Talphera, Inc. - Common Stock, $0.001 par value (TLPH) Institutional Ownership

13F Institutional Holders and Ownership History from Q4 2022 to Q3 2025

Type / Class
Equity / Common Stock, $0.001 par value
Symbol
TLPH on Nasdaq
Shares outstanding
47,566,347
Price per share
$1.10
All holders as of 30 Sep 2025
Q3 2025
Total 13F shares
17,779,695
Total reported value
$15,882,401
% of total 13F portfolios
0%
Share change
+12,497,167
Value change
+$11,174,625
Number of holders
34
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Significant Owners of Talphera, Inc. - Common Stock, $0.001 par value (TLPH) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Rosalind Advisors, Inc. 9.9% 0% $12,466,784 +$5,640,489 13,957,438 +83% Rosalind Advisors, Inc. 30 Sep 2025
CorMedix Inc. 20% $3,909,091 9,090,909 CorMedix Inc. 07 Sep 2025
HIRSCHMAN ORIN 9.8% +1% $5,127,652 +$227,653 4,661,502 +4.6% Orin Hirschman 31 Dec 2025
LYTTON LAURENCE W 8% $2,036,364 3,636,364 LYTTON LAURENCE W 10 Sep 2025
Rock Springs Capital Management LP 7.9% $1,543,350 3,589,186 Rock Springs Capital Management LP 10 Sep 2025
Nantahala Capital Management, LLC 12% $976,334 1,992,519 Nantahala Capital Management, LLC 31 Mar 2025

As of 30 Sep 2025, 34 institutional investors reported holding 17,779,695 shares of Talphera, Inc. - Common Stock, $0.001 par value (TLPH). This represents 37% of the company’s total 47,566,347 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Talphera, Inc. - Common Stock, $0.001 par value (TLPH) together control 37% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
AIGH Capital Management LLC 9.4% 4,454,545 1.4% $3,978,800
Rosalind Advisors, Inc. 9.2% 4,385,757 +119% 1.4% $3,917,358
Rock Springs Capital Management LP 7.5% 3,589,186 +1034% 0.19% $3,205,861
Nantahala Capital Management, LLC 7.3% 3,492,519 +75% 0.19% $3,119,518
Bleichroeder LP 1.9% 881,166 +107% 0.15% $787,057
VANGUARD GROUP INC 0.6% 286,229 +252% 0% $256,748
GEODE CAPITAL MANAGEMENT, LLC 0.35% 165,693 +0.18% 0% $148,698
Dauntless Investment Group, LLC 0.21% 100,000 0.23% $89,320
Values First Advisors, Inc. 0.21% 97,882 -1.3% 0.05% $87,429
BlackRock, Inc. 0.19% 91,548 0% 0% $81,771
RENAISSANCE TECHNOLOGIES LLC 0.11% 50,214 +123% 0% $44,851
Virtu Financial LLC 0.07% 32,811 0% $29,000
GROUP ONE TRADING LLC 0.06% 30,415 +202667% 0% $27,285
UBS Group AG 0.06% 27,650 +125582% 0% $24,692
Mariner, LLC 0.05% 25,000 0% $22,330
STATE STREET CORP 0.05% 22,182 0% 0% $19,899
Onyx Bridge Wealth Group LLC 0.02% 11,500 +12% 0% $10,272
NORTHERN TRUST CORP 0.02% 10,891 0% 0% $9,728
PFG Investments, LLC 0.02% 10,000 0% $8,932
Tower Research Capital LLC (TRC) 0.01% 6,161 +27% 0% $5,503
MAI Capital Management 0.01% 3,314 -5.4% 0% $2,961
Sterling Capital Management LLC 0% 2,000 0% 0% $1,786
SIMPLEX TRADING, LLC 0% 1,227 0% $1,000
NewEdge Advisors, LLC 0% 500 0% 0% $447
WELLS FARGO & COMPANY/MN 0% 483 0% 0% $431

Institutional Holders of Talphera, Inc. - Common Stock, $0.001 par value (TLPH) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2025 Q3 17,779,695 $15,882,401 +$11,174,625 $0.89 34
2025 Q2 5,282,528 $2,434,944 -$116,912 $0.46 31
2025 Q1 5,523,842 $2,735,875 +$712,867 $0.50 32
2024 Q4 4,078,353 $2,137,345 -$64,684 $0.52 34
2024 Q3 4,175,439 $3,577,199 -$153,646 $0.86 28
2024 Q2 4,348,102 $3,869,606 -$74,576 $0.89 29
2024 Q1 4,424,333 $4,557,026 +$722,371 $1.03 31
2023 Q4 4,001,941 $2,941,200 -$1,080 $0.74 31
2023 Q3 3,249,391 $1,884,806 +$1,252,404 $0.58 29
2023 Q2 1,055,164 $1,170,342 +$18,838 $1.11 25
2023 Q1 1,096,573 $720,947 -$934,994 $0.66 30
2022 Q4 1,452,729 $3,282,858 +$3,282,858 $2.26 32