Insider Transactions Reported by 17 Insiders of Tempus AI, Inc.

Symbol: TEM on Nasdaq
Location: Chicago, IL

Quick Takeaways

TEM - Tempus AI, Inc. has 17 insiders with reported activity on this page.
Net insider value flow over the last year: -$235,338,691.
Recent transaction rows are available for direct filing-level review.

What Changed

Buy value: ; sell value: $235,338,691.
Net share flow: -3,365,363.

Why This Matters

This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.

Source Evidence

Filed on Form 4

Issuer insider activity is sourced from SEC Forms 3, 4, and 5.

See Original Filing

Insider trading overview

Last 12 months

Net insider flow leans to selling over the last 12 months. Net value: -$235,338,691.

Buys

Shares: 0

Insiders: 0

Sells

$235,338,691

Shares: 3,365,363

Insiders: 10

Net

-$235,338,691

Shares: -3,365,363

Insiders: -10

Window (months)	Sell shares	Buy $	Sell $	Net $
0-3	409,255	$0	$21,951,137	-$21,951,137
3-6	773,433	$0	$52,950,707	-$52,950,707
6-9	1,130,532	$0	$89,561,665	-$89,561,665
9-12	1,052,143	$0	$70,875,182	-$70,875,182

Tempus AI, Inc. executives and other stock owners filed with the SEC include:

Name	Relationship	Holdings Value	Past Year Net Change	Change %	Valuation	Report Date
Eric Paul Lefkofsky	CEO and Chairman, Director, 10%+ Owner	$1,957,069,612	-$192,140,822	-8.9%	Mixed	26 Mar 2026
Red Sky Ventures LLC	10%+ Owner	$595,367,647			Filing P/S	11 Dec 2024
Bradley A. Keywell	10%+ Owner	$544,732,244			Filing P/S	15 Jan 2025
Ryan Fukushima	Chief Executive Officer, Data	$58,312,023	-$7,983,759	-12%	Mixed	19 Feb 2026
Andrew Polovin	EVP, Chief Legal Officer	$7,738,190	-$4,501,527	-37%	Filing P/S	19 Feb 2026
James William Rogers	Chief Financial Officer	$6,450,201	-$5,135,930	-44%	Filing P/S	02 Mar 2026
Peter J. Barris	Director	$6,271,092			Mixed	20 May 2025
Thomas Edward Schoenherr	CEO, Diagnostics	$6,031,354			Mixed	20 Feb 2026
Theodore Leonsis	Director	$5,958,797	-$18,571,196	-76%	Mixed	26 Aug 2025
Erik Phelps	EVP, Chief Admin. Officer	$4,713,134	-$5,410,884	-53%	Filing P/S	19 Feb 2026
Ryan M. Bartolucci	Chief Accounting Officer	$3,439,511	-$817,723	-19%	Mixed	19 Feb 2026
Wayne A.i. Frederick	Director	$1,918,084	-$283,820	-13%	Filing P/S	05 Dec 2025
Scott Gottlieb	Director	$1,891,246			Mixed	20 May 2025
Nadja Y. West	Director	$1,740,971			Mixed	20 May 2025
Eric D. Belcher	Director	$1,603,943			Mixed	20 May 2025
Jennifer A. Doudna	Director	$1,365,979	-$333,774	-20%	Filing P/S	02 Jan 2026
David R. Epstein	Director	$1,307,852	-$159,256	-11%	Filing P/S	02 Mar 2026

