Comparable stake leader
BlackRock, Inc.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001581280.
Comparable stake leader
BlackRock, Inc.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
21 Aug 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| BlackRock, Inc. |
13F
13D/G
Company
|
8.3%
from 13D/G
|
$600,190,704
5,833,891 shares
|
— | 30 Jun 2026 |
| Artisan Partners Limited Partnership |
13F
13D/G
Company · Artisan Partners Asset Management Inc.
|
7.7%
from 13D/G
|
$494,031,558
4,802,017 shares
|
— | 30 Jun 2026 |
| FMR LLC |
13F
13D/G
Company
|
7.6%
from 13D/G
|
$483,849,178
4,703,044 shares
|
— | 30 Jun 2026 |
| ARK Investment Management LLC |
13F
13D/G
Company
|
7.3%
from 13D/G
|
$468,083,756
4,549,803 shares
|
— | 30 Jun 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
13D/G
Company · T. Rowe Price Associates, Inc.
|
5.8%
from 13D/G
|
$373,934,000
3,634,652 shares
|
— | 30 Jun 2026 |
| STATE STREET CORP |
13F
13D/G
Company · STATE STREET CORPORATION
|
5.1%
from 13D/G
|
$332,562,892
3,232,532 shares
|
— | 30 Jun 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13F
13D/G
Company · Vanguard Capital Management
|
5%
from 13D/G
|
$277,701,926
2,699,280 shares
|
— | 30 Jun 2026 |
| EdgePoint Investment Group Inc. |
13F
13D/G
Company
|
4.2%
from 13D/G
|
$259,425,809
2,521,635 shares
|
— | 30 Jun 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$73,415,298.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 400,846 | $0 | $47,385,688 | -$47,385,688 |
| 3-6 | 0 | 172,255 | $0 | $10,494,746 | -$10,494,746 |
| 6-9 | 0 | 202,134 | $0 | $9,770,579 | -$9,770,579 |
| 9-12 | 0 | 184,935 | $0 | $5,764,285 | -$5,764,285 |
Reporting owners
Showing 1-19 of 19 reporting-owner rows connected to Twist Bioscience Corp. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Emily M. Leproust | Chief Executive Officer, Director | $119,036,011 | -$35,307,068 | -23% | Filing P/S | 25 Aug 2026 |
| Patrick John Finn | President and COO | $29,315,390 | -$17,481,309 | -37% | Filing P/S | 21 Aug 2026 |
| Paula Green | SVP of Human Resources | $16,398,801 | -$5,545,611 | -25% | Filing P/S | 21 Aug 2026 |
| Adam Laponis | Chief Financial Officer | $15,107,156 | -$2,647,994 | -15% | Filing P/S | 21 Aug 2026 |
| William Banyai | Senior Vice President of Advanced Development and General Manager of Data Storage | $12,818,211 | Filing P/S | 03 May 2024 | ||
| Dennis Cho | Senior Vice President, Chief Legal Officer & Corporate Secretary | $10,299,645 | -$7,040,670 | -41% | Filing P/S | 21 Aug 2026 |
| Robert Chess | Director | $6,713,284 | -$2,617,663 | -28% | Mixed | 07 Aug 2026 |
| Robert F. Werner | Chief Accounting Officer | $6,283,684 | -$1,263,982 | -17% | Filing P/S | 21 Aug 2026 |
| Keith Crandell | Director | $3,558,241 | Mixed | 05 Feb 2026 | ||
| James M. Thorburn | Chief Financial Officer | $3,000,970 | Mixed | 02 Jan 2024 | ||
| Katryn Blake | Director | $2,114,519 | -$275,251 | -12% | Filing P/S | 12 Aug 2026 |
| Patrick Weiss | Chief Operating Officer | $1,647,659 | Mixed | 01 Apr 2022 | ||
| Melissa A. Starovasnik | Director | $1,511,096 | -$282,435 | -16% | Filing P/S | 28 May 2026 |
| Nelson Chan | Director | $1,141,839 | Mixed | 05 Feb 2026 | ||
| Xiaoying Mai | Director | $1,086,498 | Mixed | 06 Feb 2024 | ||
| Jan Johannessen | Director | $996,354 | -$953,315 | -49% | Filing P/S | 12 May 2026 |
| Robert P. Ragusa | Director | $995,276 | Mixed | 05 Feb 2026 | ||
| Nicolas Barthelemy | Director | $800,210 | Mixed | 21 Nov 2022 | ||
| Kevin B. Yankton | Chief Accounting Officer | $316,837 | Mixed | 17 May 2023 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Emily M. Leproust | TWST | Common Stock | Sale | -5.12% | $6,317,760 | $151.98 | -41,570 | 770,729 | 25 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -1.88% | $120,220 | $140.77 | -854 | 44,637 | 24 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -2.11% | $222,227 | $139.07 | -1,598 | 74,063 | 21 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.88% | $562,661 | $139.07 | -4,046 | 210,802 | 21 Aug 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -1.14% | $189,130 | $139.07 | -1,360 | 117,921 | 21 Aug 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -1.78% | $273,265 | $139.07 | -1,965 | 108,633 | 21 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.81% | $923,259 | $139.07 | -6,639 | 812,299 | 21 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -1.45% | $93,035 | $139.07 | -669 | 45,491 | 21 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -15.8% | $1,843,099 | $129.75 | -14,205 | 75,661 | 19 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -26.7% | $9,217,607 | $117.64 | -78,355 | 214,678 | 18 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Options Exercise | 8.66% | 23,355 | 293,033 | 18 Aug 2026 | Direct | ||
