Latest Period
Q1 2026
Security Snapshot
INSMED Inc - Common Stock, par value $0.01 per share (INSM) Institutional Ownership
CUSIP: 457669307
13F Institutional Holders and Ownership History from Q1 2014 to Q1 2026
Institutions Reporting
663
Shares (Excl. Options)
216,270,232
Price
$163.52
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- Security type / class
- Equity / Common Stock, par value $0.01 per share
- Symbol
- INSM on Nasdaq
- All holders as of 31 Mar 2026
- Q1 2026
- Total 13F shares
- 216,270,232
- Total 13F value
- $34,949,161,288
- Portfolio coverage rank
- 0.03%
- Share change
- +3,052,437
- Value change
- +$469,180,299
- Number of holders
- 663
- Shares outstanding
- 215,451,077
- SEC-reported price per share
- $116.00
- Insider filing price
- $116.00
Latest holder snapshot
5 signals
Issuer context
Names, identifiers, and filing context for this profile.
3 identity fields
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors
Key facts
- INSM - INSMED Inc - Common Stock, par value $0.01 per share is tracked under CUSIP 457669307.
- 663 institutions reported positions in Q1 2026.
- 6 significant owners is listed from Schedule 13D/13G reporting.
Change
- Holder count moved from 673 to 663 between Q4 2025 and Q1 2026.
- SEC-reported value moved from $36,991,151,224 to $34,949,161,288.
Research use
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Evidence
Source: SEC Form 13F
Open SEC evidence
Latest holder context comes from 663 institutions filings for Q1 2026.
Security key
457669307
Latest holder period
Q1 2026
13F holders
663
13D/G owners
6
CIK / CUSIP context first
Open Q1 2026 holders
INSM full holder history
INSMED Inc SEC filings
INSMED Inc company facts
INSMED Inc insider transactions
Broader feeds
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 457669307:
13D/G owners
Significant owners
Large-stake holder rows connected to Schedule 13D/G evidence.
Rows
6
Security
INSM
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 11% | +36% | $2,827,801,936 | +$964,491,533 | 23,014,584 | +52% | JPMORGAN CHASE & CO. | 29 Aug 2025 |
| Darwin Global Management, Ltd. | 7.8% | -19% | $2,691,854,373 | -$585,019,167 | 16,805,184 | -18% | Darwin Global Management, Ltd. | 31 Mar 2026 |
| BlackRock, Inc. | 6.6% | +30% | $2,457,696,288 | +$764,349,568 | 14,121,445 | +45% | BlackRock, Inc. | 31 Dec 2025 |
| FMR LLC | 6.1% | $2,105,592,773 | 13,145,167 | FMR LLC | 31 Mar 2026 | |||
| VANGUARD CAPITAL MANAGEMENT LLC | 5.3% | $1,882,915,303 | 11,514,893 | Vanguard Capital Management | 31 Mar 2026 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | -43% | $998,278,616 | -$619,088,189 | 6,932,009 | -38% | T. Rowe Price Associates, Inc. | 30 Sep 2025 |
As of 31 Mar 2026, 663 institutional investors reported holding 216,270,232 shares of INSMED Inc - Common Stock, par value $0.01 per share (INSM). This represents 100% of the company’s total 215,451,077 outstanding shares.
13F concentration
Top 25 institutional shareholders
Largest 13F positions for this security by reported shares and value.
