Security key
457669307
CUSIP: 457669307
Security key
457669307
Report period
Q3 2025
Institutions
563
Top holders
10
Broader feeds
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
13D/G
Company · T. Rowe Price Associates, Inc.
|
3.3%
from 13D/G
|
$1,130,259,000
11,230,705 shares
|
— | 30 Jun 2025 |
| Darwin Global Management, Ltd. |
13F
Company
|
8.8%
|
$1,924,596,343
19,344,621 shares
|
— | 30 Jun 2025 |
| VANGUARD GROUP INC |
13F
Company
|
8%
|
$1,775,741,675
17,644,492 shares
|
— | 30 Jun 2025 |
| JPMORGAN CHASE & CO |
13F
Company
|
7.1%
|
$1,573,647,331
15,636,399 shares
|
— | 30 Jun 2025 |
| BlackRock, Inc. |
13F
Company
|
5.1%
|
$1,121,374,365
11,142,432 shares
|
— | 30 Jun 2025 |
| BAKER BROS. ADVISORS LP |
13F
Company
|
3.5%
|
$776,226,256
7,712,900 shares
|
— | 30 Jun 2025 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
13F holder rows
Investor-level positions for this CUSIP, loaded as an interactive table.
| Investor | Option | Weight % | Change % | SEC-reported value | * Price | Shares | Share Change | Activity | Report Period |
|---|
* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.
| Investor | Q2 2025 Shares | Q3 2025 Shares | Share Diff | Share Chg % | Q2 2025 value | Q3 2025 value | Value change | Value Chg % |
|---|