| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Artisan Partners Limited Partnership | 11% | +28% | $180,403,367 | +$37,985,392 | 6,410,900 | +27% | Artisan Partners Asset Management Inc. | 30 Sep 2025 |
| ARK Investment Management LLC | 11% | +17% | $256,371,608 | +$41,137,012 | 6,382,166 | +19% | ARK Investment Management LLC | 28 Feb 2025 |
| BlackRock, Inc. | 8.3% | $197,947,718 | 4,927,750 | BlackRock, Inc. | 31 Mar 2025 | |||
| EdgePoint Investment Group Inc. | 6.8% | $114,876,457 | 4,082,319 | EdgePoint Investment Group Inc. | 30 Sep 2025 | |||
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 6.4% | +28% | $152,921,847 | +$34,431,474 | 3,806,867 | +29% | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 31 Mar 2025 |
| STATE STREET CORP | 5.1% | +20% | $86,926,233 | +$15,338,157 | 3,089,063 | +21% | STATE STREET CORPORATION | 30 Sep 2025 |
| Invesco Ltd. | 3.9% | $91,850,982 | 2,347,929 | Invesco Ltd. | 30 Jun 2025 |
As of 30 Sep 2025, 233 institutional investors reported holding 73,760,956 shares of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST). This represents 122% of the company’s total 60,389,334 outstanding shares.
The largest institutional shareholders of Twist Bioscience Corp - Common stock, $0.00001 par value per share (TWST) together control 100% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| ARK Investment Management LLC | 11% | 6,726,808 | +5.1% | 1.1% | $189,292,386 |
| Artisan Partners Limited Partnership | 11% | 6,410,900 | +27% | 0.26% | $180,402,726 |
| BlackRock, Inc. | 10% | 6,178,376 | -1.6% | 0% | $173,859,502 |
| VANGUARD GROUP INC | 9.6% | 5,768,149 | -1.1% | 0% | $162,315,713 |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 6.9% | 4,142,283 | +6% | 0.3% | $116,563,844 |
| EdgePoint Investment Group Inc. | 6.8% | 4,082,319 | +71% | 0.86% | $114,876,457 |
| STATE STREET CORP | 5.1% | 3,089,063 | +24% | 0% | $86,926,233 |
| Sumitomo Mitsui Trust Group, Inc. | 3.5% | 2,120,206 | -7.8% | 0.03% | $59,662,597 |
| Amova Asset Management Americas, Inc. | 3.5% | 2,120,206 | -7.8% | 0.58% | $59,641,395 |
| Soleus Capital Management, L.P. | 3.1% | 1,866,234 | +427% | 2.8% | $52,515,825 |
| Invesco Ltd. | 3% | 1,795,143 | -24% | 0.01% | $50,515,324 |
| MILLENNIUM MANAGEMENT LLC | 3% | 1,793,850 | +152% | 0.04% | $50,478,939 |
| GOLDMAN SACHS GROUP INC | 2.7% | 1,627,020 | +6.7% | 0.01% | $45,784,343 |
| MORGAN STANLEY | 2.5% | 1,492,106 | +24% | 0% | $41,987,888 |
| Thrivent Financial for Lutherans | 2.4% | 1,463,085 | +14% | 0.08% | $41,171,000 |
| GEODE CAPITAL MANAGEMENT, LLC | 2.4% | 1,448,413 | +1.7% | 0% | $40,764,323 |
| BAILLIE GIFFORD & CO | 2.1% | 1,262,739 | +63% | 0.03% | $35,533,475 |
