Eton Pharmaceuticals, Inc. - Common Stock (ETON) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2018 to Q4 2025

Type / Class
Equity / Common Stock
Symbol
ETON on Nasdaq
Shares outstanding
26,828,643
Price per share
$15.47
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
15,891,317
Total reported value
$268,743,069
% of total 13F portfolios
0%
Share change
-1,814,093
Value change
-$34,730,498
Number of holders
101
Price from insider filings
$15.47
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Eton Pharmaceuticals, Inc. - Common Stock (ETON) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
EcoR1 Capital, LLC 7.7% $28,407,583 1,981,003 EcoR1 Capital, LLC 31 Dec 2024
BlackRock, Inc. 5.7% $21,807,587 1,530,357 BlackRock, Inc. 30 Jun 2025
VANGUARD GROUP INC 5% $29,207,619 1,344,115 The Vanguard Group 30 Sep 2025

As of 31 Dec 2025, 101 institutional investors reported holding 15,891,317 shares of Eton Pharmaceuticals, Inc. - Common Stock (ETON). This represents 59% of the company’s total 26,828,643 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Eton Pharmaceuticals, Inc. - Common Stock (ETON) together control 54% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Opaleye Management Inc. 11% 2,860,000 0% 6.4% $48,362,600
EcoR1 Capital, LLC 7.6% 2,030,544 0% 1.6% $34,336,499
BlackRock, Inc. 6.5% 1,738,907 +2% 0% $29,404,917
VANGUARD GROUP INC 5% 1,348,668 +0.34% 0% $22,805,976
Nantahala Capital Management, LLC 4.4% 1,175,951 0% 1.2% $19,885,331
GEODE CAPITAL MANAGEMENT, LLC 2.1% 565,051 -1.6% 0% $9,557,084
STATE STREET CORP 1.9% 501,925 +14% 0% $8,487,552
MORGAN STANLEY 1.8% 493,914 -16% 0% $8,352,085
Westside Investment Management, Inc. 1.8% 470,940 -0.34% 1.3% $7,963,285
OBERWEIS ASSET MANAGEMENT INC/ 1.6% 431,300 +124% 0.27% $7,293,283
THOMPSON SIEGEL & WALMSLEY LLC 1.5% 408,541 -2.4% 0.12% $6,908,000
BNP PARIBAS FINANCIAL MARKETS 1% 277,458 0% 0% $4,691,815
NORTHERN TRUST CORP 0.86% 231,849 -5.4% 0% $3,920,566
CANNELL CAPITAL LLC 0.81% 216,917 -52% 2.3% $3,668,066
RENAISSANCE TECHNOLOGIES LLC 0.77% 205,700 -37% 0.01% $3,478,387
GOLDMAN SACHS GROUP INC 0.73% 196,263 +3.2% 0% $3,318,807
Diametric Capital, LP 0.72% 193,155 +94% 0.88% $3,266,251
JPMORGAN CHASE & CO 0.69% 185,439 -47% 0% $3,135,773
Lumbard & Kellner, LLC 0.65% 174,944 -0.77% 1% $2,958,303
Aristides Capital LLC 0.6% 161,436 -3.7% 0.94% $2,729,883
Bank of New York Mellon Corp 0.48% 127,700 -1.1% 0% $2,159,413
UBS Group AG 0.47% 126,674 -43% 0% $2,142,058
Jefferies Financial Group Inc. 0.44% 118,300 +34% 0.02% $2,000,453
BANK OF AMERICA CORP /DE/ 0.39% 104,796 +40% 0% $1,772,100
Woodline Partners LP 0.36% 95,487 0.01% $1,614,685

Institutional Holders of Eton Pharmaceuticals, Inc. - Common Stock (ETON) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q4 15,891,317 $268,743,069 -$34,730,498 $16.91 101
2025 Q3 17,672,584 $384,025,414 +$22,957,486 $21.73 101
2025 Q2 16,549,306 $235,826,915 +$35,134,963 $14.25 85
2025 Q1 14,123,114 $183,315,077 +$11,955,184 $12.98 85
2024 Q4 13,135,396 $174,958,469 +$42,338,294 $13.32 70
2024 Q3 9,507,414 $57,043,272 +$8,311,784 $6.00 47
2024 Q2 8,228,308 $27,068,977 +$3,401,849 $3.29 44
2024 Q1 7,182,688 $26,933,962 -$87,277 $3.75 43
2023 Q4 7,158,411 $31,363,548 +$1,218,504 $4.38 55
2023 Q3 6,899,800 $28,769,681 +$3,931,364 $4.17 50
2023 Q2 5,976,427 $20,857,388 +$424,606 $3.49 33
2023 Q1 5,838,481 $22,478,563 +$148,362 $3.85 34
2022 Q4 5,937,571 $18,150,958 -$813,830 $2.82 31
2022 Q3 6,343,985 $13,321,785 +$813,651 $2.10 29
2022 Q2 5,916,510 $17,660,917 +$786,718 $2.62 28
2022 Q1 5,783,483 $27,369,526 +$1,310,432 $4.36 29
2021 Q4 5,731,001 $24,586,557 -$1,088,577 $4.29 30
2021 Q3 5,962,287 $32,572,856 -$1,717,167 $5.04 35
2021 Q2 3,148,485 $22,473,059 -$10,316,735 $6.16 42
2021 Q1 8,785,097 $67,961,804 +$530,664 $7.32 48
2020 Q4 8,725,390 $74,997,463 +$13,790,621 $8.13 45
2020 Q3 7,034,912 $59,521,869 +$2,214,437 $7.90 38
2020 Q2 6,803,798 $39,802,008 +$5,744,437 $5.45 40
2020 Q1 5,967,575 $24,469,000 +$13,430,167 $4.10 17
2019 Q4 2,623,150 $18,886,000 +$2,667,626 $7.20 13
2019 Q3 2,277,530 $14,392,000 +$3,218,363 $6.31 14
2019 Q2 1,767,833 $13,965,000 +$2,101,428 $7.90 10
2019 Q1 1,501,083 $12,008,000 +$2,806,319 $8.00 12
2018 Q4 1,151,824 $7,048,000 +$7,048,000 $6.12 11