Comparable stake leader
FMR LLC
SEC ownership of Twist Bioscience Corp
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001581280.
Disclosed value leader
FMR LLC
Comparable rows
10/50
Latest evidence
05 Oct 2026
- Public ticker
- TWST on Nasdaq
- Parsed ownership sources
-
13D/G, 13F, and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
- Largest SEC-reported holder
-
FMR LLC
Ranking: Comparable ownership first, then disclosed value
- Comparable ownership rows
-
10 of 50
Meaning: Rows with safely comparable ownership %
- Latest 13D/G holder
-
FMR LLC
Source: Latest parsed Schedule 13D/G stake
- Latest parsed ownership date
-
05 Oct 2026
Freshness: Most recent filing date in this holder set
- Issuer CIK
- 0001581280
- Issuer location
- South San Francisco, CA
Ownership snapshot
CIK-linked ownership evidence from parsed SEC filings.
3 signals
Issuer
Names, identifiers, and filing context for this profile.
2 identity fields
Ownership snapshot
Top shareholders of Twist Bioscience Corp (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Comparable stake leader
FMR LLC
Disclosed value leader
FMR LLC
Comparable rows
10/50
Latest evidence
05 Oct 2026
13D/G
13F
3/4/5
Lead comparable stake: 13%
40 rows are not safely comparable across share classes.
13D/G row: FMR LLC
Showing 1-8 of 50 holder rows.
Quick read
FMR LLC leads the comparable SEC ownership view at 13%.
10 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Open SEC evidence
Opens FMR LLC's linked filing trail.
Comparable ownership
Top 5
FMR LLC
13%
BlackRock, Inc.
8.3%
Artisan Partners Limited Partnership
7.7%
PRICE T ROWE ASSOCIATES INC /MD/
5.8%
ARK Investment Management LLC
5.1%
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
Detailed SEC evidence table Showing 1-8 of 50 holder rows
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| FMR LLC |
13D/G
13F
Company
|
13%
Reported 13D/G
· 31 Aug 2026
|
$1,097,550,605
8,760,081 shares
|
+$508,306,166 | 31 Aug 2026 |
| BlackRock, Inc. |
13F
13D/G
Company
|
8.3%
Reported 13D/G
· 31 Mar 2025
|
$600,190,704
5,833,891 shares
|
— | 30 Jun 2026 |
| Artisan Partners Limited Partnership |
13F
13D/G
Company · Artisan Partners Asset Management Inc.
|
7.7%
Reported 13D/G
· 30 Jun 2026
|
$494,031,558
4,802,017 shares
|
— | 30 Jun 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
13D/G
Company · T. Rowe Price Associates, Inc.
|
5.8%
Reported 13D/G
· 30 Jun 2026
|
$373,934,000
3,634,652 shares
|
— | 30 Jun 2026 |
| ARK Investment Management LLC |
13F
13D/G
Company
|
5.1%
Reported 13D/G
· 31 Aug 2026
|
$468,083,756
4,549,803 shares
|
— | 30 Jun 2026 |
| STATE STREET CORP |
13F
13D/G
Company · STATE STREET CORPORATION
|
5.1%
Reported 13D/G
· 30 Sep 2025
|
$332,562,892
3,232,532 shares
|
— | 30 Jun 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13F
13D/G
Company · Vanguard Capital Management
|
5%
Reported 13D/G
· 31 Mar 2026
|
$277,701,926
2,699,280 shares
|
— | 30 Jun 2026 |
| EdgePoint Investment Group Inc. |
13F
13D/G
Company
|
4.2%
Reported 13D/G
· 30 Jun 2026
|
$259,425,809
2,521,635 shares
|
— | 30 Jun 2026 |
How to read this table
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Insider trading overview
Net insider flow leans to selling over the last 12 months. Net value: -$146,881,876.
Buys
$0
Insiders: 0
Sells
$146,881,876
Insiders: 10
Net
-$146,881,876
Shares: -1,268,449
Window
Last 12 months
4 rolling buckets
Buy value
Sell value
Shares: 0
Shares: 1,268,449
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 783,626 | $0 | $117,607,978 | -$117,607,978 |
| 3-6 | 0 | 217,189 | $0 | $16,330,999 | -$16,330,999 |
| 6-9 | 0 | 198,315 | $0 | $10,313,532 | -$10,313,532 |
| 9-12 | 0 | 69,319 | $0 | $2,629,367 | -$2,629,367 |
Reporting owners
Insider holders from Forms 3/4/5
Showing 1-19 of 19 reporting-owner rows connected to Twist Bioscience Corp. Open a relationship link for the CIK-to-CIK filing trail.
