SEC ownership of Lyell Immunopharma, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001806952.

Comparable stake leader

ARCH Venture Fund IX, L.P.

Disclosed value leader

Robert Nelsen

Comparable rows

8/50

Latest evidence

04 Nov 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
8 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
ARCH Venture Fund IX, L.P.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
04 Nov 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001806952
Issuer location
South San Francisco, CA

Ownership snapshot

Top shareholders of Lyell Immunopharma, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
ARCH Venture Fund IX, L.P.
Disclosed value leader
Robert Nelsen
Comparable rows
8/50
Latest evidence
04 Nov 2026
13D/G 3/4/5 13F Lead comparable stake: 14% 42 rows are not safely comparable across share classes. 13D/G row: ARCH Venture Fund IX, L.P. Showing 1-8 of 50 holder rows.

Quick read

ARCH Venture Fund IX, L.P. leads the comparable SEC ownership view at 14%.

8 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens ARCH Venture Fund IX, L.P.'s linked filing trail.
Comparable ownership Top 5
ARCH Venture Fund IX, L.P. 14%
Innovative Cellular Therapeutics ... 12%
Euler Fund, L.P. 6.7%
Explore Investments LLC/DE 6.6%
Gates Frontier, LLC 5.6%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
ARCH Venture Fund IX, L.P.
13D/G 3/4/5
10%+ Owner
14%
Reported 13D/G · 31 Mar 2026
$65,138,070
3,247,162 shares
-$669,012,113 31 Mar 2026
Innovative Cellular Therapeutics Holdings Ltd
13D/G 3/4/5
Innovative Cellular Therapeutics Holdings Limited · 10%+ Owner
12%
Reported 13D/G · 18 May 2026
$60,180,000
3,000,000 shares
+$22,066,000 18 May 2026
Euler Fund, L.P.
13D/G
6.7%
Reported 13D/G · 06 Mar 2026
$43,908,532
1,426,528 shares
$0 06 Mar 2026
Explore Investments LLC/DE
13D/G
Explore Investments LLC
6.6%
Reported 13D/G · 31 Mar 2026
$47,064,282
1,529,054 shares
+$15,023,410 31 Mar 2026
Gates Frontier, LLC
13D/G
5.6%
Reported 13D/G · 25 Jul 2025
$10,628,242
1,040,964 shares
$0 25 Jul 2025
BlackRock, Inc.
13F 13D/G
Company
4.5%
Reported 13D/G · 31 Dec 2024
$10,177,005
724,342 shares
— 30 Jun 2026
MWG Caph Ltd
13D/G
4.3%
Reported 13D/G · 31 Mar 2026
$31,029,810
1,008,116 shares
$0 31 Mar 2026
NEWTON (PTC) Ltd
13D/G
Newton (PTC) Limited
3.9%
Reported 13D/G · 30 Sep 2025
$12,256,220
754,698 shares
$0 30 Sep 2025
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to buying over the last 12 months. Net value: +$374,391,626.

Buys
$374,999,854
Insiders: 14
Sells
$608,228
Insiders: 7
Net
+$374,391,626
Shares: +33,442,573
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 33,473,848 Shares: 31,275
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 32,497,668 14,188 $349,999,884 $214,668 +$349,785,216
3-6 0 2,821 $0 $40,848 -$40,848
6-9 976,180 11,310 $24,999,970 $264,285 +$24,735,685
9-12 0 2,956 $0 $88,427 -$88,427

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 38 reporting-owner rows connected to Lyell Immunopharma, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
38
Largest Forms 3/4/5 holder
Robert Nelsen
Net 12M change
+$374.39MFull value: +$374,391,630 · USD · 12-month change
Latest report
04 Nov 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Robert Nelsen 10%+ Owner $123,384,690 +$24,999,992 +25% Mixed 04 Nov 2026
GSK plc 10%+ Owner $68,977,271 Mixed 21 Jun 2021
Paul L. Berns 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Fund XIII, L.P. 10%+ Owner $40,363,698 +$37,499,977 +1309% Filing P/S 04 Nov 2026
ARCH Venture Fund IX, L.P. 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
Steven Gillis 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Fund IX Overage, L.P. 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
Clinton Bybee 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
Keith Crandell 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Partners XIII, L.P. 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Partners XIII, LLC 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Partners IX, L.P. 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Partners IX Overage, L.P. 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
Kristina Burow 10%+ Owner $40,363,698 +$24,999,992 +163% Filing P/S 04 Nov 2026
ARCH Venture Partners IX, LLC 10%+ Owner $40,363,698 +$37,499,977 +1309% Filing P/S 04 Nov 2026
Innovative Cellular Therapeutics Holdings Ltd 10%+ Owner $38,988,469 -$274 -0% Mixed 27 Jul 2026
Hans Edgar Bishop Director $10,683,200 Mixed 14 Jun 2024
Richard Klausner Director $3,822,572 Mixed 10 Jun 2026
Lynn Seely President and CEO, Director $992,990 -$353,079 -26% Filing P/S 21 Aug 2026
Cathy Friedman Director $337,369 Mixed 10 Jun 2026