Top shareholders of Tempus AI, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Eric Paul Lefkofsky	13D/G 3/4/5	CEO and Chairman, Director, 10%+ Owner	24%	42,767,997	$2,923,620,275	-$143,612,055	31 Dec 2025	13D/G 3/4/5
BAILLIE GIFFORD & CO	13D/G 13F	Company	5.8%	9,692,441	$782,276,913	-$209,726,388	30 Sep 2025	13D/G 13F
VANGUARD GROUP INC	13F	Company	— mixed-class rows	13,512,418 mixed-class rows	$631,671,795	—	31 Dec 2025	13F
Red Sky Ventures LLC	3/4/5 13D/G	10%+ Owner	4.7% from 13D/G	14,610,249	$595,367,647	—	11 Dec 2024	3/4/5 13D/G
Bradley A. Keywell	3/4/5 13D/G	10%+ Owner	7.6% from 13D/G	15,218,365	$544,732,244	—	15 Jan 2025	3/4/5 13D/G
ARK Investment Management LLC	13F 13D/G	Company	5.4% from 13D/G	15,436,670 mixed-class rows	$508,992,782	—	31 Dec 2025	13F 13D/G
BlackRock, Inc.	13F	Company	— mixed-class rows	12,835,618 mixed-class rows	$486,169,570	—	31 Dec 2025	13F
GC Wealth Management RIA, LLC	13F	Company	3.9%	6,761,507	$399,266,988	—	31 Dec 2025	13F
SOFTBANK GROUP CORP.	13F	Company	3.1%	5,405,406	$319,189,224	—	31 Dec 2025	13F
JPMORGAN CHASE & CO	13F	Company	— mixed-class rows	4,936,636 mixed-class rows	$290,143,548	—	31 Dec 2025	13F
Amova Asset Management Americas, Inc.	13F	Company	— mixed-class rows	4,023,264 mixed-class rows	$211,086,588	—	31 Dec 2025	13F
Sumitomo Mitsui Trust Group, Inc.	13F	Company	— mixed-class rows	4,023,264 mixed-class rows	$211,086,588	—	31 Dec 2025	13F
MORGAN STANLEY	13F	Company	— mixed-class rows	2,307,957 mixed-class rows	$124,811,968	—	31 Dec 2025	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	— mixed-class rows	3,168,317 mixed-class rows	$120,811,359	—	31 Dec 2025	13F
Merck & Co., Inc.	13F	Company	13%	14,044,943	$111,797,746	—	31 Dec 2025	13F
FRANKLIN RESOURCES INC	13F	Company	1.1%	1,861,782	$109,938,228	—	31 Dec 2025	13F
STATE STREET CORP	13F	Company	— mixed-class rows	2,666,928 mixed-class rows	$103,807,455	—	31 Dec 2025	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	— mixed-class rows	1,623,957 mixed-class rows	$94,235,462	—	31 Dec 2025	13F
VOLORIDGE INVESTMENT MANAGEMENT, LLC	13F	Company	0.91%	1,573,530	$92,916,947	—	31 Dec 2025	13F
Alphabet Inc.	13F	Company	0.89%	1,551,102	$91,592,573	—	31 Dec 2025	13F
UBS Group AG	13F	Company	— mixed-class rows	1,790,430 mixed-class rows	$90,062,334	—	31 Dec 2025	13F
T. Rowe Price Investment Management, Inc.	13F	Company	10%	10,780,290	$85,812,000	—	31 Dec 2025	13F
D. E. Shaw & Co., Inc.	13F	Company	0.68%	1,180,315	$69,697,601	—	31 Dec 2025	13F
BANK OF AMERICA CORP /DE/	13F	Company	— mixed-class rows	1,200,522 mixed-class rows	$67,823,736	—	31 Dec 2025	13F
