Comparable stake leader
RA CAPITAL MANAGEMENT, L.P.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001576885.
Comparable stake leader
RA CAPITAL MANAGEMENT, L.P.
Disclosed value leader
RA CAPITAL MANAGEMENT, L.P.
Comparable rows
50/50
Latest evidence
15 Jun 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. |
13D/G
3/4/5
13F
Director, 10%+ Owner · Company
|
30%
|
$55,075,356
21,101,669 shares
|
+$15,883,432 | 13 Mar 2026 |
| Sands Capital Alternatives, LLC |
13F
13D/G
Company
|
5.6%
from 13D/G
|
$8,779,448
3,720,105 shares
|
— | 31 Mar 2026 |
| James B. Murray Jr. |
13D/G
|
5%
|
$9,425,650
3,611,360 shares
|
$0 | 04 Apr 2025 |
| FRANKLIN RESOURCES INC |
13F
13D/G
Company
|
3.8%
from 13D/G
|
$5,440,027
2,305,096 shares
|
— | 31 Mar 2026 |
| Derrell Porter |
3/4/5
Director
|
0.05%
|
$82,537
35,500 shares
|
-$75,240 | 15 Jun 2026 |
| Alyeska Investment Group, L.P. |
13F
Company
|
3.4%
|
$5,776,765
2,454,754 shares
|
— | 31 Mar 2026 |
| ADAR1 Capital Management, LLC |
13F
Company
|
3%
|
$5,088,948
2,156,334 shares
|
— | 31 Mar 2026 |
| Knollwood Investment Advisory, LLC |
13F
Company
|
2.3%
|
$3,843,284
1,628,510 shares
|
— | 31 Mar 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$625,431.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 38,700 | $0 | $89,512 | -$89,512 |
| 3-6 | 0 | 11,496 | $0 | $35,125 | -$35,125 |
| 6-9 | 0 | 254,932 | $0 | $500,794 | -$500,794 |
| 9-12 | 0 | 0 | $0 | $0 | $0 |
Reporting owners
Showing 1-20 of 23 reporting-owner rows connected to Acumen Pharmaceuticals, Inc.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Sands Capital Ventures Discovery Fund III, L.P. | 10%+ Owner | $11,859,300 | Mixed | 06 Jul 2021 | ||
| Paul B. Manning | 10%+ Owner | $2,283,603 | Mixed | 06 Jul 2021 | ||
| Robert D. Hardie | 10%+ Owner | $2,283,603 | Mixed | 06 Jul 2021 | ||
| Daniel Joseph OConnell | Chief Executive Officer, Director | $1,660,145 | -$163,123 | -8.9% | Filing P/S | 21 Jan 2026 |
| Derek M. Meisner | Chief Legal Officer & Corp Sec | $567,236 | -$248,888 | -30% | Filing P/S | 06 Mar 2026 |
| Matt Zuga | CFO & Chief Business Officer | $567,158 | -$49,556 | -8% | Filing P/S | 21 Jan 2026 |
| John A. Stalfort III | Director | $520,672 | Mixed | 03 Jun 2026 | ||
| James J. Doherty | President and CDO | $466,054 | -$15,148 | -3.1% | Mixed | 16 Jan 2026 |
| Eric Siemers | Chief Medical Officer | $464,775 | -$27,110 | -5.5% | Filing P/S | 21 Jan 2026 |
| Russell Barton | Chief Operating Officer | $377,369 | -$29,917 | -7.3% | Filing P/S | 21 Jan 2026 |
| Amy Schacterle | Chief Regulatory Officer | $194,740 | -$2,176 | -1.1% | Mixed | 16 Jan 2026 |
| RA Capital Healthcare Fund LP | Director, 10%+ Owner | $113,988 | Mixed | 03 Jun 2026 | ||
| Laura Stoppel | Director | $113,988 | Mixed | 03 Jun 2026 | ||
| Rajeev M. Shah | Director, 10%+ Owner | $113,988 | Mixed | 03 Jun 2026 | ||
| Kimberlee C. Drapkin | Director | $113,988 | Mixed | 03 Jun 2026 | ||
| Jeffrey L. Ives | Director | $113,988 | Mixed | 03 Jun 2026 | ||
| Peter Kolchinsky | Director, 10%+ Owner | $113,988 | Mixed | 03 Jun 2026 | ||
| RA Capital Nexus Fund II, L.P. | Director | $113,988 | Mixed | 03 Jun 2026 | ||
| RA CAPITAL MANAGEMENT, L.P. | Director, 10%+ Owner | $113,988 | Mixed | 03 Jun 2026 | ||
| Nathan B. Fountain | Director | $107,379 | -$14,273 | -12% | Filing P/S | 09 Jun 2026 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Derrell Porter | ABOS | Common Stock | Sale | -26.9% | $30,318 | $2.32 | -13,040 | 35,500 | 17 Jun 2026 | Direct |
| Derrell Porter | ABOS | Common Stock | Options Exercise | 36.7% | 13,040 | 48,540 | 17 Jun 2026 | Direct | ||
| Derrell Porter | ABOS | Stock Option (right to buy) | Options Exercise | -100% | -13,040 | 0 | 17 Jun 2026 | Direct | ||
| Derrell Porter | ABOS | Common Stock | Sale | -26.5% | $29,773 | $2.33 | -12,800 | 35,500 | 16 Jun 2026 | Direct |
| Derrell Porter | ABOS | Common Stock | Sale | -11.8% | $15,149 | $2.34 | -6,460 | 48,300 | 15 Jun 2026 | Direct |
| Derrell Porter | ABOS | Common Stock | Options Exercise | 13.4% | 6,460 | 54,760 | 15 Jun 2026 | Direct | ||
| Derrell Porter | ABOS | Stock Option (right to buy) | Options Exercise | -33.1% | -6,460 | 13,040 | 15 Jun 2026 | Direct | ||
| Nathan B. Fountain | ABOS | Common Stock | Sale | -11.7% | $14,273 | $2.23 | -6,400 | 48,150 | 09 Jun 2026 | Direct |
| RA CAPITAL MANAGEMENT, L.P. | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | See footnotes | ||