Recent insider transactions for Lyell Immunopharma, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 162.7% $24,999,992 $10.77 2,321,262 3,747,790 04 Nov 2026 See Footnote
Jarrad Mattieu Aguirre LYEL Common Stock Sale -2.08% -$3,642 $8.63 -422 19,857 12 Oct 2026 Direct
David Shook LYEL Common Stock Sale -2.39% -$6,350 $12.70 -500 20,423 10 Sep 2026 Direct
Jarrad Mattieu Aguirre LYEL Option (right to buy) Award 47,500 47,500 10 Sep 2026 Direct
Lynn Seely LYEL Common Stock Sale -13% -$149,013 $15.54 -9,589 63,899 21 Aug 2026 Direct
Stephen J. Hill LYEL Common Stock Sale -5.55% -$15,369 $15.54 -989 16,816 21 Aug 2026 Direct
Gary K. Lee LYEL Common Stock Sale -8.24% -$22,642 $15.54 -1,457 16,220 21 Aug 2026 Direct
Veronica Sanchez Bulis LYEL Common Stock Sale -4.03% -$8,905 $14.34 -621 14,799 10 Aug 2026 Direct
Gary K. Lee LYEL Common Stock Sale -0.74% -$1,879 $14.34 -131 17,677 10 Aug 2026 Direct
Stephen J. Hill LYEL Common Stock Sale -0.5% -$1,276 $14.34 -89 17,805 10 Aug 2026 Direct
Lynn Seely LYEL Common Stock Sale -0.53% -$5,593 $14.34 -390 73,488 10 Aug 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Other -1.56% -44,000 2,774,980 27 Jul 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Other -1.35% -38,500 2,818,980 27 Jul 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Sale -$137 $13.70 -10 2,857,480 17 Jul 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Sale -$137 $13.73 -10 2,857,490 16 Jul 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Other -2.59% -76,000 2,857,500 29 Jun 2026 Direct
Innovative Cellular Therapeutics Holdings Ltd LYEL Common Stock Other -2.22% -66,500 2,933,500 15 Jun 2026 Direct
William Jl Rieflin LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Sumant Ramachandra LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Elizabeth G. Nabel LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Richard Klausner LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Cathy Friedman LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Otis W. Brawley LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
Mark Bachleda LYEL Option (right to buy) Award 9,250 9,250 10 Jun 2026 Direct
David Shook LYEL Common Stock Sale -8.63% -$24,989 $12.64 -1,977 20,923 10 Jun 2026 Direct
Lynn Seely LYEL Common Stock Sale -0.52% -$7,337 $18.91 -388 73,878 11 May 2026 Direct
Gary K. Lee LYEL Common Stock Sale -0.72% -$2,460 $18.92 -130 17,808 11 May 2026 Direct
Stephen J. Hill LYEL Common Stock Sale -0.49% -$1,684 $18.92 -89 17,894 11 May 2026 Direct
Veronica Sanchez Bulis LYEL Common Stock Sale -1.39% -$4,103 $18.91 -217 15,420 11 May 2026 Direct
Smital Shah LYEL Option (right to buy) Award 140,000 140,000 09 Mar 2026 Direct
ARCH Venture Partners IX, LLC LYEL Common Stock Purchase 52% $12,499,985 $25.61 488,090 1,426,528 06 Mar 2026 See footnote
ARCH Venture Fund XIII, L.P. LYEL Common Stock Purchase 52% $12,499,985 $25.61 488,090 1,426,528 06 Mar 2026 See footnote
Lynn Seely LYEL Common Stock Sale -9.12% -$174,372 $23.39 -7,455 74,266 11 Feb 2026 Direct
Stephen J. Hill LYEL Common Stock Sale -6.49% -$28,910 $23.39 -1,236 17,795 11 Feb 2026 Direct
Gary K. Lee LYEL Common Stock Sale -8.98% -$39,085 $23.39 -1,671 16,938 11 Feb 2026 Direct
Stephen J. Hill LYEL Common Stock Sale -0.57% -$2,520 $23.12 -109 19,031 10 Feb 2026 Direct
Stephen J. Hill LYEL Option (right to buy) Award 65,000 65,000 10 Feb 2026 Direct
* marks a reported price that did not pass the local price check.
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