| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 11% | -9.1% | $634,293,720 | -$24,525,854 | 9,786,973 | -3.7% | ARK Investment Management LLC | 30 Sep 2025 |
| Capital International Investors | 7.4% | $236,896,911 | 6,334,142 | Capital International Investors | 31 Mar 2025 | |||
| BlackRock, Inc. | 6.9% | $288,553,541 | 5,932,433 | BlackRock, Inc. | 30 Jun 2025 | |||
| ORBIS INVESTMENT MANAGEMENT LTD | 5.5% | $322,373,041 | 4,974,125 | ORBIS INVESTMENT MANAGEMENT LTD | 30 Sep 2025 |
As of 30 Sep 2025, 431 institutional investors reported holding 72,231,465 shares of CRISPR Therapeutics AG - Common Stock (CRSP). This represents 80% of the company’s total 90,438,636 outstanding shares.
The largest institutional shareholders of CRISPR Therapeutics AG - Common Stock (CRSP) together control 68% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| ARK Investment Management LLC | 11% | 9,786,973 | -3.9% | 3.8% | $634,293,721 |
| BlackRock, Inc. | 7.8% | 7,050,145 | +16% | 0.01% | $456,919,897 |
| Capital International Investors | 6.2% | 5,649,258 | +0.99% | 0.06% | $366,128,411 |
| Orbis Allan Gray Ltd | 5.5% | 4,982,085 | +80% | 1.4% | $322,888,929 |
| STATE STREET CORP | 4.4% | 4,007,233 | +23% | 0.01% | $259,708,771 |
| T. Rowe Price Investment Management, Inc. | 3.6% | 3,282,584 | -11% | 0.13% | $212,745,000 |
| VANGUARD GROUP INC | 2.6% | 2,364,645 | +2.9% | 0% | $153,252,642 |
| UBS Group AG | 2.6% | 2,339,056 | -18% | 0.03% | $151,594,219 |
| Sumitomo Mitsui Trust Group, Inc. | 2.4% | 2,163,675 | -10% | 0.08% | $140,227,777 |
| Amova Asset Management Americas, Inc. | 2.4% | 2,163,675 | -10% | 1.4% | $140,184,503 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 2,141,170 | +3.3% | 0.01% | $138,790,458 |
| SR One Capital Management, LP | 2.3% | 2,038,763 | +94% | 19% | $132,132,230 |
| FMR LLC | 2.1% | 1,885,663 | -2.3% | 0.01% | $122,209,804 |
| MORGAN STANLEY | 1.5% | 1,397,859 | +173% | 0.01% | $90,595,300 |
| EcoR1 Capital, LLC | 1.5% | 1,389,276 | 0% | 4.3% | $90,038,978 |
| BANK OF AMERICA CORP /DE/ | 1.2% | 1,124,119 | -22% | 0.01% | $72,854,128 |
| NEA Management Company, LLC | 1.2% | 1,058,570 | -33% | 3.8% | $68,605,922 |
| TWO SIGMA INVESTMENTS, LP | 1.2% | 1,044,689 | -32% | 0.1% | $67,706,294 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.1% | 985,770 | +5.6% | 0.01% | $63,887,754 |
| LOOMIS SAYLES & CO L P | 1% | 909,714 | +6.2% | 0.07% | $58,958,564 |
| DIMENSIONAL FUND ADVISORS LP | 0.97% | 877,029 | -4.4% | 0.01% | $56,833,530 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.9% | 814,324 | +5.8% | 0.08% | $52,776,339 |
| NORTHERN TRUST CORP | 0.86% | 779,930 | +2.5% | 0.01% | $50,547,263 |
| JPMORGAN CHASE & CO | 0.66% | 593,416 | +85% | 0% | $38,459,291 |
