Comparable stake leader
BAKER BROS. ADVISORS LP
SEC ownership of BeOne Medicines Ltd.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001651308.
Disclosed value leader
BAKER BROS. ADVISORS LP
Comparable rows
3/50
Latest evidence
27 Oct 2026
- Public ticker
- ONC on Nasdaq, BEIGF on OTC
- Parsed ownership sources
-
13D/G, 3/4/5, and 13F
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
BAKER BROS. ADVISORS LP
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
3 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
BAKER BROS. ADVISORS LP
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
27 Oct 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001651308
- Issuer location
- Basel
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of BeOne Medicines Ltd. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
BAKER BROS. ADVISORS LP
Disclosed value leader
BAKER BROS. ADVISORS LP
Comparable rows
3/50
Latest evidence
27 Oct 2026
13D/G
3/4/5
13F
Lead comparable stake: 7.8%
47 rows are not safely comparable across share classes.
13D/G row: BAKER BROS. ADVISORS LP
Showing 1-8 of 50 holder rows.
Quick read
BAKER BROS. ADVISORS LP leads the comparable SEC ownership view at 7.8%.
3 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens BAKER BROS. ADVISORS LP's linked filing trail.
Comparable ownership
Top 3
BAKER BROS. ADVISORS LP
7.8%
HHLR ADVISORS, LTD.
4.9%
Capital International Investors
4.2%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP |
13D/G
3/4/5
13F
Julian C. Baker · Director · Company
|
7.8%
Reported 13D/G
· 14 Sep 2026
|
$43,405,871,459
115,912,814 shares
|
$0 | 14 Sep 2026 |
| HHLR ADVISORS, LTD. |
3/4/5
13D/G
10%+ Owner
|
4.9%
Reported 13D/G
· 09 May 2025
|
$25,009,148,200
125,045,741 shares
|
— | 02 Dec 2024 |
| Capital International Investors |
13F
13D/G
Company
|
4.2%
Reported 13D/G
· 31 Mar 2026
|
$1,201,254,811
4,210,221 shares
|
— | 30 Jun 2026 |
| AMGEN INC |
3/4/5
10%+ Owner
|
—
denominator unverified
|
$3,419,356,261
18,943,802 shares
|
— | 10 Sep 2021 |
| Xiaodong Wang |
3/4/5
Director, Chair, Scientific Advisory Brd
|
—
denominator unverified
|
$1,678,992,368
4,588,163 shares
|
-$24,684,650 | 27 Oct 2026 |
| PRIMECAP MANAGEMENT CO/CA/ |
13F
Company
|
—
denominator unverified
|
$1,427,110,097
5,007,931 shares
|
— | 30 Jun 2026 |
| FMR LLC |
13F
Company
|
—
denominator unverified
|
$706,305,845
2,478,527 shares
|
— | 30 Jun 2026 |
| Lai Wang |
3/4/5
President, Global Head of R&D
|
—
mixed-class rows
|
$677,973,303
2,512,744 shares
mixed-class rows
|
-$1,171,353 | 23 Jun 2026 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$368,933,707.
Buys
$0
Insiders: 0
Sells
$368,933,707
Insiders: 11
Net
-$368,933,707
Shares: -1,136,849
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 1,136,849
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 315,475 | $0 | $113,058,192 | -$113,058,192 |
| 3-6 | 0 | 694,090 | $0 | $215,387,867 | -$215,387,867 |
| 6-9 | 0 | 2,333 | $0 | $785,944 | -$785,944 |
| 9-12 | 0 | 124,951 | $0 | $39,701,704 | -$39,701,704 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-20 of 31 reporting-owner rows connected to BeOne Medicines Ltd.. Open a relationship link for the CIK-to-CIK filing trail.
Rows
31
Largest Forms 3/4/5 holder
HHLR ADVISORS, LTD.
