Comparable stake leader
ARK Investment Management LLC
SEC ownership of Twist Bioscience Corp
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001581280.
Disclosed value leader
Artisan Partners Limited Partnership
Comparable rows
50/50
Latest evidence
29 May 2026
- Public ticker
- TWST on Nasdaq
- Parsed ownership sources
- 13F, 13D/G, and 3/4/5
- Largest SEC-reported holder
- ARK Investment Management LLC
- Latest 13D/G holder
- ARK Investment Management LLC
- Latest parsed ownership date
- 29 May 2026
- Issuer CIK
- 0001581280
- Issuer location
- South San Francisco, CA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
2 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Twist Bioscience Corp (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
ARK Investment Management...
Disclosed value leader
Artisan Partners Limited ...
Comparable rows
50/50
Latest evidence
29 May 2026
13F
13D/G
3/4/5
Lead comparable stake: 10%
13D/G row: ARK Investment Management LLC
Showing 1-8 of 50 holder rows.
Quick read
ARK Investment Management LLC leads the comparable SEC ownership view at 10%.
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens ARK Investment Management LLC's linked filing trail.
Comparable ownership
Top 5
ARK Investment Management LLC
10%
Artisan Partners Limited Partnership
10%
EdgePoint Investment Group Inc.
8.8%
WILLIAM BLAIR INVESTMENT MANAGEME...
8.6%
BlackRock, Inc.
8.3%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| ARK Investment Management LLC |
13F
13D/G
Company
|
10%
from 13D/G
|
$301,406,681
6,342,733 shares
|
— | 31 Mar 2026 |
| Artisan Partners Limited Partnership |
13F
13D/G
Company · Artisan Partners Asset Management Inc.
|
10%
from 13D/G
|
$302,596,753
6,367,777 shares
|
— | 31 Mar 2026 |
| EdgePoint Investment Group Inc. |
13F
13D/G
Company
|
8.8%
from 13D/G
|
$255,777,398
5,382,521 shares
|
— | 31 Mar 2026 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
13D/G
13F
Company
|
8.6%
|
$264,592,541
5,269,718 shares
|
-$34,379,339 | 31 Mar 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
8.3%
from 13D/G
|
$263,943,282
5,554,362 shares
|
— | 31 Mar 2026 |
| STATE STREET CORP |
13F
13D/G
Company · STATE STREET CORPORATION
|
5.1%
from 13D/G
|
$174,430,809
3,670,682 shares
|
— | 31 Mar 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13D/G
13F
Vanguard Capital Management · Company
|
5%
|
$147,402,716
3,101,909 shares
|
$0 | 31 Mar 2026 |
| Invesco Ltd. |
13F
13D/G
Company
|
3.9%
from 13D/G
|
$103,208,593
2,171,898 shares
|
— | 31 Mar 2026 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$26,943,881.
Buys
$0
Insiders: 0
Sells
$26,943,881
Insiders: 9
Net
-$26,943,881
Shares: -589,461
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 589,461
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 168,226 | $0 | $10,307,696 | -$10,307,696 |
| 3-6 | 0 | 206,163 | $0 | $9,957,630 | -$9,957,630 |
| 6-9 | 0 | 184,935 | $0 | $5,764,285 | -$5,764,285 |
| 9-12 | 0 | 30,137 | $0 | $914,270 | -$914,270 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-19 of 19 reporting-owner rows connected to Twist Bioscience Corp. Open a relationship link for the CIK-to-CIK filing trail.
Rows
19
Largest Forms 3/4/5 holder
Emily M. Leproust
Net 12M change
-$26,832,597
Latest report
29 May 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Emily M. Leproust | Chief Executive Officer, Director | $58,107,360 | -$9,159,225 | -14% | Filing P/S | 28 May 2026 |
| Patrick John Finn | President and COO | $14,635,236 | -$7,470,066 | -34% | Filing P/S | 21 May 2026 |
| William Banyai | Senior Vice President of Advanced Development and General Manager of Data Storage | $12,818,211 | Filing P/S | 03 May 2024 | ||
| Dennis Cho | Senior Vice President, Chief Legal Officer & Corporate Secretary | $8,376,556 | -$2,043,549 | -20% | Filing P/S | 29 May 2026 |
| Adam Laponis | Chief Financial Officer | $7,887,250 | -$2,265,677 | -22% | Filing P/S | 29 May 2026 |
| Paula Green | SVP of Human Resources | $6,475,465 | -$3,105,420 | -32% | Filing P/S | 21 May 2026 |
| Keith Crandell | Director | $3,558,241 | Mixed | 05 Feb 2026 | ||
| Robert Chess | Director | $3,099,486 | -$575,402 | -16% | Mixed | 17 Mar 2026 |
| Robert F. Werner | Chief Accounting Officer | $3,010,854 | -$977,508 | -25% | Filing P/S | 26 May 2026 |
| James M. Thorburn | Chief Financial Officer | $3,000,970 | Mixed | 02 Jan 2024 | ||
| Patrick Weiss | Chief Operating Officer | $1,647,659 | Mixed | 01 Apr 2022 | ||
| Melissa A. Starovasnik | Director | $1,511,096 | -$282,435 | -16% | Filing P/S | 28 May 2026 |
| Nelson Chan | Director | $1,141,839 | Mixed | 05 Feb 2026 | ||
| Xiaoying Mai | Director | $1,086,498 | Mixed | 06 Feb 2024 | ||
| Jan Johannessen | Director | $996,354 | -$953,315 | -49% | Filing P/S | 12 May 2026 |
| Robert P. Ragusa | Director | $995,276 | Mixed | 05 Feb 2026 | ||
| Nicolas Barthelemy | Director | $800,210 | Mixed | 21 Nov 2022 | ||
| Katryn Blake | Director | $667,844 | Mixed | 05 Feb 2026 | ||
| Kevin B. Yankton | Chief Accounting Officer | $316,837 | Mixed | 17 May 2023 |
Recent insider transactions for Twist Bioscience Corp