Rows
19
Largest Forms 3/4/5 holder
Emily M. Leproust
Net 12M change
-$146.88M
Full value: -$146,881,877 · USD · 12-month changeLatest report
23 Oct 2026
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Emily M. Leproust | Chief Executive Officer, Director | $129,298,670 | -$100,539,685 | -44% | Mixed | 05 Oct 2026 |
| Patrick John Finn | President and COO | $24,608,656 | -$21,158,926 | -46% | Filing P/S | 23 Oct 2026 |
| Paula Green | SVP of Human Resources | $20,141,078 | -$7,010,401 | -26% | Filing P/S | 02 Oct 2026 |
| Adam Laponis | Chief Financial Officer | $15,335,698 | -$4,015,764 | -21% | Filing P/S | 09 Oct 2026 |
| William Banyai | Senior Vice President of Advanced Development and General Manager of Data Storage | $12,818,211 | Filing P/S | 03 May 2024 | ||
| Dennis Cho | Senior Vice President, Chief Legal Officer & Corporate Secretary | $12,048,721 | -$8,564,172 | -42% | Filing P/S | 02 Oct 2026 |
| Robert F. Werner | Chief Accounting Officer | $8,106,334 | -$1,464,265 | -15% | Filing P/S | 02 Oct 2026 |
| Robert Chess | Director | $6,713,284 | -$2,617,663 | -28% | Mixed | 07 Aug 2026 |
| Keith Crandell | Director | $3,558,241 | Mixed | 05 Feb 2026 | ||
| James M. Thorburn | Chief Financial Officer | $3,000,970 | Mixed | 02 Jan 2024 | ||
| Katryn Blake | Director | $2,114,519 | -$275,251 | -12% | Filing P/S | 12 Aug 2026 |
| Patrick Weiss | Chief Operating Officer | $1,647,659 | Mixed | 01 Apr 2022 | ||
| Melissa A. Starovasnik | Director | $1,511,096 | -$282,435 | -16% | Filing P/S | 28 May 2026 |
| Nelson Chan | Director | $1,141,839 | Mixed | 05 Feb 2026 | ||
| Xiaoying Mai | Director | $1,086,498 | Mixed | 06 Feb 2024 | ||
| Jan Johannessen | Director | $996,354 | -$953,315 | -49% | Filing P/S | 12 May 2026 |
| Robert P. Ragusa | Director | $995,276 | Mixed | 05 Feb 2026 | ||
| Nicolas Barthelemy | Director | $800,210 | Mixed | 21 Nov 2022 | ||
| Kevin B. Yankton | Chief Accounting Officer | $316,837 | Mixed | 17 May 2023 |
Recent insider transactions for Twist Bioscience Corp
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Patrick John Finn | TWST | Common Stock | Sale | -1.21% | -$302,152 | $134.59 | -2,245 | 182,843 | 23 Oct 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -2.45% | -$384,823 | $156.30 | -2,462 | 98,114 | 09 Oct 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.8% | -$919,374 | $202.15 | -4,548 | 562,760 | 05 Oct 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -7.42% | -$1,521,838 | $188.88 | -8,057 | 100,576 | 02 Oct 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -8.64% | -$1,905,462 | $188.88 | -10,088 | 106,632 | 02 Oct 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -12.2% | -$4,856,963 | $188.88 | -25,714 | 185,088 | 02 Oct 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -7.46% | -$8,638,799 | $188.88 | -45,736 | 567,308 | 02 Oct 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -13% | -$1,797,042 | $188.88 | -9,514 | 63,789 | 02 Oct 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -3.34% | -$279,926 | $188.88 | -1,482 | 42,917 | 02 Oct 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.11% | -$131,000 | $200.00 | -655 | 613,044 | 01 Oct 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.84% | -$922,907 | $177.38 | -5,203 | 613,699 | 24 Sep 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -0.47% | -$57,591 | $165.49 | -348 | 73,303 | 21 Sep 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.25% | -$48,654 | $165.49 | -294 | 116,720 | 21 Sep 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.27% | -$279,183 | $165.49 | -1,687 | 618,902 | 21 Sep 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -36.5% | -$56,330,724 | $157.99 | -356,546 | 620,589 | 17 Sep 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 27.2% | 208,708 | 977,135 | 17 Sep 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -100% | -208,708 | 0 | 17 Sep 2026 | Direct | ||
