| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 11% | +36% | $2,827,801,936 | +$964,491,533 | 23,014,584 | +52% | JPMORGAN CHASE & CO. | 29 Aug 2025 |
| Darwin Global Management, Ltd. | 9.7% | +13% | $2,946,076,654 | +$728,614,275 | 20,457,445 | +33% | Darwin Global Management, Ltd. | 30 Sep 2025 |
| VANGUARD GROUP INC | 10% | $1,256,380,378 | 18,218,973 | The Vanguard Group | 31 Dec 2024 | |||
| BlackRock, Inc. | 5.1% | $979,191,070 | 9,729,641 | BlackRock, Inc. | 30 Jun 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | -43% | $998,278,616 | -$619,088,189 | 6,932,009 | -38% | T. Rowe Price Associates, Inc. | 30 Sep 2025 |
As of 30 Sep 2025, 559 institutional investors reported holding 210,857,183 shares of INSMED Inc - Common Stock, par value $0.01 per share (INSM). This represents 100% of the company’s total 210,901,495 outstanding shares.
The largest institutional shareholders of INSMED Inc - Common Stock, par value $0.01 per share (INSM) together control 72% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 11% | 23,047,676 | +47% | 0.21% | $3,319,096,045 |
| Darwin Global Management, Ltd. | 9.7% | 20,457,445 | +5.8% | 81% | $2,897,797,084 |
| VANGUARD GROUP INC | 9.5% | 19,935,820 | +13% | 0.04% | $2,870,957,439 |
| BlackRock, Inc. | 5.9% | 12,364,904 | +11% | 0.03% | $1,780,669,886 |
| FMR LLC | 4.4% | 9,180,963 | +80% | 0.07% | $1,322,150,532 |
| Capital International Investors | 3.6% | 7,553,853 | +1% | 0.18% | $1,087,830,371 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | 6,931,466 | -38% | 0.11% | $998,201,000 |
| BAKER BROS. ADVISORS LP | 3.2% | 6,703,484 | -13% | 7% | $965,368,731 |
| D. E. Shaw & Co., Inc. | 2.7% | 5,657,464 | +65% | 0.66% | $814,731,390 |
| Artisan Partners Limited Partnership | 2.3% | 4,937,683 | +49% | 1% | $711,075,729 |
| STATE STREET CORP | 1.9% | 3,984,354 | -6.9% | 0.02% | $573,786,820 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.8% | 3,759,427 | +13% | 0.03% | $541,500,912 |
| Orbis Allan Gray Ltd | 1.5% | 3,250,868 | +113% | 2% | $468,157,501 |
| RTW INVESTMENTS, LP | 1.5% | 3,084,558 | 0% | 5.5% | $444,207,198 |
| AMERIPRISE FINANCIAL INC | 1.3% | 2,721,879 | -8% | 0.09% | $391,978,689 |
| Duquesne Family Office LLC | 1.1% | 2,423,435 | +7.5% | 8.9% | $348,999,000 |
| MILLENNIUM MANAGEMENT LLC | 1.1% | 2,336,112 | +10% | 0.26% | $336,423,489 |
| FRANKLIN RESOURCES INC | 1% | 2,139,725 | -9% | 0.08% | $308,141,793 |
| CITADEL ADVISORS LLC | 0.98% | 2,057,641 | +34% | 0.24% | $296,320,880 |
| Invesco Ltd. | 0.95% | 2,003,871 | +5.7% | 0.05% | $288,577,400 |
| UBS Group AG | 0.78% | 1,646,239 | +461% | 0.05% | $237,074,878 |
| BANK OF AMERICA CORP /DE/ | 0.76% | 1,601,806 | +31% | 0.02% | $230,676,015 |
| Integral Health Asset Management, LLC | 0.76% | 1,600,000 | 0% | 17% | $230,416,000 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 0.74% | 1,555,057 | -6.6% | 0.58% | $223,943,759 |
| Qube Research & Technologies Ltd | 0.73% | 1,544,315 | +43% | 0.31% | $222,396,803 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 768,615 | $134,457,650 | +$15,300,655 | $174.04 | 53 |
| 2025 Q3 | 210,857,183 | $30,322,142,306 | +$446,316,168 | $144.01 | 559 |
| 2025 Q2 | 210,375,071 | $21,148,644,502 | +$1,358,877,009 | $100.64 | 513 |