Net 12M change
-$368.93M
Full value: -$368,933,707 · USD · 12-month changeLatest report
27 Oct 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| HHLR ADVISORS, LTD. | 10%+ Owner | $25,009,148,200 | Filing P/S | 02 Dec 2024 | ||
| AMGEN INC | 10%+ Owner | $3,419,356,261 | Mixed | 10 Sep 2021 | ||
| BAKER BROS. ADVISORS LP | Director | $2,146,532,727 | Mixed | 14 Sep 2026 | ||
| Xiaodong Wang | Director, Chair, Scientific Advisory Brd | $1,678,992,368 | -$24,684,650 | -1.4% | Median | 27 Oct 2026 |
| Lai Wang | President, Global Head of R&D | $677,973,303 | -$1,171,353 | -0.17% | Mixed | 23 Jun 2026 |
| Donald W. Glazer | Director | $564,671,459 | Mixed | 05 Jun 2024 | ||
| John Oyler | Chief Executive Officer, Director | $408,412,307 | -$327,881,663 | -45% | Mixed | 10 Aug 2026 |
| Xiaobin Wu | President and COO | $363,071,010 | -$8,753,697 | -2.4% | Mixed | 25 Aug 2026 |
| Howard Liang | CFO & Chief Strategy Officer | $322,615,606 | Mixed | 28 Jun 2021 | ||
| Aaron Rosenberg | Chief Financial Officer | $109,100,764 | -$524,448 | -0.48% | Mixed | 03 Aug 2026 |
| Chan Henry Lee | SVP, General Counsel | $88,718,000 | -$4,632,539 | -5% | Mixed | 30 Sep 2026 |
| Julia Aijun Wang | Chief Financial Officer | $88,611,076 | Mixed | 01 Jul 2024 | ||
| Baker Brothers Life Sciences LP | Director | $46,037,187 | Mixed | 14 Sep 2026 | ||
| Felix Baker | Director | $46,037,187 | Mixed | 14 Sep 2026 | ||
| Julian C. Baker | Director | $46,037,187 | Mixed | 14 Sep 2026 | ||
| 667, L.P. | Director | $46,037,187 | Mixed | 14 Sep 2026 | ||
| Baker Bros. Advisors (GP) LLC | Director | $46,037,187 | Mixed | 14 Sep 2026 | ||
| Jane Huang | CMO, Hematology | $33,246,160 | Mixed | 14 Dec 2021 | ||
| Titus B. Ball | Principal Accounting Officer | $27,906,827 | -$127,341 | -0.45% | Mixed | 01 Sep 2026 |
| Anthony C. Hooper | Director | $24,862,328 | Mixed | 11 Jun 2026 |
Recent insider transactions for BeOne Medicines Ltd.
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Xiaodong Wang | ONC | American Depositary Shares | Sale | -100% | -31,028 | 0 | 27 Oct 2026 | Direct | ||
| Xiaodong Wang | ONC | American Depositary Shares | Options Exercise | 31,028 | 31,028 | 27 Oct 2026 | Direct | |||
| Xiaodong Wang | ONC | Share Option (Right to Buy) | Options Exercise | -100% | -403,364 | 0 | 27 Oct 2026 | Direct | ||
| Xiaodong Wang | ONC | American Depositary Shares | Sale | -100% | -31,027 | 0 | 13 Oct 2026 | Direct | ||
| Xiaodong Wang | ONC | American Depositary Shares | Options Exercise | 31,027 | 31,027 | 13 Oct 2026 | Direct | |||
| Xiaodong Wang | ONC | Share Option (Right to Buy) | Options Exercise | -50% | -403,351 | 403,364 | 13 Oct 2026 | Direct | ||
| Chan Henry Lee | ONC | American Depositary Shares | Sale | -100% | -$418,125 | $375.00 | -1,115 | 0 | 30 Sep 2026 | Direct |
| Xiaodong Wang | ONC | American Depositary Shares | Sale | -100% | -$11,318,558 | $364.79 | -31,028 | 0 | 28 Sep 2026 | Direct |
| Xiaodong Wang | ONC | American Depositary Shares | Options Exercise | 31,028 | 31,028 | 28 Sep 2026 | Direct | |||
| Xiaodong Wang | ONC | Share Option (Right to Buy) | Options Exercise | -33.3% | -403,364 | 806,715 | 28 Sep 2026 | Direct | ||
| BAKER BROS. ADVISORS LP | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| BAKER BROS. ADVISORS LP | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| BAKER BROS. ADVISORS LP | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | American Depositary Shares | Options Exercise | 0.77% | 61,536 | 8,099,179 | 14 Sep 2026 | See Footnotes | ||
