Insider Transactions Reported by 13 Insiders of Eikon Therapeutics, Inc.

Symbol: EIKN on Nasdaq
Location: Millbrae, CA

Quick Takeaways

EIKN - Eikon Therapeutics, Inc. has 13 insiders with reported activity on this page.
No net insider buy/sell flow is currently reported for the last year.
Recent transaction rows are available for direct filing-level review.

What Changed

No meaningful buy/sell imbalance is currently visible in the one-year window.
Activity will update as new Forms 3/4/5 are filed.

Why This Matters

This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.

Source Evidence

Filed on Form 4

Issuer insider activity is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Insider trading overview

Last 12 months

Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 19 May 2025.

Buys

Shares: 0

Insiders: 0

Sells

Shares: 0

Insiders: 0

Net

Shares: 0

Insiders: 0

Window (months)	Buy $	Sell $	Net $
0-3	$0	$0	$0
3-6	$0	$0	$0
6-9	$0	$0	$0
9-12	$0	$0	$0

Eikon Therapeutics, Inc. executives and other stock owners filed with the SEC include:

Name	Relationship	Valuation	Report Date
Roger M. Perlmutter	Chief Executive Officer and Director, Director	Mixed	02 Mar 2026
Kenneth C. Frazier	Director	Mixed	02 Mar 2026
Lux Venture Partners V, LLC	10%+ Owner	Mixed	04 Feb 2026
David W. Meline	Director	Mixed	04 Feb 2026
Roy D. Baynes	Chief Medical Officer	Mixed	02 Mar 2026
Foresite Capital Management IV, LLC	10%+ Owner	Mixed	04 Feb 2026
Robert Luther Huffines	Director	Mixed	02 Mar 2026
Leon Chen	Director	Mixed	04 Feb 2026
Column Group IV GP, LP	10%+ Owner	Mixed	06 Feb 2026
Michael A. Klobuchar	Chief Operating Officer	Mixed	02 Mar 2026
Josh Wolfe	Director, 10%+ Owner	Mixed	04 Feb 2026
Benjamin Bruno Thorner	General Counsel and Chief Business Officer	Mixed	02 Mar 2026
Alfred Lloyd Bowie Jr.	Chief Financial Officer	Mixed	02 Mar 2026

