SEC ownership of Centessa Pharmaceuticals plc

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001847903.

Comparable stake leader

Avoro Capital Advisors LLC

Disclosed value leader

Avoro Capital Advisors LLC

Comparable rows

3/14

Latest evidence

30 Jun 2026

Top shareholders Insider holders Latest transactions
Parsed ownership sources
13D/G and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
Largest SEC-reported holder
Avoro Capital Advisors LLC
Ranking: Comparable ownership first, then disclosed value
Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
3 of 14
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
Avoro Capital Advisors LLC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
30 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001847903
Issuer location
Altrincham, Cheshire, United Kingdom

Ownership snapshot

Top shareholders of Centessa Pharmaceuticals plc (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Avoro Capital Advisors LLC
Disclosed value leader
Avoro Capital Advisors LLC
Comparable rows
3/14
Latest evidence
30 Jun 2026
13D/G 3/4/5 Lead comparable stake: 7.4% 11 rows are not safely comparable across share classes. 13D/G row: Avoro Capital Advisors LLC Showing 1-8 of 14 holder rows.

Quick read

Avoro Capital Advisors LLC leads the comparable SEC ownership view at 7.4%.

3 of 14 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Avoro Capital Advisors LLC's linked filing trail.
Comparable ownership Top 3
Avoro Capital Advisors LLC 7.4%
General Atlantic Cooperatief U.A. 5%
FMR LLC 0%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 14 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Avoro Capital Advisors LLC
13D/G
13D/G
7.4%
$452,303,104
11,430,455 shares
 -$123,660,207 31 Mar 2026
General Atlantic Cooperatief U.A.
13D/G
13D/G
5%
$180,192,368
7,366,818 shares
 -$56,624,900 25 Nov 2025
FMR LLC
13D/G
13D/G
0%
$71,730
1,800 shares
 -$270,232,693 30 Jun 2026
INDEX VENTURES LIFE VI (JERSEY) L.P.
3/4/5
10%+ Owner
3/4/5
—
class O/S missing
$1,189,391
149,421 shares
 — 24 Jun 2026
GAP (Bermuda) L.P.
3/4/5
Director, 10%+ Owner
3/4/5
—
class O/S missing
—
48,000 shares
 — 22 Jun 2023
David J. Grainger
3/4/5
Chief Innovation Officer
3/4/5
—
class O/S missing
$7,882,708
990,290 shares
 — 31 Dec 2023
Antoine Yver
3/4/5
EVP & Chairman of Development
3/4/5
—
class O/S missing
$6,233,205
783,066 shares
 — 01 Jun 2023
Saurabh Saha
3/4/5
Chief Executive Officer, Director
3/4/5
—
mixed-class rows
$4,017,910
409,017 shares
mixed-class rows
 — 21 Jul 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$14,543,733.

Buys
$0
Insiders: 0
Sells
$14,543,733
Insiders: 5
Net
-$14,543,733
Shares: -542,243
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 542,243
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 139,885 $0 $4,066,501 -$4,066,501
6-9 0 233,186 $0 $6,082,721 -$6,082,721
9-12 0 169,172 $0 $4,394,510 -$4,394,510

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 39 reporting-owner rows connected to Centessa Pharmaceuticals plc. Open a relationship link for the CIK-to-CIK filing trail.

Rows
39
Largest Forms 3/4/5 holder
David J. Grainger
Net 12M change
-$14,543,732
Latest report
24 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
David J. Grainger Chief Innovation Officer $7,882,708 Mixed 31 Dec 2023
Antoine Yver EVP & Chairman of Development $6,233,205 Mixed 01 Jun 2023
Saurabh Saha Chief Executive Officer, Director $4,017,910 Mixed 21 Jul 2025
David M. Chao Chief Administrative Officer $3,936,902 Filing P/S 17 Mar 2025
Thomas Templeman Chief Technology Officer $1,498,422 Mixed 31 Mar 2023
Javad Shahidi Chief Medical Officer $1,265,099 Mixed 30 Sep 2022
INDEX VENTURES LIFE VI (JERSEY) L.P. 10%+ Owner $1,189,391 Mixed 24 Jun 2026
Harris Rotman SVP Regulatory Affairs $507,432 Filing P/S 01 Feb 2024
Aaron Kantoff Director $477,600 Mixed 18 Nov 2021
Marella Thorell Chief Accounting Officer $422,684 Mixed 21 Mar 2022
Iqbal J. Hussain Chief Legal Officer $0 -$1,436,292 -100% Mixed 24 Jun 2026
Stephen Kanes Chief Medical Officer $0 Mixed 24 Jun 2026
John J. Crowley Chief Financial Officer $0 Mixed 24 Jun 2026
Raphael Deferiere Chief Accounting Officer $0 Mixed 24 Jun 2026
Karen M. Anderson Chief People Officer $0 -$6,497,234 -100% Mixed 24 Jun 2026
Francesco de Rubertis Director $0 Mixed 24 Jun 2026
Medicxi Ventures I GP Ltd 10%+ Owner $0 Mixed 24 Jun 2026
Arjun Goyal Director $0 Mixed 24 Jun 2026
(jersey) Slp Yucca 10%+ Owner $0 Mixed 24 Jun 2026
Medicxi Co-Invest I LP 10%+ Owner $0 Mixed 24 Jun 2026

