Security key
22663K107
CUSIP: 22663K107
Security key
22663K107
Report period
Q4 2022
Institutions
121
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
5.4%
|
5,631,958
|
$110,612,000 | — | 30 Sep 2022 | |
| PERCEPTIVE ADVISORS LLC |
3/4/5
13F
|
10%+ Owner · Company |
5.1%
from 13F
|
5,321,032
|
$200,336,855 | — | 18 Apr 2022 | |
| BlackRock Finance, Inc. |
13F
|
Company |
3.6%
|
3,752,022
|
$73,688,000 | — | 30 Sep 2022 | |
| BVF INC/IL |
13F
|
Company |
3.5%
|
3,678,947
|
$72,255,000 | — | 30 Sep 2022 | |
| ORBIMED ADVISORS LLC |
13F
|
Company |
3%
|
3,196,876
|
$62,787,000 | — | 30 Sep 2022 | |
| FMR LLC |
13F
|
Company |
2.6%
|
2,681,603
|
$52,667,000 | — | 30 Sep 2022 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
2.5%
|
2,633,011
|
$51,713,000 | — | 30 Sep 2022 | |
| VANGUARD GROUP INC |
13F
|
Company |
2.2%
|
2,356,647
|
$46,284,000 | — | 30 Sep 2022 | |
| Bain Capital Life Sciences Investors, LLC |
13F
|
Company |
2.2%
|
2,305,558
|
$45,281,000 | — | 30 Sep 2022 | |
| STATE STREET CORP |
13F
|
Company |
1.7%
|
1,808,665
|
$35,522,000 | — | 30 Sep 2022 | |
| Frazier Life Sciences Management, L.P. |
13F
|
Company |
1.3%
|
1,414,823
|
$27,787,000 | — | 30 Sep 2022 | |
| First Light Asset Management, LLC |
13F
|
Company |
1.3%
|
1,346,652
|
$26,448,000 | — | 30 Sep 2022 | |
| EcoR1 Capital, LLC |
13F
|
Company |
1.3%
|
1,330,263
|
$26,126,000 | — | 30 Sep 2022 | |
| Point72 Asset Management, L.P. |
13F
|
Company |
1.2%
|
1,310,200
|
$25,732,000 | — | 30 Sep 2022 | |
| Deep Track Capital, LP |
13F
|
Company |
1%
|
1,053,000
|
$20,681,000 | — | 30 Sep 2022 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.84%
|
883,095
|
$17,343,000 | — | 30 Sep 2022 | |
| 5AM Venture Management, LLC |
13F
|
Company |
0.82%
|
862,286
|
$16,935,000 | — | 30 Sep 2022 | |
| BAKER BROS. ADVISORS LP |
13F
|
Company |
0.7%
|
735,716
|
$14,449,000 | — | 30 Sep 2022 | |
| Opaleye Management Inc. |
13F
|
Company |
0.64%
|
671,300
|
$13,184,000 | — | 30 Sep 2022 | |
| Novo Holdings A/S |
13F
|
Company |
0.6%
|
631,627
|
$12,405,000 | — | 30 Sep 2022 | |
| SPHERA FUNDS MANAGEMENT LTD. |
13F
|
Company |
0.6%
|
626,552
|
$12,305,000 | — | 30 Sep 2022 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.51%
|
536,070
|
$10,528,000 | — | 30 Sep 2022 | |
| Paradigm Biocapital Advisors LP |
13F
|
Company |
0.49%
|
519,256
|
$10,198,000 | — | 30 Sep 2022 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.46%
|
478,382
|
$9,395,000 | — | 30 Sep 2022 | |
| BNP Paribas Asset Management Holding S.A. |
13F
|
Company |
0.43%
|
455,419
|
$8,944,000 | — | 30 Sep 2022 | |
| MPM BioImpact LLC |
13F
|
Company |
0.35%
|
364,710
|
$7,163,000 | — | 30 Sep 2022 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.33%
|
341,482
|
$6,706,000 | — | 30 Sep 2022 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.32%
|
336,190
|
$6,603,000 | — | 30 Sep 2022 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.31%
|
321,752
|
$6,319,000 | — | 30 Sep 2022 | |
| Nuveen Asset Management, LLC |
13F
|
Company |
0.28%
|
296,591
|
$5,825,000 | — | 30 Sep 2022 | |
| Walleye Capital LLC |
13F
|
Company |
0.24%
|
250,014
|
$4,910,000 | — | 30 Sep 2022 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
0.18%
|
189,848
|
$3,732,000 | — | 30 Sep 2022 | |
| FIRST MANHATTAN CO. LLC. |
13F
|
Company |
0.14%
|
152,200
|
$2,989,000 | — | 30 Sep 2022 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.14%
|
149,027
|
$2,927,000 | — | 30 Sep 2022 | |
| BANK OF MONTREAL /CAN/ |
13F
|
Company |
0.14%
|
147,000
|
$3,124,000 | — | 30 Sep 2022 | |
| New Leaf Venture Partners, L.L.C. |
13F
|
Company |
0.13%
|
141,000
|
$2,769,000 | — | 30 Sep 2022 | |
| Monarch Partners Asset Management LLC |
13F
|
Company |
0.12%
|
130,860
|
$2,570,000 | — | 30 Sep 2022 | |
| TWO SIGMA ADVISERS, LP |
13F
|
Company |
0.12%
|
128,500
|
$2,524,000 | — | 30 Sep 2022 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.12%
|
122,668
|
$2,409,000 | — | 30 Sep 2022 | |
| MORGAN STANLEY |
13F
|
Company |
0.1%
|
102,012
|
$2,004,000 | — | 30 Sep 2022 | |
| VICTORY CAPITAL MANAGEMENT INC |
13F
|
Company |
0.09%
|
99,068
|
$1,946,000 | — | 30 Sep 2022 | |
| Ensign Peak Advisors, Inc |
13F
|
Company |
0.09%
|
92,324
|
$1,813,000 | — | 30 Sep 2022 | |
| HighVista Strategies LLC |
13F
|
Company |
0.09%
|
92,047
|
$1,808,000 | — | 30 Sep 2022 | |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
13F
|
Company |
0.09%
|
90,460
|
$1,777,000 | — | 30 Sep 2022 | |
| Swiss National Bank |
13F
|
Company |
0.08%
|
88,000
|
$1,728,000 | — | 30 Sep 2022 | |
| RHUMBLINE ADVISERS |
13F
|
Company |
0.08%
|
78,995
|
$1,551,000 | — | 30 Sep 2022 | |
| Rafferty Asset Management, LLC |
13F
|
Company |
0.07%
|
75,453
|
$1,482,000 | — | 30 Sep 2022 | |
| CITIGROUP INC |
13F
|
Company |
0.07%
|
70,472
|
$1,384,000 | — | 30 Sep 2022 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
0.06%
|
61,635
|
$1,212,000 | — | 30 Sep 2022 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.06%
|
59,456
|
$1,168,000 | — | 30 Sep 2022 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q3 2022 Shares | Q4 2022 Shares | Share Diff | Share Chg % | Q3 2022 Value $ | Q4 2022 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).