SEC ownership of Summit Therapeutics Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001599298.

Comparable stake leader

Robert W. Duggan

Disclosed value leader

Robert W. Duggan

Comparable rows

0/50

Latest evidence

12 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 1 signal
Latest parsed ownership date
12 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001599298
Issuer location
Miami, FL

Ownership snapshot

Top shareholders of Summit Therapeutics Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
Robert W. Duggan
Disclosed value leader
Robert W. Duggan
Comparable rows
0/50
Latest evidence
12 Jun 2026
3/4/5 13F Highest disclosed value: $8,324,567,933 50 rows are not safely comparable across share classes. Showing 1-8 of 50 holder rows.

Quick read

Robert W. Duggan has the largest disclosed position value at $8.32B.

0 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens Robert W. Duggan's linked filing trail.
Disclosed position value Top 5
Robert W. Duggan $8.32B
Mahkam Zanganeh $8.21B
BAKER BROS. ADVISORS LP $689.97M
Yu Xia $600.8M
FMR LLC $205.78M

Value bars compare disclosed positions; verify each figure against the linked filing evidence.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
Robert W. Duggan
3/4/5
Co-Chief Executive Officer, Director, 10%+ Owner
mixed-class rows
$8,324,567,933
622,015,239 shares
mixed-class rows
+$57,931,939 12 Jun 2026
Mahkam Zanganeh
3/4/5
Co-Chief Executive Officer, Director, 10%+ Owner
mixed-class rows
$8,214,516,275
619,617,599 shares
mixed-class rows
+$57,931,939 12 Jun 2026
BAKER BROS. ADVISORS LP
13F
Company
13F
class O/S missing
$689,974,554
36,391,063 shares
31 Mar 2026
Yu Xia
3/4/5
Director
mixed-class rows
$600,800,855
32,092,147 shares
mixed-class rows
+$9,999,983 02 Jan 2026
FMR LLC
13F
Company
13F
class O/S missing
$205,776,661
10,853,199 shares
31 Mar 2026
BlackRock, Inc.
13F
Company
13F
class O/S missing
$183,035,250
9,653,758 shares
31 Mar 2026
PRICE T ROWE ASSOCIATES INC /MD/
13F
Company
13F
class O/S missing
$156,949,000
8,277,859 shares
31 Mar 2026
STATE STREET CORP
13F
Company
13F
class O/S missing
$133,253,914
7,028,160 shares
31 Mar 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to buying over the last 12 months. Net value: +$126,586,111.

Buys
$126,586,111
Insiders: 4
Sells
$0
Insiders: 0
Net
+$126,586,111
Shares: +9,133,765
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 9,133,765 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 7,870,000 0 $103,616,650 $0 +$103,616,650
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 1,263,765 0 $22,969,461 $0 +$22,969,461

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-14 of 14 reporting-owner rows connected to Summit Therapeutics Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
14
Largest Forms 3/4/5 holder
Robert W. Duggan
Net 12M change
+$126,586,111
Latest report
12 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Robert W. Duggan Co-Chief Executive Officer, Director, 10%+ Owner $8,324,567,933 +$57,931,939 +0.7% Mixed 12 Jun 2026
Mahkam Zanganeh Co-Chief Executive Officer, Director, 10%+ Owner $8,214,516,275 +$57,931,939 +0.71% Mixed 12 Jun 2026
Yu Xia Director $600,800,855 +$9,999,983 +1.7% Mixed 02 Jan 2026
Manmeet Singh Soni COO and CFO, Director $46,525,591 +$722,250 +1.6% Mixed 04 Jun 2026
Bhaskar Anand Chief Accounting Officer $3,682,233 Mixed 08 Jan 2026
Ankur Dhingra Chief Financial Officer $1,331,093 Filing P/S 26 Mar 2024
Urte Gayko Director $528,000 Mixed 25 Apr 2022
Mostafa Ronaghi Director $321,300 Mixed 02 Jan 2026
Kenneth A. Clark Director $155,892 Mixed 02 Jan 2026
Ujwala Mahatme Director $115,599 Mixed 02 Jan 2024
Jeff Huber Director $86,592 Mixed 02 Jan 2026
Robert F. Booth Director $62,896 Mixed 02 Jan 2026
Alessandra Cesano Director $28,198 Mixed 02 Jan 2026
Jeffrey R. Maranian VP Corporate Controller $19,800 Mixed 15 Dec 2021