| Patrick John Finn | TWST | Stock Option (right to buy) | Options Exercise | -100% | -23,355 | 0 | 18 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Common Stock | Sale | -2.38% | $2,495,508 | $125.08 | -19,952 | 818,938 | 12 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 2.44% | 19,952 | 838,890 | 12 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -13% | -19,952 | 133,269 | 12 Aug 2026 | Direct | ||
| Katryn Blake | TWST | Common Stock | Sale | -11.5% | $275,251 | $122.88 | -2,240 | 17,208 | 12 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -12.2% | $14,183,051 | $125.16 | -113,318 | 818,938 | 10 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 13.8% | 113,318 | 932,256 | 10 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -42.5% | -113,318 | 153,221 | 10 Aug 2026 | Direct | ||
| Robert Chess | TWST | Common Stock | Sale | -46.6% | $2,042,261 | $110.89 | -18,417 | 21,084 | 07 Aug 2026 | Direct |
| Robert Chess | TWST | Common Stock | Options Exercise | 87.4% | 18,417 | 39,501 | 07 Aug 2026 | Direct | ||
| Robert Chess | TWST | Stock Option (right to buy) | Options Exercise | -100% | -18,417 | 0 | 07 Aug 2026 | Direct | ||
| Dennis Cho | TWST | Common Stock | Sale | -13.6% | $1,558,999 | $109.75 | -14,205 | 89,866 | 05 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.06% | $246,408 | $85.32 | -2,888 | 269,678 | 03 Aug 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.94% | $96,669 | $85.32 | -1,133 | 119,281 | 03 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.62% | $435,223 | $85.32 | -5,101 | 818,938 | 03 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -0.36% | $14,249 | $85.32 | -167 | 46,160 | 03 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -1.02% | $91,294 | $85.32 | -1,070 | 104,071 | 03 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -0.81% | $210,133 | $93.89 | -2,238 | 272,566 | 23 Jul 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -2.13% | $226,307 | $94.33 | -2,399 | 110,276 | 09 Jul 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -2.24% | $1,793,600 | $95.00 | -18,880 | 824,039 | 25 Jun 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -11.9% | $1,274,899 | $89.75 | -14,205 | 105,141 | 24 Jun 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.24% | $25,411 | $87.32 | -291 | 120,414 | 22 Jun 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -0.29% | $30,214 | $87.32 | -346 | 119,346 | 22 Jun 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.2% | $147,400 | $87.32 | -1,688 | 842,919 | 22 Jun 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -17.8% | $2,134,488 | $81.67 | -26,137 | 120,705 | 15 Jun 2026 | Direct |
| Paula Green | TWST | Common Stock | Options Exercise | 21.6% | 26,137 | 146,842 | 15 Jun 2026 | Direct | ||
| Paula Green | TWST | Employee Stock Option (right to buy) | Options Exercise | -100% | -26,137 | 0 | 15 Jun 2026 | Direct | ||
| Dennis Cho | TWST | Common Stock | Sale | -0.33% | $28,077 | $69.84 | -402 | 119,692 | 08 Jun 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.73% | $61,742 | $69.84 | -884 | 120,705 | 08 Jun 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.27% | $158,197 | $69.84 | -2,265 | 844,607 | 08 Jun 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Gift | -1.07% | -500 | 46,327 | 08 Jun 2026 | Direct | ||
| Robert F. Werner | TWST | Common Stock | Sale | -2.82% | $94,046 | $69.20 | -1,359 | 46,827 | 08 Jun 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -10.6% | $990,799 | $69.75 | -14,205 | 120,094 | 29 May 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -3.43% | $280,000 | $70.00 | -4,000 | 112,675 | 29 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -1.91% | $1,118,555 | $67.91 | -16,470 | 846,872 | 28 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 1.94% | 16,470 | 863,342 | 28 May 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -17.9% | -16,470 | 75,439 | 28 May 2026 | Direct | ||
| Melissa A. Starovasnik | TWST | Common Stock | Sale | -10.1% | $170,000 | $68.00 | -2,500 | 22,222 | 28 May 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -2.87% | $1,633,407 | $65.29 | -25,017 | 846,872 | 27 May 2026 | Direct |