SEC ownership of Acumen Pharmaceuticals, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001576885.

Holder evidence

50

Lead holder

RA CAPITAL MANAGEMENT, L.P.

13D/G signal

RA CAPITAL MANAGEMENT, L.P.

Latest evidence

31 Mar 2026

Issuer identity
CIK
0001576885
Location
Newton, MA
Ownership snapshot
Latest large-stake holder
RA CAPITAL MANAGEMENT, L.P.
Latest evidence date
31 Mar 2026

Ownership snapshot

Top shareholders of Acumen Pharmaceuticals, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Lead holder
RA CAPITAL MANAGEMENT, L.P.
13D/G signal
RA CAPITAL MANAGEMENT, L.P.
Evidence rows
50
Latest as of
31 Mar 2026
13D/G 3/4/5 13F Lead comparable stake: 30% 13D/G row: RA CAPITAL MANAGEMENT, L.P. Showing 1-8 of 50 holder rows.
Holder Evidence Ownership % Position 12M Net Δ As of
RA CAPITAL MANAGEMENT, L.P.
13D/G 3/4/5 13F
Director, 10%+ Owner · Company
30%
$55,075,356
21,101,669 shares
+$15,883,432 13 Mar 2026
Sands Capital Alternatives, LLC
13F 13D/G
Company
5.6%
from 13D/G
$8,779,448
3,720,105 shares
31 Mar 2026
James B. Murray Jr.
13D/G
5%
$9,425,650
3,611,360 shares
$0 04 Apr 2025
FRANKLIN RESOURCES INC
13F 13D/G
Company
3.8%
from 13D/G
$5,440,027
2,305,096 shares
31 Mar 2026
Alyeska Investment Group, L.P.
13F
Company
13F
3.4%
$5,776,765
2,454,754 shares
31 Mar 2026
ADAR1 Capital Management, LLC
13F
Company
13F
3%
$5,088,948
2,156,334 shares
31 Mar 2026
Knollwood Investment Advisory, LLC
13F
Company
13F
2.3%
$3,843,284
1,628,510 shares
31 Mar 2026
VANGUARD CAPITAL MANAGEMENT LLC
13F
Company
13F
2.1%
$3,554,814
1,506,277 shares
31 Mar 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$535,919.

Buys
$0
Insiders: 0
Sells
$535,919
Insiders: 7
Net
-$535,919
Shares: -266,428
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 266,428
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 2,090 $0 $6,813 -$6,813
3-6 0 264,338 $0 $529,105 -$529,105
6-9 0 0 $0 $0 $0
9-12 0 0 $0 $0 $0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-19 of 19 reporting-owner rows connected to Acumen Pharmaceuticals, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
19
Lead holder
RA CAPITAL MANAGEMENT, L.P.
Net 12M change
-$535,918
Latest report
16 Mar 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
RA CAPITAL MANAGEMENT, L.P. Director, 10%+ Owner $49,860,878 Mixed 16 Mar 2026
Sands Capital Ventures Discovery Fund III, L.P. 10%+ Owner $11,859,300 Mixed 06 Jul 2021
Paul B. Manning 10%+ Owner $2,283,603 Mixed 06 Jul 2021
Robert D. Hardie 10%+ Owner $2,283,603 Mixed 06 Jul 2021
Daniel Joseph OConnell Chief Executive Officer, Director $1,660,145 -$163,123 -8.9% Filing P/S 21 Jan 2026
Derek M. Meisner Chief Legal Officer & Corp Sec $567,236 -$248,888 -30% Filing P/S 06 Mar 2026
Matt Zuga CFO & Chief Business Officer $567,158 -$49,556 -8% Filing P/S 21 Jan 2026
James J. Doherty President and CDO $466,054 -$15,148 -3.1% Mixed 16 Jan 2026
Eric Siemers Chief Medical Officer $464,775 -$27,110 -5.5% Filing P/S 21 Jan 2026
Russell Barton Chief Operating Officer $377,369 -$29,917 -7.3% Filing P/S 21 Jan 2026
John A. Stalfort III Director $203,636 Mixed 04 Jun 2025
Amy Schacterle Chief Regulatory Officer $194,740 -$2,176 -1.1% Mixed 16 Jan 2026
Nathan B. Fountain Director $20,955 Mixed 04 Jun 2025
Laura Stoppel Director $14,080 Mixed 04 Jun 2025
Kimberlee C. Drapkin Director $14,080 Mixed 04 Jun 2025
Derrell Porter Director $14,080 Mixed 04 Jun 2025
Jeffrey L. Ives Director $14,080 Mixed 04 Jun 2025
George Golumbeski Director Mixed 06 Nov 2025
Jeffrey Sevigny Director Mixed 15 Jun 2022