| BAKER BROS. ADVISORS LP | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| BAKER BROS. ADVISORS LP | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| BAKER BROS. ADVISORS LP | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| Baker Bros. Advisors Lp | ONC | Non-Qualified Share Options | Options Exercise | -100% | -61,536 | 0 | 14 Sep 2026 | See Footnotes | ||
| Xiaodong Wang | ONC | American Depositary Shares | Options Exercise | 31,027 | 31,027 | 08 Sep 2026 | Direct | |||
| Xiaodong Wang | ONC | American Depositary Shares | Sale | -100% | -$13,366,092 | $349.10 | -38,287 | 0 | 08 Sep 2026 | Direct |
| Xiaodong Wang | ONC | Share Option (Right to Buy) | Options Exercise | -25% | -403,351 | 1,210,079 | 08 Sep 2026 | Direct | ||
| Titus B. Ball | ONC | American Depositary Shares | Sale | -100% | -$46,974 | $355.86 | -132 | 0 | 01 Sep 2026 | Direct |
| Xiaobin Wu | ONC | American Depositary Shares | Sale | -100% | -$106,400 | $380.00 | -280 | 0 | 25 Aug 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$19,659,594 | $358.15 | -54,892 | 0 | 12 Aug 2026 | Direct |
| Chan Henry Lee | ONC | American Depositary Shares | Sale | -100% | -$959,760 | $360.00 | -2,666 | 0 | 11 Aug 2026 | Direct |
| Chan Henry Lee | ONC | American Depositary Shares | Options Exercise | 2,666 | 2,666 | 11 Aug 2026 | Direct | |||
| Chan Henry Lee | ONC | Share Option (Right to Buy) | Options Exercise | -100% | -34,658 | 0 | 11 Aug 2026 | Direct | ||
| John Oyler | ONC | American Depositary Shares | Sale | -56.4% | -$25,661,417 | $361.90 | -70,907 | 54,892 | 11 Aug 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Sale | -47.8% | -$41,159,461 | $357.87 | -115,011 | 125,799 | 10 Aug 2026 | Direct |
| Aaron Rosenberg | ONC | American Depositary Shares | Sale | -100% | -$361,811 | $312.72 | -1,157 | 0 | 03 Aug 2026 | Direct |
| Chan Henry Lee | ONC | American Depositary Shares | Sale | -100% | -$337,932 | $323.69 | -1,044 | 0 | 30 Jul 2026 | Direct |
| Chan Henry Lee | ONC | American Depositary Shares | Sale | -100% | -$542,425 | $325.00 | -1,669 | 0 | 22 Jul 2026 | Direct |
| Chan Henry Lee | ONC | American Depositary Shares | Options Exercise | 1,669 | 1,669 | 22 Jul 2026 | Direct | |||
| Chan Henry Lee | ONC | Share Option (Right to Buy) | Options Exercise | -67.3% | -21,697 | 10,556 | 22 Jul 2026 | Direct | ||
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$19,504,058 | $317.67 | -61,397 | 0 | 21 Jul 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Options Exercise | 33,990 | 33,990 | 20 Jul 2026 | Direct | |||
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$15,086,797 | $312.25 | -48,316 | 0 | 20 Jul 2026 | Direct |
| John Oyler | ONC | Share Option (Right to Buy) | Options Exercise | -100% | -441,870 | 0 | 20 Jul 2026 | Direct | ||
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$20,163,907 | $312.00 | -64,628 | 0 | 17 Jul 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Options Exercise | 64,628 | 64,628 | 17 Jul 2026 | Direct | |||
| John Oyler | ONC | Share Option (Right to Buy) | Options Exercise | -65.5% | -840,164 | 441,870 | 17 Jul 2026 | Direct | ||
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$52,992,224 | $318.09 | -166,597 | 0 | 16 Jul 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Options Exercise | 166,597 | 166,597 | 16 Jul 2026 | Direct | |||
| John Oyler | ONC | Share Option (Right to Buy) | Options Exercise | -100% | -2,165,761 | 0 | 16 Jul 2026 | Direct | ||
| John Oyler | ONC | American Depositary Shares | Sale | -100% | -$36,359,374 | $311.94 | -116,557 | 0 | 15 Jul 2026 | Direct |
| John Oyler | ONC | American Depositary Shares | Options Exercise | 116,557 | 116,557 | 15 Jul 2026 | Direct |
* marks a reported price that did not pass the local price check.