Security Snapshot

Lyell Immunopharma, Inc. - Common Stock, par value $0.0001 (LYEL) Institutional Ownership

CUSIP: 55083R203

13F Institutional Holders and Ownership History from Q2 2025 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

72

Shares (Excl. Options)

11,822,221

Price

$20.06

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+1,591,310
Value change
+$29,823,998
Number of holders
72
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
19,139,684
SEC-reported price per share
$20.06
Insider filing price
$20.06
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • LYEL - Lyell Immunopharma, Inc. - Common Stock, par value $0.0001 is tracked under CUSIP 55083R203.
  • 72 institutions reported positions in Q1 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 67 to 72 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $350,313,783 to $237,153,646.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 72 institutions filings for Q1 2026.

Open SEC evidence

Security key

55083R203

Latest holder period

Q1 2026

13F holders

72

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
LYEL
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
ARCH Venture Fund IX, L.P. 13% $44,807,053 2,759,072 ARCH Venture Fund IX, L.P. 30 Sep 2025
Innovative Cellular Therapeutics Holdings Ltd 9.8% $30,855,810 1,900,000 Innovative Cellular Therapeutics Holdings Ltd 06 Nov 2025
Foresite Capital Fund IV, L.P. 7.6% $23,622,818 1,454,616 James B. Tananbaum 30 Sep 2025
Gates Frontier, LLC 5.6% $10,628,242 1,040,964 Gates Frontier, LLC 25 Jul 2025
NEWTON (PTC) Ltd 3.9% $12,256,220 754,698 Newton (PTC) Limited 30 Sep 2025

As of 31 Mar 2026, 72 institutional investors reported holding 11,822,221 shares of Lyell Immunopharma, Inc. - Common Stock, par value $0.0001 (LYEL). This represents 62% of the company’s total 19,139,684 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
59%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
ARCH Venture Management, LLC 17% 3,247,162 +18% 9.6% $65,138,070
GSK plc 7.9% 1,512,659 0% 5.1% $30,343,940
Foresite Capital Management IV, LLC 4.2% 800,399 0% 6.8% $16,056,004
Orland Properties Ltd 3.9% 754,698 0% 5.7% $15,139,242
VANGUARD CAPITAL MANAGEMENT LLC 3.8% 718,155 0% 0% $14,406,189
Almitas Capital LLC 3% 577,807 0% 2.6% $11,590,808
Foresite Capital Management V, LLC 2.5% 477,078 0% 3.5% $9,570,185
MILLENNIUM MANAGEMENT LLC 2.4% 458,905 +682% 0.01% $9,205,634
CITADEL ADVISORS LLC 2% 381,462 +17% 0.01% $7,652,128
venBio Partners LLC 1.8% 337,697 0% 2.4% $6,774,202
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.6% 310,198 +105% 0.01% $6,222,572
Alphabet Inc. 1.5% 293,256 0% 0.15% $5,882,715
BlackRock, Inc. 1% 191,820 +5.5% 0% $3,847,910
GEODE CAPITAL MANAGEMENT, LLC 0.87% 166,980 +2.4% 0% $3,351,556
MARSHALL WACE, LLP 0.78% 148,516 +103% 0% $2,979,230
RENAISSANCE TECHNOLOGIES LLC 0.61% 116,411 +195% 0% $2,335,205
GOLDMAN SACHS GROUP INC 0.6% 114,491 +18% 0% $2,296,689
Velan Capital Investment Management LP 0.53% 102,000 1.3% $2,046,120
MIC Capital Management UK LLP 0.45% 87,028 0% 0.5% $1,745,782
VANGUARD FIDUCIARY TRUST CO 0.45% 86,925 0% 0% $1,743,716
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.45% 85,971 +0.64% 0% $1,724,578
Opaleye Management Inc. 0.41% 79,097 0.22% $1,586,686
STATE STREET CORP 0.38% 72,522 +41% 0% $1,454,791
JANE STREET GROUP, LLC 0.33% 63,893 +415% 0% $1,281,694
MORGAN STANLEY 0.29% 56,151 +31% 0% $1,126,389

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
4
Latest
Q1 2026
Rows shown
1-4 of 4
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 11,822,221 $237,153,646 +$29,823,998 $20.06 72
2025 Q4 11,405,527 $350,313,783 +$8,387,255 $30.78 67
2025 Q3 9,497,771 $154,237,794 +$48,003,669 $16.24 56
2025 Q2 6,818,719 $60,295,418 +$60,292,297 $8.84 62
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