Recent insider transactions for Acumen Pharmaceuticals, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % Reported value Reported price Shares Shares owned Date Ownership
Ra Capital Management, L.P. ABOS Common Stock Award 46.5% 6,060,606 19,103,785 16 Mar 2026 See footnotes
Derek M. Meisner ABOS Common Stock Sale -1.19% $6,813 $3.26 -2,090 173,999 06 Mar 2026 Direct
Derek M. Meisner ABOS Common Stock Options Exercise 1.2% 2,090 176,089 06 Mar 2026 Direct
Derek M. Meisner ABOS Employee Stock Option (right to buy) Options Exercise -2.86% -2,090 71,048 06 Mar 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -5.13% $28,311 $3.01 -9,406 173,999 27 Feb 2026 Direct
Derek M. Meisner ABOS Common Stock Options Exercise 5.41% 9,406 183,405 27 Feb 2026 Direct
Derek M. Meisner ABOS Employee Stock Option (right to buy) Options Exercise -11.4% -9,406 73,138 27 Feb 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -1.51% $8,017 $3.00 -2,671 173,999 28 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Options Exercise 1.54% 2,671 176,670 28 Jan 2026 Direct
Derek M. Meisner ABOS Employee Stock Option (right to buy) Options Exercise -3.13% -2,671 82,544 28 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -7.98% $45,263 $3.00 -15,085 173,999 26 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Options Exercise 8.67% 15,085 189,084 26 Jan 2026 Direct
Derek M. Meisner ABOS Employee Stock Option (right to buy) Options Exercise -15% -15,085 85,215 26 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -3.14% $10,718 $1.90 -5,633 173,999 23 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -0.58% $1,939 $1.84 -1,054 179,632 22 Jan 2026 Direct
Eric Siemers ABOS Common Stock Sale -0.35% $1,629 $1.82 -895 255,371 22 Jan 2026 Direct
Matt Zuga ABOS Common Stock Sale -0.55% $3,138 $1.86 -1,687 304,924 22 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Sale -0.3% $5,066 $1.88 -2,689 881,275 22 Jan 2026 Direct
Russell Barton ABOS Common Stock Sale -0.22% $850 $1.84 -462 205,092 22 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -1.23% $4,063 $1.81 -2,247 180,686 21 Jan 2026 Direct
Eric Siemers ABOS Common Stock Sale -0.9% $4,204 $1.80 -2,331 256,266 21 Jan 2026 Direct
Matt Zuga ABOS Common Stock Sale -0.8% $4,469 $1.81 -2,473 306,611 21 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Sale -1.05% $16,927 $1.81 -9,346 883,964 21 Jan 2026 Direct
Russell Barton ABOS Common Stock Sale -1.11% $4,181 $1.81 -2,315 205,554 21 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Award 50.5% 299,800 893,310 20 Jan 2026 Direct
Daniel Joseph OConnell ABOS Employee Stock Option (right to buy) Award 450,000 450,000 20 Jan 2026 Direct
Matt Zuga ABOS Common Stock Award 47.2% 99,133 309,084 16 Jan 2026 Direct
Matt Zuga ABOS Employee Stock Option (right to buy) Award 148,700 148,700 16 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Award 118.3% 99,133 182,933 16 Jan 2026 Direct
Derek M. Meisner ABOS Employee Stock Option (right to buy) Award 148,700 148,700 16 Jan 2026 Direct
Eric Siemers ABOS Common Stock Award 62.2% 99,133 258,597 16 Jan 2026 Direct
Eric Siemers ABOS Employee Stock Option (right to buy) Award 148,700 148,700 16 Jan 2026 Direct
Russell Barton ABOS Common Stock Award 68.6% 84,600 207,869 16 Jan 2026 Direct
Russell Barton ABOS Employee Stock Option (right to buy) Award 126,900 126,900 16 Jan 2026 Direct
Amy Schacterle ABOS Common Stock Award 1098.3% 84,600 92,303 16 Jan 2026 Direct
Amy Schacterle ABOS Employee Stock Option (right to buy) Award 126,900 126,900 16 Jan 2026 Direct
James J. Doherty ABOS Common Stock Award 308.8% 166,867 220,900 16 Jan 2026 Direct
James J. Doherty ABOS Employee Stock Option (right to buy) Award 250,300 250,300 16 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -9.26% $14,658 $1.71 -8,548 83,800 12 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Sale -0.9% $9,307 $1.73 -5,388 593,510 12 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -5.33% $9,169 $1.76 -5,200 92,348 09 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Sale -2.12% $22,832 $1.76 -12,941 598,898 09 Jan 2026 Direct
Matt Zuga ABOS Common Stock Sale -3.18% $12,513 $1.82 -6,888 209,951 08 Jan 2026 Direct
Russell Barton ABOS Common Stock Sale -2.78% $6,562 $1.86 -3,530 123,269 08 Jan 2026 Direct
Derek M. Meisner ABOS Common Stock Sale -27.4% $67,246 $1.82 -36,911 97,548 08 Jan 2026 Direct
Daniel Joseph OConnell ABOS Common Stock Sale -1.31% $14,815 $1.82 -8,143 611,839 08 Jan 2026 Direct
James J. Doherty ABOS Common Stock Sale -10.7% $11,769 $1.82 -6,467 54,033 08 Jan 2026 Direct
James J. Doherty ABOS Common Stock Sale -2.73% $3,379 $1.99 -1,700 60,500 07 Jan 2026 Direct
Amy Schacterle ABOS Common Stock Sale -12.5% $2,176 $1.98 -1,097 7,703 07 Jan 2026 Direct
Matt Zuga ABOS Common Stock Sale -2.61% $11,566 $1.99 -5,805 216,839 07 Jan 2026 Direct
* indicates a reported price that failed the local validity check.
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