Lingotto Investment Management LLP	13F	Company	0.66%	1,143,526	$67,525,210	—	31 Dec 2025	13F
Lightspeed Management Company, L.L.C.	13F	Company	7.7%	8,160,734	$64,959,443	—	31 Dec 2025	13F
Ryan Fukushima	3/4/5	Chief Executive Officer, Data	0.53%	918,155	$58,312,023	-$7,983,759	19 Feb 2026	3/4/5
CITADEL ADVISORS LLC	13F	Company	— mixed-class rows	994,732 mixed-class rows	$54,030,369	—	31 Dec 2025	13F
AMERIPRISE FINANCIAL INC	13F	Company	— mixed-class rows	6,308,533 mixed-class rows	$51,181,024	—	31 Dec 2025	13F
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F	Company	— mixed-class rows	887,641 mixed-class rows	$50,833,097	—	31 Dec 2025	13F
NORGES BANK	13F	Company	0.47%	816,840	$48,234,402	—	31 Dec 2025	13F
GOLDMAN SACHS GROUP INC	13F	Company	— mixed-class rows	1,068,958 mixed-class rows	$45,624,922	—	31 Dec 2025	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	— mixed-class rows	901,438 mixed-class rows	$45,149,008	—	31 Dec 2025	13F
MARSHALL WACE, LLP	13F	Company	0.43%	738,646	$43,617,046	—	31 Dec 2025	13F
Clear Street Group Inc.	13F	Company	0.42%	723,365	$42,714,703	—	31 Dec 2025	13F
Aberdeen Group plc	13F	Company	— mixed-class rows	3,512,899 mixed-class rows	$41,399,550	—	31 Dec 2025	13F
Marex Group plc	13F	Company	0.39%	679,823	$40,143,548	—	31 Dec 2025	13F
GILDER GAGNON HOWE & CO LLC	13F	Company	0.33%	576,774	$34,058,505	—	31 Dec 2025	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	— mixed-class rows	571,830 mixed-class rows	$33,764,161	—	31 Dec 2025	13F
Legal & General Group Plc	13F	Company	— mixed-class rows	562,834 mixed-class rows	$33,001,763	—	31 Dec 2025	13F
NORTHERN TRUST CORP	13F	Company	— mixed-class rows	834,245 mixed-class rows	$31,129,407	—	31 Dec 2025	13F
FIRST TRUST ADVISORS LP	13F	Company	0.3%	521,029	$30,766,789	—	31 Dec 2025	13F
Trexquant Investment LP	13F	Company	0.29%	507,884	$29,990,550	—	31 Dec 2025	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.27%	471,334	$27,832,273	—	31 Dec 2025	13F
Qube Research & Technologies Ltd	13F	Company	0.27%	465,462	$27,485,531	—	31 Dec 2025	13F
WELLINGTON MANAGEMENT GROUP LLP	13F	Company	0.25%	432,686	$25,550,108	—	31 Dec 2025	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	— mixed-class rows	1,666,495 mixed-class rows	$24,399,000	—	31 Dec 2025	13F
AIGH Capital Management LLC	13F	Company	2.7%	2,900,000	$23,084,000	—	31 Dec 2025	13F
CAPITAL FUND MANAGEMENT S.A.	13F	Company	0.22%	386,595	$22,828,434	—	31 Dec 2025	13F
MASSACHUSETTS FINANCIAL SERVICES CO /MA/	13F	Company	0.22%	384,491	$22,704,194	—	31 Dec 2025	13F

