Insider Trading & Ownership of David R. Epstein

Location: New York, NY
Summary: The estimated net worth of David R. Epstein is at least $2.15M dollars as of December 3, 2025. David R. Epstein is the Director of Tempus AI, Inc. and owns shares of Tempus AI, Inc. (TEM) stock worth about $2M. David R. Epstein is the Director of Axcella Health Inc. and owns shares of Axcella Health Inc. stock worth about $122K. David R. Epstein is the Director of Evelo Biosciences, Inc. and owns shares of Evelo Biosciences, Inc. stock worth about $31K.
Signature: /s/ Andrew Polovin, Attorney-in-Fact
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Ownership of David R. Epstein

Symbol	Company	Relationship	Holdings Value	Past Year Net Change	Change %	Report Period
TEM	Tempus AI, Inc.	Director	$2M	-$205K	-9.32%	Dec 1, 2025
AXLA	Axcella Health Inc.	Director	$122K			May 19, 2022
EVLO	Evelo Biosciences, Inc.	Director	$31K			Jun 30, 2022
OHAA	Opy Acquisition Corp. I	Director				Oct 26, 2021
RUBY	Rubius Therapeutics, Inc.	Director				May 12, 2022
SGEN	Seagen Inc.	CEO, Director				Dec 14, 2023
SNTI	Senti Biosciences, Inc.	Director				Jul 13, 2022

Sym	Company	Class	Transaction	%	Value $	* Price $	Shares	Shares After	Date	Ownership

* An asterisk sign (*) next to the price indicates that the price is likely invalid.