| 2025 Q1 | 197,789,205 | $15,117,195,698 | +$439,219,800 | $76.29 | 436 |
| 2024 Q4 | 192,544,545 | $13,293,875,240 | +$244,780,319 | $69.04 | 434 |
| 2024 Q3 | 188,054,494 | $13,732,893,406 | +$900,536,797 | $73.00 | 411 |
| 2024 Q2 | 175,240,601 | $11,740,766,805 | +$1,771,359,793 | $67.00 | 375 |
| 2024 Q1 | 149,761,616 | $4,062,731,615 | -$1,104,814 | $27.13 | 284 |
| 2023 Q4 | 149,731,871 | $4,640,473,667 | +$24,712,854 | $30.99 | 269 |
| 2023 Q3 | 147,357,091 | $3,720,846,962 | +$68,976,618 | $25.25 | 249 |
| 2023 Q2 | 146,401,839 | $3,087,320,690 | +$30,211,671 | $21.10 | 221 |
| 2023 Q1 | 145,487,988 | $2,479,157,946 | +$29,238,110 | $17.05 | 229 |
| 2022 Q4 | 143,724,717 | $2,870,747,315 | +$305,150,296 | $19.98 | 224 |
| 2022 Q3 | 127,521,278 | $2,746,157,362 | -$212,666,313 | $21.54 | 229 |
| 2022 Q2 | 129,190,615 | $2,547,619,834 | +$40,332,207 | $19.72 | 200 |
| 2022 Q1 | 126,479,239 | $2,971,923,265 | +$75,140,734 | $23.50 | 211 |
| 2021 Q4 | 123,318,469 | $3,358,792,092 | -$21,477,249 | $27.24 | 201 |
| 2021 Q3 | 123,374,100 | $3,397,087,163 | +$40,469,427 | $27.54 | 184 |
| 2021 Q2 | 121,478,330 | $3,456,376,124 | +$431,176,988 | $28.46 | 194 |
| 2021 Q1 | 106,602,088 | $3,631,335,192 | -$6,653,428 | $34.06 | 194 |
| 2020 Q4 | 107,580,874 | $3,581,395,788 | -$44,371,673 | $33.29 | 202 |
| 2020 Q3 | 108,714,504 | $3,495,053,137 | -$56,966,505 | $32.14 | 195 |
| 2020 Q2 | 110,715,810 | $3,045,474,894 | +$374,929,259 | $27.54 | 183 |
| 2020 Q1 | 97,643,990 | $1,563,236,817 | -$41,156,048 | $16.03 | 159 |
| 2019 Q4 | 98,329,079 | $2,348,053,229 | -$38,855,319 | $23.88 | 169 |
| 2019 Q3 | 99,035,921 | $1,747,100,746 | -$518,153,737 | $17.64 | 153 |
| 2019 Q2 | 126,395,360 | $3,235,565,096 | +$1,146,114,720 | $25.60 | 165 |
| 2019 Q1 | 82,194,605 | $2,389,348,616 | -$1,132,072 | $29.07 | 151 |
| 2018 Q4 | 82,419,564 | $1,081,320,258 | -$9,481,669 | $13.12 | 120 |
| 2018 Q3 | 80,880,640 | $1,635,485,434 | -$43,612,626 | $20.22 | 120 |
| 2018 Q2 | 82,447,822 | $1,949,876,562 | +$16,668,558 | $23.65 | 125 |
| 2018 Q1 | 81,818,840 | $1,842,516,409 | +$127,505,884 | $22.52 | 125 |
| 2017 Q4 | 75,871,275 | $2,365,660,554 | +$39,137,828 | $31.18 | 125 |
| 2017 Q3 | 73,705,883 | $2,300,049,892 | +$548,691,894 | $31.21 | 142 |
| 2017 Q2 | 56,526,187 | $969,760,710 | +$39,905,047 | $17.16 | 110 |
| 2017 Q1 | 56,998,661 | $998,026,125 | +$70,030,475 | $17.51 | 97 |
| 2016 Q4 | 57,799,199 | $764,693,750 | +$2,353,629 | $13.23 | 96 |
| 2016 Q3 | 57,474,912 | $834,201,194 | +$19,054,121 | $14.52 | 93 |
| 2016 Q2 | 56,451,131 | $556,714,141 | -$8,091,952 | $9.86 | 103 |
| 2016 Q1 | 57,022,278 | $722,305,325 | -$13,027,221 | $12.67 | 97 |
| 2015 Q4 | 56,887,745 | $1,032,792,029 | -$19,917 | $18.15 | 111 |
| 2015 Q3 | 56,767,734 | $1,053,879,972 | +$35,530,012 | $18.57 | 117 |
| 2015 Q2 | 54,410,404 | $1,328,450,938 | +$21,929,946 | $24.42 | 115 |
| 2015 Q1 | 53,709,876 | $1,117,417,187 | +$261,082,690 | $20.80 | 117 |
| 2014 Q4 | 41,928,477 | $648,686,215 | +$11,193,962 | $15.47 | 94 |
| 2014 Q3 | 41,271,273 | $538,679,902 | +$115,361,476 | $13.05 | 99 |
| 2014 Q2 | 31,011,972 | $619,318,286 | +$3,350,731 | $19.98 | 102 |
| 2014 Q1 | 30,157,438 | $573,214,840 | +$41,465,686 | $19.04 | 108 |