Comparable stake leader
ARK Investment Management LLC
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001674416.
Comparable stake leader
ARK Investment Management LLC
Disclosed value leader
ARK Investment Management LLC
Comparable rows
5/50
Latest evidence
26 Oct 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
5 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| ARK Investment Management LLC |
13D/G
13F
Company
|
12%
Reported 13D/G
· 31 Mar 2026
|
$538,189,046
11,313,623 shares
|
+$72,622,740 | 31 Mar 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
8.3%
Reported 13D/G
· 30 Jun 2026
|
$455,353,197
8,348,977 shares
|
— | 30 Jun 2026 |
| ORBIS INVESTMENT MANAGEMENT LTD |
13D/G
|
5.6%
Reported 13D/G
· 30 Jun 2026
|
$289,868,902
5,433,344 shares
|
-$35,042,948 | 30 Jun 2026 |
| Capital World Investors |
13D/G
13F
Company
|
5.1%
Reported 13D/G
· 31 Mar 2026
|
$270,280,537
4,929,428 shares
|
$0 | 31 Mar 2026 |
| Capital International Investors |
13F
13D/G
Company
|
1.2%
Reported 13D/G
· 30 Jan 2026
|
$69,178,918
1,268,407 shares
|
— | 30 Jun 2026 |
| Orbis Allan Gray Ltd |
13F
Company
|
—
denominator unverified
|
$297,197,241
5,449,161 shares
|
— | 30 Jun 2026 |
| STATE STREET CORP |
13F
Company
|
—
denominator unverified
|
$235,703,664
4,321,666 shares
|
— | 30 Jun 2026 |
| GSK plc |
13F
Company
|
—
denominator unverified
|
$175,652,997
3,220,627 shares
|
— | 30 Jun 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$17,937,533.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 93,558 | $0 | $4,881,673 | -$4,881,673 |
| 3-6 | 0 | 3,786 | $0 | $210,577 | -$210,577 |
| 6-9 | 0 | 65,405 | $0 | $3,227,835 | -$3,227,835 |
| 9-12 | 0 | 164,672 | $0 | $9,617,447 | -$9,617,447 |
Reporting owners
Showing 1-20 of 24 reporting-owner rows connected to CRISPR Therapeutics AG. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Simeon George | Director | $96,482,118 | -$720,373 | -0.74% | Mixed | 14 Oct 2026 |
| Rodger Novak | President, Director | $35,814,599 | Mixed | 30 Jun 2021 | ||
| Samarth Kulkarni | Chief Executive Officer, Director | $15,526,332 | -$9,601,329 | -38% | Filing P/S | 26 Oct 2026 |
| James R. Kasinger | General Counsel and Secretary | $4,721,915 | -$1,371,411 | -23% | Filing P/S | 26 Oct 2026 |
| Tony W. Ho | Executive VP, Head of R&D | $3,272,902 | Mixed | 03 Dec 2021 | ||
| Douglas A. Treco | Director | $1,254,660 | Filing P/S | 05 Jun 2026 | ||
| Naimish Patel | Chief Medical Officer | $1,076,636 | -$362,596 | -25% | Filing P/S | 26 Oct 2026 |
| Ali Behbahani | Director | $951,388 | -$780,935 | -45% | Mixed | 17 Sep 2026 |
| Raju Prasad | Chief Financial Officer | $808,010 | -$5,100,887 | -86% | Mixed | 07 Aug 2026 |
| Julianne Bruno | Chief Operating Officer | $726,967 | Mixed | 20 Mar 2025 | ||
| Brendan Smith | Chief Financial Officer | $317,015 | Mixed | 18 Feb 2023 | ||
| John Greene | Director | $313,948 | Filing P/S | 05 Jun 2026 | ||
| Phuong Khanh Morrow | Chief Medical Officer | $275,700 | Mixed | 13 Oct 2023 | ||
| Briggs Morrison | Director | $195,806 | Mixed | 05 Jun 2026 | ||
| Michael John Tomsicek | Chief Financial Officer | $118,193 | Mixed | 06 Aug 2021 | ||
| Sivakesava Sakhamuri | Chief Technical Officer | Mixed | 04 Nov 2026 | |||
| Lawrence Otto Klein | Cbo & Coo | Mixed | 16 Aug 2022 | |||
| Christian Rommel | Director | Mixed | 05 Jun 2026 | |||
| Sandesh Mahatme | Director | Mixed | 05 Jun 2026 | |||
| Bradley J. Bolzon PhD | Director | Mixed | 09 Jun 2022 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Sivakesava Sakhamuri | CRSP | Restricted Stock Units | Award | 40,000 | 40,000 | 04 Nov 2026 | Direct | |||
| Sivakesava Sakhamuri | CRSP | Stock Option (Right to Buy) | Award | 90,000 | 90,000 | 04 Nov 2026 | Direct | |||
| Andrew Jacob Silver | CRSP | Restricted Stock Units | Award | 9,000 | 9,000 | 26 Oct 2026 | Direct | |||
| Andrew Jacob Silver | CRSP | Stock Option (Right to Buy) | Award | 18,000 | 18,000 | 26 Oct 2026 | Direct | |||
| James R. Kasinger | CRSP | Restricted Stock Units | Award | 9,000 | 9,000 | 26 Oct 2026 | Direct | |||
| James R. Kasinger | CRSP | Stock Option (Right to Buy) | Award | 18,000 | 18,000 | 26 Oct 2026 | Direct | |||
| Samarth Kulkarni | CRSP | Restricted Stock Units | Award | 28,750 | 28,750 | 26 Oct 2026 | Direct | |||
| Samarth Kulkarni | CRSP | Stock Option (Right to Buy) | Award | 57,500 | 57,500 | 26 Oct 2026 | Direct | |||
