Josh Wolfe - 04 Feb 2026 Form 4 Insider Report for Eikon Therapeutics, Inc. (EIKN)

Role: Director, 10%+ Owner
Signature: /s/ Benjamin Thorner, Attorney in Fact
Issuer symbol: EIKN
Transactions as of: 04 Feb 2026
Net transactions value: +$4,999,968
Form type: 4
Filing time: 06 Feb 2026, 18:27:59 UTC
Previous filing: 20 Jun 2023
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Wolfe Josh	Director, 10%+ Owner	C/O EIKON THERAPEUTICS, 230 HARRIET TUBMAN WAY, MILLBRAE	/s/ Benjamin Thorner, Attorney in Fact	06 Feb 2026	0001830001

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	EIKN	Common Stock	Purchase	$2,499,984	+138,888		$18.00	138,888	04 Feb 2026	See footnote	F1
transaction	EIKN	Common Stock	Purchase	$2,499,984	+138,888		$18.00	138,888	04 Feb 2026	See footnote	F2
transaction	EIKN	Common Stock	Conversion of derivative security		+2,387,705			2,387,705	06 Feb 2026	See footnote	F3, F4, F5
transaction	EIKN	Common Stock	Conversion of derivative security		+1,151,540	+829%		1,290,428	06 Feb 2026	See footnote	F1, F4, F6, F7
transaction	EIKN	Common Stock	Conversion of derivative security		+2,155,765	+1552%		2,294,653	06 Feb 2026	See footnote	F2, F6, F7, F8, F9, F10

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	EIKN	Series A Preferred Stock	Conversion of derivative security		-10,000,000	-100%		0	06 Feb 2026	Common Stock	1,340,878		See footnote	F3, F5
transaction	EIKN	Series A-1 Preferred Stock	Conversion of derivative security		-7,807,026	-100%		0	06 Feb 2026	Common Stock	1,046,827		See footnote	F4, F5
transaction	EIKN	Series A-1 Preferred Stock	Conversion of derivative security		-2,502,252	-100%		0	06 Feb 2026	Common Stock	335,521		See footnote	F1, F4
transaction	EIKN	Series B Preferred Stock	Conversion of derivative security		-796,380	-100%		0	06 Feb 2026	Common Stock	106,785		See footnote	F1, F6
transaction	EIKN	Series B Preferred Stock	Conversion of derivative security		-530,920	-100%		0	06 Feb 2026	Common Stock	71,190		See footnote	F2, F6
transaction	EIKN	Series B-1 Preferred Stock	Conversion of derivative security		-5,289,322	-100%		0	06 Feb 2026	Common Stock	709,234		See footnote	F1, F7
transaction	EIKN	Series B-1 Preferred Stock	Conversion of derivative security		-3,526,215	-100%		0	06 Feb 2026	Common Stock	472,822		See footnote	F2, F7
transaction	EIKN	Series C Preferred Stock	Conversion of derivative security		-303,360	-100%		0	06 Feb 2026	Common Stock	40,677		See footnote	F2, F8
transaction	EIKN	Series C-1 Preferred Stock	Conversion of derivative security		-1,450,614	-100%		0	06 Feb 2026	Common Stock	194,510		See footnote	F2, F9
transaction	EIKN	Series D Preferred Stock	Conversion of derivative security		-10,266,152	-100%		0	06 Feb 2026	Common Stock	1,376,566		See footnote	F2, F10

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares are held by Lux Co-Invest Opportunities II, L.P. ("LCIO II"). Lux Co-Invest Partners II, LLC ("LCIP II") is the general partner of LCIO II and exercises voting and dispositive power over the shares noted herein held by LCIO II. Peter Hebert and the Reporting Person (the "Individual Lux Managers"), are the individual managing members of LCIP II. The Individual Lux Managers, and as the sole managers of LCIP II, may be deemed to beneficially own the shares held by LCIO II. Each of LCIP II and the Individual Lux Managers disclaims beneficial ownership over these shares except to the extent of his pecuniary interest therein.
F2	These shares are held by Lux Total Opportunities, L.P. ("LTO"). Lux Total Opportunities Partners, LLC ("LTOP") is the general partner of LTO and exercises voting and dispositive power over the shares noted herein held by LTO. The Individual Lux Managers are the individual managing members of LTOP. The Individual Lux Managers, as the sole managers of LTOP, may be deemed to beneficially own the shares held by LTO. Each of LTOP and the Individual Lux Managers disclaims beneficial ownership over these shares except to the extent of their pecuniary interest therein.
F3	The Series A Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's initial public offering ("IPO") on a 1-for-7.4578 basis and had no expiration date.
F4	The Series A-1 Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.
F5	These shares are held by Lux Ventures V, L.P. ("LVV"). Lux Venture Partners V, LLC ("LVPV") is the general partner of LVV and exercises voting and dispositive power over the shares noted herein held by LVV. The Individual Lux Managers are the individual managing members of LVPV. The Individual Lux Managers, as the sole managers of LVPV, may be deemed to beneficially own the shares held by LVV. Each of LVPV and the Individual Lux Managers disclaims beneficial ownership over these shares except to the extent of their pecuniary interest therein.
F6	The Series B Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.
F7	The Series B-1 Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.
F8	The Series C Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.
F9	The Series C-1 Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.
F10	The Series D Preferred Stock converted into Common Stock immediately prior to the closing of the Issuer's IPO on a 1-for-7.4578 basis and had no expiration date.