Top holder share
72%
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 11% | 24,150,499 | +4.1% | 0.25% | $3,702,754,770 |
| Darwin Global Management, Ltd. | 7.8% | 16,805,184 | -20% | 68% | $2,576,570,811 |
| BlackRock, Inc. | 7.7% | 16,678,146 | +11% | 0.05% | $2,727,210,442 |
| FMR LLC | 6.1% | 13,160,167 | +33% | 0.11% | $2,151,950,430 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 4.8% | 10,371,802 | 0% | 0.09% | $1,695,997,063 |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.5% | 9,642,131 | 0% | 0.04% | $1,576,681,262 |
| BAKER BROS. ADVISORS LP | 3.4% | 7,421,111 | +13% | 7% | $1,213,500,071 |
| Artisan Partners Limited Partnership | 3% | 6,527,301 | +35% | 1.7% | $1,067,344,315 |
| D. E. Shaw & Co., Inc. | 2.6% | 5,625,825 | +29% | 0.73% | $919,934,904 |
| Capital International Investors | 2.6% | 5,595,194 | +8.6% | 0.21% | $914,890,382 |
| STATE STREET CORP | 2.6% | 5,551,699 | +6.7% | 0.03% | $907,813,820 |
| RTW INVESTMENTS, LP | 2.2% | 4,842,880 | +0% | 7.9% | $791,907,738 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.1% | 4,450,389 | +3.5% | 0.05% | $733,323,353 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.4% | 3,092,807 | -23% | 0.06% | $505,737,000 |
| AMERIPRISE FINANCIAL INC | 1.4% | 3,057,718 | +55% | 0.12% | $499,999,046 |
| FRANKLIN RESOURCES INC | 1.2% | 2,617,251 | -5% | 0.1% | $427,972,899 |
| CITADEL ADVISORS LLC | 1% | 2,182,571 | +89% | 0.25% | $356,894,010 |
| Invesco Ltd. | 0.92% | 1,988,968 | -27% | 0.05% | $325,236,138 |
| Orbis Allan Gray Ltd | 0.87% | 1,872,824 | -55% | 1.3% | $306,244,181 |
| UBS Group AG | 0.81% | 1,737,481 | -7% | 0.05% | $284,112,894 |
| BANK OF AMERICA CORP /DE/ | 0.7% | 1,502,281 | -13% | 0.02% | $245,652,979 |
| Integral Health Asset Management, LLC | 0.7% | 1,500,000 | +20% | 13% | $245,280,000 |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 0.68% | 1,468,459 | +240% | 1% | $240,122,429 |
| SEI INVESTMENTS CO | 0.65% | 1,395,794 | +57% | 0.21% | $228,239,457 |
| Capital World Investors | 0.63% | 1,362,291 | 0.03% | $222,743,856 |
Quarter history
Institutional holders across reporting periods
Holder count, reported shares/value, and median price by quarter.
Periods
49
Latest
Q1 2026
Rows shown
1-25 of 49
| Period | 13F Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 216,270,232 | $34,949,161,288 | +$469,180,299 | $163.52 | 663 |
| 2025 Q4 | 212,495,856 | $36,991,151,224 | +$201,286,840 | $174.04 | 673 |
| 2025 Q3 | 210,868,315 | $30,324,118,550 | +$447,494,143 | $144.01 | 563 |
| 2025 Q2 | 210,375,071 | $21,148,644,502 | +$1,358,877,009 | $100.64 | 513 |
| 2025 Q1 | 197,789,205 | $15,117,195,698 | +$439,219,800 | $76.29 | 436 |
| 2024 Q4 | 192,544,545 | $13,293,875,240 | +$244,780,319 | $69.04 | 434 |
| 2024 Q3 | 188,054,494 | $13,732,893,406 | +$900,536,797 | $73.00 | 411 |
| 2024 Q2 | 175,240,601 | $11,740,766,805 | +$1,771,359,793 | $67.00 | 375 |
| 2024 Q1 | 149,761,616 | $4,062,731,615 | -$1,104,814 | $27.13 | 284 |
| 2023 Q4 | 149,731,871 | $4,640,473,667 | +$24,712,854 | $30.99 | 269 |
| 2023 Q3 | 147,357,091 | $3,720,846,962 | +$68,976,618 | $25.25 | 249 |
| 2023 Q2 | 146,401,839 | $3,087,320,690 | +$30,211,671 | $21.10 | 221 |
| 2023 Q1 | 145,487,988 | $2,479,157,946 | +$29,238,110 | $17.05 | 229 |
| 2022 Q4 | 143,724,717 | $2,870,747,315 | +$305,150,296 | $19.98 | 224 |
| 2022 Q3 | 127,521,278 | $2,746,157,362 | -$212,666,313 | $21.54 | 229 |
| 2022 Q2 | 129,190,615 | $2,547,619,834 | +$40,332,207 | $19.72 | 200 |
| 2022 Q1 | 126,479,239 | $2,971,923,265 | +$75,140,734 | $23.50 | 211 |
| 2021 Q4 | 123,318,469 | $3,358,792,092 | -$21,477,249 | $27.24 | 201 |
| 2021 Q3 | 123,374,100 | $3,397,087,163 | +$40,469,427 | $27.54 | 184 |
| 2021 Q2 | 121,478,330 | $3,456,376,124 | +$431,176,988 | $28.46 | 194 |
| 2021 Q1 | 106,602,088 | $3,631,335,192 | -$6,653,428 | $34.06 | 194 |
| 2020 Q4 | 107,580,874 | $3,581,395,788 | -$44,371,673 | $33.29 | 202 |
| 2020 Q3 | 108,714,504 | $3,495,053,137 | -$56,966,505 | $32.14 | 195 |
| 2020 Q2 | 110,715,810 | $3,045,474,894 | +$374,929,259 | $27.54 | 183 |
| 2020 Q1 | 97,643,990 | $1,563,236,817 | -$41,156,048 | $16.03 | 159 |