Recent insider transactions for Centessa Pharmaceuticals plc

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Medicxi Ventures Management (Jersey) Ltd CNTA Ordinary Shares Sale -100% -19,963,157 0 24 Jun 2026 See footnote
Index Ventures Life Vi (Jersey) L.P. CNTA Ordinary Shares Sale -100% -9,961,789 0 24 Jun 2026 See footnote
INDEX VENTURES LIFE VI (JERSEY) L.P. CNTA Ordinary Shares Sale -100% -9,961,789 0 24 Jun 2026 See footnote
Index Ventures Life Vi (Jersey) L.P. CNTA Ordinary Shares Sale -100% -9,961,789 0 24 Jun 2026 See footnote
Iqbal J. Hussain CNTA Ordinary Shares Disposed to Issuer -100% -5,500 0 24 Jun 2026 By spouse
Iqbal J. Hussain CNTA Ordinary Shares Disposed to Issuer -100% -117,645 0 24 Jun 2026 Direct
Iqbal J. Hussain CNTA Share Option (right to buy) Disposed to Issuer -100% -993,338 0 24 Jun 2026 Direct
Tia L. Bush CNTA Ordinary Shares Disposed to Issuer -100% -147,954 0 24 Jun 2026 Direct
Tia L. Bush CNTA Share Option (right to buy) Disposed to Issuer -100% -797,733 0 24 Jun 2026 Direct
John J. Crowley CNTA Ordinary Shares Disposed to Issuer -100% -45,000 0 24 Jun 2026 Direct
John J. Crowley CNTA Share Option (right to buy) Disposed to Issuer -100% -1,031,000 0 24 Jun 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Disposed to Issuer -100% -62,085 0 24 Jun 2026 Direct
Karen M. Anderson CNTA Share Option (right to buy) Disposed to Issuer -100% -424,260 0 24 Jun 2026 Direct
Raphael Deferiere CNTA Ordinary Shares Disposed to Issuer -100% -11,000 0 24 Jun 2026 Direct
Raphael Deferiere CNTA Share Option (right to buy) Disposed to Issuer -100% -207,000 0 24 Jun 2026 Direct
Stephen Kanes CNTA Ordinary Shares Disposed to Issuer -100% -120,000 0 24 Jun 2026 Direct
Stephen Kanes CNTA Share Option (right to buy) Disposed to Issuer -100% -500,000 0 24 Jun 2026 Direct
Mario Alberto Accardi CNTA Ordinary Shares Disposed to Issuer -100% -243,282 0 24 Jun 2026 Direct
Mario Alberto Accardi CNTA Share Option (right to buy) Disposed to Issuer -100% -566,425 0 24 Jun 2026 Direct
Francesco de Rubertis CNTA Ordinary Shares Disposed to Issuer -100% -19,963,157 0 24 Jun 2026 See footnote
Mary Lynne Hedley CNTA Share Option (right to buy) Disposed to Issuer -100% -296,474 0 24 Jun 2026 Direct
Arjun Goyal CNTA Ordinary Shares Disposed to Issuer -100% -462,585 0 24 Jun 2026 See footnote
Arjun Goyal CNTA Share Option (right to buy) Disposed to Issuer -100% -152,570 0 24 Jun 2026 Direct
Carol Stuckley CNTA Share Option (right to buy) Disposed to Issuer -100% -296,474 0 24 Jun 2026 Direct
Mathias Hukkelhoven CNTA Share Option (right to buy) Disposed to Issuer -100% -184,000 0 24 Jun 2026 Direct
Gregory M. Weinhoff CNTA Ordinary Shares Disposed to Issuer -100% -65,925 0 24 Jun 2026 Direct
Gregory M. Weinhoff CNTA Share Option (right to buy) Disposed to Issuer -100% -319,660 0 24 Jun 2026 See footnote
Gregory M. Weinhoff CNTA Share Option (right to buy) Disposed to Issuer -100% -1,193,323 0 24 Jun 2026 Direct
Brett I. W. Zbar CNTA Share Option (right to buy) Disposed to Issuer -100% -152,570 0 24 Jun 2026 Direct
Samarth Kulkarni CNTA Share Option (right to buy) Disposed to Issuer -100% -296,474 0 24 Jun 2026 Direct
Mario Alberto Accardi CNTA Ordinary Shares Tax liability -0.25% -604 243,282 01 May 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Sale -39.8% $1,237,382 $30.12 -41,076 62,085 26 Mar 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Options Exercise 66.2% 41,076 103,161 26 Mar 2026 Direct
Karen M. Anderson CNTA Share Option (right to buy) Options Exercise -32.9% -41,076 83,924 26 Mar 2026 Direct
Gregory M. Weinhoff CNTA Ordinary Shares Sale -26.7% $719,940 $30.00 -23,998 65,925 26 Mar 2026 Direct
Gregory M. Weinhoff CNTA Ordinary Shares Options Exercise 36.4% 23,998 89,923 26 Mar 2026 Direct
Gregory M. Weinhoff CNTA Share Option (right to buy) Options Exercise -43.6% -23,998 31,002 26 Mar 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Sale -13.9% $282,210 $28.10 -10,043 62,085 17 Mar 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Options Exercise 16.2% 10,043 72,128 17 Mar 2026 Direct
Karen M. Anderson CNTA Share Option (right to buy) Options Exercise -11.8% -10,043 75,000 17 Mar 2026 Direct
Karen M. Anderson CNTA Ordinary Shares Sale -51.1% $1,826,969 $28.21 -64,768 62,085 16 Mar 2026 Direct
* marks a reported price that did not pass the local price check.
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