| Dennis Cho | TWST | Common Stock | Sale | -0.56% | -$50,521 | $122.62 | -412 | 73,651 | 08 Sep 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.77% | -$111,220 | $122.62 | -907 | 117,014 | 08 Sep 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.3% | -$282,280 | $122.62 | -2,302 | 768,427 | 08 Sep 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -0.53% | -$29,185 | $122.62 | -238 | 44,399 | 08 Sep 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -5.12% | -$6,317,760 | $151.98 | -41,570 | 770,729 | 25 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -1.88% | -$120,220 | $140.77 | -854 | 44,637 | 24 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -2.11% | -$222,227 | $139.07 | -1,598 | 74,063 | 21 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.88% | -$562,661 | $139.07 | -4,046 | 210,802 | 21 Aug 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -1.14% | -$189,130 | $139.07 | -1,360 | 117,921 | 21 Aug 2026 | Direct |
| Adam Laponis | TWST | Common Stock | Sale | -1.78% | -$273,265 | $139.07 | -1,965 | 108,633 | 21 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.81% | -$923,259 | $139.07 | -6,639 | 812,299 | 21 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -1.45% | -$93,035 | $139.07 | -669 | 45,491 | 21 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -15.8% | -$1,843,099 | $129.75 | -14,205 | 75,661 | 19 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -26.7% | -$9,217,607 | $117.64 | -78,355 | 214,678 | 18 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Options Exercise | 8.66% | 23,355 | 293,033 | 18 Aug 2026 | Direct | ||
| Patrick John Finn | TWST | Stock Option (right to buy) | Options Exercise | -100% | -23,355 | 0 | 18 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Common Stock | Sale | -2.38% | -$2,495,508 | $125.08 | -19,952 | 818,938 | 12 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 2.44% | 19,952 | 838,890 | 12 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -13% | -19,952 | 133,269 | 12 Aug 2026 | Direct | ||
| Katryn Blake | TWST | Common Stock | Sale | -11.5% | -$275,251 | $122.88 | -2,240 | 17,208 | 12 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -12.2% | -$14,183,051 | $125.16 | -113,318 | 818,938 | 10 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Options Exercise | 13.8% | 113,318 | 932,256 | 10 Aug 2026 | Direct | ||
| Emily M. Leproust | TWST | Employee Stock Option (right to buy) | Options Exercise | -42.5% | -113,318 | 153,221 | 10 Aug 2026 | Direct | ||
| Robert Chess | TWST | Common Stock | Sale | -46.6% | -$2,042,261 | $110.89 | -18,417 | 21,084 | 07 Aug 2026 | Direct |
| Robert Chess | TWST | Common Stock | Options Exercise | 87.4% | 18,417 | 39,501 | 07 Aug 2026 | Direct | ||
| Robert Chess | TWST | Stock Option (right to buy) | Options Exercise | -100% | -18,417 | 0 | 07 Aug 2026 | Direct | ||
| Dennis Cho | TWST | Common Stock | Sale | -13.6% | -$1,558,999 | $109.75 | -14,205 | 89,866 | 05 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -1.06% | -$246,408 | $85.32 | -2,888 | 269,678 | 03 Aug 2026 | Direct |
| Paula Green | TWST | Common Stock | Sale | -0.94% | -$96,669 | $85.32 | -1,133 | 119,281 | 03 Aug 2026 | Direct |
| Emily M. Leproust | TWST | Common Stock | Sale | -0.62% | -$435,223 | $85.32 | -5,101 | 818,938 | 03 Aug 2026 | Direct |
| Robert F. Werner | TWST | Common Stock | Sale | -0.36% | -$14,249 | $85.32 | -167 | 46,160 | 03 Aug 2026 | Direct |
| Dennis Cho | TWST | Common Stock | Sale | -1.02% | -$91,294 | $85.32 | -1,070 | 104,071 | 03 Aug 2026 | Direct |
| Patrick John Finn | TWST | Common Stock | Sale | -0.81% | -$210,133 | $93.89 | -2,238 | 272,566 | 23 Jul 2026 | Direct |
* marks a reported price that did not pass the local price check.