Recent Insider Transactions by Companies or Individuals for Tempus AI, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Value $	* Price $	Shares	Shares Owned	Date	Ownership
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.84%	$6,168,918	$46.38	-133,000	15,789,469	26 Mar 2026	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$1,542,232	$46.38	-33,250	8,875,033	26 Mar 2026	By Gray Media, LLC
David R. Epstein	TEM	Class A Common Stock	Sale	-0.96%	$12,672	$50.69	-250	25,801	02 Mar 2026	Direct
James William Rogers	TEM	Class A Common Stock	Sale	-8.23%	$578,576	$50.69	-11,414	127,248	02 Mar 2026	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Award	13.2%			263,430	2,253,056	20 Feb 2026	Direct
Ryan M. Bartolucci	TEM	Class A Common Stock	Award	31.6%			12,998	54,157	20 Feb 2026	Direct
Andrew Polovin	TEM	Class A Common Stock	Sale	-7.94%	$660,292	$60.31	-10,949	126,918	20 Feb 2026	Direct
Andrew Polovin	TEM	Class A Common Stock	Award	38.6%			38,420	137,867	20 Feb 2026	Direct
Ryan Fukushima	TEM	Class A Common Stock	Award	10.8%			74,993	769,347	20 Feb 2026	Direct
James William Rogers	TEM	Class A Common Stock	Award	37.1%			37,496	138,662	20 Feb 2026	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.68%	$802,312	$59.05	-13,587	1,989,626	19 Feb 2026	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.83%	$7,830,159	$58.87	-133,000	15,922,469	19 Feb 2026	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$1,957,446	$58.87	-33,250	8,908,283	19 Feb 2026	By Gray Media, LLC
Erik Phelps	TEM	Class A Common Stock	Sale	-10.6%	$562,472	$59.43	-9,464	79,816	19 Feb 2026	Direct
Ryan M. Bartolucci	TEM	Class A Common Stock	Sale	-6.59%	$171,363	$59.05	-2,902	41,159	19 Feb 2026	Direct
Andrew Polovin	TEM	Class A Common Stock	Sale	-7.57%	$480,844	$59.05	-8,143	99,447	19 Feb 2026	Direct
Ryan Fukushima	TEM	Class A Common Stock	Sale	-1.36%	$566,408	$59.05	-9,592	694,354	19 Feb 2026	Direct
James William Rogers	TEM	Class A Common Stock	Sale	-9.06%	$595,460	$59.05	-10,084	101,166	19 Feb 2026	Direct
David R. Epstein	TEM	Class A Common Stock	Sale	-1.4%	$21,982	$59.41	-370	26,051	02 Feb 2026	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.82%	$8,719,372	$65.56	-133,000	16,055,469	28 Jan 2026	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$2,179,835	$65.56	-33,250	8,941,533	28 Jan 2026	By Gray Media, LLC
Ryan Fukushima	TEM	Class A Common Stock	Sale	-3.25%	$321,300	$64.26	-5,000	148,808	05 Jan 2026	By Spouse
Jennifer A. Doudna	TEM	Class A Common Stock	Sale	-5.22%	$75,212	$60.17	-1,250	22,702	02 Jan 2026	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.81%	$8,510,835	$63.99	-133,000	16,188,469	18 Dec 2025	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$2,127,643	$63.99	-33,250	8,974,783	18 Dec 2025	By Gray Media, LLC
Erik Phelps	TEM	Class A Common Stock	Sale	-1.44%	$87,781	$67.42	-1,302	89,280	16 Dec 2025	Direct
James William Rogers	TEM	Class A Common Stock	Sale	-15.2%	$1,461,479	$73.20	-19,966	111,250	11 Dec 2025	Direct
Wayne A.i. Frederick	TEM	Class A Common Stock	Sale	-12.9%	$283,820	$77.23	-3,675	24,836	05 Dec 2025	Direct
David R. Epstein	TEM	Class A Comnmon Stock	Sale	-0.94%	$18,888	$75.55	-250	26,421	01 Dec 2025	Direct
Ryan Fukushima	TEM	Class A Common Stock	Sale	-3.15%	$378,620	$75.72	-5,000	153,808	01 Dec 2025	By Spouse
Jennifer A. Doudna	TEM	Class A Common Stock	Sale	-2.74%	$51,072	$75.55	-676	23,952	01 Dec 2025	Direct
Ryan Fukushima	TEM	Class A Common Stock	Gift	-100%			-131,893	0	25 Nov 2025	By Ryan Fukushima Irrevocable Family Trust
Ryan Fukushima	TEM	Class A Common Stock	Gift	27%			33,808	158,808	25 Nov 2025	By Spouse
Ryan Fukushima	TEM	Class A Common Stock	Gift	-15.1%			-125,135	703,946	25 Nov 2025	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.8%	$9,855,300	$74.10	-133,000	16,571,469	24 Nov 2025	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$2,463,825	$74.10	-33,250	9,008,033	24 Nov 2025	By Gray Media, LLC
Andrew Polovin	TEM	Class A Common Stock	Sale	-10.7%	$965,550	$75.00	-12,874	107,590	24 Nov 2025	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.79%	$9,172,882	$68.97	-133,000	16,704,469	20 Nov 2025	By Blue Media, LLC
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.37%	$2,293,217	$68.97	-33,250	9,041,283	20 Nov 2025	By Gray Media, LLC
Andrew Polovin	TEM	Class A Common Stock	Sale	-5.04%	$434,707	$68.06	-6,387	120,464	19 Nov 2025	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-0.83%	$1,102,944	$65.54	-16,829	2,003,213	18 Nov 2025	Direct
James William Rogers	TEM	Class A Common Stock	Sale	-5.24%	$475,611	$65.54	-7,257	131,216	18 Nov 2025	Direct
Andrew Polovin	TEM	Class A Common Stock	Sale	-3.94%	$341,126	$65.54	-5,205	126,851	18 Nov 2025	Direct
Erik Phelps	TEM	Class A Common Stock	Sale	-3.75%	$231,547	$65.54	-3,533	90,582	18 Nov 2025	Direct
Ryan Fukushima	TEM	Class A Common Stock	Sale	-1.2%	$661,870	$65.54	-10,099	829,081	18 Nov 2025	Direct
Ryan M. Bartolucci	TEM	Class A Common Stock	Sale	-4%	$120,197	$65.54	-1,834	44,061	18 Nov 2025	Direct
Jennifer A. Doudna	TEM	Class A Comnmon Stock	Sale	-7.25%	$137,613	$71.45	-1,926	24,628	11 Nov 2025	Direct
Ryan Fukushima	TEM	Class A Common Stock	Sale	-3.85%	$445,160	$89.03	-5,000	125,000	03 Nov 2025	By Spouse
David R. Epstein	TEM	Class A Common Stock	Sale	-1.37%	$33,300	$90.00	-370	26,671	03 Nov 2025	Direct
Eric P. Lefkofsky	TEM	Class A Common Stock	Sale	-1.51%	$23,703,188	$89.11	-266,000	17,337,470	28 Oct 2025	By Blue Media, LLC

* An asterisk sign (*) next to the price indicates that the price is likely invalid.