Security key
457669307
INSMED Inc - Common Stock, par value $0.01 per share (INSM)
CUSIP: 457669307
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / Common Stock, par value $0.01 per share
- Shares outstanding
- 215,451,077
- Total 13F shares
- 212,495,856
- Share change
- -23,942
- Total reported value
- $36,991,151,224
- Put/Call ratio
- 114%
- Price per share
- $174.04
- Number of holders
- 673
- Value change
- +$198,104,753
- Number of buys
- 406
- Number of sells
- 261
Report period
Q4 2025
Institutions
673
Top holders
10
INSM full security history
Newer quarter: Q1 2026
Previous quarter: Q3 2025
INSMED Inc SEC filings
INSMED Inc company facts
Broader feeds
Reporting periods
Holder history for CUSIP 457669307
Recent filing periods:
Top shareholders of INSM - INSMED Inc - Common Stock, par value $0.01 per share (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO |
13F
13D/G
|
Company |
11%
from 13D/G
|
23,047,676
|
$3,319,096,045 | — | 30 Sep 2025 | |
| BlackRock, Inc. |
13D/G
13F
|
Company |
6.6%
|
14,121,445
|
$2,457,696,288 | +$764,349,568 | 31 Dec 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13D/G
13F
|
T. Rowe Price Associates, Inc. · Company |
3.3%
|
6,932,009
|
$998,278,616 | -$619,088,189 | 30 Sep 2025 | |
| Darwin Global Management, Ltd. |
13F
|
Company |
9.5%
|
20,457,445
|
$2,897,797,084 | — | 30 Sep 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
9.3%
|
19,935,820
|
$2,870,957,439 | — | 30 Sep 2025 | |
| FMR LLC |
13F
|
Company |
4.3%
|
9,180,963
|
$1,322,150,532 | — | 30 Sep 2025 | |
| Capital International Investors |
13F
|
Company |
3.5%
|
7,553,853
|
$1,087,830,371 | — | 30 Sep 2025 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
3.1%
|
6,703,484
|
$965,368,731 | — | 30 Sep 2025 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
2.6%
|
5,657,464
|
$814,731,390 | — | 30 Sep 2025 | |
| Artisan Partners Limited Partnership |
13F
|
Company |
2.3%
|
4,937,683
|
$711,075,729 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
1.8%
|
3,984,354
|
$573,786,820 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.7%
|
3,759,427
|
$541,500,912 | — | 30 Sep 2025 | |
| Orbis Allan Gray Ltd |
13F
|
Company |
1.5%
|
3,250,868
|
$468,157,501 | — | 30 Sep 2025 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
1.4%
|
3,084,558
|
$444,207,198 | — | 30 Sep 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
1.3%
|
2,721,879
|
$391,978,689 | — | 30 Sep 2025 | |
| Duquesne Family Office LLC |
13F
|
Company |
1.1%
|
2,423,435
|
$348,999,000 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
1.1%
|
2,336,112
|
$336,423,489 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.99%
|
2,139,725
|
$308,141,793 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.96%
|
2,057,641
|
$296,320,880 | — | 30 Sep 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.93%
|
2,003,871
|
$288,577,400 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
0.76%
|
1,646,239
|
$237,074,878 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.74%
|
1,601,806
|
$230,676,015 | — | 30 Sep 2025 | |
| Integral Health Asset Management, LLC |
13F
|
Company |
0.74%
|
1,600,000
|
$230,416,000 | — | 30 Sep 2025 | |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.72%
|
1,555,057
|
$223,943,759 | — | 30 Sep 2025 | |
| Qube Research & Technologies Ltd |
13F
|
Company |
0.72%
|
1,544,315
|
$222,396,803 | — | 30 Sep 2025 | |
| LORD, ABBETT & CO. LLC |
13F
|
Company |
0.67%
|
1,444,656
|
$208,045,000 | — | 30 Sep 2025 | |
| ROYAL BANK OF CANADA |
13F
|
Company |
0.63%
|
1,355,331
|
$195,182,000 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.58%
|
1,252,503
|
$180,372,957 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
0.56%
|
1,202,783
|
$173,210,966 | — | 30 Sep 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.53%
|
1,140,827
|
$163,936,086 | — | 30 Sep 2025 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.53%
|
1,138,901
|
$164,013,146 | — | 30 Sep 2025 | |
| Castle Hook Partners LP |
13F
|
Company |
0.51%
|
1,091,405
|
$157,173,235 | — | 30 Sep 2025 | |
| Holocene Advisors, LP |
13F
|
Company |
0.5%
|
1,083,681
|
$156,060,901 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.5%
|
1,072,942
|
$154,514,378 | — | 30 Sep 2025 | |
| Clearbridge Investments, LLC |
13F
|
Company |
0.5%
|
1,068,018
|
$153,805,255 | — | 30 Sep 2025 | |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC |
13F
|
Company |
0.48%
|
1,041,845
|
$150,036,098 | — | 30 Sep 2025 | |
| NWI MANAGEMENT LP |
13F
|
Company |
0.47%
|
1,021,000
|
$147,034,000 | — | 30 Sep 2025 | |
| EVENTIDE ASSET MANAGEMENT, LLC |
13F
|
Company |
0.47%
|
1,005,107
|
$144,735,580 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.45%
|
975,279
|
$140,449,929 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.45%
|
963,631
|
$138,772,892 | — | 30 Sep 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.41%
|
881,403
|
$126,930,846 | — | 30 Sep 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
0.4%
|
868,772
|
$125,111,856 | — | 30 Sep 2025 | |
| PRINCIPAL FINANCIAL GROUP INC |
13F
|
Company |
0.4%
|
864,294
|
$124,466,980 | — | 30 Sep 2025 | |
| FIL Ltd |
13F
|
Company |
0.4%
|
851,954
|
$122,689,896 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.38%
|
829,317
|
$119,429,941 | — | 30 Sep 2025 | |
| Fiera Capital Corp |
13F
|
Company |
0.38%
|
809,121
|
$116,521,515 | — | 30 Sep 2025 | |
| JANE STREET GROUP, LLC |
13F
|
Company |
0.37%
|
791,734
|
$114,017,613 | — | 30 Sep 2025 | |
| TWO SIGMA INVESTMENTS, LP |
13F
|
Company |
0.36%
|
772,780
|
$111,288,048 | — | 30 Sep 2025 | |
| RAYMOND JAMES FINANCIAL INC |
13F
|
Company |
0.35%
|
759,978
|
$109,444,424 | — | 30 Sep 2025 | |
| Artia Global Partners LP |
13F
|
Company |
0.34%
|
732,212
|
$105,445,850 | — | 30 Sep 2025 |
Institutional Holders of INSMED Inc - Common Stock, par value $0.01 per share (INSM) as of Q4 2025
As of 31 Dec 2025,
INSMED Inc - Common Stock, par value $0.01 per share (INSM) was held by
673 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
212,495,856 shares.
The largest 10 holders included
JPMORGAN CHASE & CO, VANGUARD GROUP INC, Darwin Global Management, Ltd., BlackRock, Inc., FMR LLC, BAKER BROS. ADVISORS LP, STATE STREET CORP, Capital International Investors, Artisan Partners Limited Partnership, and RTW INVESTMENTS, LP.
This page lists
673
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
563
Q4 2025 holders
673
Holder diff
110
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.