| First Light Asset Management, LLC | 2% | 1,194,883 | +26% | 3.2% | $33,624,008 |
| UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC | 1.9% | 1,123,697 | -7.8% | 0.01% | $31,620,833 |
| JPMORGAN CHASE & CO | 1.7% | 1,018,234 | -29% | 0% | $28,653,105 |
| AMERICAN CENTURY COMPANIES INC | 1.4% | 838,064 | -3% | 0.01% | $23,583,186 |
| Tao Capital Management LP | 1.4% | 828,815 | 0% | 18% | $23,322,854 |
| DIMENSIONAL FUND ADVISORS LP | 1.3% | 790,893 | +8.6% | 0% | $22,252,035 |
| JENNISON ASSOCIATES LLC | 1.1% | 634,600 | +2.6% | 0.01% | $17,857,642 |
| NEW YORK STATE COMMON RETIREMENT FUND | 0.97% | 584,694 | +14% | 0.02% | $16,453,289 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 77,115 | $2,446,015 | +$1,894,527 | $31.72 | 4 |
| 2025 Q3 | 73,760,956 | $2,075,454,827 | +$57,819,086 | $28.14 | 233 |
| 2025 Q2 | 71,133,390 | $2,616,814,853 | +$58,445,660 | $36.79 | 240 |
| 2025 Q1 | 69,532,083 | $2,729,868,536 | +$98,718,253 | $39.26 | 260 |
| 2024 Q4 | 66,360,913 | $3,083,489,168 | +$6,148,856 | $46.47 | 244 |
| 2024 Q3 | 66,073,350 | $2,986,931,967 | -$9,670,153 | $45.18 | 240 |
| 2024 Q2 | 65,972,475 | $3,251,056,592 | +$28,344,193 | $49.28 | 256 |
| 2024 Q1 | 67,075,830 | $2,301,195,873 | +$12,173,886 | $34.31 | 230 |
| 2023 Q4 | 66,744,591 | $2,459,763,309 | +$20,095,641 | $36.86 | 215 |
| 2023 Q3 | 66,341,769 | $1,344,049,066 | -$31,879,539 | $20.26 | 191 |
| 2023 Q2 | 68,103,043 | $1,393,371,812 | +$106,475,508 | $20.46 | 185 |
| 2023 Q1 | 63,810,827 | $961,273,962 | +$17,347,246 | $15.08 | 197 |
| 2022 Q4 | 62,336,899 | $1,484,114,188 | +$31,639,333 | $23.81 | 191 |
| 2022 Q3 | 59,850,512 | $2,097,211,101 | +$44,899,500 | $35.24 | 206 |
| 2022 Q2 | 57,994,411 | $2,008,438,723 | -$90,076,201 | $34.96 | 188 |
| 2022 Q1 | 54,121,106 | $2,662,382,357 | +$281,218,717 | $49.38 | 193 |
| 2021 Q4 | 51,230,952 | $3,958,124,330 | +$152,934,374 | $77.39 | 224 |
| 2021 Q3 | 48,658,857 | $5,195,018,312 | +$41,898,607 | $106.97 | 229 |
| 2021 Q2 | 48,123,755 | $6,401,051,212 | +$152,118,907 | $133.25 | 240 |
| 2021 Q1 | 46,988,226 | $5,820,040,994 | +$482,887,437 | $123.86 | 234 |
| 2020 Q4 | 42,909,917 | $6,062,828,297 | +$547,775,260 | $141.29 | 215 |
| 2020 Q3 | 39,702,868 | $3,018,023,941 | +$217,077,489 | $75.97 | 191 |
| 2020 Q2 | 37,011,859 | $1,675,114,837 | +$285,296,567 | $45.30 | 141 |
| 2020 Q1 | 30,828,177 | $943,220,817 | +$343,349,207 | $30.58 | 116 |
| 2019 Q4 | 19,740,464 | $414,547,368 | +$39,243,468 | $21.00 | 92 |
| 2019 Q3 | 15,673,899 | $374,288,352 | +$37,099,334 | $23.88 | 82 |
| 2019 Q2 | 13,908,043 | $401,736,443 | +$231,712,763 | $29.01 | 83 |
| 2019 Q1 | 6,003,624 | $137,709,000 | -$1,684,002 | $23.18 | 47 |
| 2018 Q4 | 6,077,977 | $137,438,000 | +$137,438,002 | $23.09 | 46 |