Recent insider transactions for Summit Therapeutics Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Mahkam Zanganeh SMMT Common Stock Purchase 0.67% $49,987,200 $13.12 3,810,000 573,883,879 12 Jun 2026 By Spouse
Robert W. Duggan SMMT Common Stock Purchase 0.67% $49,987,200 $13.12 3,810,000 573,883,879 12 Jun 2026 Direct
Robert W. Duggan SMMT Common Stock Purchase 0.39% $1,460,000 $14.60 100,000 25,824,474 04 Jun 2026 By the Mahkam Zanganeh Revocable Trust, with the Spouse of Reporting Person as Trustee
Mahkam Zanganeh SMMT Common Stock Purchase 0.39% $1,460,000 $14.60 100,000 25,824,474 04 Jun 2026 By the Mahkam Zanganeh Revocable Trust, with the Reporting Person as Trustee
Manmeet Singh Soni SMMT Common Stock Purchase 1.63% $722,250 $14.44 50,000 3,123,603 04 Jun 2026 Direct
Bhaskar Anand SMMT Stock Option (right to buy) Award 30,000 30,000 08 Jan 2026 Direct
Mahkam Zanganeh SMMT Stock Option (right to buy) Award 11,232 11,232 02 Jan 2026 By Spouse
Robert W. Duggan SMMT Stock Option (right to buy) Award 11,232 11,232 02 Jan 2026 Direct
Robert F. Booth SMMT Stock Option (right to buy) Award 42,180 35,000 02 Jan 2026 Direct
Yu Xia SMMT Stock Option (right to buy) Award 35,000 35,000 02 Jan 2026 Direct
Jeff Huber SMMT Stock Option (right to buy) Award 44,885 35,000 02 Jan 2026 Direct
Mostafa Ronaghi SMMT Stock Option (right to buy) Award 35,000 35,000 02 Jan 2026 Direct
Kenneth A. Clark SMMT Stock Option (right to buy) Award 52,796 35,000 02 Jan 2026 Direct
Alessandra Cesano SMMT Stock Option (right to buy) Award 38,219 35,000 02 Jan 2026 Direct
Yu Xia SMMT Common Stock Purchase 1.69% $9,999,983 $18.74 533,617 32,057,147 21 Oct 2025 Akeso, Inc.
Bhaskar Anand SMMT Common Stock Award 20% 26,680 159,751 21 Oct 2025 Direct
Manmeet Singh Soni SMMT Common Stock Award 1.77% 53,361 3,073,603 21 Oct 2025 Direct
Robert W. Duggan SMMT Common Stock Purchase 53.4% $499,983 $18.74 26,680 76,680 21 Oct 2025 Immediate family member of Spouse
Robert W. Duggan SMMT Common Stock Award 1.05% 266,808 25,724,474 21 Oct 2025 By the Mahkam Zanganeh Revocable Trust, with the Spouse of Reporting Person as Trustee
Robert W. Duggan SMMT Common Stock Award 2.51% 13,980,789 570,073,879 21 Oct 2025 Direct
Mahkam Zanganeh SMMT Common Stock Award 2.51% 13,980,789 570,073,879 21 Oct 2025 By Spouse
Mahkam Zanganeh SMMT Common Stock Purchase 53.4% $499,983 $18.74 26,680 76,680 21 Oct 2025 Immediate family member
Mahkam Zanganeh SMMT Common Stock Award 1.05% 266,808 25,724,474 21 Oct 2025 By the Mahkam Zanganeh Revocable Trust, with the Reporting Person as Trustee
Bhaskar Anand SMMT Stock Option (right to buy) Award 50,000 50,000 18 Sep 2025 Direct
Mahkam Zanganeh SMMT Common Stock Purchase $90,350 $18.07 5,000 556,093,090 11 Sep 2025 By Spouse
Robert W. Duggan SMMT Common Stock Purchase $90,350 $18.07 5,000 556,093,090 11 Sep 2025 Direct
Mahkam Zanganeh SMMT Common Stock Purchase 0.06% $5,894,406 $17.68 333,394 556,088,090 10 Sep 2025 By Spouse
Robert W. Duggan SMMT Common Stock Purchase 0.06% $5,894,406 $17.68 333,394 556,088,090 10 Sep 2025 Direct
* marks a reported price that did not pass the local price check.
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