Security Snapshot

INSMED Inc - Common Stock, par value $0.01 per share (INSM) Institutional Ownership

CUSIP: 457669307

13F Institutional Holders and Ownership History from Q1 2014 to Q2 2026

Latest Period

Q2 2026

Institutions Reporting

661

Shares (Excl. Options)

223,108,503

Price

$106.62

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.02%
Share change
+2,865,954
Value change
+$93,668,798
Number of holders
661
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
214,372,100
SEC-reported price per share
$99.02
Insider filing price
$99.02
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • INSM - INSMED Inc - Common Stock, par value $0.01 per share is tracked under CUSIP 457669307.
  • 661 institutions reported positions in Q2 2026.
  • 6 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 671 to 661 between Q1 2026 and Q2 2026.
  • SEC-reported value moved from $35,371,088,878 to $23,753,413,910.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 661 institutions filings for Q2 2026.

Open SEC evidence

Security key

457669307

Latest holder period

Q2 2026

13F holders

661

13D/G owners

6

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
6
Security
INSM
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
FMR LLC 7.4% +22% $1,864,509,880 +$344,797,229 16,127,583 +23% FMR LLC 30 Jun 2026
BlackRock, Inc. 6.6% +30% $2,457,696,288 +$764,349,568 14,121,445 +45% BlackRock, Inc. 31 Dec 2025
VANGUARD CAPITAL MANAGEMENT LLC 5.3% $1,882,915,303 11,514,893 Vanguard Capital Management 31 Mar 2026
JPMORGAN CHASE & CO 4.7% -55% $1,105,183,654 -$1,348,633,593 10,365,622 -55% JPMORGAN CHASE & CO. 30 Jun 2026
PRICE T ROWE ASSOCIATES INC /MD/ 3.3% -43% $998,278,616 -$619,088,189 6,932,009 -38% T. Rowe Price Associates, Inc. 30 Sep 2025
Darwin Global Management, Ltd. 3% -60% $743,506,754 -$1,199,340,568 6,431,163 -62% Darwin Global Management, Ltd. 30 Jun 2026

As of 30 Jun 2026, 661 institutional investors reported holding 223,108,503 shares of INSMED Inc - Common Stock, par value $0.01 per share (INSM). This represents 104% of the company’s total 214,372,100 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
70%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
FMR LLC 7.5% 16,143,583 +23% 0.07% $1,721,228,828
BlackRock, Inc. 7.4% 15,807,984 -5.2% 0.03% $1,685,447,191
JPMORGAN CHASE & CO 4.9% 10,428,170 -57% 0.06% $1,092,246,620
VANGUARD PORTFOLIO MANAGEMENT LLC 4.9% 10,407,962 +0.35% 0.05% $1,109,696,908
VANGUARD CAPITAL MANAGEMENT LLC 4.6% 9,790,865 +1.5% 0.02% $1,043,902,026
BAKER BROS. ADVISORS LP 4.1% 8,796,111 +19% 4.7% $937,841,355
Capital International Investors 3.8% 8,238,124 +47% 0.18% $878,338,960
Darwin Global Management, Ltd. 3% 6,431,163 -62% 18% $673,600,013
AMERIPRISE FINANCIAL INC 2.9% 6,179,571 +102% 0.13% $658,878,001
Orbis Allan Gray Ltd 2.8% 6,076,487 +224% 2.2% $647,875,044
STATE STREET CORP 2.8% 6,052,174 +9% 0.02% $645,282,792
D. E. Shaw & Co., Inc. 2.7% 5,877,959 +4.5% 0.39% $626,707,989
Artisan Partners Limited Partnership 2.5% 5,441,718 -17% 0.95% $580,195,955
RTW INVESTMENTS, LP 2.3% 4,842,880 0% 4.4% $516,347,866
GEODE CAPITAL MANAGEMENT, LLC 2% 4,220,155 -5.2% 0.02% $448,763,113
PRICE T ROWE ASSOCIATES INC /MD/ 1.6% 3,405,290 +10% 0.04% $363,073,000
NORGES BANK 1.6% 3,377,641 0.04% $360,124,083
Jupiter Topco LLC 1.2% 2,605,181 0% 0.11% $277,779,211
UBS Group AG 1.2% 2,584,446 +49% 0.04% $275,553,633
CITADEL ADVISORS LLC 1.2% 2,556,973 +17% 0.16% $272,624,461
FRANKLIN RESOURCES INC 1.1% 2,273,222 -13% 0.05% $242,371,000
MAVERICK CAPITAL LTD 1% 2,150,762 2.1% $229,314,244
MILLENNIUM MANAGEMENT LLC 0.96% 2,048,005 +77% 0.15% $218,358,293
Qube Research & Technologies Ltd 0.78% 1,682,334 +1033% 0.2% $179,370,451
WESTFIELD CAPITAL MANAGEMENT CO LP 0.76% 1,629,561 +11% 0.57% $173,743,795

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
50
Latest
Q2 2026
Rows shown
1-25 of 50
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q2 223,108,503 $23,753,413,910 +$93,668,798 $106.62 661
2026 Q1 218,850,512 $35,371,088,878 +$548,539,245 $163.52 671
2025 Q4 212,495,904 $36,991,159,578 +$201,286,840 $174.04 674
2025 Q3 210,868,315 $30,324,118,550 +$447,494,143 $144.01 563
2025 Q2 210,375,071 $21,148,644,502 +$1,358,877,009 $100.64 513
2025 Q1 197,789,205 $15,117,195,698 +$439,219,800 $76.29 436
2024 Q4 192,544,545 $13,293,875,240 +$244,780,319 $69.04 434
2024 Q3 188,054,494 $13,732,893,406 +$900,536,797 $73.00 411
2024 Q2 175,240,601 $11,740,766,805 +$1,771,359,793 $67.00 375
2024 Q1 149,761,616 $4,062,731,615 -$1,104,814 $27.13 284
2023 Q4 149,731,871 $4,640,473,667 +$24,712,854 $30.99 269
2023 Q3 147,357,091 $3,720,846,962 +$68,976,618 $25.25 249
2023 Q2 146,401,839 $3,087,320,690 +$30,211,671 $21.10 221
2023 Q1 145,487,988 $2,479,157,946 +$29,238,110 $17.05 229
2022 Q4 143,724,717 $2,870,747,315 +$305,150,296 $19.98 224
2022 Q3 127,521,278 $2,746,157,362 -$212,666,313 $21.54 229
2022 Q2 129,190,615 $2,547,619,834 +$40,332,207 $19.72 200
2022 Q1 126,479,239 $2,971,923,265 +$75,140,734 $23.50 211
2021 Q4 123,318,469 $3,358,792,092 -$21,477,249 $27.24 201
2021 Q3 123,374,100 $3,397,087,163 +$40,469,427 $27.54 184
2021 Q2 121,478,330 $3,456,376,124 +$431,176,988 $28.46 194
2021 Q1 106,602,088 $3,631,335,192 -$6,653,428 $34.06 194
2020 Q4 107,580,874 $3,581,395,788 -$44,371,673 $33.29 202
2020 Q3 108,714,504 $3,495,053,137 -$56,966,505 $32.14 195
2020 Q2 110,715,810 $3,045,474,894 +$374,929,259 $27.54 183
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