Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI)

Q: What does CUSIP 48576U106 represent in this 13F holders report?

CUSIP 48576U106 is the security identifier for KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in Q4 2018?

116 institutional investors reported KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share for Q4 2018. Use the holders table for investor-level position and value details.

CUSIP: 48576U106

Q4 2018 13F Holders as of 31 Dec 2018

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 22,242,217
Total 13F shares: 51,412,770
Share change: +8,230,538
Total reported value: $481,695,108
Put/Call ratio: 160%
Price per share: $9.37
Number of holders: 116
Value change: +$75,184,187
Number of buys: 63
Number of sells: 48

Quarterly Holders Quick Answers

What is CUSIP 48576U106?
CUSIP 48576U106 identifies KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Newer quarter: Q1 2019
Previous quarter: Q3 2018

Recent filing periods for CUSIP 48576U106:

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Top shareholders of KPTI - Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	38%	8,364,268	$142,444,000	—	30 Sep 2018	13F
Consonance Capital Management LP	13F	Company	22%	4,827,078	$82,205,000	—	30 Sep 2018	13F
Palo Alto Investors LP	13F	Company	21%	4,663,324	$79,416,000	—	30 Sep 2018	13F
BlackRock Finance, Inc.	13F	Company	19%	4,260,531	$72,556,000	—	30 Sep 2018	13F
VANGUARD GROUP INC	13F	Company	11%	2,412,882	$41,092,000	—	30 Sep 2018	13F
STATE STREET CORP	13F	Company	8.7%	1,940,703	$33,050,000	—	30 Sep 2018	13F
FRANKLIN RESOURCES INC	13F	Company	8.3%	1,840,013	$31,335,000	—	30 Sep 2018	13F
FMR LLC	13F	Company	5.6%	1,237,783	$21,079,000	—	30 Sep 2018	13F
S.c.a. Candriam	13F	Individual	4.9%	1,085,500	$18,486,000	—	30 Sep 2018	13F
Point72 Asset Management, L.P.	13F	Company	3.8%	850,493	$14,484,000	—	30 Sep 2018	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	3.8%	835,941	$14,236,000	—	30 Sep 2018	13F
EMERALD ADVISERS, LLC	13F	Company	3.1%	694,068	$11,820,000	—	30 Sep 2018	13F
EMERALD MUTUAL FUND ADVISERS TRUST	13F	Company	2.9%	647,307	$11,024,000	—	30 Sep 2018	13F
NORTHERN TRUST CORP	13F	Company	2.8%	621,727	$10,588,000	—	30 Sep 2018	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	2.4%	531,569	$9,052,000	—	30 Sep 2018	13F
TIAA CREF INVESTMENT MANAGEMENT LLC	13F	Company	2.3%	521,058	$8,874,000	—	30 Sep 2018	13F
DEERFIELD MANAGEMENT COMPANY, L.P.	13F	Company	2.1%	475,000	$8,089,000	—	30 Sep 2018	13F
Private Capital Advisors, Inc.	13F	Company	2.1%	473,901	$8,071,000	—	30 Sep 2018	13F
Schonfeld Strategic Advisors LLC	13F	Company	1.9%	418,100	$7,121,000	—	30 Sep 2018	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	1.8%	398,957	$6,794,000	—	30 Sep 2018	13F
DEUTSCHE BANK AG\	13F	Company	1.6%	346,570	$5,901,000	—	30 Sep 2018	13F
MACQUARIE GROUP LTD	13F	Company	1.5%	338,200	$5,759,000	—	30 Sep 2018	13F
TEACHERS ADVISORS, LLC	13F	Company	1.5%	337,478	$5,747,000	—	30 Sep 2018	13F
FEDERATED HERMES, INC.	13F	Company	1.3%	295,854	$5,038,000	—	30 Sep 2018	13F