Top shareholders of Eikon Therapeutics, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Column Group IV GP, LP	13D/G 3/4/5	Tim Kutzkey · 10%+ Owner	12%	6,353,712	$131,204,153	$0	06 Feb 2026	13D/G 3/4/5
TCG Crossover Management, LLC	13F	Company	11%	1,473,101	$42,911,432	—	31 Mar 2026	13F
FMR LLC	13F 13D/G	Company	7.1% from 13D/G	3,836,830	$40,593,661	—	31 Mar 2026	13F 13D/G
BlackRock, Inc.	13F	Company	— mixed-class rows	3,347,230 mixed-class rows	$35,930,329	—	31 Mar 2026	13F
BlackRock Portfolio Management LLC	13D/G	—	5.5%	3,002,737	$29,456,850	$0	31 Mar 2026	13D/G
Roger M. Perlmutter	13D/G 3/4/5	PERLMUTTER ROGER M · Chief Executive Officer and Director, Director	5.2%	2,893,171	$28,555,598	$0	04 Feb 2026	13D/G 3/4/5
Innovation Endeavors III LP	13D/G	—	5%	2,723,226	$26,878,241	$0	31 Mar 2026	13D/G
MILLENNIUM MANAGEMENT LLC	13F	Company	— mixed-class rows	906,765 mixed-class rows	$23,156,184	—	31 Mar 2026	13F
Boxer Capital Management, LLC	13F	Company	5.9%	766,318	$22,322,843	—	31 Mar 2026	13F
Foresite Capital Management IV, LLC	13F 3/4/5	Company · 10%+ Owner	3.6%	1,943,682	$20,564,156	—	31 Mar 2026	13F 3/4/5
VR Adviser, LLC	13F	Company	4.8%	632,931	$18,437,280	—	31 Mar 2026	13F
Merck & Co., Inc.	13F	Company	3.1%	1,666,666	$17,633,326	—	31 Mar 2026	13F
VANGUARD CAPITAL MANAGEMENT LLC	13F	Company	— mixed-class rows	1,138,523 mixed-class rows	$15,182,230	—	31 Mar 2026	13F
Foresite Capital Management V, LLC	13F	Company	2.4%	1,318,983	$13,954,840	—	31 Mar 2026	13F
STEMPOINT CAPITAL LP	13F	Company	4%	525,639	$13,460,995	—	31 Mar 2026	13F
T. Rowe Price Investment Management, Inc.	13F	Company	2.2%	1,222,487	$12,934,000	—	31 Mar 2026	13F
Spruce Street Capital LP	13F	Company	3.3%	432,040	$12,585,325	—	31 Mar 2026	13F
Capital World Investors	13F	Company	2.1%	1,143,637	$12,099,679	—	31 Mar 2026	13F
BRAIDWELL LP	13F	Company	3%	396,100	$11,538,393	—	31 Mar 2026	13F
5AM Venture Management, LLC	13F	Company	3%	387,500	$11,287,875	—	31 Mar 2026	13F
Kalehua Capital Management LLC	13F	Company	3%	385,178	$11,220,235	—	31 Mar 2026	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	— mixed-class rows	997,549 mixed-class rows	$10,958,000	—	31 Mar 2026	13F
ALLIANCEBERNSTEIN L.P.	13F	Company	1.9%	1,022,188	$10,814,749	—	31 Mar 2026	13F
Vestal Point Capital, LP	13F	Company	2.6%	338,611	$9,863,738	—	31 Mar 2026	13F
