| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 10.8% | +36.3% | $2.83B | $964M | 23M | +51.8% | JPMORGAN CHASE & CO. | 29 Aug 2025 |
| Darwin Global Management, Ltd. | 9.7% | +13.3% | $2.95B | $729M | 20.5M | +32.9% | Darwin Global Management, Ltd. | 30 Sep 2025 |
| VANGUARD GROUP INC | 10.18% | $1.26B | 18.2M | The Vanguard Group | 31 Dec 2024 | |||
| BlackRock, Inc. | 5.1% | $979M | 9.73M | BlackRock, Inc. | 30 Jun 2025 | |||
| PRICE T ROWE ASSOCIATES INC /MD/ | 3.3% | -43.3% | $998M | -$619M | 6.93M | -38.3% | T. Rowe Price Associates, Inc. | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 211M | $30.3B | +$445M | $144.01 | 556 |
| 2025 Q2 | 210M | $21.1B | +$1.36B | $100.64 | 513 |
| 2025 Q1 | 198M | $15.1B | +$439M | $76.29 | 436 |
| 2024 Q4 | 193M | $13.3B | +$245M | $69.04 | 434 |
| 2024 Q3 | 188M | $13.7B | +$901M | $73.00 | 411 |
| 2024 Q2 | 175M | $11.7B | +$1.77B | $67.00 | 375 |
| 2024 Q1 | 150M | $4.06B | -$1.1M | $27.13 | 284 |
| 2023 Q4 | 150M | $4.64B | +$24.7M | $30.99 | 269 |
| 2023 Q3 | 147M | $3.72B | +$69M | $25.25 | 249 |
| 2023 Q2 | 146M | $3.09B | +$30.2M | $21.10 | 221 |
| 2023 Q1 | 145M | $2.48B | +$29.2M | $17.05 | 229 |
| 2022 Q4 | 144M | $2.87B | +$305M | $19.98 | 224 |
| 2022 Q3 | 128M | $2.75B | -$213M | $21.54 | 229 |
| 2022 Q2 | 129M | $2.55B | +$40.3M | $19.72 | 200 |
| 2022 Q1 | 126M | $2.97B | +$75.1M | $23.50 | 211 |
| 2021 Q4 | 123M | $3.36B | -$21.5M | $27.24 | 201 |
| 2021 Q3 | 123M | $3.4B | +$40.5M | $27.54 | 184 |
| 2021 Q2 | 121M | $3.46B | +$431M | $28.46 | 194 |
| 2021 Q1 | 107M | $3.63B | -$6.65M | $34.06 | 194 |
| 2020 Q4 | 108M | $3.58B | -$44.4M | $33.29 | 202 |
| 2020 Q3 | 109M | $3.5B | -$57M | $32.14 | 195 |
| 2020 Q2 | 111M | $3.05B | +$375M | $27.54 | 183 |
| 2020 Q1 | 97.6M | $1.56B | -$41.2M | $16.03 | 159 |
| 2019 Q4 | 98.3M | $2.35B | -$38.9M | $23.88 | 169 |
| 2019 Q3 | 99M | $1.75B | -$518M | $17.64 | 153 |
| 2019 Q2 | 126M | $3.24B | +$1.15B | $25.60 | 165 |
| 2019 Q1 | 82.2M | $2.39B | -$1.13M | $29.07 | 151 |
| 2018 Q4 | 82.4M | $1.08B | -$9.48M | $13.12 | 120 |
| 2018 Q3 | 80.9M | $1.64B | -$43.6M | $20.22 | 120 |
| 2018 Q2 | 82.4M | $1.95B | +$16.7M | $23.65 | 125 |
| 2018 Q1 | 81.8M | $1.84B | +$128M | $22.52 | 125 |
| 2017 Q4 | 75.9M | $2.37B | +$39.1M | $31.18 | 125 |
| 2017 Q3 | 73.7M | $2.3B | +$549M | $31.21 | 142 |
| 2017 Q2 | 56.5M | $970M | +$39.9M | $17.16 | 110 |
| 2017 Q1 | 57M | $998M | +$70M | $17.51 | 97 |
| 2016 Q4 | 57.8M | $765M | +$2.35M | $13.23 | 96 |
| 2016 Q3 | 57.5M | $834M | +$19.1M | $14.52 | 93 |
| 2016 Q2 | 56.5M | $557M | -$8.09M | $9.86 | 103 |
| 2016 Q1 | 57M | $722M | -$13M | $12.67 | 97 |
| 2015 Q4 | 56.9M | $1.03B | -$19.9K | $18.15 | 111 |
| 2015 Q3 | 56.8M | $1.05B | +$35.5M | $18.57 | 117 |
| 2015 Q2 | 54.4M | $1.33B | +$21.9M | $24.42 | 115 |
| 2015 Q1 | 53.7M | $1.12B | +$261M | $20.80 | 117 |
| 2014 Q4 | 41.9M | $649M | +$11.2M | $15.47 | 94 |
| 2014 Q3 | 41.3M | $539M | +$115M | $13.05 | 99 |
| 2014 Q2 | 31M | $619M | +$3.35M | $19.98 | 102 |
| 2014 Q1 | 30.2M | $573M | +$41.5M | $19.04 | 108 |