| RA CAPITAL MANAGEMENT, L.P. | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | See footnotes | ||
| Ra Capital Management, L.P. | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | See footnotes | ||
| Ra Capital Management, L.P. | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | See footnotes | ||
| Ra Capital Management, L.P. | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | See footnotes | ||
| RA CAPITAL MANAGEMENT, L.P. | ABOS | Stock Option (Right to Buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | See Footnotes | |||
| RA CAPITAL MANAGEMENT, L.P. | ABOS | Stock Option (Right to Buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | See Footnotes | |||
| Ra Capital Management, L.P. | ABOS | Stock Option (Right to Buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | See Footnotes | |||
| Ra Capital Management, L.P. | ABOS | Stock Option (Right to Buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | See Footnotes | |||
| Ra Capital Management, L.P. | ABOS | Stock Option (Right to Buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | See Footnotes | |||
| Nathan B. Fountain | ABOS | Common Stock | Award | 186.4% | 35,500 | 54,550 | 03 Jun 2026 | Direct | ||
| Nathan B. Fountain | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| Kimberlee C. Drapkin | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | Direct | ||
| Kimberlee C. Drapkin | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| John A. Stalfort III | ABOS | Common Stock | Award | 19.2% | 35,500 | 220,624 | 03 Jun 2026 | Direct | ||
| John A. Stalfort III | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| Derrell Porter | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | Direct | ||
| Derrell Porter | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| Jeffrey L. Ives | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | Direct | ||
| Jeffrey L. Ives | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| George Golumbeski | ABOS | Common Stock | Award | 35,500 | 35,500 | 03 Jun 2026 | Direct | |||
| George Golumbeski | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| Laura Stoppel | ABOS | Common Stock | Award | 277.3% | 35,500 | 48,300 | 03 Jun 2026 | Direct | ||
| Laura Stoppel | ABOS | Stock Option (right to buy) | Award | 53,250 | 53,250 | 03 Jun 2026 | Direct | |||
| Ra Capital Management, L.P. | ABOS | Common Stock | Award | 46.5% | 6,060,606 | 19,103,785 | 16 Mar 2026 | See footnotes | ||
| Derek M. Meisner | ABOS | Common Stock | Sale | -1.19% | $6,813 | $3.26 | -2,090 | 173,999 | 06 Mar 2026 | Direct |
| Derek M. Meisner | ABOS | Common Stock | Options Exercise | 1.2% | 2,090 | 176,089 | 06 Mar 2026 | Direct | ||
| Derek M. Meisner | ABOS | Employee Stock Option (right to buy) | Options Exercise | -2.86% | -2,090 | 71,048 | 06 Mar 2026 | Direct | ||
| Derek M. Meisner | ABOS | Common Stock | Sale | -5.13% | $28,311 | $3.01 | -9,406 | 173,999 | 27 Feb 2026 | Direct |
| Derek M. Meisner | ABOS | Common Stock | Options Exercise | 5.41% | 9,406 | 183,405 | 27 Feb 2026 | Direct | ||
| Derek M. Meisner | ABOS | Employee Stock Option (right to buy) | Options Exercise | -11.4% | -9,406 | 73,138 | 27 Feb 2026 | Direct | ||
| Derek M. Meisner | ABOS | Common Stock | Sale | -1.51% | $8,017 | $3.00 | -2,671 | 173,999 | 28 Jan 2026 | Direct |
| Derek M. Meisner | ABOS | Common Stock | Options Exercise | 1.54% | 2,671 | 176,670 | 28 Jan 2026 | Direct | ||
| Derek M. Meisner | ABOS | Employee Stock Option (right to buy) | Options Exercise | -3.13% | -2,671 | 82,544 | 28 Jan 2026 | Direct | ||
| Derek M. Meisner | ABOS | Common Stock | Sale | -7.98% | $45,263 | $3.00 | -15,085 | 173,999 | 26 Jan 2026 | Direct |
| Derek M. Meisner | ABOS | Common Stock | Options Exercise | 8.67% | 15,085 | 189,084 | 26 Jan 2026 | Direct | ||
| Derek M. Meisner | ABOS | Employee Stock Option (right to buy) | Options Exercise | -15% | -15,085 | 85,215 | 26 Jan 2026 | Direct | ||
| Derek M. Meisner | ABOS | Common Stock | Sale | -3.14% | $10,718 | $1.90 | -5,633 | 173,999 | 23 Jan 2026 | Direct |
| Derek M. Meisner | ABOS | Common Stock | Sale | -0.58% | $1,939 | $1.84 | -1,054 | 179,632 | 22 Jan 2026 | Direct |
| Eric Siemers | ABOS | Common Stock | Sale | -0.35% | $1,629 | $1.82 | -895 | 255,371 | 22 Jan 2026 | Direct |
| Matt Zuga | ABOS | Common Stock | Sale | -0.55% | $3,138 | $1.86 | -1,687 | 304,924 | 22 Jan 2026 | Direct |
| Daniel Joseph OConnell | ABOS | Common Stock | Sale | -0.3% | $5,066 | $1.88 | -2,689 | 881,275 | 22 Jan 2026 | Direct |