13F	Company	3.6%	15,541,961	$166,921,000	—	30 Sep 2015	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	2%	8,389,120	$90,099,000	—	30 Sep 2015	13F
Ulys, L.L.C.	13F	Individual	1%	4,321,214	$46,410,000	—	30 Sep 2015	13F
VANGUARD GROUP INC	13F	Company	0.68%	2,910,082	$31,255,000	—	30 Sep 2015	13F
STATE STREET CORP	13F	Company	0.58%	2,479,555	$26,633,000	—	30 Sep 2015	13F
BlackRock Fund Advisors	13F	Company	0.57%	2,435,049	$26,152,000	—	30 Sep 2015	13F
NEA Management Company, LLC	13F	Company	— class O/S missing	2,382,286	$25,586,000	—	30 Sep 2015	13F
BRIDGER MANAGEMENT, LLC	13F	Company	0.3%	1,292,368	$13,880,000	—	30 Sep 2015	13F
BlackRock Institutional Trust Company, N.A.	13F	Company	0.25%	1,083,213	$11,634,000	—	30 Sep 2015	13F
VOYA INVESTMENT MANAGEMENT LLC	13F	Company	0.23%	963,285	$10,345,000	—	30 Sep 2015	13F
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	13F	Company	0.18%	776,457	$8,339,000	—	30 Sep 2015	13F
BALYASNY ASSET MANAGEMENT L.P.	13F	Company	0.14%	600,951	$6,454,000	—	30 Sep 2015	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.12%	533,405	$5,729,000	—	30 Sep 2015	13F
KINGDON CAPITAL MANAGEMENT, L.L.C.	13F	Company	0.12%	525,000	$5,639,000	—	30 Sep 2015	13F
MASTERS CAPITAL MANAGEMENT LLC	13F	Company	0.12%	500,000	$5,370,000	—	30 Sep 2015	13F
NORTHERN TRUST CORP	13F	Company	0.11%	462,527	$4,968,000	—	30 Sep 2015	13F
ACUTA CAPITAL PARTNERS, LLC	13F	Company	0.09%	400,000	$4,296,000	—	30 Sep 2015	13F
Tekla Capital Management LLC	13F	Company	0.08%	353,900	$3,801,000	—	30 Sep 2015	13F
ROYCE & ASSOCIATES LP	13F	Company	0.08%	334,374	$3,591,000	—	30 Sep 2015	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.07%	319,381	$3,430,000	—	30 Sep 2015	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	0.07%	302,765	$3,251,000	—	30 Sep 2015	13F
SABBY MANAGEMENT, LLC	13F	Company	0.06%	261,595	$2,810,000	—	30 Sep 2015	13F
DEUTSCHE BANK AG\	13F	Company	0.05%	220,112	$2,362,000	—	30 Sep 2015	13F
Bank of New York Mellon Corp	13F	Company	0.05%	201,988	$2,169,000	—	30 Sep 2015	13F
Rhenman & Partners Asset Management AB	13F	Company	0.05%	200,000	$2,148,000	—	30 Sep 2015	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	0.04%	187,788	$2,017,000	—	30 Sep 2015	13F
NORGES BANK	13F	Company	0.04%	158,669	$1,704,000	—	30 Sep 2015	13F
OXFORD ASSET MANAGEMENT LLP	13F	Company	0.03%	147,789	$1,587,000	—	30 Sep 2015	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.03%	144,755	$1,555,000	—	30 Sep 2015	13F
BlackRock Investment Management, LLC	13F	Company	0.03%	144,663	$1,554,000	—	30 Sep 2015	13F
JPMORGAN CHASE & CO	13F	Company	0.03%	137,693	$1,479,000	—	30 Sep 2015	13F
Invesco Ltd.	13F	Company	0.03%	131,768	$1,415,000	—	30 Sep 2015	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	0.02%	93,501	$1,004,000	—	30 Sep 2015	13F
ProShare Advisors LLC	13F	Company	0.02%	82,992	$891,000	—	30 Sep 2015	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.02%	76,101	$817,000	—	30 Sep 2015	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.02%	75,575	$812,000	—	30 Sep 2015	13F
STIFEL FINANCIAL CORP	13F	Company	0.02%	68,478	$735,000	—	30 Sep 2015	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.02%	66,756	$717,000	—	30 Sep 2015	13F
Swiss National Bank	13F	Company	0.02%	66,114	$710,000	—	30 Sep 2015	13F
TOCQUEVILLE ASSET MANAGEMENT L.P.	13F	Company	0.02%	65,000	$698,000	—	30 Sep 2015	13F
Nationwide Fund Advisors	13F	Company	0.01%	62,430	$670,000	—	30 Sep 2015	13F
TEACHERS ADVISORS, LLC	13F	Company	0.01%	60,041	$645,000	—	30 Sep 2015	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.01%	59,505	$639,000	—	30 Sep 2015	13F
Deutsche Girozentrale DekaBank	13F	Individual	0.01%	52,141	$560,000	—	30 Sep 2015	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.01%	52,085	$559,000	—	30 Sep 2015	13F
CITIGROUP INC	13F	Company	0.01%	51,253	$550,000	—	30 Sep 2015	13F
RHUMBLINE ADVISERS	13F	Company	0.01%	47,723	$513,000	—	30 Sep 2015	13F
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO	13F	Company	0.01%	45,897	$493,000	—	30 Sep 2015	13F
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO	13F	Company	0.01%	35,714	$384,000	—	30 Sep 2015	13F

Institutional Holders of LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) as of Q4 2015

As of 31 Dec 2015, LEXICON PHARMACEUTICALS, INC. - Common Stock, par value $0.001 per share (LXRX) was held by 116 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 109,649,652 shares. The largest 10 holders included Artal Group S.A., FMR LLC, UBS ASSET MANAGEMENT AMERICAS INC, Ulys, L.L.C., VANGUARD GROUP INC, NEA Management Company, LLC, BlackRock Fund Advisors, BRIDGER MANAGEMENT, LLC, STATE STREET CORP, and LOOMIS SAYLES & CO L P. This page lists 116 institutional shareholders reporting positions in this security for the Q4 2015 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2015 vs Q3 2015 Across Filers

Q3 2015 holders

Q4 2015 holders

116

Holder diff

Investor	Q3 2015 Shares	Q4 2015 Shares	Share Diff	Share Chg %	Q3 2015 Value $	Q4 2015 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.