SEC ownership of Tvardi Therapeutics, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001346830.

Holder evidence

50

Lead holder

Sporos Bioventures LLC

13D/G signal

Sporos Bioventures LLC

Latest evidence

31 Mar 2026

Issuer identity
CIK
0001346830
Location
Sugar Land, TX
Ownership snapshot
Latest large-stake holder
Sporos Bioventures LLC
Latest evidence date
31 Mar 2026

Ownership snapshot

Top shareholders of Tvardi Therapeutics, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Lead holder
Sporos Bioventures LLC
13D/G signal
Sporos Bioventures LLC
Evidence rows
50
Latest as of
31 Mar 2026
13D/G 13F 3/4/5 Lead comparable stake: 9% 13D/G row: Sporos Bioventures LLC Showing 1-8 of 50 holder rows.
Holder Evidence Ownership % Position 12M Net Δ As of
Sporos Bioventures LLC
13D/G
9%
$19,544,812
837,636 shares
$0 15 Apr 2025
Solas Tvardi Sidecar LLC
13D/G
8.1%
$4,050,047
761,287 shares
$0 15 Apr 2025
Slate Path Capital LP
13D/G 13F
Company
7.5%
$19,257,627
704,118 shares
$0 30 Jun 2025
David J. Tweardy
13D/G
7%
$3,470,757
652,398 shares
$0 15 Apr 2025
Ronald A. DePinho
13D/G
4.5%
$1,939,164
426,190 shares
$0 31 Dec 2025
Samuel D. Tweardy
13D/G
3.4%
$7,365,343
315,658 shares
-$14,730,686 07 Jul 2025
Vifor (International) Ltd
3/4/5 13D/G
10%+ Owner
2.2%
from 13D/G
$9,024,059
7,396,770 shares
20 Oct 2021
BlackRock, Inc.
13F
Company
13F
4.1%
$1,234,077
388,075 shares
31 Mar 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 30 May 2025.

Buys
$0
Insiders: 0
Sells
$0
Insiders: 0
Net
$0
Shares: 0
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 0
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 0 0 $0 $0 $0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 28 reporting-owner rows connected to Tvardi Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
28
Lead holder
CSL LTD
Net 12M change
$0
Latest report
29 Jan 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
CSL LTD 10%+ Owner $9,024,059 Mixed 09 Aug 2022
Vifor (International) Ltd 10%+ Owner $9,024,059 Mixed 20 Oct 2021
Shaheen Wirk Director $2,225,966 Mixed 17 Apr 2025
Wallace L. Hall Jr. Director $1,250,632 Mixed 17 Apr 2025
Chalmers Derek T. President & CEO, Director $1,209,514 Mixed 07 Sep 2021
Martin Vogelbaum Director $308,255 Mixed 04 Jun 2024
Jeffrey L. Ives Director $148,864 Mixed 04 Jun 2024
Lisa von Moltke Director $137,257 Mixed 04 Jun 2024
Helen M. Boudreau Director $112,985 Mixed 04 Jun 2024
Frederique Ph.D. Menzaghi Chief Scientific Off,Svp R&D $91,986 Mixed 01 Feb 2024
Harrison M. Bains Jr. Director $70,074 Mixed 01 Jun 2023
Christopher Posner PRESIDENT AND CEO, Director $62,268 Filing P/S 28 Feb 2025
Thomas Charles Reilly Chief Financial Officer $46,129 Mixed 03 Mar 2022
Joana Goncalves Chief Medical Officer $44,293 Filing P/S 05 Apr 2024
Scott Terrillion Sec'y; Chief Compliance & G.C. $34,224 Filing P/S 28 Feb 2025
Richard Makara VP, Head of Accting;Controller $16,571 Mixed 15 Jun 2022
Ryan D. Maynard Chief Financial Officer $7,425 Mixed 08 Feb 2024
Samuel D. Tweardy 10%+ Owner Mixed 07 Jul 2025
Michael S. Wyzga Director Mixed 17 Apr 2025
Sujal Shah Director Mixed 17 Apr 2025

Recent insider transactions for Tvardi Therapeutics, Inc.

Showing up to 300 most recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % Reported value Reported price Shares Shares owned Date Ownership
Avi Daniel Conn TVRD Employee Stock Option (right to buy) Award 45,000 45,000 29 Jan 2026 Direct
Stephen Paul O'Brien TVRD Employee Stock Option (right to buy) Award 15,000 15,000 29 Jan 2026 Direct
Imran Nizamudin Alibhai TVRD Employee Stock Option (right to buy) Award 115,000 115,000 29 Jan 2026 Direct
John Saewook M.d. Kauh TVRD Employee Stock Option (right to buy) Award 45,000 45,000 29 Jan 2026 Direct
Stephen Paul O'Brien TVRD Employee Stock Option (right to buy) Award 4,000 4,000 16 Dec 2025 Direct
John Saewook M.d. Kauh TVRD Employee Stock Option (right to buy) Award 17,500 17,500 16 Dec 2025 Direct
Avi Daniel Conn TVRD Employee Stock Option (right to buy) Award 17,500 17,500 16 Dec 2025 Direct
Imran Nizamudin Alibhai TVRD Employee Stock Option (right to buy) Award 47,500 47,500 16 Dec 2025 Direct
Samuel D. Tweardy TVRD Common Stock Other -100% -631,316 0 07 Jul 2025 By Trust
* indicates a reported price that failed the local validity check.
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