EcoR1 Capital, LLC	13F	Company	1.3%	732,606	$7,750,971	—	31 Mar 2026	13F
Vivo Capital, LLC	13F	Company	2%	260,000	$7,573,800	—	31 Mar 2026	13F
PERCEPTIVE ADVISORS LLC	13F	Company	1.8%	229,393	$6,682,218	—	31 Mar 2026	13F
Woodline Partners LP	13F	Company	1.7%	227,848	$6,637,212	—	31 Mar 2026	13F
BALYASNY ASSET MANAGEMENT L.P.	13F	Company	1.6%	203,888	$5,939,256	—	31 Mar 2026	13F
BAKER BROS. ADVISORS LP	13F	Company	1%	555,555	$5,877,772	—	31 Mar 2026	13F
SOROS CAPITAL MANAGEMENT LLC	13F	Company	0.89%	484,672	$5,127,829	—	31 Mar 2026	13F
Ikarian Capital, LLC	13F	Company	1.3%	173,107	$5,042,607	—	31 Mar 2026	13F
ACUTA CAPITAL PARTNERS, LLC	13F	Company	1.3%	172,847	$5,035,033	—	31 Mar 2026	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	— mixed-class rows	339,780 mixed-class rows	$4,818,922	—	31 Mar 2026	13F
AMERIPRISE FINANCIAL INC	13F	Company	1.2%	159,711	$4,652,382	—	31 Mar 2026	13F
CITADEL ADVISORS LLC	13F	Company	— mixed-class rows	345,469 mixed-class rows	$4,313,012	—	31 Mar 2026	13F
SILVERARC CAPITAL MANAGEMENT, LLC	13F	Company	1.1%	144,255	$4,202,148	—	31 Mar 2026	13F
StepStone Group LP	13F	Company	0.73%	395,340	$4,182,697	—	31 Mar 2026	13F
CANADA PENSION PLAN INVESTMENT BOARD	13F	Company	0.7%	379,024	$4,010,074	—	31 Mar 2026	13F
Of The University Of California Regents	13F	Individual	1%	133,207	$3,880,320	—	31 Mar 2026	13F
FRANKLIN RESOURCES INC	13F	Company	0.64%	350,000	$3,703,000	—	31 Mar 2026	13F
General Catalyst Group Management, LLC	13F	Company	0.56%	305,233	$3,229,365	—	31 Mar 2026	13F
JANE STREET GROUP, LLC	13F	Company	— mixed-class rows	272,091 mixed-class rows	$3,010,261	—	31 Mar 2026	13F
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F	Company	0.68%	88,653	$2,582,462	—	31 Mar 2026	13F
Euclidean Capital LLC	13F	Company	0.67%	87,696	$2,554,584	—	31 Mar 2026	13F
VANGUARD FIDUCIARY TRUST CO	13F	Company	— mixed-class rows	167,344 mixed-class rows	$2,426,984	—	31 Mar 2026	13F
GOLDMAN SACHS GROUP INC	13F	Company	— mixed-class rows	155,157 mixed-class rows	$2,121,097	—	31 Mar 2026	13F
Ensign Peak Advisors, Inc	13F	Company	0.37%	200,000	$2,116,000	—	31 Mar 2026	13F
FRED ALGER MANAGEMENT, LLC	13F	Company	0.55%	71,697	$2,088,534	—	31 Mar 2026	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	0.34%	185,000	$1,957,300	—	31 Mar 2026	13F

