| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| FMR LLC | 15% | +46% | $466,033,211 | +$144,432,819 | 13,957,269 | +45% | FMR LLC | 31 Mar 2025 |
| VANGUARD GROUP INC | 10% | +2% | $310,914,324 | +$7,419,559 | 9,311,600 | +2.4% | The Vanguard Group | 31 Mar 2025 |
| WELLINGTON MANAGEMENT GROUP LLP | 8.9% | +45% | $349,109,925 | +$107,235,547 | 8,381,991 | +44% | Wellington Management Group LLP | 30 Sep 2025 |
| Farallon Capital Partners, L.P. | 6% | $164,477,866 | 5,625,098 | Dapice Joshua J. | 29 Aug 2025 |
As of 30 Sep 2025, 224 institutional investors reported holding 107,702,230 shares of Crinetics Pharmaceuticals, Inc. - Common Stock (CRNX). This represents 114% of the company’s total 94,179,674 outstanding shares.
The largest institutional shareholders of Crinetics Pharmaceuticals, Inc. - Common Stock (CRNX) together control 94% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 15% | 14,187,498 | +0.44% | 0.03% | $590,909,308 |
| VANGUARD GROUP INC | 9.7% | 9,170,129 | -0.93% | 0.01% | $381,935,873 |
| WELLINGTON MANAGEMENT GROUP LLP | 8.9% | 8,381,991 | +44% | 0.06% | $349,109,926 |
| BlackRock, Inc. | 8.1% | 7,586,597 | +2.3% | 0.01% | $315,981,777 |
| Driehaus Capital Management LLC | 6.9% | 6,481,613 | +1.3% | 1.9% | $269,959,181 |
| FARALLON CAPITAL MANAGEMENT LLC | 6.1% | 5,770,098 | +24% | 1.4% | $240,324,582 |
| PRICE T ROWE ASSOCIATES INC /MD/ | 5.6% | 5,306,248 | -5.1% | 0.02% | $221,006,000 |
| EcoR1 Capital, LLC | 4.6% | 4,288,120 | 0% | 8.6% | $178,600,198 |
| JANUS HENDERSON GROUP PLC | 4.1% | 3,858,791 | +13% | 0.07% | $160,695,917 |
| Paradigm Biocapital Advisors LP | 2.7% | 2,550,774 | +8.8% | 3.1% | $106,239,737 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 2,278,830 | +3% | 0.01% | $94,926,353 |
| STATE STREET CORP | 2.3% | 2,207,707 | -32% | 0% | $91,950,997 |
| JENNISON ASSOCIATES LLC | 2.2% | 2,044,734 | +2.9% | 0.05% | $85,163,170 |
| Point72 Asset Management, L.P. | 2.1% | 2,003,333 | +0.26% | 0.18% | $83,438,803 |
| Siren, L.L.C. | 1.8% | 1,688,611 | 0% | 2.8% | $70,330,648 |
| NOVO HOLDINGS A/S | 1.7% | 1,625,000 | +4.8% | 4.4% | $67,681,250 |
| Pictet Asset Management Holding SA | 1.6% | 1,465,262 | +22% | 0.06% | $61,028,162 |
| JPMORGAN CHASE & CO | 1.3% | 1,258,722 | +279% | 0% | $52,425,771 |
| AMERICAN CENTURY COMPANIES INC | 1.2% | 1,133,535 | +34% | 0.02% | $47,211,782 |
| ORBIMED ADVISORS LLC | 1.2% | 1,099,000 | -4.4% | 1.1% | $45,773,350 |
| First Light Asset Management, LLC | 1% | 941,516 | +9% | 3.7% | $39,214,141 |
| CITADEL ADVISORS LLC | 0.94% | 884,507 | +35% | 0.03% | $36,839,717 |
| Hood River Capital Management LLC | 0.94% | 883,004 | -0.62% | 0.43% | $36,777,117 |
| RTW INVESTMENTS, LP | 0.93% | 872,387 | +87% | 0.45% | $36,334,919 |
| GW&K Investment Management, LLC | 0.9% | 850,546 | -12% | 0.31% | $35,425,000 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 748,706 | $34,852,275 | +$11,263,055 | $46.55 | 15 |
| 2025 Q3 | 107,702,230 | $4,486,005,349 | +$149,678,962 | $41.65 | 224 |
| 2025 Q2 | 104,559,713 | $3,007,383,972 | +$75,026,414 | $28.76 | 220 |
| 2025 Q1 | 101,790,412 | $3,418,305,905 | +$9,856,311 | $33.54 | 225 |
| 2024 Q4 | 99,690,161 | $5,097,004,672 | +$758,098,969 | $51.13 | 245 |
| 2024 Q3 | 84,525,573 | $4,321,960,073 | +$33,724,194 | $51.10 | 233 |
| 2024 Q2 | 82,487,807 | $3,694,594,767 | +$92,152,096 | $44.79 | 232 |
| 2024 Q1 | 80,384,076 | $3,762,661,947 | +$486,785,470 | $46.81 | 201 |
| 2023 Q4 | 70,656,199 | $2,513,959,167 | +$68,274,571 | $35.58 | 180 |
| 2023 Q3 | 68,535,017 | $2,038,114,354 | +$440,832,585 | $29.74 | 171 |
| 2023 Q2 | 54,057,835 | $974,084,774 | -$11,795,159 | $18.02 | 138 |
| 2023 Q1 | 55,062,782 | $884,310,368 | +$2,280,401 | $16.06 | 127 |
| 2022 Q4 | 54,817,398 | $1,003,122,430 | -$14,306,281 | $18.30 | 121 |
| 2022 Q3 | 51,456,378 | $1,010,816,996 | +$16,147,822 | $19.64 | 118 |
| 2022 Q2 | 50,645,843 | $944,532,132 | +$94,595,270 | $18.65 | 109 |
| 2022 Q1 | 45,482,453 | $997,426,956 | -$15,117,112 | $21.95 | 114 |
| 2021 Q4 | 44,273,322 | $1,256,550,441 | +$251,517,738 | $28.41 | 114 |
| 2021 Q3 | 33,632,624 | $708,150,662 | +$17,177,215 | $21.05 | 91 |
| 2021 Q2 | 32,726,853 | $616,933,642 | +$42,446,903 | $18.85 | 81 |
| 2021 Q1 | 30,730,499 | $465,273,247 | +$5,520,857 | $15.28 | 78 |
| 2020 Q4 | 30,426,213 | $429,299,885 | -$4,592,533 | $14.11 | 84 |
| 2020 Q3 | 30,337,604 | $475,397,972 | -$19,900,117 | $15.67 | 70 |
| 2020 Q2 | 31,451,376 | $546,085,663 | +$188,712,886 | $17.52 | 79 |
| 2020 Q1 | 20,679,487 | $303,862,789 | +$45,411,611 | $14.70 | 55 |
| 2019 Q4 | 17,526,211 | $439,727,847 | -$5,476,519 | $25.09 | 58 |
| 2019 Q3 | 15,234,699 | $229,128,583 | -$94,271,503 | $15.04 | 60 |
| 2019 Q2 | 18,931,321 | $473,283,223 | +$31,131,935 | $25.00 | 63 |
| 2019 Q1 | 17,737,322 | $403,697,060 | +$20,738,652 | $22.76 | 62 |
| 2018 Q4 | 16,786,897 | $503,433,000 | +$19,006,654 | $29.99 | 50 |
| 2018 Q3 | 16,164,902 | $463,124,000 | +$463,124,002 | $28.65 | 49 |