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Dennis Cho | TWST | Common Stock | Sale | -10.6% | $990,799 | $69.75 | -14,205 | 120,094 | 29 May 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -3.43% | $280,000 | $70.00 | -4,000 | 112,675 | 29 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -1.91% | $1,118,555 | $67.91 | -16,470 | 846,872 | 28 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 1.94% | 16,470 | 863,342 | 28 May 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -17.9% | -16,470 | 75,439 | 28 May 2026 | Direct | ||
| Melissa A. Starovasnik | TWST | Common Stock | Sale | -10.1% | $170,000 | $68.00 | -2,500 | 22,222 | 28 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -2.87% | $1,633,407 | $65.29 | -25,017 | 846,872 | 27 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 2.95% | 25,017 | 871,889 | 27 May 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | 37.4% | 25,017 | 91,909 | 27 May 2026 | Direct | ||
| Melissa A. Starovasnik | TWST | Common Stock | Sale | -1.98% | $30,520 | $61.04 | -500 | 24,722 | 26 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -2.79% | $1,580,246 | $65.08 | -24,282 | 846,872 | 26 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 2.87% | 24,282 | 871,154 | 26 May 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | 26.2% | 24,282 | 116,926 | 26 May 2026 | Direct | ||
| Robert F. Werner | TWST | Common Stock | Sale | -1.63% | $49,987 | $62.48 | -800 | 48,186 | 26 May 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -1.14% | $74,507 | $53.26 | -1,399 | 121,589 | 21 May 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.49% | $221,549 | $53.26 | -4,160 | 274,804 | 21 May 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -1.21% | $87,448 | $53.26 | -1,642 | 134,299 | 21 May 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -1.39% | $36,641 | $53.26 | -688 | 48,986 | 21 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.81% | $366,834 | $53.26 | -6,888 | 846,872 | 21 May 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -1.7% | $107,526 | $53.26 | -2,019 | 116,675 | 21 May 2026 | Direct |
| Jan Johannessen | TWST | Common Stock | Sale | -40.3% | $673,440 | $56.12 | -12,000 | 17,754 | 12 May 2026 | Direct |
| Jan Johannessen | TWST | Common Stock | Options Exercise | 67.6% | 12,000 | 29,754 | 12 May 2026 | Direct | ||
| Jan Johannessen | TWST | Employee Stock Option (right to buy) | Options Exercise | 12,000 | 10,304 | 12 May 2026 | Direct | |||
| Robert F. Werner | TWST | Common Stock | Sale | -9.08% | $282,187 | $56.88 | -4,961 | 49,674 | 08 May 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -1.42% | $112,126 | $57.15 | -1,962 | 135,941 | 04 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.6% | $293,002 | $57.15 | -5,127 | 853,760 | 04 May 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.01% | $162,531 | $57.15 | -2,844 | 278,964 | 04 May 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.9% | $63,778 | $57.15 | -1,116 | 122,988 | 04 May 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -0.3% | $9,372 | $57.15 | -164 | 54,635 | 04 May 2026 | Direct |
| Melissa A. Starovasnik | TWST | Common Stock | Sale | -1.94% | $30,915 | $61.83 | -500 | 25,222 | 27 Apr 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -0.82% | $141,026 | $60.76 | -2,321 | 281,808 | 23 Apr 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.93% | $526,291 | $65.29 | -8,061 | 858,887 | 22 Apr 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 0.94% | 8,061 | 866,948 | 22 Apr 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | 6.05% | 8,061 | 141,208 | 22 Apr 2026 | Direct | ||
| Emily M. Leproust | TWST | Common Stock | Sale | -0.19% | $104,666 | $65.01 | -1,610 | 858,887 | 21 Apr 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 0.19% | 1,610 | 860,497 | 21 Apr 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | 1.09% | 1,610 | 149,269 | 21 Apr 2026 | Direct | ||
| Adam Laponis | TWST | Common Stock | Sale | -3.26% | $240,000 | $60.00 | -4,000 | 118,694 | 17 Apr 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -2.39% | $165,000 | $55.00 | -3,000 | 122,694 | 14 Apr 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -2.02% | $129,562 | $49.89 | -2,597 | 125,694 | 09 Apr 2026 | Direct |
| Melissa A. Starovasnik | TWST | Common Stock | Sale | -3.74% | $51,000 | $51.00 | -1,000 | 25,722 | 01 Apr 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -0.26% | $15,500 | $43.79 | -354 | 137,903 | 20 Mar 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.24% | $13,005 | $43.79 | -297 | 124,104 | 20 Mar 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.2% | $76,276 | $43.79 | -1,742 | 858,887 | 20 Mar 2026 | Direct |
| Robert Chess | TWST | Common Stock | Sale | -32.2% | $470,000 | $47.00 | -10,000 | 21,084 | 17 Mar 2026 | Direct |
| Robert Chess | TWST | Common Stock | Options Exercise | 47.4% | 10,000 | 31,084 | 17 Mar 2026 | Direct | ||
| Robert Chess | TWST | Stock Option (right to buy) | Options Exercise | -35.2% | -10,000 | 18,417 | 17 Mar 2026 | Direct | ||
| Robert F. Werner | TWST | Common Stock | Sale | -0.45% | $11,421 | $46.43 | -246 | 54,799 | 06 Mar 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -0.31% | $19,731 | $46.43 | -425 | 138,257 | 06 Mar 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.75% | $43,408 | $46.43 | -935 | 124,401 | 06 Mar 2026 | Direct |
* marks a reported price that did not pass the local price check.