| TWO SIGMA ADVISERS, LP | 0.63% | 572,972 | -57% | 0.07% | $37,134,315 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 390,619 | $21,067,441 | -$8,365,075 | $52.44 | 28 |
| 2025 Q3 | 72,231,465 | $4,680,402,820 | +$28,372,253 | $64.81 | 431 |
| 2025 Q2 | 72,314,703 | $3,517,677,257 | +$428,897,837 | $48.64 | 426 |
| 2025 Q1 | 64,129,300 | $2,183,568,653 | -$16,834,672 | $34.03 | 388 |
| 2024 Q4 | 64,443,699 | $2,536,549,693 | +$179,624,639 | $39.36 | 398 |
| 2024 Q3 | 59,826,628 | $2,811,325,020 | +$6,501,203 | $46.98 | 407 |
| 2024 Q2 | 59,510,276 | $3,214,159,736 | +$50,043,500 | $54.01 | 439 |
| 2024 Q1 | 57,288,998 | $3,904,937,558 | +$217,314,654 | $68.16 | 469 |
| 2023 Q4 | 55,520,285 | $3,475,779,179 | +$42,550,297 | $62.60 | 465 |
| 2023 Q3 | 54,993,134 | $2,496,662,136 | -$1,898,845 | $45.39 | 400 |
| 2023 Q2 | 54,718,539 | $3,071,120,295 | -$80,853,798 | $56.14 | 409 |
| 2023 Q1 | 56,199,828 | $2,540,792,585 | +$38,754,979 | $45.23 | 375 |
| 2022 Q4 | 55,494,852 | $2,255,613,450 | -$74,822,214 | $40.65 | 386 |
| 2022 Q3 | 56,683,321 | $3,701,432,142 | -$78,744,860 | $65.35 | 410 |
| 2022 Q2 | 55,502,675 | $3,344,489,851 | +$271,662,077 | $60.77 | 404 |
| 2022 Q1 | 49,481,600 | $3,107,777,604 | +$483,746,495 | $62.77 | 415 |
| 2021 Q4 | 42,884,873 | $3,253,105,466 | +$73,035,179 | $75.78 | 425 |
| 2021 Q3 | 40,405,115 | $4,522,264,525 | -$41,114,506 | $111.93 | 458 |
| 2021 Q2 | 40,533,549 | $6,560,272,742 | -$153,120,996 | $161.89 | 484 |
| 2021 Q1 | 42,643,720 | $5,195,793,257 | -$576,803,869 | $121.85 | 431 |
| 2020 Q4 | 47,170,730 | $7,222,892,447 | +$35,286,644 | $153.11 | 397 |
| 2020 Q3 | 47,858,309 | $4,002,814,216 | +$723,322,979 | $83.64 | 300 |
| 2020 Q2 | 38,277,395 | $2,809,424,935 | +$279,188,892 | $73.49 | 263 |
| 2020 Q1 | 35,534,767 | $1,506,022,854 | +$153,360,658 | $42.41 | 244 |
| 2019 Q4 | 31,537,408 | $1,920,718,365 | +$255,276,153 | $60.90 | 248 |
| 2019 Q3 | 27,534,073 | $1,131,426,201 | -$8,297,966 | $40.99 | 176 |
| 2019 Q2 | 27,401,117 | $1,290,347,942 | +$107,556,651 | $47.10 | 176 |
| 2019 Q1 | 26,007,044 | $928,966,936 | +$146,098,285 | $35.72 | 163 |
| 2018 Q4 | 22,084,355 | $630,914,836 | -$57,784,767 | $28.57 | 151 |
| 2018 Q3 | 22,857,503 | $1,013,718,783 | +$176,760,080 | $44.35 | 171 |
| 2018 Q2 | 18,496,060 | $1,086,865,478 | -$651,038 | $58.76 | 171 |
| 2018 Q1 | 18,718,531 | $855,401,603 | +$303,959,521 | $45.71 | 132 |
| 2017 Q4 | 12,499,892 | $293,264,477 | +$61,797,532 | $23.48 | 82 |
| 2017 Q3 | 10,055,642 | $179,590,160 | +$6,177,091 | $17.87 | 61 |
| 2017 Q2 | 9,694,198 | $155,107,419 | -$4,334,397 | $16.02 | 36 |
| 2017 Q1 | 9,693,488 | $210,826,092 | -$2,609,245 | $21.77 | 36 |
| 2016 Q4 | 9,833,888 | $197,779,000 | +$197,766,000 | $20.26 | 26 |
| 2016 Q2 | 0 | $0 | -$1,000 | $52.44 | 0 |
| 2016 Q1 | 40 | $1,000 | $25.00 | 1 |