GOLDMAN SACHS GROUP INC	13F	Company	1.3%	278,877	$4,750,000	—	30 Sep 2018	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	1.2%	271,988	$4,632,000	—	30 Sep 2018	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	1.2%	260,365	$4,434,000	—	30 Sep 2018	13F
CITADEL ADVISORS LLC	13F	Company	1.1%	241,117	$4,107,000	—	30 Sep 2018	13F
TWO SIGMA ADVISERS, LP	13F	Company	1.1%	238,400	$4,060,000	—	30 Sep 2018	13F
D. E. Shaw & Co., Inc.	13F	Company	1%	223,263	$3,802,000	—	30 Sep 2018	13F
Bank of New York Mellon Corp	13F	Company	0.98%	218,594	$3,723,000	—	30 Sep 2018	13F
DOHENY ASSET MANAGEMENT /CA	13F	Company	0.97%	215,445	$3,669,000	—	30 Sep 2018	13F
FRONTIER CAPITAL MANAGEMENT CO LLC	13F	Company	0.92%	204,556	$3,484,000	—	30 Sep 2018	13F
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC	13F	Company	0.61%	135,315	$2,304,000	—	30 Sep 2018	13F
JPMORGAN CHASE & CO	13F	Company	0.55%	121,829	$2,075,000	—	30 Sep 2018	13F
Sandia Holdings, LLC	13F	Company	0.54%	119,739	$2,039,000	—	30 Sep 2018	13F
UNITED SERVICES AUTOMOBILE ASSOCIATION	13F	Company	0.51%	113,349	$1,930,000	—	30 Sep 2018	13F
Allianz Asset Management GmbH	13F	Company	0.49%	108,603	$1,850,000	—	30 Sep 2018	13F
PANAGORA ASSET MANAGEMENT INC	13F	Company	0.47%	105,172	$1,791,000	—	30 Sep 2018	13F
Capital Impact Advisors, LLC	13F	Company	0.46%	102,006	$1,744,000	—	30 Sep 2018	13F
MOORE CAPITAL MANAGEMENT, LP	13F	Company	0.45%	100,000	$1,703,000	—	30 Sep 2018	13F
MORGAN STANLEY	13F	Company	0.45%	99,198	$1,689,000	—	30 Sep 2018	13F
Swiss National Bank	13F	Company	0.38%	85,150	$1,450,000	—	30 Sep 2018	13F
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	13F	Company	0.33%	74,167	$1,263,000	—	30 Sep 2018	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.32%	70,739	$1,205,000	—	30 Sep 2018	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.32%	70,700	$1,204,000	—	30 Sep 2018	13F
BARCLAYS PLC	13F	Company	0.28%	62,387	$1,062,000	—	30 Sep 2018	13F
Spark Investment Management LLC	13F	Company	0.28%	62,100	$1,057,000	—	30 Sep 2018	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	0.28%	61,930	$1,055,000	—	30 Sep 2018	13F
NEW YORK STATE COMMON RETIREMENT FUND	13F	Company	0.24%	53,900	$918,000	—	30 Sep 2018	13F

Institutional Holders of Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) as of Q4 2018

As of 31 Dec 2018, Karyopharm Therapeutics Inc. - Common Stock, par value $0.0001 per share (KPTI) was held by 116 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 51,412,770 shares. The largest 10 holders included WELLINGTON MANAGEMENT GROUP LLP, Consonance Capital Management LP, Palo Alto Investors LP, BlackRock Inc., Ridgeback Capital Investments L.P., STATE STREET CORP, FMR LLC, FRANKLIN RESOURCES INC, Candriam Luxembourg S.C.A., and Vanguard Group Inc. This page lists 116 institutional shareholders reporting positions in this security for the Q4 2018 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q4 2018 vs Q3 2018 Across Filers

Q3 2018 holders

117

Q4 2018 holders

116

Holder diff

-1

Investor	Q3 2018 Shares	Q4 2018 Shares	Share Diff	Share Chg %	Q3 2018 Value $	Q4 2018 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.