| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 7.7% | $28,407,583 | 1,981,003 | EcoR1 Capital, LLC | 31 Dec 2024 | |||
| BlackRock, Inc. | 5.7% | $21,807,587 | 1,530,357 | BlackRock, Inc. | 30 Jun 2025 | |||
| VANGUARD GROUP INC | 5.01% | $29,207,619 | 1,344,115 | The Vanguard Group | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 17,672,584 | $384,025,414 | +$23,406,418 | $21.73 | 101 |
| 2025 Q2 | 16,549,306 | $235,826,915 | +$35,134,963 | $14.25 | 85 |
| 2025 Q1 | 14,123,114 | $183,315,077 | +$11,955,184 | $12.98 | 85 |
| 2024 Q4 | 13,135,396 | $174,958,469 | +$42,338,294 | $13.32 | 70 |
| 2024 Q3 | 9,507,414 | $57,043,272 | +$8,311,784 | $6 | 47 |
| 2024 Q2 | 8,228,308 | $27,068,977 | +$3,401,849 | $3.29 | 44 |
| 2024 Q1 | 7,182,688 | $26,933,962 | -$87,277 | $3.75 | 43 |
| 2023 Q4 | 7,158,411 | $31,363,548 | +$1,218,504 | $4.38 | 55 |
| 2023 Q3 | 6,899,800 | $28,769,681 | +$3,931,364 | $4.17 | 50 |
| 2023 Q2 | 5,976,427 | $20,857,388 | +$424,606 | $3.49 | 33 |
| 2023 Q1 | 5,838,481 | $22,478,563 | +$148,362 | $3.85 | 34 |
| 2022 Q4 | 5,937,571 | $18,150,958 | -$813,830 | $2.82 | 31 |
| 2022 Q3 | 6,343,985 | $13,321,785 | +$813,651 | $2.1 | 29 |
| 2022 Q2 | 5,916,510 | $17,660,917 | +$786,718 | $2.62 | 28 |
| 2022 Q1 | 5,783,483 | $27,369,526 | +$1,310,432 | $4.36 | 29 |
| 2021 Q4 | 5,731,001 | $24,586,557 | -$1,088,577 | $4.29 | 30 |
| 2021 Q3 | 5,962,287 | $32,572,856 | -$1,717,167 | $5.04 | 35 |
| 2021 Q2 | 3,148,485 | $22,473,059 | -$10,316,735 | $6.16 | 42 |
| 2021 Q1 | 8,785,097 | $67,961,804 | +$530,664 | $7.32 | 48 |
| 2020 Q4 | 8,725,390 | $74,997,463 | +$13,790,621 | $8.13 | 45 |
| 2020 Q3 | 7,034,912 | $59,521,869 | +$2,214,437 | $7.9 | 38 |
| 2020 Q2 | 6,803,798 | $39,802,008 | +$5,744,437 | $5.45 | 40 |
| 2020 Q1 | 5,967,575 | $24,469,000 | +$13,430,167 | $4.1 | 17 |
| 2019 Q4 | 2,623,150 | $18,886,000 | +$2,667,626 | $7.2 | 13 |
| 2019 Q3 | 2,277,530 | $14,392,000 | +$3,218,363 | $6.31 | 14 |
| 2019 Q2 | 1,767,833 | $13,965,000 | +$2,101,428 | $7.9 | 10 |
| 2019 Q1 | 1,501,083 | $12,008,000 | +$2,806,319 | $8 | 12 |
| 2018 Q4 | 1,151,824 | $7,048,000 | +$7,048,000 | $6.12 | 11 |