| Naimish Patel | CRSP | Restricted Stock Units | Award | 12,000 | 12,000 | 26 Oct 2026 | Direct | |||
| Naimish Patel | CRSP | Stock Option (Right to Buy) | Award | 24,000 | 24,000 | 26 Oct 2026 | Direct | |||
| Andrew Jacob Silver | CRSP | Restricted Stock Units | Award | 25,000 | 25,000 | 19 Oct 2026 | Direct | |||
| Samarth Kulkarni | CRSP | Common Shares | Sale | -13.3% | -$2,381,326 | $49.78 | -47,837 | 311,899 | 19 Oct 2026 | Direct |
| Samarth Kulkarni | CRSP | Common Shares | Options Exercise | 38.5% | 100,000 | 359,736 | 16 Oct 2026 | Direct | ||
| Samarth Kulkarni | CRSP | Restricted Stock Units | Options Exercise | -33.3% | -100,000 | 200,000 | 16 Oct 2026 | Direct | ||
| Simeon George | CRSP | Common Shares | Sale | -48.4% | -$720,373 | $49.63 | -14,514 | 15,486 | 14 Oct 2026 | Direct |
| Simeon George | CRSP | Common Shares | Options Exercise | 30,000 | 30,000 | 14 Oct 2026 | Direct | |||
| Simeon George | CRSP | Stock Option (Right to Buy) | Options Exercise | -100% | -30,000 | 0 | 14 Oct 2026 | Direct | ||
| James R. Kasinger | CRSP | Common Shares | Sale | -1.07% | -$51,230 | $49.26 | -1,040 | 95,857 | 14 Oct 2026 | Direct |
| Samarth Kulkarni | CRSP | Common Shares | Sale | -1.55% | -$201,867 | $49.26 | -4,098 | 259,736 | 14 Oct 2026 | Direct |
| James R. Kasinger | CRSP | Common Shares | Options Exercise | 2.23% | 2,113 | 96,897 | 13 Oct 2026 | Direct | ||
| James R. Kasinger | CRSP | Restricted Stock Units | Options Exercise | -100% | -2,113 | 0 | 13 Oct 2026 | Direct | ||
| Samarth Kulkarni | CRSP | Common Shares | Options Exercise | 3.26% | 8,333 | 263,834 | 13 Oct 2026 | Direct | ||
| Samarth Kulkarni | CRSP | Restricted Stock Units | Options Exercise | -100% | -8,333 | 0 | 13 Oct 2026 | Direct | ||
| James R. Kasinger | CRSP | Common Shares | Sale | -2.06% | -$119,481 | $60.04 | -1,990 | 94,784 | 06 Oct 2026 | Direct |
| James R. Kasinger | CRSP | Common Shares | Options Exercise | 2.1% | 1,990 | 96,774 | 06 Oct 2026 | Direct | ||
| James R. Kasinger | CRSP | Stock Option (Right to Buy) | Options Exercise | -2.39% | -1,990 | 81,242 | 06 Oct 2026 | Direct | ||
| James R. Kasinger | CRSP | Common Shares | Sale | -9.89% | -$626,460 | $60.24 | -10,400 | 94,784 | 22 Sep 2026 | Direct |
| James R. Kasinger | CRSP | Common Shares | Options Exercise | 11% | 10,400 | 105,184 | 22 Sep 2026 | Direct | ||
| James R. Kasinger | CRSP | Stock Option (Right to Buy) | Options Exercise | -11.1% | -10,400 | 83,232 | 22 Sep 2026 | Direct | ||
| Ali Behbahani | CRSP | Common Shares | Sale | -45.1% | -$780,935 | $57.09 | -13,679 | 16,637 | 17 Sep 2026 | Direct |
| Ali Behbahani | CRSP | Common Shares | Options Exercise | 9493.7% | 30,000 | 30,316 | 17 Sep 2026 | Direct | ||
| Ali Behbahani | CRSP | Stock Option (Right to Buy) | Options Exercise | -100% | -30,000 | 0 | 17 Sep 2026 | Direct | ||
| Raju Prasad | CRSP | Common Shares | Gift | -4.82% | -750 | 14,815 | 07 Aug 2026 | Direct | ||
| Simeon George | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Ali Behbahani | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Maria Fardis | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Harold Edward Fleming | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| John Greene | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Katherine A. High | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Sandesh Mahatme | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Briggs Morrison | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Christian Rommel | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| Douglas A. Treco | CRSP | Stock Option (Right to Buy) | Award | 13,000 | 13,000 | 05 Jun 2026 | Direct | |||
| James R. Kasinger | CRSP | Restricted Stock Units | Award | 17,000 | 17,000 | 29 May 2026 | Direct | |||
| Naimish Patel | CRSP | Restricted Stock Units | Award | 22,000 | 22,000 | 29 May 2026 | Direct | |||
| Raju Prasad | CRSP | Restricted Stock Units | Award | 19,500 | 19,500 | 29 May 2026 | Direct | |||
| Naimish Patel | CRSP | Common Shares | Sale | -16.4% | -$210,577 | $55.62 | -3,786 | 19,357 | 29 May 2026 | Direct |
| Naimish Patel | CRSP | Common Shares | Options Exercise | 76.1% | 10,000 | 23,143 | 28 May 2026 | Direct | ||
| Naimish Patel | CRSP | Restricted Stock Units | Options Exercise | -33.3% | -10,000 | 20,000 | 28 May 2026 | Direct | ||
| James R. Kasinger | CRSP | Common Shares | Sale | -3.26% | -$148,854 | $46.78 | -3,182 | 94,308 | 23 Mar 2026 | Direct |