Recent Insider Transactions by Companies or Individuals for Eikon Therapeutics, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Shares	Shares Owned	Date	Ownership
Michael A. Klobuchar	EIKN	Stock Option (Right to Buy)	Award		87,157	87,157	02 Mar 2026	Direct
Robert Luther Huffines	EIKN	Stock Option (Right to Buy)	Award		25,873	25,873	02 Mar 2026	Direct
Kenneth C. Frazier	EIKN	Stock Option (Right to Buy)	Award		25,873	25,873	02 Mar 2026	Direct
Roger M. Perlmutter	EIKN	Stock Option (Right to Buy)	Award		268,176	268,176	02 Mar 2026	Direct
Benjamin Bruno Thorner	EIKN	Stock Option (Right to Buy)	Award		67,044	67,044	02 Mar 2026	Direct
Roy D. Baynes	EIKN	Stock Option (Right to Buy)	Award		134,088	134,088	02 Mar 2026	Direct
Alfred Lloyd Bowie Jr.	EIKN	Stock Option (Right to Buy)	Award		67,044	67,044	02 Mar 2026	Direct
Roger M. Perlmutter	EIKN	Common Stock	Conversion of derivative security		284,857	284,857	06 Feb 2026	See Footnote
Roger M. Perlmutter	EIKN	Series D Preferred Stock	Conversion of derivative security	-100%	-855,512	0	06 Feb 2026	See Footnote
Roger M. Perlmutter	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-1,268,891	0	06 Feb 2026	See Footnote
Column Group IV GP, LP	EIKN	Common Stock	Purchase	91.7%	630,881	1,319,164	06 Feb 2026	By The Column Group Opportunity III, LP
Column Group IV GP, LP	EIKN	Common Stock	Purchase	49.9%	49,556	148,840	06 Feb 2026	By The Column Group IV-A, LP
Column Group IV GP, LP	EIKN	Common Stock	Purchase	50%	1,437,323	4,312,139	06 Feb 2026	By The Column Group IV, LP
Column Group IV GP, LP	EIKN	Common Stock	Conversion of derivative security		688,283	688,283	06 Feb 2026	By The Column Group Opportunity III, LP
Column Group IV GP, LP	EIKN	Common Stock	Conversion of derivative security	2861.9%	95,932	99,284	06 Feb 2026	By The Column Group IV-A, LP
Column Group IV GP, LP	EIKN	Common Stock	Conversion of derivative security	4413.7%	2,811,125	2,874,816	06 Feb 2026	By The Column Group IV, LP
Column Group IV GP, LP	EIKN	Series D Preferred Stock	Conversion of derivative security	-100%	-5,133,076	0	06 Feb 2026	By The Column Group Opportunity III, LP
Column Group IV GP, LP	EIKN	Series C-1 Preferred Stock	Conversion of derivative security	-100%	-28,229	0	06 Feb 2026	By The Column Group IV-A, LP
Column Group IV GP, LP	EIKN	Series C-1 Preferred Stock	Conversion of derivative security	-100%	-827,278	0	06 Feb 2026	By The Column Group IV, LP
Column Group IV GP, LP	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-357,216	0	06 Feb 2026	By The Column Group IV-A, LP
Column Group IV GP, LP	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-10,467,526	0	06 Feb 2026	By The Column Group IV, LP
Column Group IV GP, LP	EIKN	Series A Preferred Stock	Conversion of derivative security	-100%	-330,000	0	06 Feb 2026	By The Column Group IV-A, LP
Column Group IV GP, LP	EIKN	Series A Preferred Stock	Conversion of derivative security	-100%	-9,670,000	0	06 Feb 2026	By The Column Group IV, LP
Josh Wolfe	EIKN	Common Stock	Conversion of derivative security		5,695,010	2,387,705	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series D Preferred Stock	Conversion of derivative security	-100%	-10,266,152	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series C-1 Preferred Stock	Conversion of derivative security	-100%	-1,450,614	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series C Preferred Stock	Conversion of derivative security	-100%	-303,360	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series B-1 Preferred Stock	Conversion of derivative security	-100%	-8,815,537	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series B Preferred Stock	Conversion of derivative security	-100%	-1,327,300	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-10,309,278	0	06 Feb 2026	See footnote
Josh Wolfe	EIKN	Series A Preferred Stock	Conversion of derivative security	-100%	-10,000,000	0	06 Feb 2026	See footnote
Lux Venture Partners V, LLC	EIKN	Common Stock	Conversion of derivative security		5,695,010	2,387,705	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series D Preferred Stock	Conversion of derivative security	-100%	-10,266,152	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series C-1 Preferred Stock	Conversion of derivative security	-100%	-1,450,614	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series C Preferred Stock	Conversion of derivative security	-100%	-303,360	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series B-1 Preferred Stock	Conversion of derivative security	-100%	-8,815,537	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series B Preferred Stock	Conversion of derivative security	-100%	-1,327,300	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-10,309,278	0	06 Feb 2026	See Footnote
Lux Venture Partners V, LLC	EIKN	Series A Preferred Stock	Conversion of derivative security	-100%	-10,000,000	0	06 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Common Stock	Purchase	4.4%	55,555	1,318,983	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Common Stock	Conversion of derivative security		4,041,687	1,943,682	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series D Preferred Stock	Conversion of derivative security	-100%	-5,133,076	0	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series C-1 Preferred Stock	Conversion of derivative security	-100%	-785,611	0	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series C Preferred Stock	Conversion of derivative security	-100%	-19,001	0	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series B-1 Preferred Stock	Conversion of derivative security	-100%	-3,895,143	0	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series A-1 Preferred Stock	Conversion of derivative security	-100%	-10,309,278	0	04 Feb 2026	See Footnote
Foresite Capital Management IV, LLC	EIKN	Series A Preferred Stock	Conversion of derivative security	-100%	-10,000,000	0	04 Feb 2026	See Footnote
Kenneth C. Frazier	EIKN	Common Stock	Purchase		111,111	111,111	04 Feb 2026	Direct
Josh Wolfe	EIKN	Common Stock	Purchase		277,776	138,888	04 Feb 2026	See footnote
Lux Venture Partners V, LLC	EIKN	Common Stock	Purchase		277,776	138,888	04 Feb 2026	See Footnote

* An asterisk sign (*) next to the price indicates that the price is likely invalid.